Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PPP2CAP1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:40937100-40939785  UCSC
Coordinates (T2T) chr1:40806468-40809153  UCSC
Coordinates (hg19) chr1:41402772-41405457  UCSC
Strand -
Parental Sequence NM_002715.4
Parental seq. overlap 1263 bp
Parental seq. overlap (%) 26.8%
Genomic Region Intergenic
Retrocopy Summary PPP2CAP1, located on chr1:40937100-40939785, is a retrocopy of the parental gene PPP2CA. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPP2CA
Full Name protein phosphatase 2 catalytic subunit alpha
Also known as NEDLBA|PP2Ac|PP2CA|PP2Calpha|RP-C
Coordinate chr5:134194332-134226073
Strand -
Gene summary This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PPP2CAP1
Bonobo Pan paniscus PPP2CAP1
Gorilla Gorilla gorilla PPP2CAP1
Orangutan Pongo abelii PPP2CAP1
Gibbon Nomascus leucogenys PPP2CAP1
Green monkey Chlorocebus sabaeus PPP2CAP1
Crab-eating macaque Macaca fascicularis PPP2CAP1
Rhesus Macaca mulatta PPP2CAP1
Baboon Papio anubis PPP2CAP1
Golden snub-nosed monkey Rhinopithecus roxellana PPP2CAP1
Marmoset Callithrix jacchus PPP2CAP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPP2CAP1
TTTTAAATTTGAACAGGATTGCCATGAATTGTATATTGACTTAATGGAAATGGGGACAGCAACAGTAACTCCAAAGTGTCAGAAAATAGTTAACATTCAAAAAATTTGTTTTCACATGGACTAAAAGCTGTGCCATATAAAAATACAAAGCTTTTTGTCACCAAGCCGTGATCACTTTAGAATAAACCAGTTCATTGTATGCTGGAGCAACATGGTGTTTGCAGTTACTTTTGCTTTCTTTGAGAGACCGCAGATAATAAGATGTAAATTCACTTTGTGAATACAATTTAACCTCCATCTAGCTATAGCTTTACTCAGCATGACTGTACATAGGGGTAGCAGAAAACAATCACTGGATCACTGGAACTTAATGAAATTAAAAAAAATAAATGCCAAGCCCTCCCCTCTACTTAAGGGTTTTGAAATCGTTCTGTTTATTTTCAGGGATACCATTTAATTTAATTATAAGACTTGCCTCCACTCAGTTTGTCGCCTTCTCAAATCTGAGCCACATGCCATTCTTCGTTATTGTCAGAACCTAGTGAGTGGTTTTGAACAGAGCTGTTTTTGCCCCTTCCTGTAAAGTGATGTTTTATTGCACAAGAGCACTGCAGAGTTTTCATAATAAACTTGCTTTACAGGCCATCTTCCTCTCACTGCCTTGGGGGATGGGCAGCTCTTCTGTCTCCATGGTGGCCTGTCGCCATCTGTAGATACACTGCATCACATCAGAACACTGAATTGCCTACAGAAAATTCCCCATGAGGGTCCAATGGGTGACTTGCTATACTCAGATCCAGATGACCATGGTGGCTGGGGTATATCTCTTTGAGGAGATGGTTACACCTTTGGGCAAGATACTCCTGAGACATTTAATCATGCCAGTGGCCTCAGGTTGGTGTCTAGAGCTCACCAGCTGGTGATGGTGGGACATAACTGGTGTCATGACTGGAATGTAGTAGCCATCTTCAGTACTCCAAACTATTGCTATCATTGTGGTAATCACACTGCAATCATGGAACTTGATAATACTCTAAAATACTCTTTTTTTGCAGTATGACCCAGCACCTCACAGAGGCAAGCCACATGTTACTCATTGTACCCCAGATTACTTCCTGTAATGAAATTTTAATTAATAGAAAATTACCAGATACAAATTACTTGTTTACAGGAGATTATATTGACAGAGGATATTATTCAATTGAAATAGTTATGCTGCTCCTAGCTGTTAAGGTTTCTTACCATGAATGCGTCACCATTCTTCCAAGGAATCATGAGAGCAGGCAGATCACACAAGTTTATCATTCCTATGAAGAGTGTTTAAGAAAACATGGAAATGCAAATGTTTAGAAATATTTTCCAGATAGAAAATTACCAGATACAGATACAGCAGCCAGCTCGGGCAGGTGGCATCATGGATGAGGTGTTCTCCAAGGAGCTGGACCAGTGGATCAAGCAGCTGAACCAGAGAAAGTAGCTATCCAAGTCCCAGGTCAAGAGCCTCTGCAAGGAGGCTAAAGAAATCCTGACAGAAGAATCCAATGCACAAGAGGTTTGGTGTCCAGTCACTGTCTCTGGAGATAAGCATGGGCAATTTCATGTTCTCATGGAACTGTTTAGAAAATTACCAGATg
