Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name QRSL1P3
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:35765836-35767112  UCSC
Coordinates (T2T) chr14:29953576-29954852  UCSC
Coordinates (hg19) chr14:36235042-36236318  UCSC
Strand +
Parental Sequence NM_018292.5
Parental seq. overlap 1167 bp
Parental seq. overlap (%) 28.4%
Genomic Region Intragenic (RALGAPA1)
Retrocopy Summary QRSL1P3, located on chr14:35765836-35767112, is a retrocopy of the parental gene QRSL1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name QRSL1
Full Name glutaminyl-tRNA amidotransferase subunit QRSL1
Also known as COXPD40|GatA
Coordinate chr6:106629578-106668417
Strand +
Gene summary Enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA(Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 40. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes QRSL1P3
Bonobo Pan paniscus QRSL1P3
Gorilla Gorilla gorilla QRSL1P3
Orangutan Pongo abelii QRSL1P3
Gibbon Nomascus leucogenys QRSL1P1
Green monkey Chlorocebus sabaeus QRSL1P1
Crab-eating macaque Macaca fascicularis QRSL1P3
Rhesus Macaca mulatta QRSL1P3
Baboon Papio anubis QRSL1P3
Marmoset Callithrix jacchus QRSL1P1
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>QRSL1P3
GTAATGCTATAGTAGTTCCGAAATTGTTGGATTAGGGAGCTCTACTAATGGAAAAACAAATTTAGATGAGTTTGCTATGAGATCTGGAAATGCAGAAGGCGTATTTGGACCAGTTAAAAACCCCTGGAGTTATTCAAAACAATATAGAGAAAAGAGGAAGCAGAATCTCCACTTTGAGAATGAAGATTCAGACTGGCTGATAACTGGAGGAAGCTCAGGTGGGAGTGCAGTTGCCATATCGGCATTCACATGCTATGCGGCTTTAGGATCAGATACTGGAGGGCTGACCAGAAATCCTGCTGCCTACTGTGGGCTTGTTGGTTTCAAACCAAACTATGGCTTAGTTTCCCATCATGGTCTCATTTCCCTGGAGGATTTGATGGAAGTGCAAGGAATCTTAACCAGATGTGTGGATGATGCAGCAATTGTCTTGGGTGTACTGGCTGAACATGACCCTACGGATTCTACCACAGCACAGGATCCTGTTAAACCATTCATGATTCCCAGTTTGACAAATGTGAGCAAACTATGTATAGGTATTCCAGAGGAATATCTTGTACTGGAATTATCAAGTGAAGTACAGTCTCTTTGGTCCAAAGCTGCTGACCTCTTTGAGTCTGAGGGGGCCAAAGCAATTGAAGTATCCTTTTCTCACATTACTTATTCAATTGTCTGCTACCATCTATTGTGCACATCAGAAGCAGCATCGAGTATAGCAAGATCTGATGGGCTACAATATGGTCACAGATGTGACACTGATGTATCTACTGAAGCCATGTATGCTGCAACCAGACGAGAAGGGTTCAATGATTTTGTAAGAGGAAGAATTCTCTCAGGAAATGTTTTCTTGTTAAAATAAAAATATGAAAATTATTTCATCAAAGCACAGAAAGTGAGATGCCTCATTGCTAATGATTTTGTGAATGCTTTTAACTCTGGAGTATGCTAACTCCCACCACCTTGAGTAAGGCAGTACCATACCTGGAATTCATCAAAGAAGACCACAGAACAGGAAGTGCCCAGGATGATATTTTTACACAGGCTGTAAACATGGCAGGACTGTCAGCAGTGAGTAACCCTGTTGCACTCTCAAACCAAGCGTTGCCCACAGGGCTGCCGTTTACTGGACATGCATTTTGTGACTAGCAGCTTCTTACAGTAGCCAGATGGCTTGAAAAACAAGTAAAGTTTCCTGTTATTCAACTTCAAGAACTTATGGATGATTGTTCATCAATCCTTGAAAATGAAAAGTTAGTCTCTGTCTCTCTAACACAGTA
