Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZMYND19P1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr14:77696758-77697697  UCSC
Coordinates (T2T) chr14:71906113-71907052  UCSC
Coordinates (hg19) chr14:78163101-78164040  UCSC
Strand +
Parental Sequence NM_138462.3
Parental seq. overlap 780 bp
Parental seq. overlap (%) 55.7%
Genomic Region Intragenic (ALKBH1)
Retrocopy Summary ZMYND19P1, located on chr14:77696758-77697697, is a retrocopy of the parental gene ZMYND19. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZMYND19
Full Name zinc finger MYND-type containing 19
Also known as MIZIP
Coordinate chr9:137582079-137590512
Strand -
Gene summary ZMYND19 is a MYND zinc finger domain-containing protein that binds to the C terminus of melanin-concentrating hormone receptor-1 (MCHR1; MIM 601751) (Bachner et al., 2002 [PubMed 12208518]), and to the N termini of alpha-tubulin (TUBA1; MIM 191110), and beta-tubulin (TUBB; MIM 191130) (Francke et al., 2005 [PubMed 16039987]).[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZMYND19P1
Bonobo Pan paniscus ZMYND19P1
Gorilla Gorilla gorilla ZMYND19P1
Orangutan Pongo abelii ZMYND19P1
Gibbon Nomascus leucogenys ZMYND19P1
Green monkey Chlorocebus sabaeus ZMYND19P1
Crab-eating macaque Macaca fascicularis ZMYND19P1
Rhesus Macaca mulatta ZMYND19P1
Golden snub-nosed monkey Rhinopithecus roxellana ZMYND19P1
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZMYND19P1
AAAGACCAAATACGCTGACAGATGAGCAAAGATATCCTGCTGGTGGAGGGATACTCCTCTGAGGTCCAAATGGAAGTAGATGCAGATAGAAATGGTACTAAGATATTCAGGTATGCTTTTGACAAGCACTGAGGAAGAGGATTGGGAAGACTCCTTCATGAGTTGCTGTGGGAGCACAGAAGAGGCATGACCCCTGGGTTCCAGGCGGTACGTCTCAATGCCCTGACTGAGACAATTGCCTGGACAACCTGTAGCTGGTGCTGTGGGGCTGGTGGCCCAAAGCCAAAGAGACCTCCAGAAGAGGTAGCAAAGCTTGTACTGGTTTGCAATTCAGCAGCTTCCCATGGACCCCAAAGAAGAGCAGTGACCTGTCCTAACTGTGACCTGGTACTGTAACACCAATGGAGACGTGGTGGAAGAGTTGAATTCTTACACCTACTATAGCAGCATTACCCTTCCTGCACAGTGATTGAGAAGTAGCTCCAGGAGTTCAAAATCTGTGGGTGCTGCCAGGTGGCCCAGTACTGAGGCTCTGAGTGCCAGCAGGAGCGGGCTGGCCACCATGAAGCACTGTCAGGAGAGGAAGCACCCCTTCCAGCATGACCTCAGCTGGAGCAATGACGGGCAATGGAGCTGCACATGCTCGCAGTCCCTGGGCTCTACCTTGGACACAGCAGACAGACTGGTGGTTGAACTTGGAGGTGTTGAAAAAGCCAGCTGTGGGCCCAGAACAGCCACCAAGTGACTCTCGATGTCACTGGAAGTGTGTATGAAGATAGCGTCCCCTCCAGTCTTAATCTCCAGCAAAGACAACCGGGAGACTCTGGCCAGGATGTTTCTCATTATTTATACGTTAATAGGTTTGTAAATTCATGTGCAGGTTTTTTGGGAGGAGGCACTGAGTGGGGTAGAAATTACAAATAAAATCATTTGCTGT
>NM_138462.3
GCTCCGCTCGCTGTGGTgcgcgcggtggcggtggcggcggcggcggcggcgcgtggcaggtccggcgggcgcgaggcggcggcggaggcCCGAGCCCGGCCCAGCCTCGTCCCGCCCGGAGCCCGCCTGGCTGCTACCCCGACCCCGGCTCCGGTCCCGTCCTGTCCCGGCGCGCCGCGGCCTCGCCCCGGCCCCCGCTCGGCGCCTCCCGAGGGAGCGGCGCTGCCGGCCGAGAGCGCAGGCCCGGCCATGACCGACTTCAAATTGGGTATCGTGCGGCTCGGCCGGGTGGCCGGGAAGACCAAATACACGCTGATCGATGAGCAGGACATCCCGCTGGTGGAGAGCTACTCCTTTGAGGCCCGAATGGAAGTGGATGCAGATGGAAATGGTGCTAAGATATTTGCCTATGCCTTTGACAAGAACCGAGGAAGGGGCTCTGGGAGACTCCTTCATGAGCTGCTGTGGGAGCGGCACCGGGGGGGCGTGGCCCCGGGCTTCCAGGTGGTGCACCTCAACGCTGTGACCGTGGACAATCGCCTGGACAACCTGCAACTGGTGCCGTGGGGCTGGCGGCCCAAGGCTGAAGAGACCTCCAGCAAGCAGAGGGAGCAAAGCTTGTATTGGCTTGCAATTCAGCAGCTGCCTACAGACCCTATAGAAGAACAGTTTCCTGTCCTAAATGTGACCCGGTATTATAATGCCAACGGGGATGTAGTGGAAGAGGAGGAGAACTCTTGCACCTACTATGAGTGCCACTACCCTCCCTGCACAGTGATTGAGAAGCAGCTCCGGGAGTTCAACATCTGTGGGCGCTGCCAGGTGGCCCGGTACTGCGGCTCCCAGTGCCAGCAGAAGGACTGGCCTGCCCACAAGAAGCACTGTCGGGAGAGGAAGCGTCCCTTCCAGCATGAGCTTGAGCCAGAGCGATGACGGGCAGGGGAGCCACACATACTCACAGCCCCCGGGCTCTACCCTGGGCACAGCAGAGACAGACTGGTGGTTGAACCTGGAGGTGCCAAAAAAGCCAGCTGCGGGCCCAGGACAGCTGCCGTGAGACTCCCGATGTCACAGGCAGTCTGTGTGGTTACAGCGCCCCTCAGTGTTCATCTCCAGCAGAGACAACGGAGGAGGCTCCCACCAGGACGGTTCTCATTATTTATATGTTAATATGTTTGTAAACTCATGTACAGTTTTTTTTGGGGGGGAGGCAATGGGAAGGGTAGAAATTACAAATAGAATCATTTGCTGTAATCCTTAAATGGCAAACGGTCAGGCCACGTGACTAAAAACTGTCCTGTTGTCGAAGCTTCTCCCCTGGGCCGCCGGGAGCCCCGTGGAGCGCGGCCTGCACGGGAGTTGTGTCCACAAAGGCAAAGTAAAGGGGTGGAATCA

Publications

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