Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BRD7P5
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:94757309-94759406  UCSC
Coordinates (T2T) chr13:93960815-93962912  UCSC
Coordinates (hg19) chr13:95409563-95411660  UCSC
Strand -
Parental Sequence XM_011523048.2
Parental seq. overlap 1913 bp
Parental seq. overlap (%) 83.2%
Genomic Region Intergenic
Retrocopy Summary BRD7P5, located on chr13:94757309-94759406, is a retrocopy of the parental gene BRD7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BRD7
Full Name bromodomain containing 7
Also known as BP75|CELTIX1|NAG4|SMARCI1
Coordinate chr16:50315957-50368988
Strand -
Gene summary This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BRD7P4
Bonobo Pan paniscus BRD7P4
Gorilla Gorilla gorilla BRD7P4
Gibbon Nomascus leucogenys BRD7P3
Green monkey Chlorocebus sabaeus BRD7P1
Crab-eating macaque Macaca fascicularis BRD7P4
Rhesus Macaca mulatta BRD7P4
Baboon Papio anubis BRD7P4
Golden snub-nosed monkey Rhinopithecus roxellana BRD7P5
Marmoset Callithrix jacchus BRD7P2
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BRD7P5
CGCGCCGCCCCCTTGCCTCCGGCGCGCAGGGCCTCTAAGGGGCCGCTCCCGCCCTGCGCGGGCCTGGCCTGGACCGGAAGCTGCGCTGCGTGCCTGCTCCTGGCTCTGGGGGCGGGCACCGGGGCCAGCTGGACAGGGGCAAGAAGCACAAGGAGCGCAAGTCAGACAAACACTTCTATGAGGGGTATGTAGAGAAGCCCTTGAGGCTGGTCCTCAAAGTAGGAGGGAACGAAGTCACCGAATTCTCCACGGGCAGCTCAGGGCACGACTCCAGCCTCTTCGAAGGCGAATAAGATCATGACAAATACAAGGACAGAAAGCAGAAAAAGAGAAAGAAAGGAGAGAAGCAGGATCCAGGGGAAGAAAAAGAGAGAAAACGGAGGAGAGTTAGGGAGGATAAAAAGAAGCGAGATCGAGACCTTGTGGAGAATGAGGCAGAAAAAGACCTCCAGTGTCATGCCCGTGTGAGATCCTCTCACAAGCTCTTTAGCCAAACAAGAAGAAGTAGAACAGACACCCCTTCAAGAAGCTTTGAATCAACTGATGAGACAATTGCAGAGAAAAGACCCAAGTGCTTTCTTTTCATTTCCTGTGACTGATTTTATTGCTCCTGGCTACTCCATGATCATTAAACACCCAAGGGATTTTAGCACTATGAAAGAAAAGGTCAAGAACAATGACTACCAGTCGATAGAACTAAAGGATAACTTCAAACTAATGTGCACTAATGCCATGATTTACAACAAACCAGAGACCATTTATTATACAGCTGCAAAGAAGCTGTTGCACTGGGGGATGACTATTCTTAGCCAGGAAAGAATTCAGAGCCTGAAGCAGAGCATAGACTTCATGGCTGACTTGCAGAAAACTCGAAAGCAGAAAGATAGAACAGACTGGGGAGGATGGAGGCAGAGTGGGGAGGACGAAGGCTGCTGGCCCAGGGAGAGAGGACTCTGGAGATGCCGAAGCACAAGCCTTCCAGAGTCCCGGCAAAGAAAATTAAAATATAGACAAAGATATGCTTGAAGATAAGTTTAAAAGCAATAATTCAGAGAGAGAGAGCAGGAGCAGCTTGACCAAGTTATGAAGGAATCTGGAGGAAAGCTGACCAGACAGCCTGTGAACCGTCAGTGTGAATTTGAAAGAAGAAAACCAGATGGAACAACAACGTTGGGACTTCTCCACCCTGTGGATCCCATTGCAGAAGTGTGAGACTTGAATTCTGGACCTACAGTTCTTATGCACCACGTATGACTCCACGTTTACAAATATCAGCAAGGATCATTCTGATTTAATCTATCCAACCTATGGGGAAGACTCTGATCTTCCAAGAGATTTCAGCATCCATGAGTTTTGGGCCACATGCCAAGATTATCCATATGTTATGGCAGATAGTTTACTGGATGTTTTCACAAAAGGAGGGAATTCCAGGACCCTACAAGAGTTGGAGATGTCATTGCCTGAAGATGAAGGCCATACTAAGACACTTGGCCCAGCAAAAGAAATGGAGATTATAGAACTAGACCCAGCAGGGCATCTGGACCCCAATACTCAAGACAGGCTCACACACTGAAAGTAGTAAACTTTGGCGCTCCAGTTGAAGTTTTTGACTCTGAAGAACCTGAAGTATTCAGAAGAAACTTGATGAGGCCACCAAATTGTTCAGGGAGCTCCAGGAAGCCCGGAACGAGCATTTGAGCACCAGACCCCCTCCCAGTATGATCTGTCTCTTGGGTGCCTCCTGCAGAGAAATGCATCTCACTGAACAAGTGACCAATAATCTTAAAAACTTGCACAGCAAGTAACTCCAGGTGATATTGTAAGCCTGTATGAATTTCAAAAAGCAATGGGGATTTCCATTCCTTCCCCCAGCATGGAAAACAATTTTGTAGATTTAACAGAAGATCTTGAAGAACCTAAAAAGATGGATGTTGCTGAGTGTGGACCTGGTGGGAGTTGAAGCACATGGTATTTGATTATATATTATGTATATACTTTTTCATTCTTAACTTAGAAATGCTTTTCAGTAGATATTAAATATTTGCAAATTGTGTTTTTAGTTAAACTTTGGAACAGTGAATTTGAATGTTCCAGAGGG
