Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PWWP2AP1
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Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:80655194-80656793  UCSC
Coordinates (T2T) chr13:79884672-79886272  UCSC
Coordinates (hg19) chr13:81229329-81230928  UCSC
Strand +
Parental Sequence XM_005265812.3
Parental seq. overlap 1397 bp
Parental seq. overlap (%) 40.2%
Genomic Region Intergenic
Retrocopy Summary PWWP2AP1, located on chr13:80655194-80656793, is a retrocopy of the parental gene PWWP2A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PWWP2A
Full Name PWWP domain containing 2A
Also known as MST101
Coordinate chr5:160043538-160119484
Strand -
Gene summary Enables chromatin binding activity and histone binding activity. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PWWP2AP1
Bonobo Pan paniscus PWWP2AP1
Gorilla Gorilla gorilla PWWP2AP1
Orangutan Pongo abelii PWWP2AP1
Gibbon Nomascus leucogenys PWWP2AP1
Crab-eating macaque Macaca fascicularis PWWP2AP1
Rhesus Macaca mulatta PWWP2AP1
Golden snub-nosed monkey Rhinopithecus roxellana PWWP2AP1
Marmoset Callithrix jacchus PWWP2AP1
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.10.20.30.4
log10(TPM+1)

Related Sequence

>PWWP2AP1
TGGGGACTCCTTGGTGTGGCAGCTGACCCCGGGCTCGGAGGTGCAGGTCACGCTGCATTGAGGATGTGCTTATCTTGTCGTCCTCCGTCGGGTAGAAGCTCTTCTCCGGGGTCTTCGTGGATCTGTTCAAAAGAGATCATGAAACATTTGGTGCTATAGCCCAACTTTTGGTGGGAAACATATGCAGCTCTTCTGGTGATGCTGTTTGGGCCCGCATCCCTGTGACAGTATTTCCCAAAAGGGACTATAAAGATAACTCACAAGCCATGTAGCTTCAACGTCATACATTCCAAGAAGGGACGGAAGTCAAGTGTGAAGTTCATGGTACTGTTCCCAGTGACCTTTCTCCTGCCCTGCCTCATGTGCTAAGCTTGCCTGAAAGCCTGTGGACTTCCAAACCATCACCTCTTTCCCACGAAGGACCACCTTATCCTCCCTGCTTTATCAGAATCCATCTAACCAATCAGTACCTCAGCCCTCTCCTCAGAAAATTAAGCTGCCCAAACGAAAATATCTGGGGAAGAACCCACTTCAATAATAAATCCCATTAAACTATGACCTAGGCAAGTCCTATGCGATAAATGTTTAAAAAAAAATGCTGTTGTTGAAAACAAAATTAGAAAAGGTAGTAATGGAAGTGACTGCTAAATATGACGGTAAAAAACAGAGATATGAAAATGTACCTACTGTGAACAAAAAACTAAAAACTGGCCATAAAGTGGATGGAAAAACCCAAAATGAAAGCCAGAGAAGAAATACTGTGGTTATGGTTTCAGATACTGCTCACAGAAGAGGCAGAGTAGTAAATGTTTCTGCTCAGGCAGATAGGTCAAAAGCTCAGTTAAGTAATAACAAACTGCTCTAGAGTAAGAACATGGATCATGCAAAAGCTCAGGGAATTCTCAAAAATTGCCAAGGAAATGGCATGAAAGAAGCAAACTGAAACCTCTACTCCAAAAATGCACATTCAAAAGTCCATTTCACGGGTCAATATCAGAATCCTAGTCAGATGCCCTTCTGCCTGGGTTTCATTTAAAACCACAGAGGTACAGGAATGAAGAAAATGACTCGAGAAAGTGTGGAGTGGAGAAGTGGTCCTCAACTCCAGTCTTGCTGCACCTCTATGCGCTCACCAGGTGAGGGCCTTCTGAAAATCAGAGTCCCTGAAAAGGCCTGGAAGAGGCCAGCAGTGAGAGGTTCAGGACCCAACTGAAATGCATGCTCTTGGTGAACAAGATGAACCATAGACATTGGACAAAAAGGGCAGCAAAAGCATTATCTCTGGCCTTAAACCAAAAGAAATCTGACTCTTCCCGTGCTTCAGTGTGTAGCATTGATAGCATAGATGATTTGAAATCATCCAACTCTGAATGTAGCTCCTCAGAAAGCTTTCATTTGCCTCCAGGCAGTATGCATGCACCTTCCAAATCCTTCACTTCTTTCTCGTCAAAGGAAGAGAAAAAGTTCAGTAATTCCTTGAAAATGAATCTTCCAAAATTGTCTCTAAATGCATCACACCACATGGCAGGACCATATGTGTTGGGGAGATTGTTTCGGCCAAGATACATGACTTCCCTTGGTGCCAACCCCTGTTCTTACT
>XM_005265812.3
GAGGGGAAGGCCCAGGGAACCAAGCAGCGCTGTCGCCGCCGCCGCTGCAGCCGGAGTTGGAGGAGGGAGAAGCTAGGAAGAAAATggcggccgtggctgcagaggcggcagcgactgcagcgtcccccggggaggggggcgccggcgAGGCCGAGCCGGAGATGGAGCCCATCCCCGGCAGTGAGGCCGGCACTGACCCCCTCCCGGTCACGGCCACTGAAGCGTCTGTGCCGGATGGCGAGACTGACGGGCAGCAATCCGCTCCTCAGgccgacgagccgccgctcccgccgccaccgccgccgccgGGGGAGCTCGCCCGCAGCCCAGAGGCGGTGGGGCCGGAGCTGGAGGCTGAGGAGAAACTGTCCGTTCGGGTGGCGGAGTCGGCGGCAGCCGCGCCTCAGGGAGGGCCGGAACTTCCACCTTCTCCTGCATCGCCGCCGGAGCAGCCCCCGGCTCCCGAGGAGCGCGAGGAGCCGCCGCTGCCTCAGCCCGTAGCCCCGGCGCTCGTGCCGCCGGCGGGCGGGGACTCCACGGTGTCGCAACTGATCCCGGGCTCGGAGGTGCGGGTCACGCTGGACCACATCATTGAGGACGCGCTTGTCGTGTCGTTCCGCTTCGGGGAGAAGCTCTTCTCCGGGGTCCTCATGGATCTGTCCAAAAGAGACCATGAAACGTATGGTGCAATAGCCCTACTTTTGGTGGGAAAAATATACAGCCATTCTGGTGAAGCAGTTTGGGCCCCATGGTATCCCTGTGACAGTATTTCCCAAAAGGGAATATAAGGATAAACCAGAAGCCATGCCGCTCCAAAGTAATACATTCCAAGAAGGGACAGAAGTCAAGTGTGAAGCAAATGGTGCTGTTCCCGATGACCCTTCTCCTGTCCCGCATCCCGAGCTGAGCTTGGCTGAAAGCCTGTGGACTTCCAAACCACCACCTCTCTTCCATGAAGGAGCACCTTATCCTCCCCCTTTGTTTATCAGGGACACATATAACCAATCAATACCTCAGCCACCTCCTCGGAAAATTAAGCGACCCAAACGAAAAATGTACAGGGAAGAACCCACTTCAATAATGAATGCTATTAAACTACGACCCAGGCAAGTTCTGTGTGATAAATGTAAAAACAGTGTTGTTGCTGAAAAAAAGGAAATTAGAAAAGGTAGTAGTGCAACTGACTCTTCTAAATATGAAGATAAaaaacggagaaatgaaagtgtaactactgtgaacaaaaaactgaaaactgaCCATAAAGTGGATGGGAAAAACCAAAATGAAAGCCAGAAAAGAAATGCTGTGGTTAAGGTTTCAAATATTGCTCACAGCAGAGGCAGAGTAGTAAAAGTTTCTGCTCAGGCAAATACATCAAAAGCTCAGTTAAGTACTAAAAAAGTTCTCCAGAGTAAGAACATGGATCATGCGAAAGCTCGGGAAGTGTTAAAAATTGCCAAAGAAAAGGCACAAAAGAAGCAAAATGAAACCTCTACTTCCAAAAATGCACATTCAAAAGTCCATTTCACACGTCGATATCAGAATCCTAGCTCAGGTTCCCTTCCACCCCGGGTTCGTTTAAAACCACAGAGGTACAGGAATGAAGAAAATGACTCTTCTCTGAAGACAGGACTTGAGAAAATGCGGAGTGGCAAGATGGCACCCAAGCCCCAGTCTCGCTGCACCTCTACCCGCTCAGCAGGTGAGGCCCCTTCAGAAAATCAGAGTCCCTCAAAAGGCCCTGAAGAGGCCAGCAGTGAGGTTCAGGACACAAATGAAGTGCATGTGCCTGGTGATCAGGATGAACCACAGACATTGGGCAAAAAGGGCAGCAAAAACAATATCTCTGTTTATATGACCCTAAATCAAAAGAAATCTGACTCTTCCAGTGCTTCAGTGTGTAGCATTGATAGCACAGATGATTTGAAATCTTCCAACTCTGAGTGTAGTTCTTCTGAAAGCTTTGATTTTCCTCCAGGCAGTATGCATGCACCTTCCACCTCCTCCACTTCCTCCTCTTCAAAGGAAGAGAAAAAGCTCAGTAATTCCTTGAAAATGAAAGTCTTTTCCAAAAACGTCTCTAAATGCGTCACACCAGATGGCAGGACCATATGTGTAGGGGACATTGTTTGGGCCAAGATATATGGCTTCCCTTGGTGGCCAGCCCGTATTCTTACTATAACTGTGAGCCGGAAAGATAACGGCCTTTTAGTCCGACAGGAGGCCCGTATTTCATGGTTTGGGTCTCCAACAACATCTTTCCTTGCTCTTTCACAACTCTCCCCCTTTTTAGAAAACTTCCAGTCACGCTTTAATAAGAAGAGAAAGGGCCTGTATCGCAAGGCTATCACAGAGGCAGCTAAGGCTGCCAAGCAGCTGACCCCCGAAGTGCGGGCTTTGTTGACACAGTTTGAAACGTGAACATGGGCAGTAAGGTAGGCAAGACCATTGGAAGTCACCACAGATTTTCTAGTCTAGTTAGGAATAATTTCTACAAAATAGCGTGGCCAGATTGGAGAGAGAAGTTGCACTCAGTTGGCTGGCTTTTTAATACTTACCTTATAGCCATTTTTAGACTGAGAGCTTAAACTGAACATATAATCAAATTTTGTGTTAAGGAAGTGAGATTTTAGCAGTATTTTTCAGTTTTGAAGTTCGAAACCATCCCAAGGCATAGGAGCCATAGCCTCAACTGAAATTGAATTTTTGTAGGGACTGTTAATTGCCATTTGTACCTAATACTGtatatatacatatatatacgtgtgtgtgtgtgtatatatatatatccgtgtatgtatatatacacacatatatatgtatatatacacatatatatatatGAAATACAGCCTGTCACTGTGTGACACAGATTGCATATTTGGGATTGCAATAAGGGCTTGGTGAGCTGGGGGAATAGTGGATATTTAATGACTACTTGTTTTTTAAATAATGAACACTTAGCCTTTCTATGCGCATAATGGTGTAAAAGTTAGATGGTTAGGTGTTTGACAAACAGATGGTTGCAATTCAGTTACAGACTGGGGAAATAGCCCAGTGTTTGGGATTAAAACTGTCAAGACTGGATAGGTGTTAGTCATCACTGTCTTTCGTCCAGTGGGGATTTAATAAATACTTTCAAGCTTCTGGTTTGGGAGTTTAGATAGGTTTGATTTTGGATTTGTAAATAGTGATTGCTAAATTTGGTCAGATTTCTCCTGACTGGCTGTTCCTAAATTCTTAGGATATGTCCCAGTAAAATTATACTTTGTGAATTAATTGTCATATGTGTAATTGTTGCATTTTGGATGTACCTAATTTGATAATTAAAACAAAATAATTTCCGTTTAAGGTATCTGTTTGCAGGTCAGAAAATGAGAAAATGTAATTGTGTAATGCTCTGAAATGTaaaaaaaaaaaaaaaaaccaaaaaaaaGCTGTAAATAAAATCAACTAAATCCAAA

Publications

PMID - Link Title
No publications available for this retrocopy