Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SDF2P1
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:75114231-75115117  UCSC
Coordinates (T2T) chr15:72984213-72985099  UCSC
Coordinates (hg19) chr15:75406572-75407458  UCSC
Strand +
Parental Sequence NM_006923.4
Parental seq. overlap 736 bp
Parental seq. overlap (%) 56.1%
Genomic Region Intergenic
Retrocopy Summary SDF2P1, located on chr15:75114231-75115117, is a retrocopy of the parental gene SDF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SDF2
Full Name stromal cell derived factor 2
Also known as -
Coordinate chr17:28648346-28662135
Strand -
Gene summary The protein encoded by this gene is believed to be a secretory protein. It has regions of similarity to hydrophilic segments of yeast mannosyltransferases. Its expression is ubiquitous and the gene appears to be relatively conserved among mammals. Alternate splicing results in both coding and non-coding variants. A pseudogene of this gene is located on chromosome 15. [provided by RefSeq, Dec 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SDF2P1
Bonobo Pan paniscus SDF2P1
Gorilla Gorilla gorilla SDF2P1
Orangutan Pongo abelii SDF2P1
Gibbon Nomascus leucogenys SDF2P1
Green monkey Chlorocebus sabaeus SDF2P1
Crab-eating macaque Macaca fascicularis SDF2P1
Rhesus Macaca mulatta SDF2P1
Baboon Papio anubis SDF2P1
Golden snub-nosed monkey Rhinopithecus roxellana SDF2P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SDF2P1
GGAAGATCTGGGGCTCCGAATCCAGCTAGGATGGCTGTGGTTCCGCTACTGCTGTCTGGGGGTTTGTGGAACACCGTGGGAGCGTCCAATCTGGCTGTTACTCGCGGCTCTATGGTGAAGCTGCTCGAAATGCACTACAGTGTCCATCTGCAGTCACACGATGTGCTCTATGGGTCAGGTACTGGGCAGCAGTCAGTGACAAGTGTAACCTCCATGGATGACAGCAACAGTTACTGGAGAATATGGGTAAGATCACCACAGCTGGTGAGAGGGGAACCCCCATCAAGTGCTGCCAGCCCATCCGGCTGACACATGTCAACACTGGCTGAAACCTCCACAACTTTCTGAAAACCAGGAAGTGGGTGCTTTTGGTGAGGAAGGTGAAGGTAGTCACCTGGATGACTGGACCATACTCTGTAACGGGCCCTACTGGGTGAGAGATGGTGAGGGGTGGTTCAAACATTCTTCCATTGAGGAACCGCTGTCTGTCACAGGAGAACGATATGGTGGACCCATCAGTGGGCAAAAAGAGACGCATGGTCTGGCCTAGCCAAGCCGAGCAACGACTGGAAAGCCATGGAAGGCATCTTCATGAGGCCCAGTGAGTTGTTGAcTCTGAGCCACTGTCACTACACAGTTTGTAGACATCTGTGCTGCTTCACCTTGGGATCCCTGCCACAAGTTCCCCAGGAGTGGCCATGTTACTACTGAGATGAAGATGTGCAATGGAAAACAGTGGCTGTGTTCACAAGCTCCAGCCCTGCACATTTGAATTGGCTGCTCTCCCAGACTTGGGTCAGTACTTTCTGAGTAGAGGACTTGCTGGTGACAGGGTGGATGCTTTTTATT
>NM_006923.4
GAAGATTTGGGGCTCCGCGATACAGTTAGGATGGCTGTAGTACCTCTGCTGTTGTTGGGGGGTTTGTGGAGCGCTGTGGGAGCGTCCAGCCTGGGTGTCGTTACTTGCGGCTCCGTGGTGAAGCTACTCAATACGCGCCACAACGTCCGACTGCACTCACACGACGTGCGCTATGGGTCAGGTAGTGGGCAGCAGTCAGTGACAGGTGTAACCTCTGTGGATGACAGCAACAGTTACTGGAGGATACGGGGGAAGAGTGCCACAGTGTGTGAGAGGGGAACCCCCATCAAGTGTGGCCAGCCCATCCGGCTGACACATGTCAACACTGGCCGAAACCTCCATAGTCACCACTTCACTTCACCTCTTTCTGGAAACCAGGAAGTGAGTGCTTTTGGTGAGGAAGGTGAAGGTGATTATCTGGATGACTGGACAGTGCTCTGTAATGGACCCTACTGGGTGAGAGATGGTGAGGTGCGGTTCAAACACTCTTCCACTGAGGTACTGCTGTCTGTCACAGGAGAACAATATGGTCGACCTATCAGTGGGCAAAAAGAGGTGCATGGCATGGCCCAGCCAAGTCAGAACAACTACTGGAAAGCCATGGAAGGCATCTTCATGAAGCCCAGTGAGTTGTTGAAGGCAGAAGCCCACCATGCAGAGCTGTGAATCTAGAGGCTCTGAGCCACTGTTAACGCACAATGTTCACAGACATCTGTTGCTGCCTCACCTTGGGATCCCTGCCACAAGTTCCTTGGGCAGTGGCCATGTCACCATTGAGATGAAGATATACAACAGAAAATAGTGGCTGTGTTTGGAAGCTTCAGCCCTGCACATTTGAACTAGTCACTCTCCCAGACTTGCGTGGGTCAGTTCTTTCTGAGTAGAGGACTTGCTGGTAAAGGGGCAGATGCTTTTTATTAGTACTGATAAAACAAACTGAGGGAAACATCCCTCTTAGCTGGGAAACTTTTACTCTTCAGGAGCTTGGCATCATGGACTGTTAATGTATGTGATTTTCCCCCTATTTTCTCTCTCCAAAATGATAAAAACAATAATTTTATTATGAGTCACTGTGTTGTTATTTATTAGGTGTGCTATTTCATTAGCTGCTTAATCCTTTGAGTCCTAAGACTCTTTGGAGACGCTATGAAGCTCCAATGTGGGCCCTTTTAAGAGCTTTTCTTGCATACAAACCTTTTCTCCCTCTACTTTGACTTCTCTCCAGGCATCTCATCTTTAATAGATCTTTGACTAATTATAGCTAAAAACTCTCAGAGAATACAGCATAATAAATAGCCAGTGAAATGTT

Publications

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