RCPedia: Rtcs

Summary

Retrocopy Name	ARHGAP42P4	Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr14:19688173-19692856 UCSC
Coordinates (T2T)	chr14:13888010-13892693 UCSC
Coordinates (hg19)	chr14:20156332-20161015 UCSC
Strand	+
Parental Sequence	NM_001367945.1
Parental seq. overlap	3968 bp
Parental seq. overlap (%)	46%
Genomic Region	Intergenic
Retrocopy Summary	ARHGAP42P4, located on chr14:19688173-19692856, is a retrocopy of the parental gene ARHGAP42. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	ARHGAP42
Full Name	Rho GTPase activating protein 42
Also known as	AD031\|GRAF3\|TMEM133
Coordinate	chr11:100687288-100993941
Strand	+
Gene summary	This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	Without Homology
Bonobo	Pan paniscus	Without Homology
Gorilla	Gorilla gorilla	Without Homology
Orangutan	Pongo abelii	Without Homology
Gibbon	Nomascus leucogenys	Without Homology
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Rhesus	Macaca mulatta	Without Homology
Baboon	Papio anubis	Without Homology
Golden snub-nosed monkey	Rhinopithecus roxellana	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>ARHGAP42P4
GCCCCAGCGCCCGCCGCGGCCTCCAGCTGCCCCCGCCCTGACCACTGGCCCGGACGTGCCAGCGGCCGCCGCTGGCAGCGCCTGTGCCATGGGGCTGCCCACTCTGGAGTTCAGTGATTACTACTTGGACAGCCCGGATTTTAGGGAGCGCTTGCAGTGTCACCAGATTGAGCTGGAGCGAACCAACAAGTTCATCAAGGAGCTCATTAAGGACGGCTCTCTGCTCACTGGGGCGTTGAGGACAGGTAATGTTGATTGCCTGCCCAGTTCCCTTGCCCTTTCATCCTTTCCAAAGGAACCCTGAGTTCCTTCAGTAACACACCTCTACCCAGGTTGGAGATCTGTCTATGGCAGTGCAGAAATTTTCCCAGTCATTACAAGATTTCCAATTTGAATGTATTGGTGATGTTGAAACAGATGATGAAATTAGTATTGGTCAGTCACTAAAATAATTTGCAAGACTACTCATTGCAGTAGAAGAAAAGCGAAGACTGATCCAAAACGCTAATGATGTATTAATTGCACCACTTGAGAAACTTCAAAAAGAACAGATAGGTGCAGCAAAAGGTGGAAAGAAGTTTGACAAAGAGAGTGAAAAATATTACTCTATCCTTGAAGAGCATTTAAATTTATCTGCAAAGAAAAAGGAGTCTCATTTGCAAGAGGCAGATACACAAATTGATTGAGCACATCAGAACTTCTATGAAGCATCATCAGAATGTCTTTAAAaTAAAAGAAAAAAGAATATGTCTTTAAAATTCAAGAGGTTCAAGAAAAACAGAAGTTTGAATTTGTTGAACTGCTTTTGTCATTTCTTCAGGATTTATTTACTTTTTTACCCCGAGGGATATGAACTTGCCCAGGAATTTGCACCAAATAAGCAACAGCTGCAGTTCGACTTGCAGAATACAAGGAATAATTTTGAAAGTACTTGACAAGAGGTAGAGGGGTTGATGCAAAGGGTGAAATCTGCAAGGCTATCTGCATGTCCAGGAGAAATGACCACTTGGTTTTACATGGATTAAACAGCCTTGTTACTAGCTCACCGGAAATGTTCAAAATCTTGTATCCAACAAAAGACAGATTCAATTGACAAACAATTCTGCTTCGACATACAAGTAGTTGAAAGCCATGGGATCATCACATTACAGGCCTTCTCAGAAGCTAATAGGAAACTCTGGCTTGAAGCCACGGATGGGAAGGAACCACTTTATACTCTGCCTGACATTATAAGCAAGAAAGAAGAAATGTATTTGAATGAAGCAGGGTTCAATTTTGTGAGAAACTGCATTCAAGCTGTGGAAACCAGTGGTATCACCATTTTAGGCCTCTACTGAATAGGAGGAGTGAACTCCAAAGTTCAAAAACTCGTGAATATCATATTTTCTCCTAAATCCCCTCCTGATATTGATATTGAACTGTGGGACAATAAGACAATAATGAGTGGGCTGAAAAACTACCTCAGGTGCTTTGCAGCACCTCTGATAACTTACAAGTTACACAAAGATTTGTATCACTGCTGTTAAATCTGATGACCAAAACTACAGGGTGGAGGCTGTACATGCATTGGTGTGCACATTGCCAGAGAAAAACAGAGAGATGCTGGACATCTTAATAAAACATCTGGTCAAAGTATCACTGCACAGCCAACAAAATCTCATGACTGTCTAAAATCTTGGTGTCATATTTGGCCCAACTCTAATGAGAGCACAAGAATAAACTGTGGCTGCTATGGTGAATATTAAATTTCAGAATATTGTGTAGAAATTCTGATAGAGCACAGTGAAACAATTTTTCATACTGCTCCAGACCCAAGCATTCCTCTTCCTCAGCCTCAGTCTCGATCTGGATCCCAAAGGACAGCCTCAGTCTCGATCTGGATCCCAAAGGACATGAGCAATCTGCCTCTCTACAGGCTCTAGGAAGCCCAGAGGGATGTGTACTCCATGCCTGGCTGAACTTGATAGTGATTCCTATAGCAGCAGCACAGACAGCACCCCCATGGGGAGCATCAAGTCACTCTCTTCTCTTTCCTCAGAACAAAATAGCACTACAAAGTCAGCTTTCTGCCAGCCCAGGGAGAAATCTGGAGGGATTCCTTGGATTGCAACCCAATCTTCCAATGGACAGAAAAGCCTTGGTCTCTGGACAACTAATCCTGAATCAAGTTCTAGAGAAGATGCAACCAAGACAGATGCAGAATCAGATTGCCAGAGTGTTGCTTCGGTCACTAGCCCAGGGGATGTTTCCCCACCCATAGACCTAGTCAAGAAAGGGCCTTATGGGCTTTCAGGACTGAAAAGAGCTTCTGCTTCTTCTCTCAGATCCATCTCTGCAGCTGAAGGAAACATTAGCTACAGTGGATCTATTCAAAGCTTAACTTCTGTAGGTTCCAAGGAGACACCCAAAGCTTCAAACCCAGACCTGCCTCCAAAAATGTGCAGGAGGTTAAGACTAGACACCACCTCAAGCAATGGCTATCAGCGTCCTGGCTCAGTAGTGGCAGCAAAAGCTCAACTGTTTGAAAATGTTGGTTCACCTAAGCCAGTTTCTTCTGGGCACCAAGCCAAAGCCATGTACTCCTATAAAGGAGAGCACAGCGTGAGCTTTCCTTCCCACAAAGAGCGATATTTTCCAGTGTGGACCCATCAGTGGAACCAGGATGGTTAAAGGCAGCTTATGAAGGCAAAACGGGACTAGTTGCAGAAAATTATGTTGTCTTCCTCTACTACTATTTAGTGGATGGCAGTATCTTCATGGTATCCGGTAACAAATAATAAGTGCTATGATTTTATCTGACACAGATACAAGGGGATCAGCCCACTAAGTGAAAACAGTCAATTTCTATCAAGTTCTTCACCAGCAGACTATGTAGCTCCTTATTAATGGAAAAAAAGGTTTAAATGGTTGGCCATTCTTTTTTGGTTGGTTTCTTATTTTAAAATTTCTTGCTTCTGAAAAATTTATTTTTGGATAATACGTAACTCTCCAGAATGTCTCTTCCATAGCAATTGTAGAGTTTCAAATACTTTATTAAGTACTATATCCCATAAACTTGGAAACCAGAAATCTGCTGTATGGATTTTGAGATGTGTCCTTTACTGCCTGGCATTCTCTAAGGATCTCTGAAAGTGCTACTTAAAAATGTTACTGAAAAGCTGGTTACCTGCCCTTTGAGTGCCACAGTCCTGACCTGCTTGTTCTTGACACCTTACATATTACTTCGGAGTTCCCCACTGTGCAGACTCTCAGGTATTAACTGTATAAAACTCTTTACATGCTATTATAATCTGCAATCTCAATCTCTTCTACTTTAAATTAATGTTTCTAGAATAGGTTAAATACACATATACACACACAACTATGCCTGAGAAAAGTTATGCTTTTACAAATAAAAAGAATAGATTAGCATTAACAAGTAGGGTGAATAACAGTAGGCAGAGTCAGAATCAGAAATAAATACCAGTGAATCAAAATAAAAGAATGAAAAATATTCTGTATTAAAAATTGTCAATGTAATGTAAAAGTCTGATAAAAGATTATTCTTTTTCTTTTACCTCTGACTGTTGACCTCTGTACACTGTAATAAGGTGTTGCTGGATGGAACTTCTTGATCTAGGTCCTTGGTGACCTTAGTAGTAATAACAGCATTGCTGGCACCCTAATTACCCTCTGCTGAAACAGAAGGTAGTTTATCAATGTACCAATCCCTTAGTCTATACTTGGTTTAAACACGCTTGCCATCATCTGGTATCCTGCTAGATTAGAACCTCTTAAAAGCAAATTGGTTTTCTTTCAAAGACCAACCTGACTCCAAAGACAGATACGGAATCCTGCTTCTTCTGCTGCATAAAGAAATCTCAACCTTCATTTTACTTGAACACAGACCGAAGTGTTCCTACTTCTGCGTTGTCTGTGAGCTAGTTCTACGGATGTTCCACTCAGATTTAAAGCTTTTTATTGCACAGGACGTGGATATGAAGCCTAACTCTTGTATCTGATGGCAAGGCATATGTTGTAGCCACAGTACTGGCTATGGTCCCTTTGCTGAAAGAAGCTACAGAAGCACTGATTCAAGCTGTGTTTGTGCTAGAAGTTTTAATCTTGTAGATTTGTGAGGATGGCTCTTTTTCCTTCATAATAGATTACATGTACAAGCAAGTCAGGGCCATATACTGGAGACAGGCTAAAGCTGCTTTTCTCTTAAAGAAAGTTTCCTACAGATAAGGTATTTATGAGCATTGAGAAAGTCAGGACGTGTACTCTAAATCACACAGAGTGTTAATTCCACAGGAAGGCAATGCCAGACATTGGAAGAGGATCACATTCAACTTCTAATAGTAGTTCAATAACAAAACCTTAGCTTTTCAGAAAAAAATGTGAAGA

>NM_001367945.1
