Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HNRNPUP1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:43300267-43300909  UCSC
Coordinates (T2T) chr14:37491190-37491832  UCSC
Coordinates (hg19) chr14:43769470-43770112  UCSC
Strand +
Parental Sequence NM_004501.3
Parental seq. overlap 621 bp
Parental seq. overlap (%) 9.1%
Genomic Region Intergenic
Retrocopy Summary HNRNPUP1, located on chr14:43300267-43300909, is a retrocopy of the parental gene HNRNPU. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HNRNPU
Full Name heterogeneous nuclear ribonucleoprotein U
Also known as DEE54|EIEE54|GRIP120|HNRNPU-AS1|HNRPU|SAF-A|SAFA|U21.1|hnRNP U|pp120
Coordinate chr1:244850297-244864543
Strand -
Gene summary This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HNRNPUP1
Bonobo Pan paniscus HNRNPUP1
Gorilla Gorilla gorilla HNRNPUP1
Orangutan Pongo abelii HNRNPUP1
Gibbon Nomascus leucogenys HNRNPUP1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HNRNPUP1
ATGGTGGAAATTTCAGAGGAGCCCCTGGGAACCGTGGCGGATATAATAGGAGGGACAACATGCCACAGAGAGGTGGTGGTGGCGGCGGAAGTGGTGGAATCGGCTATCCATACCCTCGTGCCCCTGTTTTTCCTGGCTGTGGTAGTTATTCAAACAGAGGGAACTACAACAGAGGTGGAATGCCCAACAGAGGGAACTACAGCCAGAACTTCAGAGGACGAGGAAACAATCGTGGCTACAAAAATCAATCTCAGGGCTACAACCAGTGGCAGCAGGGTCAATTCTGGGGTCGGAAGCCATGGAGTCAGCATTATCCCCAAGGATATTATTGAATACCCAAATAAAACGAATTGATACATATTACTCCAAAACCTTCACAAGAAGTCGACTGTTTTCTTTAGTAAGCTAACTTTTTAAACATTCCTCAAGAGGAATTGCCTGCGGGTTCCTTTTTTAGAAGCTTTGTGGGTTGATTTTTTTTTCTTTTCTTTTTTGTACATTTTTAATTGCAGTTTAAAAGTGAATCGTAAGAGAACCTCAGCATTGTGCACAATAAGAGAATGTGTCAGTATTTCAGGGTTCTACATTTTATCTGTAAAATTTGACTTTTTTTTTTAAATCAGAAATAAAATGTTGCTTTGTA
>NM_004501.3
CTCGCGCCAGGCGAGTCTCCGCGTCTCCCTCGCGAACTCGGTGAAAGGAATTGGCGCCGTTCGACACcaggcggatccgctctgcagcacgaacccatctccagccgcagccgcagccgccgcccgggccgaggagcagccgcagcagccgccaccAGTGGCCGAGTGAGCGGAGCCGAGTTTGAGGCAGCGCCTAGCGGTGAATCGGGGCCCTCACCATGAGTTCCTCGCCTGTTAATGTAAAAAAGCTGAAGGTGTCGGAGCTGAAAGAGGAGCTCAAGAAGCGACGCCTTTCTGACAAGGGTCTCAAGGCCGAGCTCATGGAGCGACTCCAGGCTGCGCTGGACGACGAGGAGGCCGGGGGCCGCCCCGCCATGGAGCCCGGGAACGGCAGCCTAGACCTGGGCGGGGATTCCGCTGGGCGCTCGGGAGCAGGCCTCGAGCAGGAGGCCGCGGCCGGCGGCGATgaagaggaggaggaagaggaagaggaggaggaagGAATCTCCGCTCTGGACGGCGACCAGATGGAGCTAGGAGAGGAGAACGGGGCCGCGGGGGCGGCCGACTCGGGCCCGATGGAGGAGGAGGAGGCCGCCTCGGAAGACGAGAACGGCGACGATCAGGGTTTCCAGGAAGGGGAAGATGAGCTCGGGGACGAAGAGGAAGGCGCGGGCGACGAGAACGGGCACGGGGagcagcagcctcaaccgccggcgacgcagcagcaacagccccaacagcagcGCGGGGCCGCCAAGGAGGCCGCGGGGAAGAGCAGCGGCCCCACCTCGCTGTTCGCGGTGACGGTGGCGCCGCCCGGGGCGAGGCAGGGCCAGCAGCAGGCGGGAGGGGACGGCAAAACAGAACAGAAAGGCGGAGATAAAAAGAGGGGTGTTAAAAGACCACGAGAAGATCATGGCCGTGGATATTTTGAGTACATTGAAGAGAACAAGTATAGCAGAGCCAAATCTCCTCAGCCACCTGTTGAAGAAGAAGATGAACACTTCGATGACACAGTGGTTTGTCTTGATACTTATAATTGTGATCTACATTTTAAAATATCAAGAGATCGTCTCAGTGCTTCTTCCCTTACAATGGAGAGTTTTGCTTTTCTTTGGGCTGGAGGAAGAGCATCCTATGGTGTGTCAAAAGGCAAAGTGTGTTTTGAGATGAAGGTTACAGAGAAGATCCCAGTAAGGCATTTATATACAAAAGATATTGACATACATGAAGTTCGTATTGGCTGGTCACTAACTACAAGTGGAATGTTACTTGGTGAAGAAGAATTTTCTTATGGGTATTCTCTAAAAGGAATAAAAACATGCAACTGTGAGACTGAAGATTATGGAGAAAAGTTTGATGAAAATGATGTGATTACATGTTTTGCTAACTTTGAAAGTGATGAAGTAGAACTCTCGTATGCTAAGAATGGACAAGATCTTGGCGTTGCCTTCAAAATCAGTAAGGAAGTTCTTGCTGGACGGCCACTGTTCCCGCATGTTCTCTGCCACAACTGTGCAGTTGAATTTAATTTTGGTCAGAAGGAAAAGCCATATTTTCCAATACCTGAAGAGTATACTTTCATCCAGAACGTCCCCTTAGAGGATCGAGTTAGAGGACCAAAGGGGCCTGAAGAGAAGAAAGATTGTGAAGTTGTGATGATGATTGGCTTGCCAGGAGCTGGAAAAACTACCTGGGTTACTAAACATGCAGCAGAAAATCCAGGGAAATATAACATTCTTGGCACAAATACTATTATGGATAAGATGATGGTGGCAGGTTTTAAGAAGCAAATGGCAGATACTGGAAAACTGAACACACTGTTGCAGAGAGCCCCCCAGTGTCTTGGGAAATTTATTGAGATTGCTGCCCGAAAGAAGCGAAATTTTATTCTGGATCAGACAAATGTGTCTGCTGCTGCCCAGAGGAGAAAAATGTGCCTGTTTGCAGGCTTCCAGCGAAAAGCTGTTGTAGTTTGCCCAAAAGATGAAGACTATAAGCAAAGAACACAGAAGAAAGCAGAAGTAGAGGGGAAAGACCTACCAGAACATGCGGTCCTCAAAATGAAAGGAAACTTTACCCTCCCAGAGGTAGCTGAGTGCTTTGATGAAATAACCTATGTTGAACTTCAGAAGGAAGAAGCCCAAAAACTCTTGGAGCAATATAAGGAAGAAAGCAAAAAGGCTCTTCCACCAGAAAAGAAACAGAACACTGGCTCAAAGAAAAGCAATAAAAATAAGAGTGGCAAGAACCAGTTTAACAGAGGTGGTGGCCATAGAGGACGTGGAGGATTCAATATGCGTGGTGGAAATTTCAGAGGAGGAGCCCCTGGGAATCGTGGCGGATATAATAGGAGGGGCAACATGCCACAGAGAGGTGGTGGCGGTGGAGGAAGTGGTGGAATCGGCTATCCATACCCTCGTGCCCCTGTTTTTCCTGGCCGTGGTAGTTACTCAAACAGAGGGAACTACAACAGAGGTGGAATGCCCAACAGAGGGAACTACAACCAGAACTTCAGAGGACGAGGAAACAATCGTGGCTACAAAAATCAATCTCAGGGCTACAACCAGTGGCAGCAGGGTCAATTCTGGGGTCAGAAGCCATGGAGTCAGCATTATCACCAAGGATATTATTGAATACCCAAATAAAACGAACTGATACATATTTCTCCAAAACCTTCACAAGAAGTCGACTGTTTTCTTTAGTAGGCTAACTTTTTAAACATTCCACAAGAGGAAGTGCCTGCGGGTTCCTTTTTTAGAAGCTTTGTGGGTTGATTTTTTTTCTTTTCTTTTTTGTACATTTTTAATTGCAGTTTAAAAGTGAATCGTAAGAGAACCTCAGCATTGTGCACGATAAGAGAATGTGTCAGTATTTCAGGGTTCTACATTTTATCTGTAAAATGTGACTTTTTTTTTTTTTTATCACAACAGAAGTAAAATGTTGCTTTGTACCTGGTGTCTTTTATTAAGAATTTACTCCCCCCATTTCTCACAGAGAATAACAGTCGGGAGTCATTGTCACAATATAATAGAAATGTTAGCAACCAGATTCATGTAAGGACTAAGTGGTCCTCATGAATTGCATTAAGACTCTGTACTGCTCATATTACACTCCATCCTCTCTGTAGTTTGCTGGGTAGTGGAGGGGGTAAGCTAAATCATAGTTTCTGACAATAACTGGGAAGGTTTTTTCTTAAAATAACAATGGAATTGGTATAATTGGGATTGAAAACTAAAACTTGGAACTAAGATAGAGAAGATGGAGTGTATGTAGAAGGGCTGTTAAAAATGTAAAACTTGGTTGCATTATTTGTGGAGGCTCAAACTTGTGAAGGTTAATACCATAATTTTTCCATTTGTTCTGCATTTTGATTCTGAAAAGAAAGCTGGCTTTGCCCATTTCTTATTAAAAAAACTTGTTGTAAATCCAGTTGTCTAATGGGATCTATATGAAGTTAGCCATGTCTGTATGCCCTTCTCCCACAAAATACTGTATAACTAGTGTGCTTGTAGTAGTTAACTCCACCATCTTTGTAAGCTAATGAAATTGTGAGTCACCCATTTATATCTTAATTTTTAATCATGTCAGTTCTTGAATGGGTATCTCCTTAGCCTGCTGATTTCTTTTTCTTTCTAAAGAAAGTGGGTGGAGAAATTAATTTAGACGTTTGTTTGCAATAAAAAGAATTCATTTTACTCTTGTTTTGGGATTCTCGCCATCAAGGTTCAAAATCCCTTTATATAACTCCCAAGAGGAGAAATTTATTAAGTGTGTGCTTTCTGGACAGCTTATTCTTTACTCTGCATAGAACATTTAGGTTTTAAAAACTTAAATGTATACTGACAATTGATACATAATTATGAAGTAAAGTTGAATTCTTCCCTTCCCCTCCCCCCCAGACAACTTTTAACATATTTAATGAGGGGAAAAGGTACTGGCTGGGAGAAGTTAACACTGAGTTTATCATCTTTACAGAATGCTAATGCTGTCCTCAACTGATTATTTTATATACATATATATGATACATGAAACTCTGGGATCAGATGCTTTTAGAAGCCATCATGCAAGCCAGTCATTGATGTCACTGCTACACAACACTGCTAACTTGACTGTAGCTATGTAATAACATTAGATCCCCTAATTGTAATTATATTGGGTTTGCACAGAACACTTTAATCTTCCCCTCACCAATGTGAAGTGAGGAATCAGGAGTCAAACTGTAGAACTAAAATTTGACTTCAGTCTAGCGTTTCCTTGGTGTTTTTAGGTTGCTTTGGTAAGTTTAGGTTTGCTATATTTCTGATTGCTTAGAATTTTGTTTTAGCCCTTTAAAATCAGATCATAAATATGAATTCATACTTCTAAGGAATTTTCTTGCTATAAGCTGGAGTTTAGGTGATGTATAGGTTCAGTTGAGACATTTTTGGAACAGGCAAATCCTTAGTTAACATAAGATATTTAACAGTTGAAGATAGTGTCATGGATTTTTATCTTTTTTAGCAAGTAATGCTAAGAACCACTGGCCTGAGCTACTACTCTTCAGTATACATTATTAGGATTGCATAGACTTACTAGAGGAACAGTTTCAGGTTTTGATGCTAATCAGTGTTGTGTCCTAAAGTTGTCCTTTGTGCCTTTAAAAAGTTTTGGATATATCTTCTAGTTTAAAATTGCTTATTAAGGAATTCATTTTATAATTGCAGTGGGAAAGTAATGGTCAAGTAACACTAGGTAGACTATCATGCCTGTTTAGCCCAGAGAATTTGGGGGGAGAGAGAATAGATAAAAATGGCACCCAGAAAAATGTTAAAATCTTTAGTCAAGACTAGAATTAATACAATTGTCTACACTTGTATGGCAGAAATAACCTTATAAAGTGTTTAAGGAATTCAGAGAAGGGAATGTACCAAATAAGCAACAGGGAGAAAATTAGGTAAGAAGTAAGATACGAACGAGAAACCTGATTTATTGCTCATCCTTCCCTTGCCTCCCTAATGGCAAGCAAAACTCTGAACATCTGAAAAGGATGTAGTTCTGGACAAATCCTGACTACCCAGAGGAAACTCACTGTGAGATTGCTGTTGATTTGAAGGGTGCTTTCACTAAGGTTATATTTTAAAGTAGAATAACACATGCTGAGTGTAAACTGGCTTTGGATTGGTCAGCTGCAGTAGTACAAAAACAGCATAGAATTTGAGAAAACTAAAACTGCTATGAGATAGCTATGAGAAAACTAAAACTGCTATGAGATAGAAATGATGTAAAATTATGTGGAAAGTTTTCCCTCATATACTCACATACAGCCTTTGAAGGGCTCTGGCTCTGACCGGTTGATGGCCTTGAGCGAGATGAAATCATGAAATTGAGTCAAATCAATTTGACATTGAAATGACAAGAGGAAACTCTTAAATACATAAAAACAAGCTCTCATTTGCCTAGGATAGATACTGTCTTAAAAATAAAGACTGAACCTAGATGTTCTGAGCACTAGCAACAAGGTATTTTAACAAGTTTAAAGGAATTCTCTGAAAAAGTTATAAAATTATTCTAGGAAACATAACCATAATAGTGTTTTAAGGGACTTTCACCTGGGGATTTTATATTCATGAACAGAGTGTATTCTGTATTTAAAATGTCTCATTTGTGGGAATTGGATGACATGTTTTTTGATAAATTTATTCACAATATAAATTGACTTTTTATTCTAGGACCATGTGAATAATGGGTTCCATTGCACAAATACAAATATTTTAATAGCTTCTTAGGCAGTGGTGTAGACATCTTGGATATAAATAATTGTAGATCTTGTATATTTGATTTTTAAAAAACTAGAATAAACAGAGAGGCATAAACATATCTTAGAGTCCAAGTGGTAGTGTTTAGCATTGGATATAATAAATGGATGTTTTACAAAGTGTTTCCATAATTCTCTTCCTATACATAAATGTCTTGTTTTCAAAAGTGGATGGAACTTggctgggtgtggtggctcacgcctgtaatcctagcactttgggaggccaaggcgggaggatcacttgagctcaggagtttgagaccatcctgggcaacatagtgagacctggtctcttgaaaaaaaaaaaGTGGATGGAACTTGTAGCAGAGAATTTTATCTACTTCTCAACCTGCTTCAGAATACCCATTTGAGATGTTCCCCTGGAAAGATGAACACAATACTGCATCTGAAGCCATTTCTTCCCACCTAACATTCTTAAAATGATTAGAGTCTAAACTTTGTCATTCATTCCTAATTCTGGAGCTCTGAGGTTGAGGTGTTCAGAGTTTGGTGAATAATTGGGTTTAAGTTTTAACATTTTAGTAATAATAAAAGCAAACACATACATGTTAAGGCCTGACAATAGGTTGCAATACCCATGCATTGGGACTCATACCCAGCATAAATGGTGAGGGACTGAACATTAGTGCTTTGAGCAAGAATTGGTTAACTACCTGAGATCTCTAAAACAGTAATTTGAATTACTAATACATAAACCACAAGTCTCTTCGAATTGTTAATTGCCTAAATTTACCCTAAAACTTAGTTAACGCTGCAGTGCCTTTATTAAAGCTTTTTTTTGGGGGGGGGTGTGGGCACAGCTACTCCATAACTTTAAATTTTAAAGCATGAAGGTGATCTAGCTAGTGTTAGTGCTTGAGTTGGTAGTTACATAGGCTGCTCTTGAATCGTCCTGTTTTCTTTGCCTAGTATTAGCACCACAGGTACATATTTGTAAAATAAGCATTAAAAGTACTTTGTCCAGC

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