>XM_011523048.2
TCGGGCTCCGGCCGGGTCTCGCGCGCCGTCTTCTCGAGAGGGGCATCGCGCCGCCCGGCGCGCGCCGCCCCCCTGCCTCGCGGCGCGGGGTCTCGCGGGCCCCGCTCCCGCCCTCCGCTCGCCTggcccggaccggaagcggcgccgcacggcctgggcctggcgcggggggcgggcaccggggcccggTCGGACATGGGCAAGAAGCACAAGAAGCACAAGTCGGACAAACACCTCTACGAGGAGTATGTAGAGAAGCCCTTGAAGCTGGTCCTCAAAGTAGGAGGGAACGAAGTCACCGAACTCTCCACGGGCAGCTCGGGGCACGACTCCAGCCTCTTCGAAGACAAAAACGATCATGACAAACACAAGGACAGAAAGCGGAAAAAGAGAAAGAAAGGAGAGAAGCAGATTCCAGGGGAAGAAAAGGGGAGAAAACGGAGAAGAGTTAAGGTACAAGTGGTTACATTGCTTTGGCTTTGCGGACGGCACTGCCTCTTCCAGGAGGATAAAAAGAAGCGAGATCGAGACCGGGTGGAGAATGAGGCAGAAAAAGATCTCCAGTGTCACGCCCCTGTGAGATTAGACTTGCCTCCTGAGAAGCCTCTCACAAGCTCTTTAGCCAAACAAGAAGAAGTAGAACAGACACCCCTTCAAGAAGCTTTGAATCAACTGATGAGACAATTGCAGAGAAAAGATCCAAGTGCTTTCTTTTCATTTCCTGTGACTGATTTTATTGCTCCTGGCTACTCCATGATCATTAAACACCCAATGGATTTTAGTACCATGAAAGAAAAGATCAAGAACAATGACTATCAGTCCATAGAAGAACTAAAGGATAACTTCAAACTAATGTGTACTAATGCCATGATTTACAATAAACCAGAGACCATTTATTATAAAGCTGCAAAGAAGCTGTTGCACTCAGGAATGAAAATTCTTAGCCAGGAAAGAATTCAGAGCCTGAAGCAGAGCATAGACTTCATGGCTGACTTGCAGAAAACTCGAAAGCAGAAAGATGGAACAGACACCTCACAGAGTGGGGAGGACGGAGGCTGCTGGCAGAGAGAGAGAGAGGACTCTGGAGATGCCGAAGCACACGCCTTCAAGAGTCCCAGCAAAGAAAATAAAAAGAAAGACAAAGATATGCTTGAAGATAAGTTTAAAAGCAATAATTTAGAGAGAGAGCAGGAGCAGCTTGACCGCATCGTGAAGGAATCTGGAGGAAAGCTGACCAGGCGGCTTGTGAACAGTCAGTGCGAATTTGAAAGAAGAAAACCAGATGGAACAACGACGTTGGGACTTCTCCATCCTGTGGATCCCATTGTAGGAGTGTTATATTTGAATTATGGGCCCTACAGTTCTTATGCACCGCATTATGACTCCACATTTGCAAATATCAGCAAGGATGATTCTGATTTAATCTATTCAACCTATGGGGAAGACTCTGATCTTCCAAGTGATTTCAGCATCCATGAGTTTTTGGCCACGTGCCAAGATTATCCGTATGTCATGGCAGATAGTTTACTGGATGTTTTAACAAAAGGAGGGCATTCCAGGACCCTACAAGAGATGGAGATGTCATTGCCTGAAGATGAAGGCCATACTAGGACACTTGACACAGCAAAAGAAATGGAGCAGATTACAGAAGTAGAGCCACCAGGGCGTTTGGACTCCAGTACTCAAGACAGGCTCATAGCGCTGAAAGCAGTAACAAATTTTGGCGTTCCAGTTGAAGTTTTTGACTCTGAAGAAGCTGAAATATTCCAGAAGAAACTTGATGAGACCACCAGATTGCTCAGGGAACTCCAGGAAGCCCAGAATGAACGTTTGAGCACCAGACCCCCTCCGAACATGATCTGTCTCTTGGGTCCCTCATACAGAGAAATGCATCTTGCTGAACAAGTGACCAATAATCTTAAAGAACTTGCACAGCAAGTAACTCCAGGTGATATCGTAAGCACGTATGGAGTTCGAAAAGCAATGGGGATTTCCATTCCTTCCCCCGTCATGGAAAACAACTTTGTGGATTTGACAGAAGACACTGAAGAACCTAAAAAGACGGATGTTGCTGAGTGTGGACCTGGTGGAAGTTGAGGCTGCCTGGTATTTGATTATATATTATGTACATACTTTTTCATTCTTAACTTAGAAATGCTTTTCAGAAGATATTAAATATTTGTAAATTGTGTTTTTAATTAAACTTTGGAACAGCGAATTTGGATGTTCCAGAGGTTGGACTTGTATTAGGTAATAAAGCTGGACCTGGGACTCGTGAGGAAGGAA

Publications

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