Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NARS1P3
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:31286124-31288364  UCSC
Coordinates (T2T) chr14:25484008-25486248  UCSC
Coordinates (hg19) chr14:31755330-31757570  UCSC
Strand +
Parental Sequence NM_004539.4
Parental seq. overlap 726 bp
Parental seq. overlap (%) 26.2%
Genomic Region Intergenic
Retrocopy Summary NARS1P3, located on chr14:31286124-31288364, is a retrocopy of the parental gene NARS1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NARS1
Full Name asparaginyl-tRNA synthetase 1
Also known as ASNRS|NARS|NEDMILEG|NEDMILG
Coordinate chr18:57600656-57621836
Strand -
Gene summary Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla NARS1P2
Orangutan Pongo abelii NARSP2
Gibbon Nomascus leucogenys NARS1P1
Green monkey Chlorocebus sabaeus NARSP2
Crab-eating macaque Macaca fascicularis NARSP1
Rhesus Macaca mulatta NARSP1
Baboon Papio anubis NARS1P1
Golden snub-nosed monkey Rhinopithecus roxellana NARS1P1
Marmoset Callithrix jacchus DYNLL1P11
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NARS1P3
TCAACAGACACATGATGATCTTCGGAGAAAACATGTTCAAACTCTGAAAAGCACGATCCATGGCCACCAGGTGCTTTAGAGATCACTTCTTTGATGGGGGTACTGTGACGTTACTCCTCCAAAAATAGTGCAAATACCAGCAGAAGGTGGTGCTACACCAAACGACTATTTGGGGGAAGAGGCcCATGAAGAGACATTTTTGACTTAGTTCTCTTAGTTGTACCAGGAGACATGCATTCCAGCCCTAGATGTTTTTTTGTATTGCACAGTCATACAGGGCAGAGCATCCAGAATTTGAAGGCACTTGGCTGAATACACTCATGTGGAAGCTGGGTGCCCTTTTCTGACCTTTGAGGGCCTCCTGAACTGATTGGAGGGCTTGGTTTGTGATGTGGTAGTCTTTAAGTCACTGGCAATGAATATATAACCTGAACCCTTACTTTAAGCCCACCAAACGGCCTTTTAAACAGATGCTATGGTGTGGCTAAAACACAATATAAAGAAAAGATATGGAACTTCCTGGGAATTTGGAGAAAAAGTCCCAAAAGCTCCTGAGACTGATGACAACACCATTAATGAACCAATCTTGCTGTGTTGATTTCCTGTGATCAAGTCCTTCTATATGCACTGACATCCTGAGCATTCCTGTCTTACTGAATCTGTCAGTGTGTTGATGCTGAATGTTGGTGAGACTGTGGGAGGATCAATGCATATCTGGGATAATGAAGAAATGCCTGCAGGTTTATAAAAAGGAAGGGATTGACCCTACTCCCTATTACTGGAATACAGATCAGAGAAAATATGGTATATGTCATCATGGAGGATATGACTTGGGCCTAGAATGATTCTT
>NM_004539.4
AGATCTACGCTCTCTGATGCAACGCCGGAATCGCGGAAACCGCCGGTGCACGTTGGAGTCATAAGACGGCGTCGGTGTTGCAGTCTGTGTCCTTGGAGGTGACCAGGGCCACTGCAGGCATGGTGCTAGCAGAGCTGTACGTCTCTGACCGAGAGGGAAGCGATGCCACGGGAGATGGAACCAAGGAGAAACCATTTAAAACAGGTCTAAAGGCTTTGATGACAGTAGGGAAAGAACCATTTCCTACCATTTACGTAGATTCACAAAAAGAAAATGAGAGGTGGAATGTTATTTCTAAATCACAGTTGAAGAACATTAAAAAGATGTGGCATAGGGAACAAATGAAGAGTGAATCCCGGGAAAAGAAAGAGGCAGAAGATAGTTTACGAAGAGAAAAGAACCTGGAAGAAGCAAAGAAGATTACCATTAAAAATGATCCAAGTCTCCCAGAGCCAAAATGTGTGAAGATTGGTGCGTTAGAAGGATATAGAGGCCAAAGAGTAAAGGTGTTTGGCTGGGTCCACAGGCTGCGCAGGCAAGGAAAGAATTTAATGTTTCTGGTGTTGCGAGATGGTACAGGTTATCTTCAGTGTGTCTTGGCGGATGAGTTGTGTCAGTGCTACAATGGAGTTCTCTTGTCCACGGAGAGCAGTGTTGCAGTGTATGGAATGCTAAATCTTACCCCAAAGGGCAAGCAGGCTCCAGGTGGCCATGAGCTGAGTTGTGACTTCTGGGAACTAATTGGGTTGGCCCCTGCTGGAGGAGCTGACAACCTGATCAATGAGGAGTCTGACGTTGATGTCCAGCTCAACAACAGACACATGATGATCCGAGGAGAAAACATGTCCAAAATCCTAAAAGCACGATCCATGGTCACCAGGTGCTTTAGAGATCACTTCTTTGATAGGGGGTACTATGAAGTTACTCCTCCAACATTAGTGCAAACACAAGTAGAAGGTGGTGCCACACTCTTCAAGCTTGACTATTTTGGGGAAGAGGCATTTTTGACTCAATCCTCTCAGTTGTACTTGGAGACCTGCCTCCCAGCCCTGGGAGATGTTTTTTGTATTGCTCAGTCATACCGGGCAGAGCAGTCCAGAACACGAAGGCACCTGGCTGAGTACACTCACGTGGAAGCTGAGTGTCCTTTCCTGACTTTTGACGACCTCCTGAACCGGTTGGAGGACTTGGTTTGTGATGTGGTAGATCGAATATTGAAGTCACCTGCAGGGAGCATAGTGCATGAGCTCAACCCGAACTTTCAGCCCCCCAAACGGCCTTTCAAACGGATGAACTATTCAGATGCTATCGTTTGGCTAAAAGAACATGATGTAAAGAAAGAAGATGGAACTTTCTATGAATTTGGAGAAGATATCCCAGAAGCTCCTGAGAGACTGATGACAGACACCATTAATGAACCAATCTTGCTGTGTCGATTTCCTGTGGAGATCAAGTCCTTCTACATGCAGCGATGTCCTGAGGATTCCCGTCTTACTGAATCTGTCGACGTGTTGATGCCCAATGTTGGTGAGATTGTGGGAGGCTCAATGCGTATCTTTGATAGTGAAGAAATACTGGCAGGTTATAAAAGGGAAGGGATTGACCCCACTCCCTATTACTGGTATACGGATCAGAGAAAATACGGTACATGTCCCCATGGAGGATATGGCTTGGGCTTGGAACGATTCTTAACGTGGATTCTGAATAGGTATCACATCCGAGACGTGTGCTTATACCCTCGATTTGTCCAGCGTTGCACGCCATAACCATTTTCTCCAGAAGCGTGGAGGAAAGATTATGAAAGGAACAGGCTCTTTAAAAAAGAAAACAAAAAGCCAGAATCTTCCTTTTTTTGTTTCATTGGGGTTTCTCTTTCTGTTTTTCTTTCTACTACCATAAAAACTATCTCAAATCACCTGAACATCAAGTGATATTAAGGTTGTCATCTTAAGAAAAAATATCCATTTTTTTCTTAAGTTCGGGAAACAAAGTTCGGGGAAAATACCTGGCATGAAACTGTAGTTAGGGATACATTTCAGCATTTTACTCACTTTATCCAAGTTATTCATTTTATTCAAGTTATATGTATGTATAATTCAACAATTTTAGATTATGGTGTAAGATACTCCAGTAACTTATCTTTCTGTCCTTTTAAGTGTACCTTGAATTCTTTGATTTATTTTATTGCATCAATGAATTAAAACAAAAATCTTGGGGGAAGAAATTGGCAATATCGTATAAAAATCTGCTCATATTAGAACACAGTATAATTCAGCAGTAAACACTAGAATCAAATGAATAGCCTTTTGTATCAGTTATTAATCTTTTCTAACTCTGCTTAGCTGCTAATAATCCTGAGGCATAGAAATTGAAGAATTTGTAAAAATAGAATTGCCTTAAAGGATTTGAAGTAAGAACATAATTTTGGGGAGAGTTTTTTAGTGATTCACAGTATCCCTCTTAGCATTAATTTAAGGTAAAGAGGCAGATTGATTTTCCCTCTTTCCTGGTAATTCCTAAGTAATTAAGAATAAATAAGTTCCAAAAGAAATTGTAGCTGGAATCTTAATAACAATTGTGAGTGGCTGTTTGAGTTGCCCCCACCATGTCCTTAGATCTAATCTGTGCTACCTTATTAACTCACAGCAGGCTTACTGAATGGCTTCATTTCAGATTTAGTTGATTTCTCCACCAAATGCATGTCATGTATTCTCAATAGGCTGTATTCCCAGCAGTCAATAAATGAACACCCGTAAAAACTC

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