Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BLZF2P
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:68866658-68868952  UCSC
Coordinates (T2T) chr14:63075672-63077962  UCSC
Coordinates (hg19) chr14:69333375-69335669  UCSC
Strand -
Parental Sequence NM_001320973.2
Parental seq. overlap 1382 bp
Parental seq. overlap (%) 50.7%
Genomic Region Intergenic
Retrocopy Summary BLZF2P, located on chr14:68866658-68868952, is a retrocopy of the parental gene BLZF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BLZF1
Full Name basic leucine zipper nuclear factor 1
Also known as GOLGIN-45|JEM-1|JEM-1s|JEM1
Coordinate chr1:169368195-169396575
Strand +
Gene summary Enables ubiquitin protein ligase binding activity. Acts upstream of or within Golgi organization and Golgi to plasma membrane protein transport. Located in Golgi apparatus and nucleoplasm. Biomarker of hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BLZF1P1
Bonobo Pan paniscus BLZF1P1
Gorilla Gorilla gorilla BLZF1P1
Orangutan Pongo abelii BLZF1P1
Gibbon Nomascus leucogenys BLZF1P1
Green monkey Chlorocebus sabaeus BLZF1P1
Crab-eating macaque Macaca fascicularis BLZF1P1
Rhesus Macaca mulatta BLZF1P1
Baboon Papio anubis BLZF1P1
Golden snub-nosed monkey Rhinopithecus roxellana BLZF1P1
Marmoset Callithrix jacchus BLZF1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BLZF2P
GAGCCATCATAAATACCCATTGATTGGCCTTTAAGAATAATTACAAAATATTTATATCAAATTATGCAAATTTGTTGCAGAAGTGCCTATCAGTAGAGAAGTCTTCAAAAGACAAACCTGGTCAAATAATAATATATTTTAATGTCAACACTCTAAAGTAATTGTAGTAGAAGGCCAGAGGGCTTTCTTTCCCTTTATGGTAATTTTTTGAGCTACAAAAGAGCCTTGGATAAGTGAATGAAGGGATTAATCTTTTTAAAATAAATGCTGTAAGTTAGAAAAAGAATAAATATTTTAGAGCCAAATTAACAAGTACTTCAGCAAAACATGTTAGTTTTATGCAGGGGATTCTGTATTCTGAATGGACACAATCTGACATAGATAAACAGATTCTTAACTGTTGACTCTTTAGCAAATGCAACACACAGGAATATCCATTTGATATTTATAAAAAGTAGACTGTTTCTAAAACATTGTATAAGCTCAAAGAAAAAAATGCAACCCATCAATGTCAAAAACGTGATGCACGTGGGGCCATACAGGATCTCCTAAGTGAATGGGAACAGTTTCTTCAGGAAATGATAGCTACCCAGAAATTATTGGAGGAGCTCTTAGTCTCCTTGCAGTGGGGAAGAGGGCAACTTTACTCCCCTAATGTACAACCCCACAGCACAGCAGAGCTGGCATTAACAAATCACAAGTTGGCAAAAGCAGCAAATTCTCATCTTCTGCGAAACGTTGGCATTAACTATCAAAAAAAGATTCCATCGACAGTTGAATTCTGCAGCACCCCAGCTGAGAAAATGGCTGAAATGGTTCTATAAACTTTAGATCCAACTACCTATACAGAGAGCTCACCTGATAATCCATGTTTTGAGTTTTCACCAACCACCTTACTTGCTGCAAAGAAAAATTCTGGATGATTTCATCCCTAGGCTAGATATGAAAATATAACTTTCAATTTCTGCAGTCACTGCCAGGGAGAACTTACTGCCCTTTAACAGTCAATATATTGGAGGCATGCTACAGGTACTTGCTTATTACCCGAGAGTCATTATTTGGGAGCTGGGGTTCTTAGAATGCTAGAAGTAATATCACTTCCTATTTACAAAGTGTATATACCCAAAGATGTTTTATGTACTAGACTCCAGATTACCCCTTCTTAATAAATATCTCAGGGTAATAAAAGAATGAAACTGTATTTAAAATTTAAATACAGTTGCATTTTTTTTCTTTGAGCTTATACAATGTTTTAGAAACAGTCTACTTTTTATAAATATCAAGTTGGATATTCTTGTGTGTTAAACTGTATTTAATATTTAAAATAGAGAATACTTCCCAAGCAATACATGATGCTTTTCCTAAAGGACTCTAAAAGTAAAAGGTTCTATAACTTTCTTTTAAGCACTAAATTATTATTTATCTTACTGGATATTTTATATGAACAGTGTTAATTTAGTTACACTAAAGCAAGGGTAGGCAAACTACAACCATGAGTCAGCTCAAGAATTATGAAAGAAGGTTACTACAGGACAAAGAAGGTCTTTGAAACCAGCTCTGTATACAGAAGGAGGTAAATCATGAGATTAAAAAGTTGCTGATGGCTTCTGTTGGGGATGATCTTCAGTATCACTTTGAATGTCTAGTCCTTGAGAAAAATCAGCTTATTTTAGAAAATGAAGCCCTAGGTTGAAATACAGCTCAGCTTTCCAAACAGAACGTATGTCAATACAGTGTGATACATGGCAAAGTAAATTCCTTGCAAGCAGGGTAATGGCAGATGAGTTAACCAAGTCAAGAGCATCAAGAGCAG
