Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ELK2BP
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:105545422-105547654  UCSC
Coordinates (T2T) chr14:99796885-99799117  UCSC
Coordinates (hg19) chr14:106011759-106013991  UCSC
Strand -
Parental Sequence NM_001114123.3
Parental seq. overlap 1134 bp
Parental seq. overlap (%) 29.3%
Genomic Region Intergenic
Retrocopy Summary ELK2BP, located on chr14:105545422-105547654, is a retrocopy of the parental gene ELK1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ELK1
Full Name ETS transcription factor ELK1
Also known as -
Coordinate chrX:47635520-47650604
Strand -
Gene summary This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ELK1P1
Bonobo Pan paniscus ELK1P1
Baboon Papio anubis ELK1P1
Golden snub-nosed monkey Rhinopithecus roxellana ELK1P1
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ELK2BP
CCTTCTGGGGTCCCTCCATCCGTGCTCTCTCAAGGAGAAACACAGTTCAACTGAAAGACTCATGCTCTGATTGTGGTGGGGTGGGGATCCTTGGGAAGGATTTCTCCCAGGAGTGACTCTCATTAACTCCTCCACAGAAAACACTCAGCTTCCACAGCTTCTCTCTTTTCTCTCTTTTCTGTCCGTCCCCCAGTGGCTGCCCTGACACGTCTCCTACTTCAATGGTAGGGGCGGTTTATTTATTTATTTTTTGAAGGCCACTGGGAAGCGCCTGACCTAACCTATTAGGGTGGTCAGGACGTCTCCCCCACCTCCCCGCTTTTTTCCCCAAGACAGGACAATCGGGGTCTGGCTTGAGAACGACCTTTCTTTCTTCATTCCTCGGCCTGCCCGTGGGGAGATGAGGGAGCCCTGTGTCCATTTTAGGATGTGAGTAGAAGTTAGTTTCGTTTTATTATTCCTGGCCATACTCGGGGTCCAGGAAGAATTTGTACCATTTAATGGGTTGGGAGTCTTGGCCAAGGCAGAATCACACCCTTGGAATAGAAATTTCCACCTCCTCAACCTTTCTCTCAGACAGCTTATCCTTTTTTAACCAACTTTTTGGCCAGGGAGGAATGTCCCTTTGTTCTTCTTCCCCCTGAGAAGCCATTCCTTTGTCTGCCAAACTCCCTGGGGTCCTGCCTGTTTCCTCCCATGGAGGGGTTTTGTGGGGGTGGTTCCTGTCTGGGGGGCCCCTCCAGCCAGTACTCCAGGTCTCCCTGTCTCTCCCCTGCTGCCATTTTGATAGTATAATCTATTTTTAAATGGGGCTTTTCAATAGAGGAGAGGGAGTCATCTCTTCCTATATTTGGTGGGGTGGATGTGAAGGAAGGGATGTGGGGGGCAATCTTCCTGCCGCCTCCCCCTCAGGGGTTTATTTTTGATAACAAATGTGTATTTTCAGTTCCCTCCCTCCCAGCCCCCCAATTTCCTGCAGGTAGGTACAAAGGACACTTTCAATGTCCCTGGAGTTGGGAGGGAGGAATGGGGGACATAAAGCCTGTCCTGTCTCTATTCTAGGCAGGAAGAGTGGGTTCAAAAGACTCCTGGGCTTCCCTGTCAGCCCTGGCCCAGCCCAGGCCTTGGGACCTGGGGGTTGGTGATTTGGGGGACGGTGCCACTATGACGAGAACATCATCCGCAAGGTGAGCGGCCAGAAGTTGGTCTACAAGTTTGTGTCCTATCCTGAGGTCGCAGGGTGCTCCACTGAGTGAGGACTGCCCGCCCCACCCAGAGGTGTCGGTTACTTCACCATGGCAGTTGTGGCCCCTGCTGCTGCACATGCCGCCCCAGGGGGCACTGCCTCAGGAAAGCCAGGCACACCCAAGGGTGCAGGAATGGCAGGCCCTGGCGGTTTGGCGCGCAACAGCCGGAACAAGTACATGCGCTCGGGCCTCTGTTCCACCTTCACATCCAGTCTCTGCAGCCGCAGCCACCCCCTCAGCCTCGGCCTGCTGCGGTGCTCCCCAACGCAGCTCCTGCAGTCCAAGCCCCTGGGAGGCCTGCCTGGAGGCTGAGGAAGCCGGCTTCCCTCTGCAGGTCATCCTGACCCCGCCCGAGGCCCCAAACCTGAAATTGGAAGAGCCGAATGTGGAGCCGGGCTTGCGCCGCCCTTTGCCCCCGGAAGTGGAAGTGGAAGGGCCCGAGGAAGAGCTGGAATTCGCGGGGGAGAGAGGGTTCGTGCCAGAAACCGCCAAGGCCGAGCCTGAAGTCCCTCCACAGGAGGGCGTGCCAGCGTGGCTGCCGAGGTCCTTATGGACACCGCAGGGCAGGCGGGCGGCCACGCGGCTTCCAGCCCTCAGATCTCCCAGCCGCAGAAGGGCCGGAAGCCCCGGGACCTAGAGCTTCCACTCAGCCCGAGCCTGCTAGGTGCGCCGGGAGCCGAACGGACCCCAGGATCGGGAACTGGCTCCGGCCTCCAGGCGCCGAGGCCGGCGCTGACCCTGTCCCTGCTTCCTACGCACACGTTGACCCCGGCGCTGCTGACACCCAGCTCGCTGCCTCCCAGCGTTCACTTCCGGAGCAGCCTGAGTCCCGCTGCGCCCCGCAGCCCGGCCAAGCTCTCCTGCCAGCTTCCGTCCAGTGGCGGCGCCCAGGTGCACATCCCTTCCATCGGCGTGGCTGGCCTCTCGACCCCCGCGGTGCTCTCGCCAGGGCCCCAGAGGCCATGa
>NM_001114123.3
CTAGGTGCTgccgccgccaccgccaccaccacctccaccgccgccTCGGAACCCAGGCCTGGGGGGCGGTGGGGCCGCGTATGGAGCCCCCGCCCCCCGGAGCTGCCAACATTGCCAACGCCACCGCCACGCTACACACAGCCTCAACTTTCAGGAGACCCGTCCGTGGCCTTATTTATTCCACCCTTCCTGTACATCGTAGCGAATCAATCCGTGGCGCCGCACTCCTCCGCATCCCTCTTTAACAGTACCCCTGGGATGGCGTGAGCACTCCCCCAGCGATGGACCCATCTGTGACGCTGTGGCAGTTTCTGCTGCAGCTGCTGAGAGAGCAAGGCAATGGCCACATCATCTCCTGGACTTCACGGGATGGTGGTGAATTCAAGCTGGTGGATGCAGAGGAGGTGGCCCGGCTGTGGGGGCTACGCAAGAACAAGACCAACATGAATTACGACAAGCTCAGCCGGGCCTTGCGGTACTACTATGACAAGAACATCATCCGCAAGGTGAGCGGCCAGAAGTTCGTCTACAAGTTTGTGTCCTACCCTGAGGTCGCAGGGTGCTCCACTGAGGACTGCCCGCCCCAGCCAGAGGTGTCTGTTACCTCCACCATGCCAAATGTGGCCCCTGCTGCTATACATGCCGCCCCAGGGGACACTGTCTCTGGAAAGCCAGGCACACCCAAGGGTGCAGGAATGGCAGGCCCAGGCGGTTTGGCACGCAGCAGCCGGAACGAGTACATGCGCTCGGGCCTCTATTCCACCTTCACCATCCAGTCTCTGCAGCCGCAGCCACCCCCTCATCCTCGGCCTGCTGTGGTGCTCCCCAGTGCAGCTCCTGCAGGGGCAGCAGCGCCCCCCTCGGGGAGCAGGAGCACCAGTCCAAGCCCCTTGGAGGCCTGTCTGGAGGCTGAAGAGGCCGGCTTGCCTCTGCAGGTCATCCTGACCCCGCCCGAGGCCCCAAACCTGAAATCGGAAGAGCTTAATGTGGAGCCGGGTTTGGGCCGGGCTTTGCCCCCAGAAGTGAAAGTAGAAGGGCCCAAGGAAGAGTTGGAAGTTGCGGGGGAGAGAGGGTTTGTGCCAGAAACCACCAAGGCCGAGCCAGAAGTCCCTCCACAGGAGGGCGTGCCAGCCCGGCTGCCCGCGGTTGTTATGGACACCGCAGGGCAGGCGGGCGGCCATGCGGCTTCCAGCCCTGAGATCTCCCAGCCGCAGAAGGGCCGGAAGCCCCGGGACCTAGAGCTTCCACTCAGCCCGAGCCTGCTAGGTGGGCCGGGACCCGAACGGACCCCAGGATCGGGAAGTGGCTCCGGCCTCCAGGCTCCGGGGCCGGCGCTGACCCCATCCCTGCTTCCTACGCATACATTGACCCCGGTGCTGCTGACACCCAGCTCGCTGCCTCCTAGCATTCACTTCTGGAGCACCCTGAGTCCCATTGCGCCCCGTAGCCCGGCCAAGCTCTCCTTCCAGTTTCCATCCAGTGGCAGCGCCCAGGTGCACATCCCTTCTATCAGCGTGGATGGCCTCTCGACCCCCGTGGTGCTCTCCCCAGGGCCCCAGAAGCCATGactactaccaccaccaccaccaccCCTTCTGGGGTCACTCCATCCATGCTCTCTCCAGCCAGCCATCTCAAGGAGAAACATAGTTCAACTGAAAGACTCATGCTCTGATTGTGGTGGGGTGGGGATCCTTGGGAAGAATTACTCCCAAGAGTAACTCTCATTATCTCCTCCACAGAAAACACACAGCTTCCACAACTTCTCTGTTTTCTGTCAGTCCCCCAGTGGCCGCCCTTACACGTCTCCTACTTCAATGGTAGGGGCGGTTTATTTATTTATTTTTTGAAGGCCACTGGGAGGAGCCTGACCTAACCTTTTAGGGTGGTTAGGACATCTCCCCCACCTCCCCACTTTTTTCCCCAAGACAAGACAATCGAGGTCTGGCTTGAGAACGACCTTTCTTTCTTTATTTCTCAGCCTGCCCTTGGGGAGATGAGGGAGCCCTGTCTGCGTTTTTGGATGTGAGTAGAAGAGTTAGTTTGTTTTGTTTTATTATTCCTGGCCATACTCAGGGGTCCAGGAAGAATTTGTACCATTTAATGGGTTGGGAGTCTTGGCCAAGGAAGAATCACACCCTTGGAATAGAAATTTCCACCTCCCCAACCTTTCTCTCAGACAGCTTATCCTTTTCAACCAACTTTTTGGCCAGGGAGGAATGTCCCTTTTGTTCTTCCCCCTGAGAAGCCATTCCTTTGTCTGCCAACCTCCCTGGGGTCCTGCCTGTTTCCTCCCAATGGAGGGTTTTTTTGGGGGGTGGTCCCCGTCTGGGGGGCCCCTCCAGCCAGTACTCCAGGTCTCCCTGTCTCTCCCCCGCTGCCATTTTGATAGTATAATCTATTTTTAAATGGGGCTTTTCAATAGGGGAGAGGGAGTCATCTCTTCCTATATTTGGTGGGGTGGGTGGGAAGGAAGGGATTTGGGGGGGAATCTTCCTGCCGCCTCCCCCACTCCAAGTGTTTATTTTTGATACCAAACATGAATTTTCAGTTCCCTCCCTCCCAGCCCCCCAATTTCCTGCGGGCGGGTACAAAGGACCCTTTCAATGTCCCTGGAGTTGGGAGGGAGGAATGGGGGACATAAAGCCTGTCCTGTCTCTATTCTAGGCAAGAGAGAGTGGGTTCAAAAGACTCCTGGGCTCACCTGTTAGCGCTGGCCCAGCCCAGGCCTTGGGACCTGGGGGTTGGTGATTTGGGGGACAGTGCTACACTCGTCTCCACTGTTTGTTTTACTTCCCCAAAATGGACCTTTTTTTTTTCTAAAGAGTCCCAGAGAATGGGGAATTGTTCCTGTAAATATATATTTTTCAAAGTGA

Publications

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