Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name HNRNPMP1
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:44448126-44449351  UCSC
Coordinates (T2T) chr15:42255805-42257030  UCSC
Coordinates (hg19) chr15:44740324-44741549  UCSC
Strand -
Parental Sequence NM_005968.5
Parental seq. overlap 1044 bp
Parental seq. overlap (%) 42%
Genomic Region Intragenic (CTDSPL2)
Retrocopy Summary HNRNPMP1, located on chr15:44448126-44449351, is a retrocopy of the parental gene HNRNPM. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HNRNPM
Full Name heterogeneous nuclear ribonucleoprotein M
Also known as CEAR|HNRNPM4|HNRPM|HNRPM4|HTGR1|NAGR1|hnRNP M
Coordinate chr19:8444575-8489114
Strand +
Gene summary This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HNRNPMP1
Bonobo Pan paniscus HNRNPMP1
Gorilla Gorilla gorilla HNRNPMP1
Orangutan Pongo abelii HNRNPMP1
Gibbon Nomascus leucogenys HNRNPMP1
Green monkey Chlorocebus sabaeus HNRNPMP2
Crab-eating macaque Macaca fascicularis HNRNPMP1
Rhesus Macaca mulatta HNRNPMP1
Baboon Papio anubis HNRNPMP1
Golden snub-nosed monkey Rhinopithecus roxellana HNRNPMP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HNRNPMP1
CTGAAGGAAAGTCAGGGGATGTGCTGTTATTGAATTCAAGATGGAAGAAAACATAAAAAAAGCTATTCAGGTGCTAGACAAGCATAGTCTGAGTGGAAGACCACTGAAAGTGAAAGATCCTGATAGTGAACATGCCAGGAGAGCAATGCAAAACGTGATGGCTACCACTGGTGGAACAGATATGAGACCAAGTGGCCCAGAAATGATTACTATCCCACCTAGTATCTTAAATAATCCTAACATCCCAAATGAAATTATCCATGTATTACAGACAGAAAGACTTGGAAGCACAATATTTGTAGCAAATCAGGATTACAAAGTTGGCTGGAAGAAACTCAAGGAAATATTTTAGTATGGCTGATGTGGTGTTCTGAGCACATTCTTGAGGATAAAGATGAAAAAAATCATGGATTGGGCACTGTTACTTTTGAACAGTCCACTGAAGCTGTGCAAGCTATATCTACATTCAATGGCCAACTGCTGTGTGATAGACCAACGCAGGTAAAGACGGATGAGACCGCCTTACCAAAGGATTTTTTTTTCCCTCCTAAGCGTCCGCAGCTTCCCTATGGCCTTGGTGGTATTGGAACAGGGTTAGGACCAGGAGGGCAGACTATCGATGCCAATCACCTGAATAAAGGCACTGGAATGGGAAACAGGGCCTGCAGAAATTAGAATGGAGGGCATGGATTTAGAATAAAATGGGAGAAATGGAGGAGGGACCCCCATGGTGGCGGTATGGAAAATGTGGGTCAATTTGGCTCTGGGATGAACATGGGCAGAATAAAGGAAATCTTAGTAATACACTTAGGATAGGGAAGATCACTACAAAGCAGAGAGGAAGTGAAGGTGGAGGCAGCATCCCCAAAATCGAGAGGATGAGGCCCAAGCGCTGACTACACTGGGGGTGCCAGCATGGAATGCATGAGTCCAGGCCTGGGCCATGGTGTGGATCGTGTGGGTTCCAAGATGCAGCACATGGGTCTGGTCATGGACCGCATGGGCTTTGTGGAGCACAAAGGCTCCCACAGGGAGCGCATGGGCCTGCTGGGCCTTGACCAAATGGCCTCTAGCATCCAGCACACAGGCAAGGTCACGGAGCGCAGTGGCTCCGGCCTGGAGCACATGGGTGCCGGCATGGGCTTCAGCCTCAAGTGCACAGCTGCTCCCATTGACCATGTGGACCAAACCATTGAGCACATGGGCTCTGGTGTGGAGTGCATGGT
>NM_005968.5