ACAACGCCGACGACTGTCAAGAGAGTTGGGGAGTGGAACTGCCGGAAGTGTCTGCGCGCCGTGAGAGAAACTTTCCTGCTCCGGCCGCGGCCCGGAGCCTCGCCGCCCCCGCGTTCCGAACGACGATGCGTCCAGATGACAACAACCTGAGGGGACTcgcgcctcggcccgccgcccgcgcctgcgctcgcCTAGCCTCGGGGGAGGAAGACTGAGCCCGGCGCAGGCGGCGCGGCGCTCGGGGCCCGTTTCCTCCGCGCAATCAGTCCCCTCGCGTCCCGGCGCCTTCCCCGCGATCGCGCGACCCCAGCGCCCGCCGCGGCCGCCGGCTGCCCCCGCCCTGACCTCCGGCCCGGACGTGTCCGCGGCCGCCGCTGGCAGCGCCTGTGCCATGGGGCTGCCCACTCTGGAGTTCAGCGATTCCTACTTGGACAGCCCAGATTTCAGGGAGCGCTTGCAGTGTCACGAGATTGAGCTGGAGCGAACCAACAAGTTCATCAAGGAGCTCATTAAGGACGGCTCTCTGCTCATTGGGGCGTTGAGGAATCTGTCTATGGCAGTGCAGAAATTTTCCCAGTCATTGCAAGATTTCCAGTTTGAATGTATTGGTGATGCTGAAACAGATGATGAAATTAGTATTGCTCAGTCACTAAAAGAATTTGCAAGACTACTCATTGCAGTAGAAGAAGAAAGGCGAAGACTGGCAATGTTTTAAGAGGTTTTGCTGCCAGCCCCCAAAAAGCAGGCGATAAAAATGAGAATAGCCTGACATTTCCATGGCAAACTTCTTGGTGTTGTTGTAACTGGAGCTTGGATGAGGATGAGACAAGCCACATTGGAGAATGTGCTTCCCTTTCCAGCTGTCCGGCTGTCTGGGGAGATGTAAGAAAAGGTATCTGACTTAGCCTTGGAGGAAGGCTTACAATCTAGTTAAATAGAAAAGCCTATTATAAACCTGAAGCATTTCAAAAACATGGCCTGGTTGAATTGTGATGAGCTCCCTATCCAAAACGCTAACGATGTATTAATTGCACCACTTGAGAAATTTCGAAAAGAACAGATAGGTGCAGCAAAAGATGGAAAGAAGAAGTTTGACAAAGAGAGTGAAAAATATTACTCTATCCTTGAAAAGCATTTAAATTTGTCCGCAAAGAAAAAGGAGTCTCATTTACAAGAGGCAGATACACAAATTGACCGAGAACATCAGAACTTCTATGAAGCATCATTAGAATATGTCTTTAAAATTCAAGAGGTCCAAGAAAAAAAGAAGTTTGAATTTGTTGAACCGCTTTTGTCATTTCTTCAGGGCTTATTTACTTTTTACCATGAGGGATATGAACTTGCCCAGGAATTTGCACCGTATAAGCAACAGCTGCAGTTCAACTTGCAGAATACAAGGAATAATTTTGAAAGTACTCGACAAGAGGTAGAGCGGTTGATGCAAAGGATGAAATCTGCTAACCAGGACTACAGACCACCCAGCCAGTGGACGATGGAAGGCTATCTGTATGTCCAGGAGAAACGACCGCTTGGTTTTACATGGATTAAACATTATTGTACATATGATAAGGGAAGTAAAACATTTACAATGAGTGTTTCAGAAATGAAATCCAGTGGGAAAATGAATGGCCTTGTTACTAGCTCACCGGAAATGTTTAAATTAAAATCTTGTATCCGACGAAAGACAGATTCAATTGACAAACGATTCTGCTTTGACATAGAAGTAGTTGAAAGGCATGGGATCATCACGTTACAGGCCTTCTCAGAAGCTAATAGGAAACTCTGGCTTGAAGCCATGGATGGGAAGGAACCGATTTATACTCTGCCTGCCATTATAAGCAAGAAAGAAGAAATGTATTTGAATGAAGCAGGGTTCAACTTTGTGAGAAAATGCATTCAAGCTGTGGAAACAAGAGGTATCACCATTTTAGGACTCTACCGAATAGGAGGAGTGAACTCCAAAGTTCAAAAACTCATGAATACCACATTTTCTCCTAAATCCCCTCCTGATATTGATATTGATATTGAACTGTGGGACAATAAGACGATAACAAGTGGGCTGAAAAACTACCTCAGGTGCCTTGCAGAACCACTGATGACTTACAAGTTGCACAAAGATTTTATCATTGCTGTTAAATCTGATGATCAAAACTACAGGGTGGAGGCTGTACATGCATTGGTGCACAAATTGCCGGAGAAAAACAGAGAGATGCTGGACATCTTAATAAAGCATCTGGTCAAAGTATCACTACACAGCCAACAAAATCTCATGACTGTCTCAAATCTTGGTGTCATATTTGGCCCAACTCTAATGAGAGCACAGGAAGAAACTGTGGCTGCTATGATGAATATTAAATTTCAGAATATTGTGGTAGAAATTCTGATAGAGCACTATGAAAAGATTTTTCATACTGCTCCAGACCCAAGCATTCCTCTTCCTCAGCCTCAGTCTCGATCTGGATCCCGAAGGACACGAGCAATCTGCCTCTCTACAGGGTCTAGGAAGCCCAGAGGGAGGTATACTCCATGCCTGGCCGAACCTGATAGTGACTCCTATAGCAGCAGCCCAGACAGCACACCTATGGGGAGCATTGAGTCACTCTCTTCTCATTCCTCTGAACAAAATAGCACTACAAAGTCAGCTTCCTGCCAGCCCAGGGAGAAATCTGGAGGGATTCCTTGGATTGCAACCCCATCATCTTCCAATGGACAGAAAAGCCTTGGTCTGTGGACAACTAGTCCTGAATCAAGTTCCAGAGAAGATGCAACCAAGACAGATGCAGAATCAGACTGCCAGAGTGTTGCTTCAGTCACTAGCCCAGGAGACGTTTCCCCACCCATAGACCTAGTCAAGAAAGAGCCTTATGGGCTTTCAGGACTGAAAAGAGCTTCTGCTTCTTCTCTCAGATCCATCTCTGCAGCTGAAGGAAACAAGAGCTACAGTGGATCTATTCAAAGCTTAACTTCTGTAGGTTCCAAGGAGACACCCAAAGCTTCACCAAACCCAGACCTGCCTCCGAAAATGTGCAGGAGATTAAGACTAGACACTGCCTCAAGCAATGGCTATCAGCGGCCTGGCTCAGTAGTGGCAGCAAAAGCTCAACTGTTTGAAAATGTTGGTTCACCTAAACCAGTTTCTTCTGGGCGCCAAGCCAAAGCCATGTACTCCTGTAAAGCAGAGCACAGTCATGAGCTTTCCTTCCCACAAGGAGCAATATTTTCTAATGTGTACCCATCAGTGGAACCAGGATGGTTAAAGGCAACTTATGAAGGCAAAACAGGACTAGTTCCAGAAAATTATGTTGTCTTCCTCTAATACTATTTAGTGGATGGCAGTATCTTCATGGTATCCATGGTAACGAATAAATGCTATGATTTTATCTGACACAGATACACGGGGATCAGCCCACTAAGTGAAAACAGTCAATTTCTATCAAGTTCTTCACCAGCAGACTATGTAGCTCCTTATTAATGGAAAAAAAGATTTAAATTGTTGGCCATTCTTTTTTGGTTGGTTTCTTATTTTAAAATATCTTACTTGTGAAAAATGTGTTTTTGGATAATATGTAACTCTCCACAATGTCGCTTCCGTAGCAATTGTAGAGTTTCAAATACTGTGTTAAATACTGTATCCCAGAAATTTGGAAACCAGAAATCTGCTATATGGATTTTGAGATCTGTCCTTTACTGCCTGGCATTCTCTGAGGATCTCTGAAATTGTTACTTAAAAATGTAATTTAAATTGTTCATTTATTGTTTTTTTTTTCTTAGAAATATACTGCTTTTATATATGATTGTTTTGCTGGTCCTAAACATTTCAAGGATGTAAGTCTTTGTTTTAATATAACTTTATTTGTTTTCCAAGTAGATGATAATATTCAAAAGCAATAATGTATATGATATCTATAAAGGAAGCAAAATTAAGTCATACACTGATTCCACTGTAAACAATCTGTCCAGAATTCCAGACACCTtcagcaaactttttctgtaaaggcctgatagcaaatattttTGTGGTGGGTTGAATTTGGCTTATGGGTTATAGTTTGCTGACACCTAGTTTAGAGGGTGTGTAAAACTATCTTCATAACTTTGAGATTTTTATAAAATTTTACATGAAAATATACTGATAAATTATATGCACATATTTTCTACCAGTAGCATTATAGTGGCATCATAGAAGAATATTTACCAATGATGGGGAAACTGTAAAACTACAGTATCAAGGCATACAACTTAAATTCCACTTGGAAGATTGTAAAGTGTCAAAGTATTTTAATGATAATTTAATTTGGGCTTTTGAAATGTTCTTCTACAAATGAAAAAGATGTTTAAAAACGTTACAAGGGAAGCTATGCCTTCTGAAGTCTATCCTTAGTTGAAACAGAAAATAAACACAAAGGTACAAGATCCTTAAATTATTTTGAACCACAGAGGTTGAAATTGTTTTGTGATCTTCAGCAGAAATAAAATCTGTACATGATTTTCTTTTATGCCTTTTAGTTTACAGTCTTTATTAGCAATTTCAGTGAATTTGTAGAGCATAGTAATAGGTATTTACTGTCCACTTATATATATCAGCATCTGGTCATGCACGAACCATTAATTCTATATTTCTATTTCAATAATTCTAATATATTATTTCTATAAATGTAATATCTGTATGTGGCAAAGAGCCTTTCTTCTCAAGATCCTGAAAAGCTGGTTACCTGCCCTTTGAGTGCCACAGTCCTGAACTGCTTGTTCTTGACATCTTGCATATTACTTCAGAGTTCCCCACTGTGCAGACTCTCAGGTATTAACTGTAAAAAACTCTTTACATGCCATTATTATCTGTAATCTCTATCTCTTCTACTTTAAATTAATGTTTCTAGAATTAATAGGTTAAATACACATACACACACACAACTATGCCTCAGAAAAGTTAGGCTTTTACAAATAAAAAGAATAAGATTAGAATTAACAAGTAGAGAGAATAACGGTAGGCAGAGTCAGAATCAGGAATAAATATCAGTGAATCAAAAGAATGAAAAATATTATGTAATAAAAATTAGCAATGTAATGTAAACGTTTGATAAAAGAGTATCTTTTTCTTTTATCTCTTACTGTTGACCTCTGTGCACTGTAATAAGGTGTGTTGCTGGATCTTCTTGGTCGAGGTCCTTGGTGACCTTAGTAGTAATAACAGCATTGCTGACACCCTAATTGCCCTCTGCTGGAACAGAAGGTAGTTTTCCAGTGTACCAGTCCCTTAGTCTATACAGCACCCTTGGTTTAAGCACACTTGCCATCATCTGGTATCCTGCTAGACTAGAATCTCTTAAAAGCAAATTGGTTTTCTTTCAAAGACCAACTTGACTCCAAAGAGAGATTCAGAATCCTACTTCTCCTGCTGCTGCATAAAGAATCTCAACCTTCATTTTATTTGAACACGGACCAAAGTGTTCCTGCTTCTGAGTTGTCTGTAAGCTAATTCTGCAGATGTTCCATTCAGATTTAAAGCTTTTTTACTGCATAGGATGTGGATAGGAAGCCTAACTATTGTATCTGATGGCAAGGCATATGTTGCAGCCACAGTACTGGCTATGGTCCCTTTGCTGAAACAAGCTACAGAAGCACTGATTCAAGTTGTGCTTGTGCTTGAACTTTTAATCTTCTAGATTTGTGAGGATGGCTCTTTTTCCTTCATAATGGATTACAATGTAAGCAAGTCATGGCCATATACTGGAGACGGGCTAAAGCTGCTTTTCCCTTAAAGTAAGTTTCCTACAGATAAGGTATTTATGAGCACTGAGAAAGTCAGGACATGTACTCTAAATCACACAGAATGTTAATTCCACAGGAAGGCAATGCCAGACATTGAAAGAGGATCACATTCAACTTTTAATAGTAGTTCAATAACAAAACCTTAGCTTTTCAGGAACAATGTGAAGATACATTAGAATTGCCACATCCATATCTTCAAAACACGCAACCTCTGCACCCTAATAACTGCTTACGGTATAATCAGTATGATGATGAGATTGAGGGGGTCTAAATTTAAGTTCCTTATCTCCTGAGTTATGTGAAAATATCCCTCAGTACAAAACATTTGTGTGTTTCACAGATGACTCTCTTGTTTTGCCGTAATGCTACCAAGTTTATGGAAACTAGTCAACTGAAGGATTTTTCTGTTGTGTTATGTGTAAATGTCTGAACAGTAAAATCATCTGTGTATTCCTGTAACATTCACGAAGTATGAGGAAGTGGGTTTCTCCTTGTTTGATGTGAGTGGTTTTGCTTGTTGCATGGGTTCCCTGTGCTTTGTAACTTGCATGAACACAACCAGGTTTCTCAACAATGATTTGTCTGCTGACTCTTTTCAGAGATAGTGAAGGAAAAAAAATGTATTAAAACCCCAAATTATCTAGGTTTCCAAGTAGGAAAAATAAAGATACATATGACTTTTATTATTATTCGATGATAATTAGCTTTATATAATGTGGCATCCTTCATAAAAATTCACTATGTTGTGAGGCAAACAGATTTCTCACTATCATCCAGTGTACCCTGCTCACCTTCTCACTCCTAGCACCGTTCTTCTGGTCTGTGTTGAAAAGGGTATCATTCATGTGGTTTCAGTTTAGAAGAGTCCCTCAGAGCTTTGCCTCAAGCAATTTCAAATTGTAGTGATACCTTAAATCATGTATTCAGGATGCCTTCTTTAGCATTTAGAACCCCAACTAGACTTATACTTTGACTAAAGTCAGAGGCAGACCAATTTAGGGAACAGATTTTGTTCTTTGCTTTTATGATACATTTGTAACTCACAGCTGTTAGCATGACCTCACATCACTGCGTAGGACCCGGAAATCACATCTCCTGGTCAGGTCACGAAAAAGAACACAGGCTTGACTATTGTCCAGAAGTTACTTTCCCCTTGACTAAAGGTTTCCCCTTAGGGTACACATTGCTATTTAACTTTGCCTCCTACCCTTTTTTGTTACCTTCCAAAATCAAGACACTTTTAAGAAACAAAGATAGTTTTCTGAACATTCTGTGTCCTGCCTGTCTCCTGTTGATTCGCAGATGTAATATCGAGTATTCATCAACTGGTCTCAATTTCCTGAACACATTCACTGTATCCCTCATTGTCACCGTTATCCCCCTGCTTCAAAATGTGCCAGTTCCACTTGGTAATAACGTTGGGAAAATGCAGGTTTATGAATGATGTGGACTTTTAGAGGATCAAATCAATAAATTGGATTTTTTATTTTTTGAGGGCAGCTGCCCTCACTGTTTTAAATAAAGAATCTTACATAAGAATGTTGACAACATTCACAGTAAGCCATTGGCAGAAAATTGATCTGCATGTCCTAGACCAATGATTACAAGGTGTCTGTGGTTTAGGGGGCCCAGCCCATCATTCCTTTTCCCCTTGGCACTCATGAGAGAGATGCCAAGTTCAGTGTGGATTTTTCTTGGTGCTCTATGGAGAAATGGAGTCTGTGTGCTTACTGAAGAGTCCCAAAAACCAGAGACCATTTTCATTTACTGCCATCATAAATATTCTCCACCATTCAAGATGCCTGTGTACACGGCTATTTGGGAAACTTAAGTGTTGGAGGAGGCAGGGGCTGAAGGTGTCAAAACCTCCTCAGTAGGATAACCCCTTTCTCCCCTTTGGACCATCTGCCATCTTTCATGAGTGTTTCCCATGGTGTTTTTGCATCCAGAGTTGACAACAACTCAATTTTGCCTTGAATTTACTCAGTCTTATAAATTAAAAATGTGCATTTTATATAAAGATGCATTTTATATAAAAATGCACACCTTTAATCTCTATATGGCAGCatatacatatatatatataAAATGCACACTTTTAATCTCTATATGGCAGCATTTTTGAGGCTTTATATCTGCCCGTGTACCCTCAACTGCCTCCTTTTTGCAGAGAACGATCCCCACAGGAACTGGTCTAAGAACACTGTCTGCACATGATTGATGCTTAAAATCCAATATACCACCACATATCAAAGGTTGGGATTTTCAGAGTCCTTCTTGATTTCTGAGCTGAAACCTTAACAAATAGGGAATTTGGCAGGGAAGACACCTGGGTTTTTAATTCAGAACCCTATTTATATACTGTTAAAATTTGAGGTACTGTAGTTTATATAAAAGTCGGATGTTAAGATATTATATTTCAGTACTAGGAGCTTCTTTGCAGTCATTAACATGACAAATTAAGTAATAAATATAAAAGTGATTGTCCATAAATTATCATTGAATTTTTTGTTTATTTTGTAGTGTTCTGTATTTATCTGCACTTTGTGTATATATACACACATACATATGCCAACATGTAAATAACCTCATGTTTATTCCTAATCTAAATTGCCACAATATTTTTAATGTATGGTTACACTGTGTTTTAAATTACTTTAAAAATAAACTTTGTAAGCAGATTTTAA

>NM_001367945.1 

