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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CENPWP1
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Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:53023407-53023590  UCSC
Coordinates (T2T) chr14:47231380-47231563  UCSC
Coordinates (hg19) chr14:53490125-53490308  UCSC
Strand +
Parental Sequence NM_001012507.4
Parental seq. overlap 158 bp
Parental seq. overlap (%) 19.5%
Genomic Region Intergenic
Retrocopy Summary CENPWP1, located on chr14:53023407-53023590, is a retrocopy of the parental gene CENPW. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CENPW
Full Name centromere protein W
Also known as C6orf173|CENP-W|CUG2
Coordinate chr6:126339696-126348875
Strand +
Gene summary Predicted to enable DNA binding activity and protein heterodimerization activity. Involved in chromosome segregation; kinetochore assembly; and mitotic cell cycle. Located in kinetochore and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CENPWP1
Bonobo Pan paniscus CENPWP1
Gorilla Gorilla gorilla CENPWP1
Orangutan Pongo abelii CENPWP1
Gibbon Nomascus leucogenys CENPWP1
Green monkey Chlorocebus sabaeus CENPWP1
Crab-eating macaque Macaca fascicularis CENPWP1
Rhesus Macaca mulatta CENPWP1
Baboon Papio anubis CENPWP1
Golden snub-nosed monkey Rhinopithecus roxellana CENPWP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>CENPWP1
AAGTCTTCAAGTAACAGAAGCCTCACCTTCATATGGAGACAAGTGGTGAGTTACTGGCCCATCTGAATGACTTACTGTTTGTTCATTGATTAGCAGAAGAGTCCAGGACAAATGCCTGTGAGAATAAATGTGGAGTCATCAAAAAGGAGCATGTACCGGCTGCAGCACAGGGAATTCTACAGAA
>NM_001012507.4
GTTCCGTTGGCGGCGGATTCGAACGTTCGGACTGAGGTTTTTCTGCCTGAAGAAGCGTCATACGGACCGGATTGTTTTCGCTGGCCCAGTGTCCCCGGAGCTTGTGTGCGATACAGAGAGCACCTCGGAAGCTGAGGCAGCTGGTACTTGACAGAGAGGATGGCGCTGTCGACCATAGTCTCCCAGAGGAAGCAGATAAAGCGGAAGGCTCCCCGTGGCTTTCTAAAGCGAGTCTTCAAGCGAAAGAAGCCTCAACTTCGTCTGGAGAAAAGTGGTGACTTATTGGTCCATCTGAACTGTTTACTGTTTGTTCATCGATTAGCAGAAGAGTCCAGGACAAACGCTTGTGCGAGTAAATGTAGAGTCATTAACAAGGAGCATGTACTGGCCGCAGCAAAGGTAATTCTAAAGAAGAGCAGAGGTTAGAAGTCAAAGAACATATTCTTGAAAGTTATGATGCATTCTTTTGGGTGGTAACAGATCATAAAGACATTTTTTACACATCAGTTAATATGGGATTATTAAATATTGGCTATAAGTGATGTGTGTGTTTGTATTTTTTTTCTGGCATGAAATATCTCAAGTAAATGCATAGGACTATTTAACCCTTTTATGGGAATTACTATTATTTTTATTTTAAATGTCCTCTAGTTCAGTTTGCTTTTGTTTTGTTGCTGCTGCAAATATTTTATGTATCAAAAATGAAATCTTACTATATTAAATACTTTGAAAATGTACTTCTTAGAATTAAGTTTATATATATTTAGATTTAGCCACAGTTAACTATGGAATTTAATCTCTGAAGAAAG

Publications

PMID - Link Title
No publications available for this retrocopy