>NM_002715.4
ACAGAGAGCCGAGCTCTGGAGCCTCAGCGAGCGGAGGAGGAGGCGCAGCGGCCGACGGCCGAGTACTGCGGTGAGAGCCAGCGGGCCAGCGCCAGCCTCAACAGCCGCCAGAAGTACACGAGGAACCGGCGGCGGCGTGTGCGTGTAGGCCCGTGTGCGGGCGGCGGCGCGGGAGCAGCGCGGAGCGGCAGCCGGCTGGGGCGGGTGGCATCATGGACGAGAAGGTGTTCACCAAGGAGCTGGACCAGTGGATCGAGCAGCTGAACGAGTGCAAGCAGCTGTCCGAGTCCCAGGTCAAGAGCCTCTGCGAGAAGGCTAAAGAAATCCTGACAAAAGAATCCAACGTGCAAGAGGTTCGATGTCCAGTTACTGTCTGTGGAGATGTGCATGGGCAATTTCATGATCTCATGGAACTGTTTAGAATTGGTGGCAAATCACCAGATACAAATTACTTGTTTATGGGAGATTATGTTGACAGAGGATATTATTCAGTTGAAACAGTTACACTGCTTGTAGCTCTTAAGGTTCGTTACCGTGAACGCATCACCATTCTTCGAGGGAATCATGAGAGCAGACAGATCACACAAGTTTATGGTTTCTATGATGAATGTTTAAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTACAGATCTTTTTGACTATCTTCCTCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTATAGATACACTGGATCATATCAGAGCACTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTGGTGGTTGGGGTATATCTCCTCGAGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCTCACGTTGGTGTCTAGAGCTCACCAGCTAGTGATGGAGGGATATAACTGGTGCCATGACCGGAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTTATCGTTGTGGTAACCAAGCTGCAATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCGTAGAGGCGAGCCACATGTTACTCGTCGTACCCCAGACTACTTCCTGTAATGAAATTTTAAACTTGTACAGTATTGCCATGAACCATATATCGACCTAATGGAAATGGGAAGAGCAACAGTAACTCCAAAGTGTCAGAAAATAGTTAACATTCAAAAAACTTGTTTTCACATGGACCAAAAGATGTGCCATATAAAAATACAAAGCCTCTTGTCATCAACAGCCGTGACCACTTTAGAATGAACCAGTTCATTGCATGCTGAAGCGACATTGTTGGTCAAGAAACCAGTTTCTGGCATAGCGCTATTTGTAGTTACTTTTGCTTTCTCTGAGAGACTGCAGATAATAAGATGTAAACATTAACACCTCGTGAATACAATTTAACTTCCATTTAGCTATAGCTTTACTCAGCATGACTGTAGATAAGGATAGCAGCAAACAATCATTGGAGCTTAATGAACATTTTTAAAAATAATTACCAAGGCCTCCCTTCTACTTGTGAGTTTTGAAATTGTTCTTTTTATTTTCAGGGATACCGTTTAATTTAATTATATGATTTGTCTGCACTCAGTTTATTCCCTACTCAAATCTCAGCCCCATGTTGTTCTTTGTTATTGTCAGAACCTGGTGAGTTGTTTTGAACAGAACTGTTTTTTCCCCTTCCTGTAAGACGATGTGACTGCACAAGAGCACTGCAGTGTTTTTCATAATAAACTTGTGAACTAAGAACTGAGAAGGTCAAATTTTAATTGTATCAATGGGCAAGACTGGTGCTGTTTATTAAAAAAGTTAAATCAATTGAGTAAATTTTAGAATTTGTAGACTTGTAGGTAAAATAAAAATCAAGGGCACTACATAACCTCTCTGGTAACTCCTTGACATTCTTCAGATTAACTTCAGGATTTATTTGTATTTCACATATTACAATTTGTCACATTGTTGGTGTGCACTTTGTGGGTTCTTCCTGCATATTAACTTGTTTGTAAGAAAGGAAATCTGTGCTGCTTCAGTAAGACTTAATTGTAAAACCATATAACTTGAGATTTAAGTCTTTGGGTTTTGTTTTAATAAAACAGCATGTTTTCAGGTAGAGCTTAAACTAAATGATGTGTTTACTTAGTGCAGTTTCTGGTTATGAATATTATATTGCTATGTGTATATTATATGGACTCTTTAAAATGATTGACAGATTGGCAAATTCTTAAATCTTTGTACATTGTTGAGTCATATGTTCTTAGAGTTAAATTTGTCTCAGATAAGAAAGTGTTAAAGCATTAGCCTGTGTCAAGTTCTTTGAGTGATACTAGTGAAACCAAATAGAAAACTATTGTTGGATCATGATTTAGTCTTATGTACATTCACCCGAAGACAAAAATGGTACTTAAAGTGGCAGTGTTCAACATTTAATGAGTTTTTCCCCTTTTATCCTTCGAATAGGATTAGATGTTTAAAAAAAAGTTCTTCTGTGGGAACTAATATTTGATATTTTAACCTACCAGAGTAAACAGGAACACTTAATCATACTTGTGAGTGTAGTAAATAAAAGTTTTCTTGCTTTGTGCTGTGTTGAATCTGGAACCAACAGGGAAGTTATAGCATATCCCCTTTCTAAAATGCTTGAGGAACACATACATACCGAATGTCTTTTCTGATCTAATTGATAGTATTTTTAGTGGCTTGTGGAGTTAATTTTCCAAAGCAAAAGGCCATTAGGGTTTCTAcatttcatttcatttcattcttttctttcaCAAGAAATACATTCTCTGTGTGTCTTTTTGTTGCTCTGTCACTCTATGCCCTTTCTCTCCGACTGAACAAATAGCTTATCCATGTGCAGTGGTTTTAATACCCAAACAATCTAGACACCAAGCAGCTATTTTTTCCGGTCCTGTGATATCAGAATTGACCAAGGAATACGTATATTGTAATTGACACGTGGTGGTATCTTCCAGGTACAAATTCTCTAAATTTTGTGGTTAGCAGAATGGGACTTGTGATAAGAATAGCTTGGTTTTAGCATAACTAGGGTTTAAAATAATTGTTTAATTATAGAGACTGACCGGGCTTTGGCCATCTAAACTGGAAAGTGTTAGTACCCTACCTTCTTTTGAAAATGGCTATGGTAAGGAAAATGTGTTAGTAAATTATGTATTTTCTTGAAAAATACATAATTATGGTTGGATGGGAATCACTAAGTTGGGTGTTAACTGATGTCTCAATTAGTAACATTAGGATTTTCATTAATAAACCTAAAAAGCTTTCCCTAAGAACAggcctggcacagtggctcatgcctgtaatcccagcactttgggagaccagggtgggtggatcccttgaggtcaggagttgaagagcagcctggccaacatggcaaaaccccatctctacaaaaaatatgaaaatcagccgggcttggtggcataccatagtcccagctacttgggaggctgaggtgagaggatcgcctgagcccaggagatggaggttgcagtgggctgagattgtgccactgtactccagtctgggtgacagagccagaccctgtctcaaaaataaaGAGGATTCTGAGTTTGTATAGTGAGGGCTTGCAGAAATTTTGAAACTTATTTTGTAAGTTTACAATGAATTTGTACATGATGTGCTCATGTCTTGGGTTGAGTATCCTAGACATGATTTTTTCATTTGCTGCATATTAAACATTTGTTGGTTGTAGTCGGTATTTCTTAAATAGAAGTTTGTCAATATTAGATTAGTTTCAAGAAGGACTTAGCTCAGGAAAAGGATAGTTATTTCTGTGGTTCTCAGCTTTGATGcctacagagattctgatttaaattgctggaggagggcccaggcatacattttttaagtttcccaagtgattctaatttacatctagggttaaaaacAgccaggcgcggtggctcatgcctgtaatcccagcacttggggaggccggggtgggtggatcacctgatgtcaggagatcgagaccagcctggccagcgtggtgaaaccccatctctattaaaaatacaaaactgaccggtgtggtggcaggagcctgtaatcccagctacttgggaggctgaggcaggagaatcacttgaactcaggaggaggaggttacagtgagcccagatcgtgccattgcactccagcctgggcaaaaagagcaaaactccatctcaaaaaacaaaaaCACCTCACTGCTGTTTCCTAAGTACATACTTAAGAAAATTGGGATACATGGTGGTGGTTCATGGATGTTGATAAGGAATTAAAATGTACCGTGCGACTCTCTGTTTCAGTGGTGACTTTTACCTGTTTAGTATAAATATTCCTTTGCTTCCAACCATAAATGTGTTCTTAGAAATGGGCCTATAGTTTAGTAACCTATAGTTTGGTAATAGGCTTGTTTGTTTTCAGATGGATTTTGGTTCTGTGAGCTAAAGCTATTTTGCATTAAAGCCTTCGTCCTCACA

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