Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CIAPIN1P1
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:68833770-68835360  UCSC
Coordinates (T2T) chr15:66656312-66657901  UCSC
Coordinates (hg19) chr15:69126109-69127699  UCSC
Strand +
Parental Sequence NM_001308347.2
Parental seq. overlap 1398 bp
Parental seq. overlap (%) 69%
Genomic Region Intergenic
Retrocopy Summary CIAPIN1P1, located on chr15:68833770-68835360, is a retrocopy of the parental gene CIAPIN1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CIAPIN1
Full Name cytokine induced apoptosis inhibitor 1
Also known as Anamorsin|CIAE2|DRE2|PRO0915
Coordinate chr16:57428187-57447385
Strand -
Gene summary CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CIAPIN1P1
Bonobo Pan paniscus CIAPIN1P1
Gorilla Gorilla gorilla CIAPIN1P1
Orangutan Pongo abelii CIAPIN1P1
Gibbon Nomascus leucogenys CIAPIN1P2
Green monkey Chlorocebus sabaeus CIAPIN1P2
Crab-eating macaque Macaca fascicularis CIAPIN1P2
Rhesus Macaca mulatta CIAPIN1P2
Baboon Papio anubis CIAPIN1P2
Golden snub-nosed monkey Rhinopithecus roxellana CIAPIN1P1
Marmoset Callithrix jacchus CIAPIN1P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CIAPIN1P1
GGCAGTTTTTAGGTCCATCAGCACTGCACTGCAGGAATGGCAGATTTTGGGATCTCTGCTGGCCAGTTTGTGGCAGTGGTCTGGGATAAGTCATCCCCAGTGCAGGCTCTGAAAGATCTGGTGGATAAGCTTCAAGTGTTAACTGGCAATGAGGGCCGCGTGTCTGTGGAAAACAACCAGCTGTTGCAGTCTGCCCACAAATAATCCAGCTTTGACATTATTTTGTTGGGTTTAGTCCTGGGAAGCACCACTCTACTGAGTGCTGAGATTTTGGCTGAAATTGCCCGGATCCTTCGGCCTAGTGGATGTCTTTTTCTGAAAGAACCAGTAGATCCAGCTGTAGATAACAACAGCAAAGCGAAGACAGCAAGCTGTGTTCAGCCCTGACTGCTTCCGGTCTTGTGGAAGTGAAAGAGCTGCCATGGGAGCCCTTAAGCCCTGAGGAGGTACAGTCTGTTCAAGAACACCTGGGTCATGAAAGTGACAGCCTGCTCTTTGTTCAGATCACAAGCaCTTTGAAGTGAGTTCTTCTAGTCAGCTTAAGCTTTCCATCACCAAGAAGTCATCTCCTTCAGTGAAGCCTGCTGGGTACCCTGCTGCTGCCAAGCTGTGGACCCTCTCAGCCAATGATATGGAGGATGACAGCATGGATCTCATTGACTCAGAGGAGCTGCTGGATCCAGAAGATTTGAAGAAGCCAGATCCGACTTCCCTGCAGGCTGCTCCTTGTGGGGAAGGGAAAAAGAGGAAGACCTGCCAGAGCTGCACCCGTGGCCTTGCCGAAGAACTGGAAAAAGAGAAGTCAAGGGAGCAGATGAGCTCCCAACCCAAGTCAGCTTGTGGAAACTGCTATCTGGGCAATAGTTTCCACTGTGCCAGCTGCCCCTACCTTGGGATACCAGCCTTCAAACCTGGGGAAAAGGTGCTTCTGAGCAATAGCAGTCTTTACCATGCCTAGGAGGGACCCGACATGGGACACATCTGCTCCTTTGGCCAACTCCTGTTCCTCAAATCCCACCACGGTGCTCCTCCCACCTCCTCTGGATTTCTTCTCTCTGAGATCCATTTGCAAAGTGGGTGCTTAGCAGACAGATTGAAGCTGGCTGGGGGGGGCACAGTGGTGTGTAGTGTATATCAAAAGACCAAGGTATTATGGGGCCCCATTACCCAGAATGGGATGGGTTTCTTCACCTCATGTTAAGAGAAGGGAGTATGTCCTGAAGAAGCCCTTCTCCTCATGTTAAAATGCTGACCAAAACACTCTTGAGCCCAGGCATCCTTGAGCATCAACACTCTGTGACAAAGCTCCAGGCCCTGGCCCCTAGTCTAATCTCAGCAATGCTGCCAGCTACTTGTCTTTCAGAGTTGTTAGTTTACTCCATACTTCGTGACACGGTCAAGTGTCTCATGACCTCAGGGTACCAGAGGAGTCATTCACTGGTTGGCGTGATGATATCCAGTGTCCCTCTGCCCCCTTCTACCCCCAGCCCCATTTTACTGTAGCATTGCATCTGTGTCCTGTTGCCATTTCTGTTAACCTTCAGGTATTAAACTTGCTGCATATCTTGA