>NM_018292.5
AGTGACAATTAAAGATGGCTGCGCCCATGTAACATCACTAGCGACCGGTGACCTCTTTTTCCCCCTTGCCTGGCTCCTGTGGTGGCAGGCTGGGCACGAGGACCATGCTGGGCCGGAGCCTCCGAGAAGTTTCTGCGGCACTGAAACAAGGCCAAATTACACCAACAGAGCTCTGTCAAAAATGTCTCTCTCTTATCAAGAAGACCAAGTTTCTAAATGCCTACATTACTGTGTCAGAAGAGGTGGCCTTAAAACAAGCTGAAGAATCAGAAAAGAGATATAAGAATGGACAGTCACTTGGGGATTTAGATGGAATTCCTATTGCAGTAAAAGACAATTTCAGCACTTCTGGCATTGAGACAACATGTGCATCAAATATGCTGAAAGGTTATATACCACCTTATAATGCTACAGTAGTTCAGAAGTTGTTGGATCAGGGAGCTCTACTAATGGGAAAAACAAATTTAGATGAGTTTGCTATGGGATCTGGGAGCACAGATGGTGTATTTGGACCAGTTAAAAACCCCTGGAGTTATTCAAAACAATATAGAGAAAAGAGGAAGCAGAATCCCCACAGCGAGAATGAAGATTCAGACTGGCTGATAACTGGAGGAAGCTCAGGTGGGAGTGCAGCTGCTGTATCGGCGTTCACATGCTACGCGGCTTTAGGATCAGATACAGGAGGATCGACCAGAAATCCTGCTGCCCACTGTGGGCTTGTTGGTTTCAAACCAAGCTATGGCTTAGTTTCCCGTCATGGTCTCATTCCCCTGGTGAATTCGATGGATGTGCCAGGAATCTTAACCAGATGTGTGGATGATGCAGCAATTGTGTTGGGTGCACTGGCCGGACCTGACCCCAGGGACTCTACCACAGTACATGAACCTATTAATAAACCATTCATGCTTCCCAGTTTGGCAGATGTGAGCAAACTATGTATAGGAATTCCAAAGGAATATCTTGTACCGGAATTATCAAGTGAAGTACAGTCTCTTTGGTCCAAAGCTGCTGACCTCTTTGAGTCTGAGGGGGCCAAAGTAATTGAAGTATCCCTTCCTCACACCAGTTATTCAATTGTCTGCTACCATGTATTGTGCACATCAGAAGTGGCATCGAATATGGCAAGATTTGATGGGCTACAATATGGTCACAGATGTGACATTGATGTGTCCACTGAAGCCATGTATGCTGCAACCAGACGAGAAGGGTTTAATGATGTGGTGAGAGGAAGAATTCTCTCAGGAAACTTTTTCTTATTAAAAGAAAACTATGAAAATTATTTTGTCAAAGCACAGAAAGTGAGACGCCTCATTGCTAATGACTTTGTAAATGCTTTTAACTCTGGAGTAGATGTCTTGCTAACTCCCACCACCTTGAGTGAGGCAGTACCATACTTGGAGTTCATCAAAGAGGACAACAGAACCCGAAGTGCCCAGGATGATATTTTTACACAAGCTGTAAATATGGCAGGATTGCCAGCAGTGAGTATCCCTGTTGCACTCTCAAACCAAGGGTTGCCAATAGGACTGCAGTTTATTGGACGTGCGTTTTGTGACCAGCAGCTTCTTACAGTAGCCAAATGGTTTGAAAAACAAGTACAGTTTCCTGTTATTCAACTTCAAGAACTCATGGATGATTGTTCAGCAGTCCTTGAAAATGAAAAGTTAGCCTCTGTCTCTCTAAAACAGTAAACATATCTTACAAATTAAAATGACTTTTAggctgggtgcagtggctcacacctgtaatcccagcactttgggaggccaaggcgagcggatcatgaggtcagaagatctagaacagcctggtcaacatggtgaaaccccgtctctactaaaaatacaaaaattagccaggcttagtggcgggcatctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaaccctggaggtggaggttgcagtgagccgagatcatgccactgcactgcactccagcctgggtgacaaagcaagactgtgtctcaaaataaataaataaaataaaataaaaTGACGTACAGAGATTCTATATTCTAGAGAGTCAAATGGTCTTGCTCAATTCTTGTAATTAGGTTCTTGTTAATACAGTCATTCCATGGAATTACTTTTTAAAATTCCTGTGACAATTAATAATAAATAACGTGTCAGCATTTAGTAAGCATCCACTAAGTGTACAATACttctacaataacacaagatacctgttcctcaaagacaatgcattctgccataatgttcattaaagagtttacagtaaaaataagattagggataaacttctcaaaaattgtacatctgtgtaactaaagcactaacaaaaacatgaatagtcctTCTAGAGGTAACTTGGATAGCCTAGGCAGGCAACTTATCATGTGGTGAAGGCCGCCTCAGGGGTTGTTAAAAATGCACAGAAACAATTGAGTGCGATTATTGGCTTCTGAGCGCTGAGCAGAGCAGGTGGAAGAGGAACTTTGAGCACAGGAGGAAATGCAACCAGTCAGGGCCCAGAATCATGCAAATCTCAGGGGTATGCCTCTCTGGGGAGGAGCTCCACTTGCAGGGACTCCTTTTATTTCCCTAAGAAAGAGCTGAAATGACTGAGAACTTTCCTTTCCTCCTTAGAGTTACAATTTTACTTCTGCTATTCCGGAGCCCATgcctagaagccagaacaactccatgttacactgagttcatgctcctatttactgatcacaaatgagctcattaatgtcatcgaaacatttattgtaacctaacagacCATCACAGATTGGAAACTTGGTAGATAGCAGAGCATGGTATTAGTGAAAAAGGTTCAAAATACACAAGTAACATACACTCTGAAAAACATGCAGATAATTTGCTGATGAAGCAGAAGAGGGGATGCGCATGGCAAGAACTTGCCTTACCCCAGATTCTCTATATCTCATGGTTTCCTTTTCCTCTTGACTGTCTTTACGAGTGTTTTTTATTTGggaccctcgagcccagagatattaatggatatctgtattcaatatttgacaaaatctaatggaaaccatccatttactcatgataaggcttcaTCACTGGATTTCTGTGTCTTCACTAGaacaccattgtcatctcatattgatcaggtattttaatctagcacttacatattgttgataaatgaaagctgaattgttacttaataaattcactttgtttagtaaaaaaaaattgttttctaaatatgacgttcatgaagagaaaataatgaGTCAGAATCATCTGCAGAACCACTGGAATGTTTCATCGTCACCTGTTAGTTTTCATAAACAGTTTTCTGTCCTCTCTGAGATCCTCCCGCTCCCAAATACTCAACCTGATTAACTTCACATAAAAGTCTTATGTGCCAGGCTTAGTAATATTCCTATAGATTTTGACTCTGAATCCCTGAAAGAGGAAGAAATCCATGAGAGAAAATTGCATTACTTTATAGCAAGAGGAAACCGTTTTAAGTTTTTTAATTGCTCAGACACCACAACATCCTAGATGGAGGAAACCATTTTAGTTGAAGGAGCAAATATGATGTCAAAAGCAAGTAAATAAACAAACCGTTGCCCCAATCTGTTTTTATGTAATGAATTTAAAAAAAAAGAGAGAGAGAGagagatgggctctccctgtgttgcccaggctagtctcaaactcctgggctcaagtgatctgcctccctcagcctcccaaagtgctgagattaaagacgtgagccaccacacctggccGaaataataatattcaatattatatattcaatgatattattcagtattcaatattatttcaaataatattaaatCTCTTGTTCCTGTATCTCTACATGAGCTGCACTAATAATTTGAATCTGGAAATTAAAAAGTGAAACATTTACCGTTCTCATATACTGATACCCAACTACCATGAAATGATACCTAATTTGTTTTTCTTTTCTCTTCATTTTTACTCTTAATCTAGTAGGTCTCATTTTGCCAAGTCACTGTCTGGGAATTTAAGTGGCAAATACTTTCTTTGTCTCAGCTAATTAAACTCTAAAATTATTAGCAACAGAA

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