>NM_001320973.2
AGGAGTGAGAGAGCTGCTGGATATGCGGAGGGACTGGGCGGGTCGGCTTCCGAATGGAAGAGGTCTGTGAGAAGTTAACCTGGTGATACCGATCCGAAGAGCCTATCAAGTGAAGCCCCCTGAAATACGGAGAATAAGAATCTTAGAGGTTGTTCAGCAGAAGTCTTGGAGTGCATTTTCAGTGGTTAAGGTGAAAAAATGACTACTAAAAATTTAGAAACCAAAGTCACCGTTACTTCATCCCCAATCCGAGGAGCAGGAGATGGAATGGAAACTGAGGAACCACCTAAATCTGTTGAAGTTACCTCCGGAGTCCAATCTAGAAAGCATCATAGTCTTCAGAGTCCATGGAAGAAAGCAGTTCCATCAGAGAGCCCAGGAGTTCTTCAGCTAGGGAAAATGCTCACTGAAAAAGCAATGGAAGTTAAAGCTGTAAGAATATTAGTTCCCAAAGCTGCTATAACTCATGATATCCCCAACAAAAATACAAAGGTTAAGTCTCTGGGACATCATAAAGGAGAATTCCTTGGTCAGTCAGAGGGAGTTATAGAACCTAATAAGGAACTCTCAGAGGTAAAGAATGTATTGGAAAAGCTCAAGAATTCTGAAAGAAGGTTACTACAGGACAAAGAAGGTCTTTCAAACCAGCTCCGTGTACAGACAGAGGTAAATCGTGAGTTAAAAAAGTTACTGGTGGCTTCTGTTGGGGATGATCTTCAGTATCACTTTGAACGTCTAGCCCGTGAGAAAAATCAGCTTATTTTAGAAAATGAAGCCCTAGGTCGAAACACAGCTCAGCTTTCTGAACAGTTAGAACGTATGTCAATACAGTGTGATGTATGGCGAAGTAAATTCCTTGCAAGCAGGGTAATGGCAGATGAGTTAACCAACTCAAGAGCAGCTTTACAGCGTCAAAACCGTGATGCACACGGGGCTATACAAGATCTCCTAAGTGAACGGGAACAGTTTCGTCAAGAAATGATAGCTACCCAGAAATTATTGGAGGAGCTCTTAGTTTCCTTGCAATGGGGAAGAGAGCAAACTTACTCCCCTAGTGTACAACCCCACAGCACAGCAGAGCTAGCATTAACAAATCACAAGTTGGCAAAAGCAGTAAATTCTCATCTTCTGGGAAATGTTGGCATTAACAATCAAAAAAAGATTCCATCAACAGTTGAATTCTGCAGCACCCCAGCTGAGAAAATGGCTGAAACGGTTCTAAGAATTTTAGATCCAGTTACCTGCAAAGAGAGTTCACCTGATAATCCATTTTTTGAGTCTTCACCAACCACCTTACTTGCTACAAAGAAAAATATTGGACGATTTCATCCCTATACTAGATATGAAAATATAACTTTCAATTGCTGCAATCACTGCCGGGGAGAACTGATTGCCCTTTAACAGTCAATATGTTGGAGGCATGCTAAGGTACTTCCTTATTACCCAAGAGTCATTATTATTTGGGAGCTGGGGTTCTTACAATGCTAGAAATAATATCACTTCCTATTTACATAATGTATACACCCAAAGATATTTTATGTACTAGACTCCAGATTACCCTTTCTTAATAAATATCTCAGGGTAAGGAAAGAAAGAAACTGTATAGATATATTTAAAATAGAGAATACTTTCCAAGCAATACATGATACTTTTCCTAAAAGACTCTAAAAGAAAAAGATTCTGTAACTCTCTTTTAGCACCAAATTATTGTTTATCTTGCTGGATATTTTATATGAACAGTGTTAATTTAGATGCACTAAAGCAAAGGTAGGCAAACTACAACCATGAGTCAaacatggccacacccattcatgtgctattgtctaagctggttttgcactacaactgcagagttgaatagatgcagcagaTCCTTTACAGAAAAAGTTTTCTGACCTCAATTCTAAAGTAATTGTAGTAGGGAGCTGGAGGACTTTCTTTCCCTTTATGGTAATTTTTTGAGCTACAAAAGAGCCTTGCAGAAATGGGTGAAGGGATTAATCTTTTAAAAATAAATGCTATATATTAGGAAAATAAAAAATATTTTAGAGCCAAGTTAACAAGTACTTCAGCAAAACATGCTAGTTTTATGCAGGGGATTCTGTATTCCAAATGGATACAATCCGACATATATAAAAGAAACAGATTCTTAACTATTGACTCTTATTTAGCAAATGCAACAGACAAGAATATCCAACTTGATATTTATAAAAGGTAGACTTTTTCCAAAAGTGTATAAGCTCAAAGAAaaaatgcaacctgtcaattaatatatactatgtaatatatattatTGTGTATTTATGATTAGCCATCATAAATGCCCATTGCTTGGCCTTTAAGAATAATCACAAAATATTTATATTAAATTATACAAATTTGTTGCAGAAGTGCCTGTGAGAGAAATCTTCAAAAGACAAACCTGGTCAAATAATAATAATTTTAATGTCAATGATTTTTTTTGTCTGACTCATCTGAGTTATATTTAGTTTTCAAGTGGCAATAAATTTATCTACCTTCTTTA

Publications

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