Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RANBP20P
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:20720817-20723346  UCSC
Coordinates (T2T) chr14:14917927-14920458  UCSC
Coordinates (hg19) chr14:21188976-21191505  UCSC
Strand -
Parental Sequence XM_011545772.2
Parental seq. overlap 1913 bp
Parental seq. overlap (%) 71.8%
Genomic Region Intragenic (EDDM3A)
Retrocopy Summary RANBP20P, located on chr14:20720817-20723346, is a retrocopy of the parental gene XPO6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name XPO6
Full Name exportin 6
Also known as EXP6|RANBP20
Coordinate chr16:28097976-28212031
Strand -
Gene summary The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla LOC115932641P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RANBP20P
TTGTGCAACATTGAAACTGATGTGCCATCAGTATTGAAACCTGACCTCATTGATGTACGTGCTCAGTCCCTGGCTGTGCTGCAGGCTTACACTCACTGGTTAGTGCAGTATTGCAGTGAAGCTCACCAGCAGAACACACAGCAGTTCGTGACACTCATCCCTATTACCATGAATGCAATCACACCTCTAATCAGCACCAAGTGGTGGGTCTAGATGACTTGTCTCAGGGGCCCCCGATGAGGCGACCCAGGCAGCCCTGCCCTTTTTAGAGGATCCCCTCGGGGCCCGGGGGGGAAGGGGTTATCTTTGCATGGGTAGGGGACTTCCCTAGTCTGCCGGGACCATGACCTGAACTGGGCGAGTAGGATGTGTCCAAAGCCCAAGAACCAGCTCATCTGAGCCGCCCCCTCCCCGGCCAGCATGGCATCTGAAGAAGCCCCTCTCAGAGCATTGGAAAGGCTGATGACAGAACTTTTTCACGATGGTACGACCAATGAAAGAAAACGTGAGATAGAGGAGCTTCTTAATAACATTGCCCAGCAAATAGGAGCCTGGAGATTCTTCCTGTACTTTCTCTCCAGCACTAGGAATGGCTATGTAATGATGTACAGTTTAACAGTTTTTGAGAATCTGATCAATAAAATGTGGCTTGGGGTCCCATCTCAGGATGAGATGGAAATCCACAGCTGACTGCCCAAACTCCTTTTGGCTCACCATAAAACCTTACCTTACTTTATCCAGAGCAAGTTCTGCAAAGTTATTGTTGATATTGGACGTCAGGATCGGCCCATGTTCTACCATGACTTTTTTACTAACATTTTGCAGTTGAACCAATCCCCTGTGACAACCCCCCTTGGGCCGATCATGTTGAAGACAACTTCAGAGGAGCTGGCTTGTCCCCACGAGGACCTCAGTGTGGCTTGGAAGGAGGAGTTGCAGAAGCTGCCACTGGACCAGGTGCAGACAGTGCTTGGGCTGCTGACCGCTATCTTGGGGACTGTCTGGGACAAACACAGTGTTACTGCTGCCACTCCACCACCCTCCCCGACAGGAGAAAGTGGTGACTTACTGAGTAACCTGTGGCAGAGTCCTAGTTCAGCCAAACTGTTGAATCAGCCAATTCCCATCCTTGATGTGGTGAGTGAGTATATCTGTTCCCTTGCCTTGGAGTGCCTAGCCCATCTCTTCAGTTGTATTCCTCTGTCTGCCGGCATCACCCCATCCCTCCTTACCACCACCTTCCACTTTGCGTGATTTGGCTGTGACATCCGTGCCAGAAAGATGGCGTCAGTTAACGGCAGCAGCCAGAACTGTGTCTCGGTTCAGGAGCGGAGCCGGCCGGGGGTCCTGGCCATGCCCTGCATCAGTGAACTCATTTCCAAGAGCTGTGTGCCGATGGAGTTCGAGGAGTATTTACTGCTTATGTTCCAGCAGACTTTCTACCTCCTGCAGAAGATCACCAAGGATAACAATGCCCACACAGTGAAGAGCAGGCTAGAAGAGCTCGATGAGAGCTTTATTGAGAAGTTTACTGACTTTCTTTGGCTCTTTGTGAGTGTTCACCTAAGAAGAATCGAGTCTTACTCCCAGTTCTCTGTGGTGGAGTTTTTGACACTTTTGTTCAAGTACACATTTCATCAGCCTACTCATGAAGGTTAATTCTCTTGTTTGGATACTGGACACTCTTTTTGGACTATCTGACAAATAAAATTAAAAGTCATCTTGAAGACAAGGAAGCAGTTCTCAACAGGTACGAAGATGCCCTGGTGCTCCTCCCCACAGAGGTGTTGAATCAAATCCAGTTCAGATACAACCAGGCCAGCTGGAGGAGTTGGATGACGAGACTCTGGATGACGATCAGCAGATGGAGTGACAGCGGTACTTACGGCAGAGCTTGGAGGTGGCGGTCAAAGTGATGGAGCTCCTGCCCACGCACACGTTGTCCACACTGTTCCCAGTTCTTCAGGGCAATTTAGAAGTTTATTTGGGATTACAGCAAGTTATAGTTACATCAGGGTCAGGACACAGGTTGAACATCATGGCAGAGAACGACTGCTGGTGGCTGCACTGCTCCCTGAGAGACTTGAGCTCCCTGCTGCAGGCCATGGGCCACCTGGCCGGGTACTTTATTGGGGATGTGTTTGCTGCATGGTTCAATGATGCCCTCACAGTTGTGGAGAGTTTGGTCAAAGTCACTCTGTATGGATCTCAGATAAAGTTGTACAACATTGAg
