Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DCAF13P3
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:50944629-50946566  UCSC
Coordinates (T2T) chr15:48752261-48754198  UCSC
Coordinates (hg19) chr15:51236826-51238763  UCSC
Strand +
Parental Sequence NM_015420.7
Parental seq. overlap 1800 bp
Parental seq. overlap (%) 90.6%
Genomic Region Intragenic (AP4E1)
Retrocopy Summary DCAF13P3, located on chr15:50944629-50946566, is a retrocopy of the parental gene DCAF13. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DCAF13
Full Name DDB1 and CUL4 associated factor 13
Also known as GM83|HSPC064|Sof1|WDSOF1
Coordinate chr8:103415386-103443453
Strand +
Gene summary Enables estrogen receptor binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in several cellular components, including centrosome; cytosol; and nuclear lumen. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DCAF13P1
Bonobo Pan paniscus DCAF13P1
Gorilla Gorilla gorilla DCAF13P2
Orangutan Pongo abelii DCAF13P2
Gibbon Nomascus leucogenys DCAF13P1
Green monkey Chlorocebus sabaeus DCAF13P2
Crab-eating macaque Macaca fascicularis DCAF13P2
Rhesus Macaca mulatta DCAF13P2
Golden snub-nosed monkey Rhinopithecus roxellana DCAF13P1
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DCAF13P3
GCTCGTGGAGTCCGGCCAGAAGAGCAACCAAGATGAGGATGAAGATACTGAGCCAGAATCTGGACAATTATGTCTGTGAAACCAAGTTGGACTTACAGAGAGTTCCAAGAAACTATGATCCTACCTTACATCCTTTTGAGGTCCCATGAGAATATGTAAGAGCTTTAAATGCTACCAAAATGGAATGAGTATTTGCAAAACCATTCCTTGCTTTGCTGGATGGTCACCAAGATGGAGTCAGTTGCTTGGCAAAGCATCCAAAGAACCTGGCTACTGTCCTTTCTGGGGCGTGTGATGGAGAGGTTAGAATTTGGAACCTGACTCAACAGAAATGTATCCATACAATACAAGCACATGAAGGCTTTGTATAAGGAATACGTACTCACTTTTGTGGGACTTCTTTTTTCACCGTTGGTGGTGACAAAACTGTGAAACAATGGAAAATGGATGGGCCAGGCTATGGAGATGAGGAAGAACCATTACATACAACATTAGGAAAGACAGTGTATACTGGGGTTTATCATCACTGTAAAGAAGCTGTTTTTGCCACATGTGGACAGCAAGTAGACATTTGGGATGAACAAAGAACTAATCCTGTATGTTCAATGACCTGGGGATTTGACAGTGTAAGTAGTGTTAAATTTAACCCAATCGAGACATTTCTCTTGGGAAGTTTGTGCGTCTGACAGGAATATAGTACTGTACAACATGAGGCAAGCTACTCCTTTGAAAAAGGTTATATTAGATATGAGAACAAATACAGTTTGTTGGAACCCTATGGAAGCTTTCATTTTTACGGCAGCAAATGAAGACTATAACTTACATACTTTTGATATGTGTGCACTGGACACTCCTGTAATGTTCCATATGGATCATGTATCTGCAGTGCTTGACATGGATTACCCTCCCACTGGGAAAGAGCTTGTGTCTGCTAGTTTCGATAAAGCTATTTGTATCTTTCCTATAGACAAAAGTTGAAGCAGGGAGGTATATCACACAAAGCGAATGCAACATGTTATCTGTGTAAAATGCACTTCTGACAGCAAGTATATTATGTGTGGATCTGATGAAATGAACATTTGCCTGTGGAAAGCTAATGCTTCTGAAAAATTTGGTGTGCTTACATCATGAGAAAAAGCAGCTAAGGATTATAACTAGAAATTGAAGGAGAAATTTCAGCATCATCCTGATATAAAATGTATAGCTTGTCATTGACATCTACCAAAATCTATCTACAGCCAGATTCAGGAACAGTGCATCATGAAAGAAGCTCGTCGAAGAAAGGAAGTGAATCGTATTAAACACAGCAAGCCTGGATCTGTGCCAATTGTGTCAGAGAAGAAGAAACATGTAGGGGCAGTTGTAAAATAATTAGTATTCCTAACAATCCTGATGTACAATTATTTGTTACTTTTGATTTGAGAACTCTACAAATTAAAGTGCTGGGACTAGATTAATTGCATACATTTTAGTTACATGTGTAGAGCTTTATTGTTGCTCCTTTTAGCTACCCTGAAAAATGCCTAGTTGATAAAGACTATCTAACTATTTTATCCTTAATCTGCATTCTTTTATTGAAGAATACAGTATTTGCAACTAACTCATTTTTTCCTGTTTTAATTACAGATATACTCTGTATATTCTCTCTGATCTATTATTGTAGACACTGCACATTCAAATTGACATTTAAGACCAAACGTCTCTTATGTTATCTTTAACATTACTTTGAATAATAATTACAATGATGTTTCTTCCTATGATTCCACATAACATTTAGAAGAATGTCAACTTTTTATAACTGAATGTATTTCTAGTGCTTTACTTATATTTGGCTTTTCGACTCTTACAAAACCATCAGTCTGCATTTATATAACTTTTATAAATAATATTATAATTTGGGTCAAGTTAAGATAATAAAACTTCCTTTCAGCGTTGAAA
>NM_015420.7
GTGGCGGTGGGCGGAACTCCTAGCGGACACCTCGTGGAGTCCGGCCGGAAGAGCAACCGAGATGAAGGTGAAGATGCTGAGCCGGAATCCGGACAATTATGTCCGCGAAACCAAGTTGGACTTACAGAGAGTTCCAAGAAACTATGATCCTGCTTTACATCCTTTTGAGGTCCCACGAGAATATATAAGAGCTTTAAATGCTACCAAACTGGAACGAGTATTTGCAAAACCATTCCTTGCTTCGCTGGATGGTCACCGTGATGGAGTCAATTGCTTGGCAAAGCATCCAGAGAAGCTGGCTACTGTCCTTTCTGGGGCGTGTGATGGAGAGGTTAGAATTTGGAATCTAACTCAGCGGAATTGTATCCGTACAATACAAGCACATGAAGGCTTTGTACGAGGAATATGTACTCGCTTTTGTGGGACTTCTTTTTTCACTGTTGGTGATGACAAAACTGTGAAGCAGTGGAAAATGGATGGGCCAGGCTATGGAGACGAGGAAGAGCCATTACATACAATATTAGGAAAGACAGTGTATACTGGGATTGATCATCACTGGAAAGAAGCTGTTTTTGCCACATGTGGACAGCAAGTAGACATTTGGGATGAACAAAGAACTAATCCTATATGTTCAATGACCTGGGGATTTGACAGTATAAGTAGTGTTAAATTTAACCCAATTGAGACATTTCTCTTGGGAAGTTGTGCATCTGACAGGAATATAGTACTGTACGATATGAGGCAAGCTACTCCTTTGAAAAAGGTTATCTTAGATATGAGAACAAATACAATCTGTTGGAACCCTATGGAAGCTTTCATTTTTACAGCAGCAAATGAAGATTATAACTTATATACTTTTGATATGCGTGCACTGGACACTCCTGTAATGGTCCATATGGATCATGTATCTGCAGTGCTTGATGTGGATTACTCTCCCACTGGGAAGGAGTTTGTGTCTGCTAGTTTCGATAAATCTATTCGAATCTTTCCTGTAGACAAAAGTCGAAGCAGGGAGGTATATCATACAAAGAGAATGCAACATGTTATCTGTGTAAAATGGACTTCTGACAGCAAGTATATTATGTGTGGATCTGATGAAATGAACATTCGCCTGTGGAAAGCTAATGCTTCTGAAAAATTGGGTGTGCTTACATCACGAGAAAAAGCAGCCAAGGATTATAACCAGAAATTGAAGGAGAAATTTCAGCATTATCCTCATATAAAACGTATAGCTCGTCATCGACATCTACCAAAATCTATCTATAGCCAGATTCAGGAACAGCGCATCATGAAAGAAGCTCGTCGACGAAAGGAAGTGAATCGTATTAAACACAGCAAGCCTGGATCTGTGCCACTTGTGTCAGAGAAGAAGAAACACGTAGTGGCAGTTGTAAAATAATTGGTATTCCTAACAATCCTGATGTATAATTATTTGTTACTTTTGATTTGAGAACTCTACAAATAAAAGTGCTGGGACTAGATTAATTGCAAACATTTTAGTTATATGTGTAGAGCTTTATTGTTACTCCTTTTAGCTACCCTGAAAAATGATCCTTAAAGGTGGCCTAGTTGGTAAGACTGTTTTATCCTTAATCTGCATTCTTCTTTCATTGTAGAATACAGTATTTGCAACTCATTTTTTCTTGTTTTTATTACAGATATACTTACTTTCTCTTTGATCTATTATTGTAGACACTATACATTCAAATTGACATTTAAGACCAAACATCTCTTATGTTATCTTTAATATTACTTTGAATAATGATTGCAATGATGTTTCTTCCTGTGATTCCACATAACATTTAGAATAATGATGTCAATTTTTTACAACTGAATTTATTTCTAGTGCTTTACTTATATTTGGCTTTTTGACTCTTTTAAAACAATCAGCCTGCATTTATATAACTTTTATAAATAATAATATAATTTGGGTCAAGTTAAGATATTAAAAGTTCCTTTCAGCATTGAAA

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