Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name EIF4EBP2P2
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:42580814-42581639  UCSC
Coordinates (T2T) chr15:40387814-40388639  UCSC
Coordinates (hg19) chr15:42873012-42873837  UCSC
Strand -
Parental Sequence NM_004096.5
Parental seq. overlap 754 bp
Parental seq. overlap (%) 10.1%
Genomic Region Intragenic (STARD9)
Retrocopy Summary EIF4EBP2P2, located on chr15:42580814-42581639, is a retrocopy of the parental gene EIF4EBP2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EIF4EBP2
Full Name eukaryotic translation initiation factor 4E binding protein 2
Also known as 4EBP2|PHASII
Coordinate chr10:70404145-70428618
Strand +
Gene summary This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EIF4EBP2P2
Gorilla Gorilla gorilla EIF4EBP2P2
Orangutan Pongo abelii EIF4EBP2P2
Gibbon Nomascus leucogenys EIF4EBP2P2
Green monkey Chlorocebus sabaeus EIF4EBP2P3
Crab-eating macaque Macaca fascicularis EIF4EBP2P2
Rhesus Macaca mulatta EIF4EBP2P2
Baboon Papio anubis EIF4EBP2P2
Golden snub-nosed monkey Rhinopithecus roxellana EIF4EBP2P2
Marmoset Callithrix jacchus EIF4EBP2P1
Bonobo Pan paniscus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>EIF4EBP2P2
GGCGGCAGGGGCGGAGCCAGACGAGGGAACTAGAGGAAGCGAGCGAGGAGTGCGCAGAGCTCGCTTTTCCACCCGCCCTAGGAGCTGGAGCAGACCGGCCCGGCGCCGCCGCCTACCCGCCACACAAAGCCCAGAGCCCGCGTCCACAGCCATGTCCTCCTCCGCTGGCAGCGGCCACCAGCCCAGCCAGAGCCGCGCCTTCCCCACCCACACCGTGGCCATCAGCGACGCCGCGCAGCTACCTCTTGACTATTGCACCACGCCCGAGGGGACGCTCTTCTCCACCACACCAGGAGAAACTCAAATCATTTATGATAGAAAGTTTCTGTTGGATCTTCGCAGTTCTTCCATGGCTCAGACCCCACCTGCCATCTGCCCAATATCCCGGGAGTCACTAGCCCTGGCACCTTAACTGAAGACTCCACAAGTAGAAGTCAATAATTTGAACAACTTGAACAATCATGACAGGAAACATGCAGCTGGGGGGTGATGCTCAGTTGGAGATGGGCATCTGACTCTCCTGCAAGGATTAGAAGAAAAGCAGCAACACTGGTACCTGTGTGCACCTGATTTGGCCAATAGGATCAACAGTGAAAAGACAGAAGAGGCAATACCAGCAGTCCCCATTACAGTCTCCGTCTCCCACTCTTCCTCTGGGTGCCAAATGATGGGAAGATGAGCTTCATCTGACCATTTCTTCTCCCTGTCTCCTGTCCCCCTTCCCAGTTAAACAAGTTAGATTGAAGGCCCTTGGTGTATTTCTGTAGCGCTAAGCAGTCCTTAGAGGAAAACAGTTAAACTCTGGCTTTCCTAGt