ACAACGCCGACGACTGTCAAGAGAGTTGGGGAGTGGAACTGCCGGAAGTGTCTGCGCGCCGTGAGAGAAACTTTCCTGCTCCGGCCGCGGCCCGGAGCCTCGCCGCCCCCGCGTTCCGAACGACGATGCGTCCAGATGACAACAACCTGAGGGGACTcgcgcctcggcccgccgcccgcgcctgcgctcgcCTAGCCTCGGGGGAGGAAGACTGAGCCCGGCGCAGGCGGCGCGGCGCTCGGGGCCCGTTTCCTCCGCGCAATCAGTCCCCTCGCGTCCCGGCGCCTTCCCCGCGATCGCGCGACCCCAGCGCCCGCCGCGGCCGCCGGCTGCCCCCGCCCTGACCTCCGGCCCGGACGTGTCCGCGGCCGCCGCTGGCAGCGCCTGTGCCATGGGGCTGCCCACTCTGGAGTTCAGCGATTCCTACTTGGACAGCCCAGATTTCAGGGAGCGCTTGCAGTGTCACGAGATTGAGCTGGAGCGAACCAACAAGTTCATCAAGGAGCTCATTAAGGACGGCTCTCTGCTCATTGGGGCGTTGAGGAATCTGTCTATGGCAGTGCAGAAATTTTCCCAGTCATTGCAAGATTTCCAGTTTGAATGTATTGGTGATGCTGAAACAGATGATGAAATTAGTATTGCTCAGTCACTAAAAGAATTTGCAAGACTACTCATTGCAGTAGAAGAAGAAAGGCGAAGACTGGCAATGTTTTAAGAGGTTTTGCTGCCAGCCCCCAAAAAGCAGGCGATAAAAATGAGAATAGCCTGACATTTCCATGGCAAACTTCTTGGTGTTGTTGTAACTGGAGCTTGGATGAGGATGAGACAAGCCACATTGGAGAATGTGCTTCCCTTTCCAGCTGTCCGGCTGTCTGGGGAGATGTAAGAAAAGGTATCTGACTTAGCCTTGGAGGAAGGCTTACAATCTAGTTAAATAGAAAAGCCTATTATAAACCTGAAGCATTTCAAAAACATGGCCTGGTTGAATTGTGATGAGCTCCCTATCCAAAACGCTAACGATGTATTAATTGCACCACTTGAGAAATTTCGAAAAGAACAGATAGGTGCAGCAAAAGATGGAAAGAAGAAGTTTGACAAAGAGAGTGAAAAATATTACTCTATCCTTGAAAAGCATTTAAATTTGTCCGCAAAGAAAAAGGAGTCTCATTTACAAGAGGCAGATACACAAATTGACCGAGAACATCAGAACTTCTATGAAGCATCATTAGAATATGTCTTTAAAATTCAAGAGGTCCAAGAAAAAAAGAAGTTTGAATTTGTTGAACCGCTTTTGTCATTTCTTCAGGGCTTATTTACTTTTTACCATGAGGGATATGAACTTGCCCAGGAATTTGCACCGTATAAGCAACAGCTGCAGTTCAACTTGCAGAATACAAGGAATAATTTTGAAAGTACTCGACAAGAGGTAGAGCGGTTGATGCAAAGGATGAAATCTGCTAACCAGGACTACAGACCACCCAGCCAGTGGACGATGGAAGGCTATCTGTATGTCCAGGAGAAACGACCGCTTGGTTTTACATGGATTAAACATTATTGTACATATGATAAGGGAAGTAAAACATTTACAATGAGTGTTTCAGAAATGAAATCCAGTGGGAAAATGAATGGCCTTGTTACTAGCTCACCGGAAATGTTTAAATTAAAATCTTGTATCCGACGAAAGACAGATTCAATTGACAAACGATTCTGCTTTGACATAGAAGTAGTTGAAAGGCATGGGATCATCACGTTACAGGCCTTCTCAGAAGCTAATAGGAAACTCTGGCTTGAAGCCATGGATGGGAAGGAACCGATTTATACTCTGCCTGCCATTATAAGCAAGAAAGAAGAAATGTATTTGAATGAAGCAGGGTTCAACTTTGTGAGAAAATGCATTCAAGCTGTGGAAACAAGAGGTATCACCATTTTAGGACTCTACCGAATAGGAGGAGTGAACTCCAAAGTTCAAAAACTCATGAATACCACATTTTCTCCTAAATCCCCTCCTGATATTGATATTGATATTGAACTGTGGGACAATAAGACGATAACAAGTGGGCTGAAAAACTACCTCAGGTGCCTTGCAGAACCACTGATGACTTACAAGTTGCACAAAGATTTTATCATTGCTGTTAAATCTGATGATCAAAACTACAGGGTGGAGGCTGTACATGCATTGGTGCACAAATTGCCGGAGAAAAACAGAGAGATGCTGGACATCTTAATAAAGCATCTGGTCAAAGTATCACTACACAGCCAACAAAATCTCATGACTGTCTCAAATCTTGGTGTCATATTTGGCCCAACTCTAATGAGAGCACAGGAAGAAACTGTGGCTGCTATGATGAATATTAAATTTCAGAATATTGTGGTAGAAATTCTGATAGAGCACTATGAAAAGATTTTTCATACTGCTCCAGACCCAAGCATTCCTCTTCCTCAGCCTCAGTCTCGATCTGGATCCCGAAGGACACGAGCAATCTGCCTCTCTACAGGGTCTAGGAAGCCCAGAGGGAGGTATACTCCATGCCTGGCCGAACCTGATAGTGACTCCTATAGCAGCAGCCCAGACAGCACACCTATGGGGAGCATTGAGTCACTCTCTTCTCATTCCTCTGAACAAAATAGCACTACAAAGTCAGCTTCCTGCCAGCCCAGGGAGAAATCTGGAGGGATTCCTTGGATTGCAACCCCATCATCTTCCAATGGACAGAAAAGCCTTGGTCTGTGGACAACTAGTCCTGAATCAAGTTCCAGAGAAGATGCAACCAAGACAGATGCAGAATCAGACTGCCAGAGTGTTGCTTCAGTCACTAGCCCAGGAGACGTTTCCCCACCCATAGACCTAGTCAAGAAAGAGCCTTATGGGCTTTCAGGACTGAAAAGAGCTTCTGCTTCTTCTCTCAGATCCATCTCTGCAGCTGAAGGAAACAAGAGCTACAGTGGATCTATTCAAAGCTTAACTTCTGTAGGTTCCAAGGAGACACCCAAAGCTTCACCAAACCCAGACCTGCCTCCGAAAATGTGCAGGAGATTAAGACTAGACACTGCCTCAAGCAATGGCTATCAGCGGCCTGGCTCAGTAGTGGCAGCAAAAGCTCAACTGTTTGAAAATGTTGGTTCACCTAAACCAGTTTCTTCTGGGCGCCAAGCCAAAGCCATGTACTCCTGTAAAGCAGAGCACAGTCATGAGCTTTCCTTCCCACAAGGAGCAATATTTTCTAATGTGTACCCATCAGTGGAACCAGGATGGTTAAAGGCAACTTATGAAGGCAAAACAGGACTAGTTCCAGAAAATTATGTTGTCTTCCTCTAATACTATTTAGTGGATGGCAGTATCTTCATGGTATCCATGGTAACGAATAAATGCTATGATTTTATCTGACACAGATACACGGGGATCAGCCCACTAAGTGAAAACAGTCAATTTCTATCAAGTTCTTCACCAGCAGACTATGTAGCTCCTTATTAATGGAAAAAAAGATTTAAATTGTTGGCCATTCTTTTTTGGTTGGTTTCTTATTTTAAAATATCTTACTTGTGAAAAATGTGTTTTTGGATAATATGTAACTCTCCACAATGTCGCTTCCGTAGCAATTGTAGAGTTTCAAATACTGTGTTAAATACTGTATCCCAGAAATTTGGAAACCAGAAATCTGCTATATGGATTTTGAGATCTGTCCTTTACTGCCTGGCATTCTCTGAGGATCTCTGAAATTGTTACTTAAAAATGTAATTTAAATTGTTCATTTATTGTTTTTTTTTTCTTAGAAATATACTGCTTTTATATATGATTGTTTTGCTGGTCCTAAACATTTCAAGGATGTAAGTCTTTGTTTTAATATAACTTTATTTGTTTTCCAAGTAGATGATAATATTCAAAAGCAATAATGTATATGATATCTATAAAGGAAGCAAAATTAAGTCATACACTGATTCCACTGTAAACAATCTGTCCAGAATTCCAGACACCTtcagcaaactttttctgtaaaggcctgatagcaaatattttTGTGGTGGGTTGAATTTGGCTTATGGGTTATAGTTTGCTGACACCTAGTTTAGAGGGTGTGTAAAACTATCTTCATAACTTTGAGATTTTTATAAAATTTTACATGAAAATATACTGATAAATTATATGCACATATTTTCTACCAGTAGCATTATAGTGGCATCATAGAAGAATATTTACCAATGATGGGGAAACTGTAAAACTACAGTATCAAGGCATACAACTTAAATTCCACTTGGAAGATTGTAAAGTGTCAAAGTATTTTAATGATAATTTAATTTGGGCTTTTGAAATGTTCTTCTACAAATGAAAAAGATGTTTAAAAACGTTACAAGGGAAGCTATGCCTTCTGAAGTCTATCCTTAGTTGAAACAGAAAATAAACACAAAGGTACAAGATCCTTAAATTATTTTGAACCACAGAGGTTGAAATTGTTTTGTGATCTTCAGCAGAAATAAAATCTGTACATGATTTTCTTTTATGCCTTTTAGTTTACAGTCTTTATTAGCAATTTCAGTGAATTTGTAGAGCATAGTAATAGGTATTTACTGTCCACTTATATATATCAGCATCTGGTCATGCACGAACCATTAATTCTATATTTCTATTTCAATAATTCTAATATATTATTTCTATAAATGTAATATCTGTATGTGGCAAAGAGCCTTTCTTCTCAAGATCCTGAAAAGCTGGTTACCTGCCCTTTGAGTGCCACAGTCCTGAACTGCTTGTTCTTGACATCTTGCATATTACTTCAGAGTTCCCCACTGTGCAGACTCTCAGGTATTAACTGTAAAAAACTCTTTACATGCCATTATTATCTGTAATCTCTATCTCTTCTACTTTAAATTAATGTTTCTAGAATTAATAGGTTAAATACACATACACACACACAACTATGCCTCAGAAAAGTTAGGCTTTTACAAATAAAAAGAATAAGATTAGAATTAACAAGTAGAGAGAATAACGGTAGGCAGAGTCAGAATCAGGAATAAATATCAGTGAATCAAAAGAATGAAAAATATTATGTAATAAAAATTAGCAATGTAATGTAAACGTTTGATAAAAGAGTATCTTTTTCTTTTATCTCTTACTGTTGACCTCTGTGCACTGTAATAAGGTGTGTTGCTGGATCTTCTTGGTCGAGGTCCTTGGTGACCTTAGTAGTAATAACAGCATTGCTGACACCCTAATTGCCCTCTGCTGGAACAGAAGGTAGTTTTCCAGTGTACCAGTCCCTTAGTCTATACAGCACCCTTGGTTTAAGCACACTTGCCATCATCTGGTATCCTGCTAGACTAGAATCTCTTAAAAGCAAATTGGTTTTCTTTCAAAGACCAACTTGACTCCAAAGAGAGATTCAGAATCCTACTTCTCCTGCTGCTGCATAAAGAATCTCAACCTTCATTTTATTTGAACACGGACCAAAGTGTTCCTGCTTCTGAGTTGTCTGTAAGCTAATTCTGCAGATGTTCCATTCAGATTTAAAGCTTTTTTACTGCATAGGATGTGGATAGGAAGCCTAACTATTGTATCTGATGGCAAGGCATATGTTGCAGCCACAGTACTGGCTATGGTCCCTTTGCTGAAACAAGCTACAGAAGCACTGATTCAAGTTGTGCTTGTGCTTGAACTTTTAATCTTCTAGATTTGTGAGGATGGCTCTTTTTCCTTCATAATGGATTACAATGTAAGCAAGTCATGGCCATATACTGGAGACGGGCTAAAGCTGCTTTTCCCTTAAAGTAAGTTTCCTACAGATAAGGTATTTATGAGCACTGAGAAAGTCAGGACATGTACTCTAAATCACACAGAATGTTAATTCCACAGGAAGGCAATGCCAGACATTGAAAGAGGATCACATTCAACTTTTAATAGTAGTTCAATAACAAAACCTTAGCTTTTCAGGAACAATGTGAAGATACATTAGAATTGCCACATCCATATCTTCAAAACACGCAACCTCTGCACCCTAATAACTGCTTACGGTATAATCAGTATGATGATGAGATTGAGGGGGTCTAAATTTAAGTTCCTTATCTCCTGAGTTATGTGAAAATATCCCTCAGTACAAAACATTTGTGTGTTTCACAGATGACTCTCTTGTTTTGCCGTAATGCTACCAAGTTTATGGAAACTAGTCAACTGAAGGATTTTTCTGTTGTGTTATGTGTAAATGTCTGAACAGTAAAATCATCTGTGTATTCCTGTAACATTCACGAAGTATGAGGAAGTGGGTTTCTCCTTGTTTGATGTGAGTGGTTTTGCTTGTTGCATGGGTTCCCTGTGCTTTGTAACTTGCATGAACACAACCAGGTTTCTCAACAATGATTTGTCTGCTGACTCTTTTCAGAGATAGTGAAGGAAAAAAAATGTATTAAAACCCCAAATTATCTAGGTTTCCAAGTAGGAAAAATAAAGATACATATGACTTTTATTATTATTCGATGATAATTAGCTTTATATAATGTGGCATCCTTCATAAAAATTCACTATGTTGTGAGGCAAACAGATTTCTCACTATCATCCAGTGTACCCTGCTCACCTTCTCACTCCTAGCACCGTTCTTCTGGTCTGTGTTGAAAAGGGTATCATTCATGTGGTTTCAGTTTAGAAGAGTCCCTCAGAGCTTTGCCTCAAGCAATTTCAAATTGTAGTGATACCTTAAATCATGTATTCAGGATGCCTTCTTTAGCATTTAGAACCCCAACTAGACTTATACTTTGACTAAAGTCAGAGGCAGACCAATTTAGGGAACAGATTTTGTTCTTTGCTTTTATGATACATTTGTAACTCACAGCTGTTAGCATGACCTCACATCACTGCGTAGGACCCGGAAATCACATCTCCTGGTCAGGTCACGAAAAAGAACACAGGCTTGACTATTGTCCAGAAGTTACTTTCCCCTTGACTAAAGGTTTCCCCTTAGGGTACACATTGCTATTTAACTTTGCCTCCTACCCTTTTTTGTTACCTTCCAAAATCAAGACACTTTTAAGAAACAAAGATAGTTTTCTGAACATTCTGTGTCCTGCCTGTCTCCTGTTGATTCGCAGATGTAATATCGAGTATTCATCAACTGGTCTCAATTTCCTGAACACATTCACTGTATCCCTCATTGTCACCGTTATCCCCCTGCTTCAAAATGTGCCAGTTCCACTTGGTAATAACGTTGGGAAAATGCAGGTTTATGAATGATGTGGACTTTTAGAGGATCAAATCAATAAATTGGATTTTTTATTTTTTGAGGGCAGCTGCCCTCACTGTTTTAAATAAAGAATCTTACATAAGAATGTTGACAACATTCACAGTAAGCCATTGGCAGAAAATTGATCTGCATGTCCTAGACCAATGATTACAAGGTGTCTGTGGTTTAGGGGGCCCAGCCCATCATTCCTTTTCCCCTTGGCACTCATGAGAGAGATGCCAAGTTCAGTGTGGATTTTTCTTGGTGCTCTATGGAGAAATGGAGTCTGTGTGCTTACTGAAGAGTCCCAAAAACCAGAGACCATTTTCATTTACTGCCATCATAAATATTCTCCACCATTCAAGATGCCTGTGTACACGGCTATTTGGGAAACTTAAGTGTTGGAGGAGGCAGGGGCTGAAGGTGTCAAAACCTCCTCAGTAGGATAACCCCTTTCTCCCCTTTGGACCATCTGCCATCTTTCATGAGTGTTTCCCATGGTGTTTTTGCATCCAGAGTTGACAACAACTCAATTTTGCCTTGAATTTACTCAGTCTTATAAATTAAAAATGTGCATTTTATATAAAGATGCATTTTATATAAAAATGCACACCTTTAATCTCTATATGGCAGCatatacatatatatatataAAATGCACACTTTTAATCTCTATATGGCAGCATTTTTGAGGCTTTATATCTGCCCGTGTACCCTCAACTGCCTCCTTTTTGCAGAGAACGATCCCCACAGGAACTGGTCTAAGAACACTGTCTGCACATGATTGATGCTTAAAATCCAATATACCACCACATATCAAAGGTTGGGATTTTCAGAGTCCTTCTTGATTTCTGAGCTGAAACCTTAACAAATAGGGAATTTGGCAGGGAAGACACCTGGGTTTTTAATTCAGAACCCTATTTATATACTGTTAAAATTTGAGGTACTGTAGTTTATATAAAAGTCGGATGTTAAGATATTATATTTCAGTACTAGGAGCTTCTTTGCAGTCATTAACATGACAAATTAAGTAATAAATATAAAAGTGATTGTCCATAAATTATCATTGAATTTTTTGTTTATTTTGTAGTGTTCTGTATTTATCTGCACTTTGTGTATATATACACACATACATATGCCAACATGTAAATAACCTCATGTTTATTCCTAATCTAAATTGCCACAATATTTTTAATGTATGGTTACACTGTGTTTTAAATTACTTTAAAAATAAACTTTGTAAGCAGATTTTAA

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