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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TOMM5P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:51197234-51197638  UCSC
Coordinates (T2T) chr1:51077144-51077548  UCSC
Coordinates (hg19) chr1:51662906-51663310  UCSC
Strand +
Parental Sequence NM_001001790.3
Parental seq. overlap 346 bp
Parental seq. overlap (%) 48.3%
Genomic Region Intergenic
Retrocopy Summary TOMM5P1, located on chr1:51197234-51197638, is a retrocopy of the parental gene TOMM5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TOMM5
Full Name translocase of outer mitochondrial membrane 5
Also known as C9orf105|Tom5|bA613M10.3
Coordinate chr9:37588413-37592597
Strand -
Gene summary Predicted to be involved in protein targeting to mitochondrion. Located in mitochondrion. Part of mitochondrial outer membrane translocase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TOMM5P1
Bonobo Pan paniscus TOMM5P1
Gorilla Gorilla gorilla TOMM5P1
Orangutan Pongo abelii TOMM5P1
Gibbon Nomascus leucogenys TOMM5P3
Marmoset Callithrix jacchus TOMM5P2
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TOMM5P1
AAGGCAGCCACTGAGGAGAGCAGAGTGCAGCAGCTGAAGGCTGGTGAGTCAGAGCCATGATGTTCTGGATTGAGGGCCTCACACCGAAGCTGGACCTGGAGGAGATGAAACAGAACAGAAGACATGCAAAGATGTGATCTCCTCCATACTGAACTTCCTCAGCTACATGGCCCTACTGCAAGTCACTCCTTTTATCTTAAAGAAATTGGACAGCATATGAAGATTGGGCATCATGTGTGAATGCATAATACGAAGAATCTGGCTACAGTTTCTACTCCTCTCTGCAAGTGAAAAGGCCCAGAAAGGTGTAAGAGACCCTTTGAATGGACATATTCAACAAATTCTGCTTGTTAAGAACAACTTTGGCTCTGGTAACTGACCTTCGTAGCTAAAATATAAAACTAT
>NM_001001790.3
GGGCGCGAGGCGGCCACCGTGGAGAGCAGAGCGCGGCGGCTGGAAGCTGCTAAGTCAGAGCCGCGATGTTCCGGATTGAGGGCCTCGCGCCGAAGCTGGACCCGGAGGAGATGAAACGGAAGATGCGCGAGGATGTGATCTCCTCCATACGGAACTTTCTCATCTACGTGGCCCTCCTGCGAGTCACTCCATTTATCTTAAAGAAATTGGACAGCATATGAAGACAGGACATCACATATGAATGCACGATATGAAGAGCCTGGTTACAGTTTCGACTCCTCTCTGCAAGTGAATAGGCCCAGAAAGGTGTAAGAGACTCTTTGAATGGACATAAAATTCTGCTTGTTAAGAACAAGTTTGGCTCTGGTAACTGACCTTCAAAGCTAAAATATAAAACTATTTGGGAAGTATGAAACGATGTCTCGTGATCTGGTGTACCCTTATCCCTGTGACGTTTGGCCTCTGACAATACTGGTATAATTGTAAATAATGTCAAACTCCGTTTTCTAGCAAGTATTAAGGGAGCTGTGTCTGAAATGGCACTGTCTTGTCAGTCATTTCTGTTTACCTTTTTCTTCTGCCCAGAGTGTATTTGTGAAGAGTCTCTTATATTATGTTTTGTGGAAATCAGCACACAACCACAATGACATTTAAGCACAGGATCATTATTAGTCTATGTTTTTAATAAACATATCAATTAAGAAAA

Publications

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