>NM_004096.5
gcttccggtcgtcgtcgtcgccgctgctgccgctgctgttgctcctgaggctgctggctgaggccggaggatcgagcggcggcggcggcggcggctgagagggcggcggcgggagcggagcgggacgagggaacgggaggaagcgagcgaggagcgCGCAGAGCGCGCTTTTCCGTCCGCCTGAGGAgccgaagcagccccggccccgccgccgccgcctgcccgccgGACAAAGCCGAGAGCCCGCGCCCACAGCCATGTCCTCGTCAGCCGGCAGCGGCCACCAGCCCAGCCAGAGCCGCGCCATCCCCACCCGCACCGTGGCCATCAGCGACGCCGCGCAGCTACCTCATGACTATTGCACCACGCCCGGGGGGACGCTCTTCTCCACCACACCGGGAGGAACTCGAATCATTTATGACAGAAAGTTTCTGTTGGATCGTCGCAATTCTCCCATGGCTCAGACCCCACCCTGCCACCTGCCCAATATCCCAGGAGTCACTAGCCCTGGCACCTTAATTGAAGACTCCAAAGTAGAAGTAAACAATTTGAACAACTTGAACAATCACGACAGGAAACATGCAGTTGGGGATGATGCTCAGTTCGAGATGGACATCTGACTCTCCTGCAAGGATTAGAAGAAAAGCAGCAACACTGATACTTGTGTGCACCTGATTTGGCCAATAGGATCAACAGTGAAAAGACAGAAGAGGCAATACCAGCAGTCCCCATTACAGTCTCCACCTCCCCGTCTTCCTCTGGGTGCCAAATGATGGGAAGATGAGCTTCATCTGACCATTTCTTCTCCCTGTCTCCTGTTCCCCTTCCCAGTTAAACAGGTTAGATTGAAGGCCCTTGCTGTATTTCTGTAGAGCTAAGCAGCCCTTAGAGGAAAACAGTTCAACTCTGACTTTCCTAGTTGTTTTTTTATTGAGAGCCACCCTCATACCCTGTAATTTTGTCCCAAATCAAATATCAACCTACCAACAACTGCCTGGCTGGGAAGTCTGGGGAAGGGATACAGAGCTTGGTGGGCCTAACACCATTCATATTCCTTACCCTCTGTCTCTCCTCCCTGTATCCCACCTATGGTTCAGTGTTGCAAGAGTCTGGGCTTGGGGTCTTTAAAACCAGCAGGGGGAAATGATAAAAAGAGAGCTGCTTTCCCTTTTACCTTGAGGTATTCGTCCCTCGGGACAGAGCACAGCTTGTGCAACTCTGGTAGCGTTACCCTGTGACACTGTTTTGAGGTCCACTTCCTTTCTTTCCTCTGGGAGGAATGTCTTCTGTCTTTGGTATTATAGTTCATCTTCCCATTCTTTTACTTAGTGCATTTGTGCAGATATTTTTAACTCTGTACATCAGAAGAGAGCCCTTGGTAACCAGTTTTGCTCTTCTTCTGCCACTCCTCCCTGCTTGCATCTCGTTGCTGGCAGAGTCCTCTTGTACTTCAAGAAAGCAAAGTGATTTTGTCTGCTCCTAGAGCAGGTCCATACCAAGTAATAGAGGCACTTTAGCTTCCACTTGGTGGGTAAGGCCTGATCATAGTATTCTGTCAGATAATGCCTAAGAATGACCGCTGAAGAACGTTGACCCATTTGAGTACCCGGTCTCAGTCGTCATTTTTAAGTCCAGTGAGCATTGTGGTAGTTGTTCTTAGATTGCAGTTTCTTATGTTTTGAGTTTGAAGTTGATTTTCAGAATGTTCTTAGAAAAGAACTGCATTTTTTTCCTTTGTGGATCTGCTTTGTTTGGCTGCTGGGATAGATAAGCATGGGCTTAAAAAATGTGTTCCTCCCAGTTTTCTTGCCTTTCCTGTTGTACTCTGAATTtctctccctacctccctcactttcttcctctctccttcctttccttcctTTTTCTCTACCAGGCCATTTTTCAAATTTACATCAAAGATACCTGAAGTGTTGGTATCTGAGAATATCTGTCACTCCTCTTATCTGAGAAGTGACCTTTTATTTTTAAGATGACTACAGACCTATTTTTAGATATGTTTTCAGTACAATTTTGAACAGCAACTTTTTAATTAAACATCTTCCAGTGTTAGGAAGTTGAGAAACGTTCATAGGCAAGTCTGCTGTTCTATGTCACCATCTTTTGTCTCCCCTAGTCCCCCAGGAGCTCTTTCCTTTCCCCTCtagttttgggtgtgcatgtttggagtttgtagtgggtggtttgtaAAACTGGACCATTCTGCCTTGCTATGGGTTGTTCAAGAAAGCCTCATTCTTTTCTGTGACCCTTTCGCTTTTGCATTCACCCTCCTTCCCACCTACCTGTCCTGGGGCTGTTGAGCAGCATAATAATCCCGGGAGAATGATTCCCCTCATAGAAAGACAAAAGCATCCATCCCCTCATAGTTAAGTAGCCACTGGTGTCCTGGGAATTTCTGGTTGGATTTGGTGCCCTGAACTTTTTTATTAAGAAATCAGATCCCAGGGTGAGAGTAACAGGCCATTTGGCCAAGAAAGAAACCTGTTTGTTTTTCTTTTGAACTATGAAAAGACCCTGTTTGTGAATATATTTTAGAAAGAGAGGAAGGATGTCTGCAGAACTTTGTTCTGTTTTCTGCCACAAAAATGTGAATAGTTCAGAGTGAAAACCTTTTGTGATGGTTGATGTCTCAGGAATAAGCTGGATCTCCAATGTTTTGGGGATGCTTTGAGTCTCAAAAAAAATTGATAATCAGAAAAGTAATTTTTGTTTGTTTGTTTAATGTATCCCTGTTCTGTTTTTAATTAAACTCCAAGTCTCATTTTACATATTCTTGGAAAAACCTAAGTTGCTCTGTAATTTACATAAGAAGCATGCTCAGGACCTCTTTGTACCCCGGGGAGCCTGATTCTTTGGGAATGAAGCTTTTCATTCTTCATACACTGGCCTTGGCATCCTGTGGAATTTGACCCAACTAGCAGCTAGTCAGTCTGTCAGTGAGCAGAAGAGTGAACTCTTCTTGATCTTTATTGCTATGTGTGAAAACTTGGCTTCCTCACTGAACGGTGAGGAATGGATTTAAAGCATGAGCTTTAGTAGTATCAAGATGCCATTTTCCTTTTTCTTGCTGTCTTGGGGAGCTTCTGCATGTGACCCCCTAATCAGAAGGCATGTTTTTAGTATTTCTTGGGAGTGTCAGCTGTATAATGCAGCAGCTGTTCAATCCCTTACCCTTCTCTGCAAGGACTTCCTTACAGCTTGGTGCAGTTCTTTCCCAGAGGCCACCACTACTAGACAGTCTTTCTTTTATCTTATGGAGATAAATTGGCATTTAAAAAATAATTTCACAAGGCATGAGATAAACTTTCAATAGATGATACCTTTGTGTCATGCCTCATGGAATTATTTTTAGAACAAGCCAGAGTCCATTGAGTGGTTTACCTCTGCATGTTTGGAGGGAACCTCACAGATGAAACCCTTAATGAATAATGTGTCCGGGGTTTTTTAGAGAGAAGGAGCACTCTTAAGTTACCACTTTGAGACAGCTCTTAACATCTTAGTGACCATTTGTAGTTTTCTTTTTATGAGGAACCCATGCTTCTATACTTGGGCGGACAATCGAGCTTAATGAGAAGTGACTTCCCTTCAAATTCCAACAGCAGACATGCATTGTCATGATTCTGTCTTCTTTTTAGTGTGGTTTATTGAGTTCAGCAGTTCTCATATTCTGTTTAAATAGGTACAGCATTTTCAAGGGCACAGATACAGAGAAGCTGGCTTTCTAGGTATTGGGCTTCCAAGCCAAGAGTTTTGTCCTTCCACCtgtattagttatctattgctgtgtaaaaaattaccctaaatttagtatgttaaaatagtaaacattatctgtcagtttctgtgggttaagaatttgggagtagtttaacatgatggttctggcccatggtatcatgaagttacagtcaagattgaacaggggctgcagtcagctggagctggagaaaccacttccaagttctctctttgtggccgttggcaggatgcctcagtttcttcccatgtgggtctctgcgtagggcagcatgagtgtcctcacaccatgacacctggcttctccctgagcagctgattccagagatcatggggcagggccaggagaaagctgcagtgccttttaagacatagtcttggaaaggacacaccgtcacttcttatcctagttgttagaagcaagccactaagttcagcctgcactcaaggagagaggaattacacatacctctaccccaatggagcagtagcaaagaatttatggacatatcttaaaagcaccacaCCCCAACTGGGGATGAAAGTAGGTCAACAGGGAGGTAGGTTTAATCTAGATAAGCTGAAAGATAGATTGCTATCAAAAACAGTTCTCCAAGATGTGCATAGCCAAACTGGGATAGAAGGCAAACTCCCCAAAGCTACCTGCTGGTTTTGAGAGGGGTGGTAAGACATGGCAATTCCCAGGAGTAGTAGAAAATAATATGCCTGACTACCAACAGCTCAAGTATGCTTATTTGCACATCCTAGACTTGGTGTCTGTAAGACTCAGTTACCACTTTTATTTTCCTGTAGCTAGGAGTTAGCAAAAGGAACTGGGGCCTTCCAGCCGAGCCACTAAACCTGTCTTATTTGGAATGGGGATTGTCCAGCAAAGGGAGCAAACATGAATTAGATGTTAAGCTATTGAGCTGAAGAAAAGAAAGCAGTTCACATTTAGGTGAAATAGATGATGTTATCAGGAAGCCAGGTTCCCACCAGAGTCGGTGCTTGGTACCTGGTCTCTCCAGTCTCAACAGACTCAGGTCAGGTCTCTCACCCAGGAAGCAACCACTCAATAAAATAGAGAACATCTGAGAATTACAAATGTCTATGCTTGATTGCTCCTCTAAATCCAGTGCATAGGTTAACCCTGCATGCCCATTTCTTCCTGGGCTTCTTGATGGCAATGTGTTCTTAAATAACTGGTCTTGTGTTCATGCTAAAGACAAACTTACATGAAGTTTTTCAGTTTAAGACATTCTAGTGAATGGCTGCTATGTGTTTCTGGCACTCATTCCTAACCAAGTCTTTAGAGATTTCAGATGACCTTAAAGATGCAATATCTttttctttctttctttctttctttttttctgagacaagagttgcgccctgtcgcccaggctggggtgctggagtgcagtggtgcgatctcagctcactgcagcctctgcttcccaggttcaagtgtttctcctgcctcagccttccgagtagctgggattacaggcatgtaccactatgcctggctaatttttatttctatatttttagtagagatggggtttcatcatgtttgccaggctggtctcgaactcctggcctcaagtgatccgcccacctcagcctcccaaagtgctgggattacaggcgcgagccaccgcgcctggccAAAGATGCAAATTCTTGTTTGGATTTATGCTCTGCCTCTTCCCAGCATTTTCTTATCTGTAGCCCTGCTTGCTTGAGAGTATACTTGGATAAGAAGTATTGCTGTTGAGGGAGCTATAAGAAAAGGATTCTTCTTCCAGAAGTAAAGAACTCATCTTTAGAGTACCTTTAAATGAATTTTGTTTTTCTTTCTTATTTTGAGGTGGATTGGTCTTCTCTTTTTTTGGGTTTCCAGCTCACTGGGACTCTCAGACCTTACCTTTCCAGCTCAAACACCATTAGTTAAATTCCTTCATTCTCATTAGAATGCAGCCTGCTGAGTATGTGGGTTTCACTGCCGGAGTCCATCATTTAGCCAGTATACATAGAGGAACTGCTTCGAATCAAGGCAACTGGTGAAGGGCTTAGCATGTTGGCAGCAATATCCCAGAGATTGAATCTGTTTGCATTTTCCTCATCTAGGATAACAGCTGCTTGAAGCCAGGGCTCTTAGCCCTTTGCATTCCCCTTGAGCGAGGAAGCCACACTGCCTTTCTGTGTCTGGTTCAGAGCTCTTCCTTCTTGGCATGTTTTCTGGACTACATGCACATGGGCAGCTATAGATTAATCTGCAAAACCTAGTCACTTACCTACCCATAATATCTGGGAAGGTGTGGTATTTGTTTTAAAGAAACATTGTTTCTTTGGGAGGGCAGTTTCTGTCTGGACTTTGAGGTGGACTTAGTTATCCCTACAGTTCTTTAACTCTCAGCTTTTAATAAAAGATGAAATCAGATATTGATGCAGTTGGGTCACAATTCTTTAGAATGCTTCTACCCCAGGGCCGCTTCCTGTTCCTAGTCATGGTTTTCCAGTTTAGTAGTGGAGTTTCTTGAGGCTAACTTACAGAAATTTCTAACTGAAAACTTTAAGAGTTATTGATACTTGTTTTTTCAGTCAGTCACTTACATCACCTAGCCTACTCTCTGGAATTTAAATTTATTTCTCTAGGCTGGTCCTGGAAGTTGATAACCTTTTGGCAAAGCTTAGATTTAGGAGAAGGCTTGAGTCCCTGTTCAGCGGGTCTGTGGATTCTCTTTGCTTATGGCTCTCTGCCTGCAGCCCTGGCAGACCATACTGTATGTCATGGATACCCAGTGGAAATATTACTGAGATGAAACACATTTCCAAGGGTATTTAAACTCTCACTCTGCCACCTTTCTAAGGGTGGGAGGCTGGCAGAGATGCTGCAATGCTTGATAATCATTTGGCCACACTGAAATTTCCAAAGGGAGCTCTTGCCGGTGCTTAAAACCAAAACTCCTGGACACTTAGAAAATTCCATGAATCTAGCACAAAATATCCATTCTTGCCCAAGTGTATCCCCTTTCTCTCCAGCTTAATCttttttttttttttttttttAAAGCCCAGGCCAAGGGTACTTTTAACTGGAAACTGGGGAGGAGGGAAGAACACTAGCAGGGAGCTAAGAGGCAGGTTGCTGGGTAAGCCATCCTGCTCCTACCTGGTGCCTGTATCTACATTGCTGAGTGCTGTGCGCCAGTGCCTTTCCTTCATCTGCAGATGGAGCCCATCTCTTTCCACCTGGGTGAGGAGACCCTCTGCTACTCCAGGGGTAAACCTTAAAGAAGGTGTCTTGAAGAGCCCAGAGGACACTCACGTGCTAAGGTGTCCATTTTATGCATCTTTAAAATATTTTATTTAAAAAAAAAAATAGCCCTGCCCTGTCTTAGTGCCACTAACGGCCCAGTTCCATCCATTCTGAATGGAAAAGCGGAGACTGCCAGCACTTTCCTTGGTCTTCCCTTTGTCTCCCATGATGTGTTGTTCCCTCATCCCTCCCATCCATTTCACTGTGTGTGGATGGATAGCAGAGGGTACCACGCAGTCCTTGAGGCAGTCCTGTGTGATTCCATGATCAGTTGTTTTTGTATTTTAACTATTCTTCCAAACCAGCAGATGTTTGGAAATTAAGGAAAAAATTAAATTCTCATCAATGGTTGCTGTTATAGTTAAATCAGTAAAGATCTTGAGTATCAA

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