Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SYNGR2P1
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:30044722-30046080  UCSC
Coordinates (T2T) chr15:27836449-27837807  UCSC
Coordinates (hg19) chr15:30336925-30338283  UCSC
Strand +
Parental Sequence NM_004710.7
Parental seq. overlap 1307 bp
Parental seq. overlap (%) 87.4%
Genomic Region Intergenic
Retrocopy Summary SYNGR2P1, located on chr15:30044722-30046080, is a retrocopy of the parental gene SYNGR2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SYNGR2
Full Name synaptogyrin 2
Also known as -
Coordinate chr17:78168545-78172964
Strand +
Gene summary This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SYNGR2P2
Bonobo Pan paniscus SYNGR2P2
Gorilla Gorilla gorilla SYNGR2P2
Orangutan Pongo abelii SYNGR2P2
Gibbon Nomascus leucogenys SYNGR2P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SYNGR2P1
AGTCTTCGCCTTGATCGTGTTCTCCTGCATCTATGGCGAGGGCTACAGCAACACCCATAAGTCTAAGCAGATGTACTGCGTGTTCAACCACAACGAGGATGCCTGCCGCTATGGCAGTGCCATCGGGGTGCTGGCCTTCCTGGCCTCGGCCTTCTTGGTGGTCGACGCGTATTTCCCCCAGATCAGCAACGCCACTGACCGCAAGTACCTCGTCATTGGTGACCTGCTCTTTTCAGCTCTCTGGACCTTCCTGTGGTTTGTTGGTTTCTGCTTCCTCACCAACCAGTGGGCGGTCACCGACCCGGAGGACGTGCTGGTGGGGGCCGACTCTGCGAGGGCAGCCATCACCTTCAGCTTCTTTTCCATCTTCTCCTGGGGTGTGCTGGCCTCCCTGACCTACCAGCGCTACAAGGCTGGCGTGGACGACTTCATCCAGAACTACGTCGACCCCAGTCCGGACCCCAACACTGCCTACGCCTCCTACCCAGGTGCATCTGTGGACAACTACCAACAGCCACCCTTCACCCAGAATGCGGAGACCACCGAGGGCTACCAGCCGCCCCCTGTGTACTGAGTGGCGGTTAGGGTGGGAAGGGGGACAGAGAGGGCCCTCCCCTCTGCCCTGGACTTTCCCATGAGCCTCCTGGAACTGCCAAACCCCCTCTTTCACCTGTTCCATCCTGTGCAGCTGACACACAGCTAAGGAGCCTTACAGCCCGGCGGGGGCTGGCCGAGCCACACCCCACGTGCCTGTGCCCAGAGGGCTTCAGTCAGCCGCTCACTCCTCCAGGGCACTTTTAGGAAAGGGTTTTTAGCTAGTGTTTTTCCTTGCTTTTAATGACCCCATCCCCGCCTGGAGTGGCTAGAAGCCAGCAGGCACCCATGTGCTACTGACAAGTGCCTCAGCTTCCCCCCGGCCCGGGTCCGGCCGTGGGAGCCGCTGTTACCTGCGTTCTCTGCCAAAGACTCGTGGGGGCCGTCACACCTACCCTGTGCAGCGGAGCCGGACCAGGCTCTTGTGTCCTCACTCAGGTTTGCTTCCCCTGTGTCCACTGCTGTATGATCTGGGGGCCACCACCCTGTGCCGGTGGCCTCTGGGCTGCCTCCCACGGTGTGAAGGCGGGGCTGGTGCTCATGGCACTTCCTTCTTGCTCCCACCCCTGGCAGCAGGGAATGGCTTTGCCTGACAACACCCAGCTTTATGTAAATATTCTGCAGTTGTTACTTAGGAAGCCTGGGGAGGGCAGAGGTGTCCCATGGCTCCCAAACTCTGTCTGTGCCGAGTGTATTATAAAGTCGTAGGGGAGATGCCCGGCCCTGGGATGCTGTTTGGAGATGGAATAAATGTTTTCTCATTCA
>NM_004710.7
GCGTTCCgcggcggcggcagcggcggcgacggcgacatggagagcggggcctacggcgcggccaaggcgggcggcTCCTTCGACCTGCGGCGCTTCCTGACGCAGCCGCAGGTGGTGGCGCGCGCCGTGTGCTTGGTCTTCGCCTTGATCGTGTTCTCCTGCATCTATGGTGAGGGCTACAGCAATGCCCACGAGTCTAAGCAGATGTACTGCGTGTTCAACCGCAACGAGGATGCCTGCCGCTATGGCAGTGCCATCGGGGTGCTGGCCTTCCTGGCCTCGGCCTTCTTCTTGGTGGTCGACGCGTATTTCCCCCAGATCAGCAACGCCACTGACCGCAAGTACCTGGTCATTGGTGACCTGCTCTTCTCAGCTCTCTGGACCTTCCTGTGGTTTGTTGGTTTCTGCTTCCTCACCAACCAGTGGGCAGTCACCAACCCGAAGGACGTGCTGGTGGGGGCCGACTCTGTGAGGGCAGCCATCACCTTCAGCTTCTTTTCCATCTTCTCCTGGGGTGTGCTGGCCTCCCTGGCCTACCAGCGCTACAAGGCTGGCGTGGACGACTTCATCCAGAATTACGTTGACCCCACTCCGGACCCCAACACTGCCTACGCCTCCTACCCAGGTGCATCTGTGGACAACTACCAACAGCCACCCTTCACCCAGAACGCGGAGACCACCGAGGGCTACCAGCCGCCCCCTGTGTACTGAGCGGCGGTTAGCGTGGGAAGGGGGACAGAGAGGGCCCTCCCCTCTGCCCTGGACTTTCCCATGAGCCTCCTGGAACTGCCAGCCCCTCTCTTTCACCTGTTCCATCCTGTGCAGCTGACACACAGCTAAGGAGCCTCATAGCCTGGCGGGGGCTGGCAGAGCCACACCCCAAGTGCCTGTGCCCAGAGGGCTTCAGTCAGCCGCTCACTCCTCCAGGGCACTTTTAGGAAAGGGTTTTTAGCTAGTGTTTTTCCTCGCTTTTAATGACCTCAGCCCCGCCTGCAGTGGCTAGAAGCCAGCAGGTGCCCATGTGCTACTGACAAGTGCCTCAGCTTCCCCCCGGCCCGGGTCAGGCCGTGGGAGCCGCTATTATCTGCGTTCTCTGCCAAAGACTCGTGGGGGCCATCACACCTGCCCTGTGCAGCGGAGCCGGACCAGGCTCTTGTGTCCTCACTCAGGTTTGCTTCCCCTGTGCCCACTGCTGTATGATCTGGGGGCCACCACCCTGTGCCGGTGGCCTCTGGGCTGCCTCCCGTGGTGTGAGGGCGGGGCTGGTGCTCATGGCACTTCCTCCTTGCTCCCACCCCTGGCAGCAGGGAAGGGCTTTGCCTGACAACACCCAGCTTTATGTAAATATTCTGCAGTTGTTACTTAGGAAGCCTGGGGAGGGCAGGGGTGCCCCATGGCTCCCAGACTCTGTCTGTGCCGAGTGTATTATAAAATCGTGGGGGAGATGCCCGGCCTGGGATGCTGTTTGGAGACGGAATAAATGTTTTCTCATTCA

Publications

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