Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PIGHP1
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:59676689-59677854  UCSC
Coordinates (T2T) chr15:57478406-57479571  UCSC
Coordinates (hg19) chr15:59968888-59970053  UCSC
Strand +
Parental Sequence NM_004569.5
Parental seq. overlap 1098 bp
Parental seq. overlap (%) 78.5%
Genomic Region Intragenic (BNIP2)
Retrocopy Summary PIGHP1, located on chr15:59676689-59677854, is a retrocopy of the parental gene PIGH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PIGH
Full Name phosphatidylinositol glycan anchor biosynthesis class H
Also known as GPI-H
Coordinate chr14:67589306-67600302
Strand -
Gene summary This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PIGHP1
Bonobo Pan paniscus PIGHP1
Gorilla Gorilla gorilla PIGHP1
Orangutan Pongo abelii PIGHP1
Gibbon Nomascus leucogenys PIGHP1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PIGHP1
AACGGCTAGGGCAGGCGAGCgCAGAGTTGGGGTGTCATGGAGGATGAGCGGAGCTTTTCGGATATCTGCGGTGGCCGCCTGGCCCTGCAGCGCCGCTACTACTTCCCTTCCTGCCGGGAATTCTGCCTCAGCTGCCCTGGGCTCTCGCTGCGTTCGCTCACCGCTGTCACCTGCACGGTGTGGCTGGCAGCCTACGGACTCTTCACCCTCTGCGAGAACAGCATGATCCTCTCTGCTGCCATCTTCATCACCCTCTTAGGTCTGCTTGGTTATCTCCATTTTGTGAAGATTGATCAGGAGACTGTTAATCATTGATTCCCTTGGCATTCAGATGACTTCATCTTATGCTTCAGGCTAAGAAAGCACTACCTTCATAGAAATGGGCAAGGTCAAGGATATTGTCATCAATGAGGCTATTTACATGCAGAAGGTGATTTACTACCTCTGCATCTTATTGAAGGATCCAGTGGAACCACATGGGATATCCCAAGTAGTACCCGTCTTCCAGAGTGCCAAGCCCCGGCTGGACTGCTTGACTGAAGTATACAGGAGCTGCCAGGGGATCCTGGCACACCAGAAAGCCACATCAACAAGCCCATGAGCCCCAGCGTTCAGAAGGCCAGCATCGTCTTCCATGGGAGATGACTCTTAAGCCATAAGGGTTGGTTTTCCGTACTCCAAACCATCAGGTGGACACAGTCCTAGGAACCATTATGGATATAGTGCATCTCAGAGCCATAGAGCAGGTGACTGGAAATCTAACTCAGTATATTTCCACGTATTATAGTGTTTTCCTTGTAAGGTTTTGCCTACTTTACCAAAGGAGGGGAGACCTTAAGAATTTTGACACAGTATGTCAAAAGTAATGTCAGCAAAGAACATTGGGAAATTGCTAAGCATGTTCAGGTTTACTTTGTTGATGTTTGTGAAGCAAAACAATGGGAAACTGACATCAGATGTCTTGAGAAAGCTATATTTTCCATTAGTGCCCCTTGTGTAAAGTTACAAAAAAAACAAGCCCTCCAGGAACTGGTTAGCAGGAAGAAATGTCCTACAAAAGACGAGTCTCTCAACCTAGCGCCTGTGTTCTGTACAGGGCTTATTTACTCTTAATAAACAGATATCCTTCCAAAA
>NM_004569.5
GAGACGGCCAGGGCCGGCGAGCGCAGTGCAGCGCCGCGCGGTGCGGGCGGCCGAGTGGGGGCGTCATGGAGGATGAGCGGAGCTTTTCGGATATCTGCGGCGGCCGCCTGGCGCTGCAGCGCCGCTACTACTCCCCGTCCTGCCGGGAATTCTGCCTCAGCTGCCCTCGGCTCTCGCTGCGTTCGCTCACCGCTGTCACCTGCACGGTGTGGCTGGCGGCCTACGGACTCTTCACCCTCTGCGAGAACAGCATGATCCTCTCTGCTGCCATCTTCATCACCCTCTTAGGTCTGCTTGGTTATCTCCATTTTGTGAAGATTGATCAGGAGACTCTGTTAATCATTGATTCCCTTGGCATTCAGATGACTTCATCTTATGCTTCAGGCAAAGAAAGCACTACCTTCATAGAAATGGGCAAGGTCAAGGATATTGTCATCAATGAGGCCATTTACATGCAGAAGGTGATTTACTACCTCTGCATCTTATTGAAAGATCCAGTGGAACCACATGGGATATCCCAAGTAGTACCCGTCTTCCAGAGTGCCAAGCCCCGGCTGGACTGCTTGATTGAAGTATACAGGAGCTGCCAGGAGATCCTGGCACACCAGAAAGCCACATCAACAAGCCCATGAGCCCCAGCGTTCAGAAGGCCAGCATTGTCTTCCATGGGAGATGACTCTTAAGCCATAGGGGCTGGTTTTCCGTACTCCAAACCATCAGGTGGACACAGTCCTAGGAACCATTATGGATGTAGTGCATCTTAGAGCCATAGAGCAGGTGACTGGAAATCTAACTCAGTATATTTCCGTGTATTATAGTGTTTTCCTTGTAAGGTTTTGCCTACTTTACCAAAGGAGGGGAGACCTTAAGAATTTTGACACAGTATGTCAAAAGTAATGTCAGCAAAGAACACTTTCGGAAATTGCTAAGCATGTTCAGGTTTACTTTGTTGATGTTTGTGAAGCAAAACAATGGGAAACTGACATCAGATGTCTTGAGAAAGCTATATTTTCCAATAGTACCCCTTGTGTAAAGTTACGAAAAAAACAAGCCCTTCAGTACTGGTTAGCAGGAAGAAATGTCCTACAAAAGACGAGTCTGTCAACCTAGTGCCTGTGTTCTGTACAGGGCTTATTTATTTACTGTTAATAAACAGATCTTCCAAAACACACAGTTACCTGGTTCACAGATAGCTGCTTTTTATTGACAAACAAGATCATAGTATTTCAGTCATGGTGTCAAGCACATTAATACTTTTCTGTTACTCAGCATTTTTTTTTATATCAGTTCAAAAGCTACTTTTGCCAAGAAGGATGAGACAAAAGGCCAGACAGAAATTGGACTTTGGTTTTCAGACATGGGACTCTCATGTTAACAAAGAATAAATAAGCAAA

Publications

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