Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PRELID1P4
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:35121041-35122241  UCSC
Coordinates (T2T) chr15:32926378-32927578  UCSC
Coordinates (hg19) chr15:35413242-35414442  UCSC
Strand -
Parental Sequence NM_013237.4
Parental seq. overlap 760 bp
Parental seq. overlap (%) 50.8%
Genomic Region Intergenic
Retrocopy Summary PRELID1P4, located on chr15:35121041-35122241, is a retrocopy of the parental gene PRELID1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PRELID1
Full Name PRELI domain containing 1
Also known as CGI-106|PRELI|PX19|SBBI12
Coordinate chr5:177303799-177306949
Strand +
Gene summary This gene encodes a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PRELID1P7
Bonobo Pan paniscus PRELID1P8
Gorilla Gorilla gorilla PRELID1P7
Orangutan Pongo abelii PRELID1P6
Gibbon Nomascus leucogenys PRELID1P2
Green monkey Chlorocebus sabaeus PRELID1P5
Crab-eating macaque Macaca fascicularis PRELID1P3
Rhesus Macaca mulatta PRELID1P3
Baboon Papio anubis PRELID1P3
Golden snub-nosed monkey Rhinopithecus roxellana PRELID1P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PRELID1P4
TTTGTGTAGCCAGCCCATCACCACCACAGCTCCCCAGACAGTTGGCTTAGCCCCTCTGCCCTCCCTCCATTGTACTTTATCATTAAAAATCAACTTCCAGCCCTATCTACTGTCTGGGCGGTGGGTTGTGGGGAATCCAGTTTGACATCTGCAGTACACCAGGCACGTGATCCACGTTTGAGCCACGTCTGCTTATTCTCCCATTGGGCAGCTGCAGACCGAGGAACAGAGGGGCAGTGACTTGACCCGGGCTCCAGGTAGCCTGCAGGTAAACTGGCACTAAGTGGGCGGCGGCAGCGGCAGCTGTTTGGGCGCGGTGCGGTGGTGACTGAGCTACGAGCCTGGCGGCGGGTGCGCGCCGAGCCCCGGCCCGGCCCCCGCGTGCCTCCCAGGCTCCACACCCCTGATGCTGAGCGGGTGCTGAGCCCGCTCCGGCCGGGACGATGGTGAAGTATTTACTGGGCCAGGGCGTGCTCCGCAGTTCCTGGGACCAAGTGTTCGCCGCCTTTTGGCAGCGGTACCCGAATCCCTGTGGCAAACGTATCTTGACGGAAGACATAGTACACCGGGAGGTGACCCCTGACCAGAAACTGCTGTCCCGGCGACTCATGACCAAGACCGACAGGATGCCCCGCTGGGCCGAGCGACTGTTTCCTGCCAATGTGGCTCACTCGGTGTACATACATATTGGAGGACTCTGTTGTGGACCCACAGAATCAGACCATGACCACCTTCACCTGGAACATCAACCACGCCCGGCCGATGGTGGTGGAGGAACGATGTGTTTACTGTGTGAACTCTGACAACAGTGGCTGGACCGAAATCCGCCGGGAAGCGTGGGTCTCCTCTAGCTTATGCGGTGTCTCCAGAGCTGTCTGGGAATTTGGTCTTGCCCAGTTCAAAAGCAACGTGACCAAGACTTTGAAGGGTTTTGAATATATCTTGGCGAAGCTGCAAGGCGAGGCTGCTTCCAAAACACTTATTAAGACAGCCAGGGAAGCCAAGGAGAAGGCAAAGGAGACGGCCCTGGCAGCTACAGAGAAGGCCAAGGACCTCGCCAGCAAGGCGGCCACCAa
>NM_013237.4
GCGCGGCCGGACAACTCATGGCGGCGGCGGCGGCGGCGGCAGCTGCTTGGGCGCGGTGCGGTGGTGACTGAGCTACGAGCCTGGCGGCGGGTGTGCGCCGAGCCCCGGCCCGGCCCGGCCCTCGCGTGCCTCCCAGGCTCCGCACCCCTGATGCTGCGCGGGTGCTGAGCCCGCTTCGGCCGGGACGATGGTGAAGTATTTCCTGGGCCAGAGCGTGCTCCGGAGTTCCTGGGACCAAGTGTTCGCCGCCTTCTGGCAGCGGTACCCGAATCCCTATAGCAAACATGTCTTGACGGAAGACATAGTACACCGGGAGGTGACCCCTGACCAGAAACTGCTGTCCCGGCGACTCCTGACCAAGACCAACAGGATGCCACGCTGGGCCGAGCGACTATTTCCTGCCAATGTTGCTCACTCGGTGTACGTCCTGGAGGACTCTATTGTGGACCCACAGAATCAGACCATGACTACCTTCACCTGGAACATCAACCACGCCCGGCTGATGGTGGTGGAGGAACGATGTGTTTACTGTGTGAACTCTGACAACAGTGGCTGGACTGAAATCCGCCGGGAAGCCTGGGTCTCCTCTAGCTTATTTGGTGTCTCCAGAGCTGTCCAGGAATTTGGTCTTGCCCGATTCAAAAGCAACGTGACCAAGACTATGAAGGGTTTTGAATATATCTTGGCTAAGCTGCAAGGCGAGGCCCCTTCCAAAACACTTGTTGAGACAGCCAAGGAAGCCAAGGAGAAGGCAAAGGAGACGGCACTGGCAGCTACAGAGAAGGCCAAGGACCTCGCCAGCAAGGCGGCCACCAagaagcagcagcagcagcaacagTTTGTGTAGCCAGTCTACCACCACCACAGCACCCCAGACAGCTAGGCTTAGCCTCTCTGCCCTCCCTTCATTGTACTTTATCATTAAAAATCAACTTCCAGCCCTGTCTGCTGTCTACGTGGTGGGTTGTGGGGATGCAGTTTGGCATCTGCAGTACACCAAGCACATGATTCATGTCTGAGCCaggtctgcttattctcccattgggcagctgaggaccgaggcacagaggtgcggtgacttgcccggggCTCCAGGTAGCCTGCAGGTTAACTGGCGGTAAGTGctagactgtaagcccgacaagggcagggcttttggttttgttctctgatgtgtctcagtatctagcacataatagacactcaataaatacttgttgaatTCA

Publications

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