Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FAR1P1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:90170862-90175441  UCSC
Coordinates (T2T) chr13:89375242-89379820  UCSC
Coordinates (hg19) chr13:90823116-90827695  UCSC
Strand +
Parental Sequence NM_032228.6
Parental seq. overlap 4202 bp
Parental seq. overlap (%) 79.2%
Genomic Region Intergenic
Retrocopy Summary FAR1P1, located on chr13:90170862-90175441, is a retrocopy of the parental gene FAR1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FAR1
Full Name fatty acyl-CoA reductase 1
Also known as CSPSD|MLSTD2|PFCRD|SDR10E1
Coordinate chr11:13668666-13732346
Strand +
Gene summary The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAR1P1
Bonobo Pan paniscus FAR1P1
Gorilla Gorilla gorilla FAR1P1
Orangutan Pongo abelii FAR1P1
Gibbon Nomascus leucogenys FAR1P1
Green monkey Chlorocebus sabaeus FAR1P1
Crab-eating macaque Macaca fascicularis FAR1P1
Rhesus Macaca mulatta FAR1P1
Baboon Papio anubis FAR1P1
Golden snub-nosed monkey Rhinopithecus roxellana FAR1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FAR1P1
cTATCTACCACCTGTGGATCCCAAGAAGCTGATTGATTCTTTAGAGTGGATGGATTATGGCCGAGTAAATGATATCATGCGAAAGTTGATAGGAGACAGACCTGACACATACATAGACACAAAAGCGTTGGCAGAATATGTTGTACAACAAGAAGGAGCAAAGCTAAATGTGGAGATTGTAAGGCCGTCTATTGTTGGTGCCAGTTGGAAAGAACTTTCCAGGATGGATTGATAACTTTAATGGACCAAGTGGTCTCTTTATTGTGGCAGGGAAAGGAATTCTTTGAACAATGCGCGTCTCCAATAATGCCCTTGAAGATCTTGTTCCTGTAGATGTAGTTGTCAACAACAGTCTTGTGGCAGCCTGGTATTCCGGAGTTAATAGAACAAGAAACCTCATGTCATATAATTGTACAACAGATAGCACTAATCATTTCCACTGGGGTGAAGTTTAATACCATGTAATTTCTACTTTCAAGAGGAATCCTCTCGAACAGGCCTTCAGATGGCCCAATGTAAATCTAACCTCCAATCACCTTTTATATCATTACTGGATTGCTGTAAGCCATAAGGCCTCAGCATTCCTGGATGATATCTACCTCAGGATGACTGGAAGAAGCCCAAGGATGATGAAAACAATAATTCATCTTCACAAAGCTGTGATGTTACTTGAGTATTTCACAAGTAATTCTTGGGTTTGGAATACGGACAATGTCAATATGTTAATGAATCAACTAAACCTTGAAGATAAAAAGACTTTCAATATTGATGTACGGCAGTTACATTAGGCAGAATATATAGAGAACTACTGCATGGGAACTGAGAAGTACATATTGAATAAAGAAACGTCTGGCCTCCCTGCAGTCAGAAAACATCTGAACAAGTTGCATAATATATCTTATGATTTTAATACTATCCTTGTGATCCTCATCTGACACATTTTTATTGCAAGACCACAAATGGCAAGAAACATCTGATACTTTGTGGTTAGTCTGTGTTACAAGTTTCTGTCATAGTTTCAAGCATCCAGCACTATGAGATACTGAAGACCAAGAACTCAGCATTTGAACATCTATGCCTGTGGTGGACTAAATGCACAAAATATAAAATGTACTTAAGTCATTTCACCTTTTGTCATGACATTAAACCATCTTAGATTGGAGTGTGAAGTAAATTATGGTACATTTTATGTAACATTTTAATGTTTATGCTCATAAAACCTAGTGAACACACTGTGTTTTGCCAGCTCTAATCTACAATAGCTACCAAAACCATGACTTAATATTTTGAGCCCTGGAAGAAAGTGGTGGGATGAAGGCAAGAGTGGGGAAATGGGAACACTAACCAGTATAACTGCAATTCTGGAACATAATTAAAATATGTCTGAACATATAGTGAATTTCTAATTCTAATGTTCAGTGCAATGGAAGATATTTATTTGGACAGTAATACTAGCTAAGTTGGTAGATATTTGATTCTTCAGTGTCTGATTTTTTTCATTAGTTGAAGTGGGTTTTAATTTTGTTAAAATTATAACCAACCTATTTTCACATCATCCTGTAAGTTAAATGATATCCAACATGAAAGACATGTTCTCATTTTTCTTTTCTGATTAAATGTCTGATGCATATCATTTTTCTATAAGCAATCAGCTGCTTTTAAAATCAGAATGCTATGTTACTCTAGTGACTGTACTGGTTCTGAATGGGTTTGAGAATCCACATCAACAACATATGCTACGTGTTTTTTTGATGGAAAGTGAAAACAAATTCAGTAAAACTGTTACTATCAAAAAGAATAGAAATACAGTTTTCTTGCCCACATTATGATCAAATAAAAATCCTGTGAAATTGTGTTTATGTTTTGAAGCAGGAGGATTTCTTAAGACTTTGTTGGAAGTGGGAGCATTCACCATACTTGTGTTCTCCTCCCTGTATAAATTTTATTCATAGGACTTTAAAAAGGCTTGTGCTATCTTTCTGATGAAAACTACAAGTGTGTTATTATGGAAGAATGTATTTGCAGGTAGTAATAACATTAAGAAAATATTCTCATGTGTAAACACATACTAATTTTGACCTTGAAAGATGAATTCCTTCAAGAAAAAATAAAATAATGCATAAGATAATGTGTATGAAATTAAATAAAAGACTTTATTTACATACCACATAAAGTAGCAAACTGTTGAATTAGTTTGAAGATATTTATTTTTTATACATATAGTTTTAGGTTTAGAAAGAAATGCATTATAGAAACAAGTAATAACAAGAAAATTGATGTATATTTTGAGGATACATTAAAATTCCCTTTTAGTCATAATAGTTAGCTCTACCTACTGTTTTAACATACATTTGGTTTCACAGTTTGTTCATCATAACACTTCTAATTAAGTTGATCAAGTTGTACTGTATTAAATAATCAGCAATGTATCTGGAGTATGTTTAAAGAGAACAGTTCACAATACAAAAAGTTACATGGAACTTTACATCTTACATTTCTTGTCAATTTAAATGCAATATATAAGAAGTCTATTTTGCTATTGTGAAAAAACTAAATGTAGAGGAAATCACCTACTTTCATGCAGGTGTATAATCTTGAAAAGGAAAAATGCTTCCATGTTGAAGCCAGACTTTCTGTAGTAAAACTCTTAAATATTATTTTAAAAGAAATATGTATATAAATATCTCTATATTCTTTGGAATGATACTAAAGTCTCTGGCCTTGGACCTACCTGATATAAAGGTATAAGTTACCATGGCAATGTCTGAAAGTTGAATAAATAATGATGCCTTTGATTTAAAGTGGCCCACATAATATACATCGAGTACTCCATCTCTCCAAATGTATTTCCATAATGTGTTGAAACCATGCTAACATTTGCATGATTTTTGTATTTCTGCTGAATAGACTTAGAATCAGGTGAATTGTCTTTGTGTCTTGCAAAAGAGTTGGGGACAACTTGGGCAGACCTATGAAGTGCATAGTGTGTGTCTTCTGAAATGTTTTACTGTTCTTGTAATCTGACTTAAAGAAATGTTAACTGGGAGGGTGCTGAGGCCACTGCATTAATTCTGTGTGTTTAGAATTCTGTTGTCAAAAGTAAACTAATGAATAAATTAGTTTGTCTTTCTGGAATTTAAAGTTCTAAAATTAGTATAAAGAGTATATAGATCATTAATCCCCACCTACTAGACTTTGAACTTAAGTCAAACTTGAACATTTGAGAAATCATTTGTGTCATTTACTAGACATGATTTTTAGCTCTGTTTGACTACGTTTTCTACACAAACTCATTATTTAACAGGATAGACTACTAAATTAAATGTTTCTTATTTCATTTAACTCATTTGATTAAACTGCATTCTAGAACATTTGGAGTTTTTCCCCCTATTCATCCTTAATCCTGGCATATGCATTTGTAAATTGTGATGCCATTGGGACTATATTTAAATTTGATTTGGCAACATTAGCATGTCCTAAGACTCAGTGCAGAGAAGCATGGCAGTATGTCCTTTGACTTAAGGATGGCATAAAATAATCATTTTTGAACCTGTGTAATAAAGCTTGAAAGCAGGGAAAATAATTTCCTTTTCCCCCTTTTCTGTGCTGTCTGTAGGAATTGATTTGGAATTTTTTTTAATTATACTTTTTTATTTTGTTTTAAAAGTAAATTGATAATCTTTTATAAGAAGTAAATAGAAATATTATTGGGTGTCTTTGATTGTAAAGCAAAAAGTAATAAATGAATCCCTGTATTTCCATTATTTATTGTATTTTTATGTTCTGAAAATTGTCTATGAAACAATATGGATAGGATTACAGGAAGCAGTCCTTACTTAAACTTCTTGTCTGCTTTGGGTGTACTTGTTAATTCTTATGTCCTAATTTTATTTAATTCTGTGTTGCGCACACGGCATTTTAGGGGAAGCATACAGGCAGGATGAACACTTTCTGTTAAAGTGTTATTTTTATGTTTTACCTGGAATGAGGCAGGTTTTTTTCTGTTTCCTAAAAACAGTAACCAAGAGACCTCCAGGGTGTCATTAGGTTCCAGCTGCTGTCCTCCATATTGAATGATATCCTGTTAATTTATAGGTATATTTGTAGTAATTCATATGTCTATTAAGTAAGTATAAGAGATAATTCATTAGTAATAGAAATTAACTGAACCCTTTTGGAGCAGGTGAGAGTATCAGGCAGGGGTCAGGTAAGTGTAAACGGCCTTCTGAGCATGCTCTTCCAGGCTGACTGCCAGCCCTGACTTGAAACCGTTAGCACTGACTTGCTCTGTTTAGAGAAAATCTTTCCAAACTTTTGCATGATAAACTAGAAAAAGGAATATATGCCACGTAACTGGATTACAGAAGTGAGTTAATTAATAGTTTCTCTCATAAAAGATATATGAAATATTTTCTTATTGAATTAATATTTTTGGTCTTGAAGCATTTTCTTGTAGTAGAATGTATTTGTCTTTTTTCCTGGTGTTACCCTCTTAGCATGTATCTTTGCTACCCTGAAGATCCTTTTAAACAAATCATCTTTGTCAGTTAAGAATAGTTGTGCAAAAATTGTTAAAT
>NM_032228.6
GCCACTGCCCGTCCGCTCTTCAGCAGCCGGTCGCGGGCGGTGGAAAAGCGAGTGAAGAGAGCgcgacggcggcggcggcggcggcgCAGCTATTGCTGGACGGCCAGTGGGAGAGCGAGGCCTGAGCCTCTGCGTCTAGGATCAAAATGGTTTCAATCCCAGAATACTATGAAGGCAAGAACGTCCTCCTCACAGGAGCTACCGGTTTTCTAGGGAAGGTGCTTCTGGAAAAGTTGCTGAGGTCTTGTCCTAAGGTGAATTCAGTATATGTTTTGGTGAGGCAGAAAGCTGGACAGACACCACAAGAGCGAGTGGAAGAAGTCCTTAGTGGCAAGCTTTTTGACAGATTGAGAGATGAAAATCCAGATTTTAGAGAGAAAATTATAGCAATCAACAGCGAACTCACCCAACCTAAACTGGCTCTCAGTGAAGAAGATAAAGAGGTGATCATAGATTCTACCAATATTATATTCCACTGTGCAGCTACAGTAAGGTTTAATGAAAATTTAAGAGATGCTGTTCAGTTAAATGTGATTGCAACGCGACAGCTTATTCTCCTTGCACAACAAATGAAGAATCTGGAAGTGTTCATGCATGTATCAACAGCATATGCCTACTGTAATCGCAAGCATATTGATGAAGTAGTCTATCCACCACCTGTGGATCCCAAGAAGCTGATTGATTCTTTAGAGTGGATGGATGATGGCCTAGTAAATGATATCACGCCAAAATTGATAGGAGACAGACCTAATACATACATATACACAAAAGCATTGGCAGAATATGTTGTACAACAAGAAGGAGCAAAACTAAATGTGGCAATTGTAAGGCCATCGATTGTTGGTGCCAGTTGGAAAGAACCTTTTCCAGGATGGATTGATAACTTTAATGGACCAAGTGGTCTCTTTATTGCGGCAGGGAAAGGAATTCTTCGAACAATACGTGCCTCCAACAATGCCCTTGCAGATCTTGTTCCTGTAGATGTAGTTGTCAACATGAGTCTTGCGGCAGCCTGGTATTCCGGAGTTAATAGACCAAGAAACATCATGGTGTATAATTGTACAACAGGCAGCACTAATCCTTTCCACTGGGGTGAAGTTGAGTACCATGTAATTTCCACTTTCAAGAGGAATCCTCTCGAACAGGCCTTCAGACGGCCCAATGTAAATCTAACCTCCAATCATCTTTTATATCATTACTGGATTGCTGTAAGCCATAAGGCCCCAGCATTCCTGTATGATATCTACCTCAGGATGACTGGAAGAAGCCCAAGGATGATGAAAACAATAACTCGTCTTCACAAAGCTATGGTGTTTCTTGAATATTTCACAAGTAATTCTTGGGTTTGGAATACTGAGAATGTCAATATGTTAATGAATCAACTAAACCCTGAAGATAAAAAGACCTTCAATATTGATGTACGGCAGTTACATTGGGCAGAATATATAGAGAACTACTGCTTGGGAACTAAGAAGTACGTATTGAATGAAGAAATGTCTGGCCTCCCTGCAGCCAGAAAACATCTGAACAAGTTGCGGAATATACGTTATGGTTTTAATACTATCCTTGTGATCCTCATCTGGCGCATTTTTATTGCAAGATCACAAATGGCAAGAAATATCTGGTACTTTGTGGTTAGTCTGTGTTACAAGTTTTTGTCATACTTCCGAGCATCCAGCACTATGAGATACTGAAGACCAAGGATTCAGCATTAGAACATCTATACATATGGTGATCTAAATGTACAAAATGTAAAATGTATAAGTCATCTCACTTTTTGTCAAGACATTAAACCATCTTAGATCGGAGTGTGAAGTAAATTATGGTATATTTTATGTAACATTTTAATGTTTATGCTCATAAAACTTAGTGAACACACTGTGTTATGCCAGCTCAAATCTACAGTAGCCACCAAAACCATGACTTAATATTTTGAGCCCTAGAAGAAAGGGGTGTGCTGAGGACAAGAGTGGGGAAATAGGAACACTGACCAGTATAACTGTGCAATTCTGGAACATATTAATTAAAATAATATGCCTTAACATATAGTGAATTTCTAATTCTAATGTTCAGTGCAATGGAAGACATTTATTTGGACAGTAATACTAGCAAAGTTGGTAGATATTTGATTCTTCATTTTTTGTTTTTTTCATTAGTTGAAGTGGGTTTTAGTTTTGTTTAAAATTATAACCAGCGTATTTTCACATCATTCTGTAAGTTAAATGATATCAAACATGAAAGAGATGTTCTCATTTTTCTTTTTCTGATTAAACGTCTGATGCATATCATTTTTCTATAAGTAATCAGTTGCTTTTAAAATCAGAAGGCTATATTATTCTAATGACCCTATTCGATCTAAATGGGTTTGAGAATCCATATCAGCAACATACGTGTTTTTTGACAGAAAGTGAAAACAAATTCCGTAAAACTGTTAGTATCAAAAAGAATAGGAATACAGTTTTCTTTTCCACATTATGATCAAATAAAAATCTTGTGAGATTGTTTATGTTTTGAAGCAGGAGGATTTCTTGAGATTTGATGGAAGTGGGAGTTGGGAAGGATTCACCATACTTGTGTTCTCCTCCCTTTATAAATTTTATTCATAGGACTTTTAAAAGGCTTGTGCTATCTTTCCAGTGAAAACTGAAAGTGCATTATTATGGAAGAATGTATTTGCAGGTAGTAATAGCATTAAAAAATATACTCGTGTGTAAACACATACTAATTTTGACCTTGAAAGATGAATTCCTTCAAGAAAAATAAAATAATGCTTAAGATAATGTGTACGAAATTAAATAAAGGACTTTATTTACATACTACATAAGGTAGCAAACTGTTGAATGAGTTTGAAGGTATCACTTATTTTTTATGCATGTGATTTTAGCTTTAGAAAGAAATGCGTTATAGAAACAAGTAATAGCAAGAAAATTGATGTATATTTTAATGATACATTAAAATTCCCTTTTAATCATAATAGTTAACTCTACTTACTGTTTTAACATACATTTGATTTAACAAATTGTTCAGCATAACACTTCTAATTAAGTTTATCAAGTTGTACTGTATTAGATAATCAGCAGTGTATCTGGAGTATGTTTAAAGAGAACAGTTCGCAATACAAAAAGTTACATGGAGCTTTACATCTTAACTTTCTTTGTCAATTTAAATGCAATGTATAAAAAGTTTATTTTGCTATTGTGAAAAACTAAATGTAAAGGAAATCACCTACTTTCATGCAGGTGTATAATCTTGAAAAGGAAAAATGCTTCCATGTTGAAGCCAGATTTTCTGTAGTAAAACTTTTAAATATTATTTTAAAAGAAATATGTATATAAATATCTCTATATTCTTTGGAATGATACTAAAGTCTCTGGTCTAGGACCATACCTTATATAAAGGTATAAGAGACCATGACAATGTCTGAAAATGGAATAGATAATGATGCCTTTTATTTAAAGTGGCCCACATAATATACATTGAGTACTCCATCTCTCCAAATGTATTTCCATAATGTGTTGAAAACATGCTAACATTTGTATGATTTTTATACTTCTGCCGAATAGACTTAGAATCAGATGAATTGTCTGTGTGTCTTGCAAAAGAGTTGGGGACAACTTGGGCAGGCCTATGAAGTGCATAGGGAGTGTATGTCTTCTGAATGGTTTTATTGTTCTTGTAATCTAGCTTAAAGAAATGTTAACTGGGAGGGTGCTGAGGCCACTCACTGCATTAATTTTGTGTGTTTAGAGTTCTGTTGTCAAAAGAAAACTAATGAATAAATTAGTTTGTCATTCTAGAATTTAAAGTTCTAAGATTAGTATAAAGAGTATATAGATTGTTAATCCCCACCAGCTAGACTTTGAACTTAAGTCAGACTTAAAGATTTGAGAAATTATTTGTGTCATTTACTAGACGTGATTTTTAGTTCTGTTTGATTATATTTCCTACACAAACTTCTTATTTAACAGGATAGCCTACTAAATTAAATGTTTCTTATTTCACTTAACTCATTTGATTAAACTGTATTCTAAAACATTTGGGGTTTTTCCCCCTATTCAGTTTTAATCTTGGAATATGCATTTGTAAATTGTGATGTCATTGAGACTATATTTATATTTGACTTGGCAACATTAACATGTCCTAAGACTTAGTGCAGAGAAGCTTGGCAGTACGTTCTTTGACTTAAGGATGGCATAAAATAATCATTTTTGAACCTGTGTAATAAAGCTTGAAAGCAGGGAAAAGAATTTCCTTTTCCCCCTTTTTTGTGTTGTCTATAGGAATTAACTTGGGATTGTTTTGTGGGTTTTTGTTTGTTTTAAATGTAAATTGAGAATCTTTTATAAGAAATAAAAGCATTATTGGGTGCCTTTGTTTGTAAACCAAAAAGTAATAAATGAATCCCTATATTTCCATTATAGTATTTATTGTATTTTTATGTTCTGAAAATTACCCATGGAACAATATGCTTAGGATTACAGGAAGCAGTCCTTACTTACACTTCTTGTCTGTTTTAGGTGTACTTGTTAATTCTTATGTCCTAATTTTATTTAATTCTGAGTTCCTTACACAGCATTTTAGGGAAAGAATACAGGCAGGATGACACTTTGTGTTAAAGTGTTATTTTTATGTATTACCTGGAATGAGGCAGGTTTTTTTCTGTTTTCTAAAAAGAGTAACCAAGATACCTCCAGGGTGTCATTGGGTTCCAGCTGCTCTCCTCCACATTGAATGATATCTTGTTAATTTATAGGCACATTTGTGGTAATTTATATGTCTATAGAGTAAGTATAAGAGATAATTCATTAGTAATAGGAATTAACTGACCCCTTTTGGATGGGGGAGAGCATCAGGCTGGGGTCAGGTAAGTGTAAATGGCCTTCTGAGCATGCTCTTCTAGGCTGACTCCCAGCCCTGACTTGAAACCATTAGCGCTAACTTGCTCTGTTTTGAGAAAAACTTTCCAAACTTTTGCATGAGAAACTAGAAAAAGGAATGTATGCCACGTAACTGGATTACAGAAATGAGTTAATTGTCTCTGTGATAAAAAAAAAAAATGAAATATTTTCTTATTGAATTAATATTTTTGTCTTGAAGCATTTTCTAGTGATAGAATGTATTTGTCTTTTTTCCTGGTGGTACCCTCTTAGCATATATCTTTGCTATCCTTAAGATCCTAAACAAATCATCTTTGTCAGTTAAGTATAGTTGCGCAAAAATTGTTAAATCCTTTGTCTTTATTAAAGAAAAATTTGAGTAACATTAA

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