Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name ARL6IP1P1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:21649603-21650338  UCSC
Coordinates (T2T) chr14:15847261-15847996  UCSC
Coordinates (hg19) chr14:22117819-22118554  UCSC
Strand -
Parental Sequence NM_015161.3
Parental seq. overlap 633 bp
Parental seq. overlap (%) 27.8%
Genomic Region Intergenic
Retrocopy Summary ARL6IP1P1, located on chr14:21649603-21650338, is a retrocopy of the parental gene ARL6IP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ARL6IP1
Full Name ADP ribosylation factor like GTPase 6 interacting protein 1
Also known as AIP1|ARL6IP|ARMER|SPG61
Coordinate chr16:18791667-18801549
Strand -
Gene summary This gene belongs to the ARL6ip family and encodes a transmembrane protein that is predominantly localized to intracytoplasmic membranes. It is highly expressed in early myeloid progenitor cells and thought to be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Mutations in this gene are associated with spastic paraplegia 61 (SPG61). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ARL6IP1P3
Bonobo Pan paniscus ARL6IP1P2
Gorilla Gorilla gorilla ARL6IP1P3
Orangutan Pongo abelii ARL6IP1P3
Gibbon Nomascus leucogenys ARL6IP1P2
Crab-eating macaque Macaca fascicularis ARL6IP1P1
Rhesus Macaca mulatta ARL6IP1P1
Baboon Papio anubis ARL6IP1P1
Golden snub-nosed monkey Rhinopithecus roxellana ARL6IP1P1
Marmoset Callithrix jacchus ARL6IP1P2
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ARL6IP1P1
GATGGCAGAGGGAGGTAACCACGGCACCAATTTGCTGGCTGCAGAGACTGCAAGTTTAGAACAATAGCTGCAAGAATGGGGAAAAGTGATGTTGATGGTGGATAAAGTCTTATTATGGGAAAGAGCTTGGTTTTCACCTGCCATCATGGACTTGGTTTCTTTGGTGCTTCAATTATCTACTATCTAGATCCATCTGTTCTGTCTGCTGTTTCCTCTTTTGTTGTGTTTTGGTGCTTGGCTGACTACCTTGTTCCCATTCTAGCACCTAACATTTTTGGCTCCAATAAATGCACCAGCAATCAACAGCAAAAATTCCATGAAATTTGCAGCAATCTACTAAAAACTCAATGCAGAGCTATGGACTGGTGGAAACAAATCTTCGCACTGAAGGAAGAAAAGCCTGAAATGTGTTTCATGGCCATGATCATTTATCTCGCTGCAGTTGTTTGGATGGGACAGCAAGTCCACAACCTGCTTCTCAGCTACCTGACAGTGACTTTCTTACTGTTGCTTCCTCAACTAAACCAACACGGAATCATTTCAAACCACACTGGAAAGGCCAAAGGGAGATAAACAAGCTTCTCGAACAAAAAGAAAAGAAAAATGAATAATTCATCCACTTTATTCAATGTGATTAATGGCATATACATTGTCCCTAGGAACAGTTTCTGCTATACTATCCAGATACTAAAATGTTAAAGAAGTAGCTCTTTGTTCTCCCTCACTCTACCCTTAA
>NM_015161.3