>XM_011545772.2
GGGTGGGTCTGGATGAATTGTCTCGGGGTCCCCCGATGAGGCGACCCGGGCGGCCCTGCCCTTTTTAGAGGGTCCCCTCGGGGCCCGGTGGGGAAGGGGTTGTCTTTGCATGGGTGGGGGACTTCCCGAGTCTGCCGGGACCATGACCTGAACTGTGCGAGCGGGACGTGTCCGAAGCCCAAGAACCAGCTCATCTGAGCCGCCCCCTCCCCGGCCAGCATGGCATCTGAAGAAGCCTCTCTCAGGGCATTGGAAAGTCTGATGACAGAATTTTTTCACGATTGTACAACCAATGAAAGAAAACGTGAGATAGAGGAGCTTCTTAATAACTTTGCCCAGCAAATAGGAGCCTGGAGATTCTGCCTGTACTTTCTCTCCAGCACTAGGAATGACTATGTAATGATGTACAGTTTAACAGTTTTTGAGAATCTGATCAATAAAATGTGGCTTGGGGTCCCATCTCAGGATAAGATGGAAATCCGTAGCTGTCTGCCCAAACTCCTTTTGGCTCACCATAAAACCTTACCTTACTTTATCCGGAACAAGCTCTGCAAAGTTATTGTTGATATTGGACGTCAGGATTGGCCCATGTTCTACCACGACTTTTTTACTAACATTTTACAGTTGATCCAGTCCCCTGTGACAACCCCCCTTGGGCTGATCATGTTGAAGACAACTTCAGAAGAGCTGGCTTGTCCCCGTGAGGACCTCAGTGTGGCTCGGAAGGAGGAGTTGCGGAAGCTGCTACTGGACCAGGTGCAGACAGTGCTTGGGCTACTGACAGGTATCTTGGAGACTGTCTGGGACAAACACAGTGTTACTGCTGCCACTCCACCACCATCCCCGACCTCAGGAGAAAGTGGTGACTTACTGAGTAACCTGTTGCAGAGTCCCAGTTCAGCCAAACTGTTGAATCAGCCAATTCCCATCCTTGATGTGGAGAGTGAGTATATCTGTTCCCTGGCTTTGGAGTGCCTGGCCCATCTCTTCAGTTGGATTCCTCTGTCTGCCAGCATCACCCCATCCCTCCTTACCACCATCTTCCACTTTGCACGATTTGGCTGTGACATCCGGGCCAGAAAGATGGCGTCAGTTAACGGCAGCAGCCAGAACTGTGTCTCGGGTCAGGAGCGCGGCCGGCTGGGGGTCCTGGCCATGTCCTGCATCAATGAACTCATGTCCAAGAACTGTGTGCCTATGGAATTTGAGGAGTATTTACTGCGTATGTTCCAGCAGACTTTCTACCTCCTGCAGAAAATCACCAAGGATAACAATGCCCACACAGTGAAGAGCAGGCTAGAAGAGCTCGATGAGAGCTATATCGAGAAGTTTACTGACTTTCTTCGGCTCTTTGTGAGTGTTCACCTAAGAAGAATCGAGTCTTACTCCCAGTTCCCTGTGGTGGAGTTTTTGACACTTTTGTTCAAGTACACATTTCATCAGCCTACTCATGAAGGTTACTTCTCTTGTTTGGATATCTGGACGCTGTTTTTGGACTATCTGACAAGTAAAATTAAAAGTCGTCTTGGAGACAAGGAAGCAGTTCTCAACAGGTACGAAGATGCCCTGGTGCTCCTGCTCACAGAGGTGTTGAATCGAATCCAGTTCAGATACAACCAAGCCCAGCTGGAGGAGTTGGATGATGAGACTCTGGATGACGATCAGCAGACGGAGTGGCAGCGGTACTTACGGCAGAGCTTGGAGGTGGTGGCCAAAGTGATGGAGCTCCTGCCCACGCACGCCTTCTCCACACTGTTCCCTGTTCTTCAGGACAATTTAGAAGTTTATTTGGGATTACAACAGTTTATAGTCACTTCAGGGTCAGGACACAGGTTGAACATCACGGCGGAGAACGACTGCCGGCGGCTGCACTGCTCCCTGAGAGACTTGAGCTCCCTGCTGCAGGCCGTGGGCCGCCTGGCCGAGTACTTTATCGGGGATGTGTTTGCTGCACGGTTCAATGATGCCCTCACAGTCGTGGAAAGGTTGGTCAAAGTCACTCTGTACGGATCTCAGATAAAATTGTACAACATTGAAACTGCTGTGCCATCAGTATTGAAACCTGACCTCATTGATGTGCATGCTCAGTCCCTGGCTGCGCTGCAGGCTTACTCTCACTGGTTAGCACAGTATTGCAGTGAAGTTCACCGGCAGAACACGCAGCAGTTCGTGACACTCATCTCTACTACCATGGATGCAATCACACCTCTAATCAGCACCAAGGTCCAAGACAAGCTGCTGCTATCTGCGTGCCACTTACTGGTCTCACTGGCCACCACCGTGCGGCCCGTCTTTCTGATCAGCATCCCTGCAGTGCAGAAAGTATTCAACAGAATCACTGATGCCTCTGCCCTGCGACTTGTCGATAAGCCAAACTGATTATCCACCAGACACTCAGCGTCTTAGAAGATATTGTGGAGAATATCTCGGGGGAGTCCACCAAGTCTCGACAGATTTGCTACC

Publications

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