ACACAAAGCCCAGACGCGGAGAAAATggcggcaggggtcgaagcggcggcggaggtggcggcgacggAGATCAAAATGGAGGAAGAGAGCGGCGCGCCCGGCGTGCCGAGCGGCAACGGGGCTCCGGGCCCTAAGGGTGAAGGAGAACGACCTGCTCAGAATGAGAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATCGCTTTGAGCCATATGCCAATCCAACTAAAAGATACAGAGCCTTCATTACAAACATACCTTTTGATGTGAAATGGCAGTCACTTAAAGACCTGGTTAAAGAAAAAGTTGGTGAGGTAACATACGTGGAGCTCTTAATGGACGCTGAAGGAAAGTCAAGGGGATGTGCTGTTGTTGAATTCAAGATGGAAGAGAGCATGAAAAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAAGACCACTGAAAGTCAAAGAAGATCCTGATGGTGAACATGCCAGGAGAGCAATGCAAAAGGTGATGGCTACGACTGGTGGGATGGGTATGGGACCAGGTGGCCCAGGAATGATTACTATCCCACCCAGTATCCTAAATAATCCCAACATCCCAAATGAGATTATCCATGCATTACAGGCTGGAAGACTTGGAAGCACAGTATTTGTAGCAAATCTGGATTATAAAGTTGGCTGGAAGAAACTGAAGGAAGTATTTAGTATGGCTGGTGTGGTGGTCCGAGCAGACATTCTTGAAGATAAAGATGGAAAAAGTCGTGGAATAGGCACTGTTACTTTTGAACAGTCCATTGAAGCTGTGCAAGCTATATCTATGTTCAATGGCCAGCTGCTATTTGATAGACCAATGCACGTCAAGATGGATGAGAGGGCCTTACCAAAAGGAGATTTCTTCCCTCCTGAGCGTCCACAACAACTTCCCCATGGCCTTGGTGGTATTGGCATGGGGTTAGGACCAGGAGGGCAACCCATTGATGCCAATCACCTGAATAAAGGCATCGGAATGGGAAACATAGGTCCCGCAGGAATGGGAATGGAAGGCATAGGATTTGGAATAAATAAAATGGGAGGAATGGAGGGGCCCTTTGGTGGTGGTATGGAAAACATGGGTCGATTTGGATCTGGGATGAACATGGGCAGGATAAATGAAATCCTAAGTAATGCACTGAAGAGAGGAGAGATCATTGCAAAGCAGGGAGGAGGTGGAGGTGGAGGAAGCGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGGTGCCGGCATGGAGCGCATGGGCGCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCGCATGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTCCAGCATTGAGCGCATGGGCCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATGGGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCGTGTGGGCCAGACCATTGAGCGCATGGGCTCTGGCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGTGCCCGCAGGTATGGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCCAACAATCTGGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCATGGGTGCCAACAGCCTCGAGCGCATGGGCCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCATGGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCATCGAGATGGAGCGTGGCAACTTCGGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTGCCAGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGGCCACGTGCTGTACGCCGACATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAGTCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAATGGCATGAAGCTGAGTGGCCGAGAGATTGACGTTCGAATTGATAGAAACGCTTAAGCAGTTGCCTTTTTTAAACATCGATACGAGACCTCTGAATTTGTATTTTTTCTTGTTAACCATTTTAATTTGTTGGCTGGATGTATAAAGATGTTTAAAAAATTCAGTTGCTTTTTGGGGTAATTTGAATTACTTTTTTAATGACTGGGGTTCCATTTGACTGTTTGCATTGAGATTGCAATGTGCGCAATTTTTTTTGTAGTTGTGGCATCTTGTTGACATCGAATATGACTTTGATAATAAATACCGGTTCCTGAAAA

Publications

PMID - Link Title