GGGTTGTGGTTGGTGTGCGGGTTTCGGTTGGAGGACTCGTTGGGGAGGTGGCCTGCGCTTGTAGAGACTGCATCCCCGAGACGATGGCGGAGGGAGATAATCGCAGCACCAACCTGCTGGCTGCAGAGACTGCAAGTCTGGAAGAACAGCTGCAAGGATGGGGAGAAGTGATGCTGATGGCTGATAAAGTCCTCCGATGGGAAAGAGCCTGGTTTCCACCTGCCATCATGGGTGTGGTTTCTTTGGTGTTTCTGATTATCTACTATCTAGATCCATCTGTTCTGTCCGGCGTTTCCTGTTTTGTTATGTTTTTGTGCTTGGCTGACTACCTTGTTCCCATTCTAGCGCCTAGAATTTTTGGCTCCAATAAATGGACCACTGAACAACAGCAAAGATTCCATGAAATTTGCAGCAATCTAGTAAAAACTCGACGCAGAGCTGTGGGTTGGTGGAAACGCCTCTTCACACTAAAGGAAGAAAAACCTAAGATGTACTTCATGACCATGATCGTTTCCCTTGCTGCGGTTGCTTGGGTGGGACAACAAGTCCACAACCTGCTTCTCACCTACCTGATAGTGACTTCCTTACTATTGCTTCCTGGACTAAACCAACATGGAATCATTTTGAAGTACATTGGAATGGCCAAGAGGGAGATAAACAAACTTCTCAAACAAAAAGAAAAGAAAAACGAATGATTCATCTGCTTTAATCAGTGTGATTAATGCAGCACCCATTGCCCCGGGAACCGTTTCTGCTGTACTATCTGGATACTAAAATGTTACGGAAGTAGCTCTTTGTTCTCCCTCACTCTGCCCTTAGTTAATAGAAATTCAGACTCGCCAAGTAAGGCTTCGTGCATAGTGTCTTCATGTCGCGTATAGTTGAGCGCGTTCTTAGCAGTTGGCTTCATGGACAACTCATTAGTGTTTTGACTTTTCTTACCCAGCGTTAATTGAATTCTTGCTTTTAGACAACTTCCTTTTTGTAGTGGTGAACCTTGCCCTTTAGTACAGTTCAAGTGAATCTGGATAATTGTTCATCTTTGCTTTAGCTTAGATACCATGTAGTGGTCTGTGGCTACAGGAAGCTGGTTCTGTCTGCTTCCACAGTCTGCTTAAAAAACTGTCTGACTTCGTGAATATAGAGACCAAGTTTACCACTTCTGATGAAGAGACCAATTAAGATTCATTCCTCATTCTGTTTCTTTCCAGTGGGAGAAGAGTCCCCATGAAATAAGATGAAACTGATTCCATGCACTAGTACATGTAGGCTTCTCCCTTGTGCAAAGCTTAGCAATTTGTAGGAAACTTTGATCTTTTTGTCCAAGAAAAGGAATGTCTGACAGGCTTAAGCTTTCGTCCCCTTGCACTTAGACTCGAAGTTAGTAAATCCTTAAAGGCTTTTTAATAGCAGACTTCCAAAAGATTGCATTTAGGATTTCTAGCATGCTTTTAATTTCAGATTTTCAGCTGACATTAGCTATAGTATACAGTAGGTTAAGACTCATGTCTATGACTTTCACTCTAAGACTGGCAAAAGGACAGCAGTCTTCTATGTTTAGTCAATATTCATTTCAGTAGAAGATAATCTTATCTAATTTTTGAGACCAGAATAAGCCTTTTAAGGTAAACCTCAAAATTATCATTTTATGGTAATACTGACCATTTTAGTCCCCTAGGTTTGACATGGGAGATAGTGACTACACTGGTGTCTGACTTTTTTCCTAGAGATTTCTCCCTGAAAAATACAAGGGCTGTTGGTGAGAGCAGACTTGAGGTGATGATAGTTGGCCTCTGGTCTACAAAGATTTCATAACTCCTTGGAAAGCTTCTTATAATCATTCTTAACTTCTTGGTAGCTAGAAATTTAGAGTAGTTGAAATCTTTAGGAATGAACTTCTGAGGGCCAAAAAATGTGACTGACGGGAACAATTCTTAAACTGATTAACTAGCTGTAATATAGTTTTGTGAATTTATTGCACTGATGTTGTACCTTGTGGTATATCTGTCCCTATTAAATAAGTGTTGTTTTCTCCTCTTTAATATTGCTGTGAACAGTGGTGCCCATTGTAGCATATGTTTGATTTTTTTTTATTATTTCATAAGAAAACTACGTTAATTTTACCTTACTTTCATTGTAAATAAGCCTGTCTTCCTATCTGGATTTTTTGTGTGCATACATATTCTACTGATTAACTACTTTTGCAGTTTTAATCCTGTATTATTTCTTCTACTTTGTTTTGTGTAAAAGGGGAAAAAATAAAAAAAGCTGGAATCTT

Publications

PMID - Link Title