>NM_001308347.2
GAGTCGACGGCTGGAGAGAAGCCGGGAGCGAGCCCAGGCGGCAGTCTTGATTCCCTTTTGGCCAGCAGTTTTTAGGTCTGTCAGTACTGCACTGCAAGAATGGCAGATTTTGGGATCTCTGCTGGCCAGTTTGTGGCAGTGGTCTGGGATAAGTCATCCCCAGTGGAGGCTCTGAAAGGTCTGGTGGATAAGCTTCAAGCGTTAACCGGCAATGAGGGCCGCGTGTCTGTGGAAAACATCAAGCAGCTGTTGCAATGTTTAGTCCCAGGAAGCACCACTCTGCACAGTGCTGAGATTTTGGCTGAAATCGCCCGGATCCTTCGGCCTGGTGGATGTCTTTTTCTGAAGGAGCCAGTAGAGACAGCTGTAGATAACAATAGCAAAGTGAAGACAGCATCTAAGCTGTGTTCAGCCCTGACTCTTTCTGGTCTTGTGGAAGTGAAAGAGCTGCAGCGGGAGCCCCTAACCCCTGAGGAAGTACAGTCTGTTCGAGAACACCTTGGTCATGAAAGTGACAACCTGCTGTTTGTTCAGATCACAGGCAAAAAACCAAACTTTGAAGTGGGTTCTTCTAGGCAGCTTAAGCTTTCCATCACCAAGAAGTCTTCTCCTTCAGTGAAACCTGCTGTGGACCCTGCTGCTGCCAAGCTGTGGACCCTCTCAGCCAACGATATGGAGGACGACAGCATGGATCTCATTGACTCAGATGAGCTGCTGGATCCAGAAGATTTGAAGAAGCCAGATCCAGCTTCCCTGCGGGCTGCTTCTTGTGGGGAAGGGAAAAAGAGGAAGGCCTGTAAGAACTGCACCTGTGGCCTTGCCGAAGAACTGGAAAAAGAGAAGTCAAGGGAACAGATGAGCTCCCAACCCAAGTCAGCTTGTGGAAACTGCTACCTGGGCGATGCCTTCCGCTGTGCCAGCTGCCCCTACCTTGGGATGCCAGCCTTCAAACCTGGGGAAAAGGTGCTTCTGAGTGATAGCAATCTTCATGATGCCTAGGAGGTTCCTGACATGGGACCCATCTGCTCCTCCAGCCAACTCCTGTCCCTCACATCCCACCATGGTGGCTCCTCCCACCTCCTCTGGATTTGTTCACTCTGAGATCTGTTTGCAGAGTGGGTGCTTAGCAGACAGAGTGAAGCTGGCTGGGGGGCACAGTGGTGTGTAGTGCTGCTGTGTATCAAAAGACCAAGGTATTATGGGACCTGGTTTCAGAATGGGATGGGTTTCTTCACCTCATGTTAAGAGAAGGGAGTGTGTCCTGAAGAAGCCCTTCTTCTGATGTTAAAATGCTGACCAGAACGCTCTTGAGCCCAGGCATCGTTGAGCATTAACACTCTGTGACAGAGCTGCAGACCCCTGCCTTGAGTCTCATCTCAGCAATGCTGCCACCCTCTTGTCTTTCAGAGTTGTTAGTTTACTCCATTCTTTGTGACACGAGTCAAGTGGCTCACAACCTCCTCAGGGCACCAGAGGACTCACTCACTGGTTGCTGTGATGATATCCAGTGTCCCTCTGCCCCCTTCCATCCCCAACCACATTTGACTGTAGCATTGCATCTGTGTCCTGTTGTCATTTATGTTAACCTTCAGGTATTAAACTTGCTGCATATCTTGACATATCTTGAGATTCTGCATGTCTTGTAAAGAGAGGGGATGTGCATTTGTGTGTGATGTTGGATAGTCATCCACGCTCAGTTTGGACCATTGGAGGAACTTAGTGTCACGCACAAATGGGGCTATTCCTACGCTTAGAATAGGGCTTGTCTGCCCACTTTAGAAGAGTCCAGGTTGGTGAGCATTTAGAGGGAAGCAGGGCAGAACTCTGAACGACAATACGTCTCTCTGAGCAGAGACCCCTTTGTTCTTGTTATCCACCCATATGGACTTGGAATCAATCTTGCCAAATATTTGGAGAGATTGTGTGGATTTAAGAGACCTGGATTTTTATATTTTACCAGTAAATAAAAGTTTTCATTGATA

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