Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TFDP1P3
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:79556568-79560673  UCSC
Coordinates (T2T) chr15:77419944-77424049  UCSC
Coordinates (hg19) chr15:79848910-79853015  UCSC
Strand -
Parental Sequence XM_017020720.2
Parental seq. overlap 1467 bp
Parental seq. overlap (%) 45.2%
Genomic Region Intergenic
Retrocopy Summary TFDP1P3, located on chr15:79556568-79560673, is a retrocopy of the parental gene TFDP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TFDP1
Full Name transcription factor Dp-1
Also known as DILC|DP1|DRTF1|Dp-1
Coordinate chr13:113584693-113641473
Strand +
Gene summary This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TFDP1P4
Bonobo Pan paniscus TFDP1P3
Gorilla Gorilla gorilla TFDP1P3
Orangutan Pongo abelii TFDP1P3
Gibbon Nomascus leucogenys TFDP1P2
Green monkey Chlorocebus sabaeus TFDP1P3
Crab-eating macaque Macaca fascicularis TFDP1P3
Rhesus Macaca mulatta TFDP1P3
Baboon Papio anubis TFDP1P3
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TFDP1P3
AATTCGACTTTCTAAACAGCCCCAAGCAAACAGCAGAATTCGACTTTCTAAACAATAAACACCATCAACCTTATTGACTTTATTGTCCCTTAAATTATATTGGCTGTTGTGATTCCATCAAGTTTATACACTCTTTTCTCTCCCTATTTTGCAGCAACAAATTGCAAAGTGCTTTTGTTTGGTTTTGTTTGGTTAAAGCTTATTGCCATGCTGATGCGGCTATGGAGACTATCTGGAAGGCTTGGAATGGTTTATTGCTTATGGTAAAATTTGCCTGATTTCTTACAGGCAGTGTTCGGAAACCTTTTATTATATAGTTGTTTACATACTTATAATTCTATCACTTAAAGACATGTACTGAAACAAATGTATTTGTTTCATAAGCATCTTCCTGTAATCTATTATAAAATTGAAATTAAATATAGAGAATGTTTTAACAATTTTTTAACTCAAAATTTGTCAATAATTTTTAATAGTTCTTTTTTTATAAAAAGAAAAAGGAATTTAAGGACAGGCCATAGTCTCTTTTAAAATTTATTCACAAAACCCATTAACTGCGCAGTTGCTATTAGCTGCCTGTTCTAAAATGATAGTCTTTTTATTGAAACACCAACTTTTCTGTAATATTTTATGGAATATAAAGAGACTTTAATTGTTTGACTTGTTTAACTTGGCACTGTTAGTTTTTATTAATAAAACGGTCATGGGCATTTaTTCTTTAAGTGCGGAGTTCATTTTTGCCCCTGAACAGTTTTTGCTGAGTTTGCTGAAGAAATTGTATTTCATCCACATCCATGAAAATGAAACGCCCTCCTGTTGTGGATGGTGAGCACCTGATGCCTTTTATTTGCCGTGAGTTTGGACGGCGCCCCCGCTGGCAGATGGCGAGACTCTGTGGAGTTTGTTCAGTGGTATGGTGTCCAAGCAAACAGCATAATTCGACTTTCTAAACAGCCCCAAGCAAACAGCAGAATTCGGCTTTCTTCATCATCATCAACACCAGCAAGAAGACGGTCATCGACTGCAGCATCTCCAACGACAAATTCGACTATCTGTTTAATTTTGACAACACATTTCAAATCCACGATGACATAGAAGTGCTGAAGCGGGTGGAGTCCGGGAGCTTCTCTGCTGAGGACCTTAAAATGGCCAAAAGTCTGGTCCCAAAGACTCTGGAGCGGTAAGTGACAGAAATGGCTCAGGGAACTGTGGGAGGCGTGTTCATCACGATGGCAGGTTCCACGTCTAACGGCACGAGGTTCTCTGCCAGTGACCTGACCAATGGTGCAGATGAGACGCTGGCCACAAAGTTCCAATGGGTCTCAGTACAGCAGCTCCAGGGTGGAGACCCCGGTGTCTTACGTCGGGGAGGACGACGAGGAGGATAATGACTTCAACGAGAATGAGGAGGACGACTGACATCCTCCCCACTTCAAATTCAGCTTCAGGAAAACGTTGAGGGAAAAGATTTTTTTTTTTAATGTGGGTTTTCTGTTTCCTTTTGGCCTACTCCCAAGAAAATATTGGTAAGCTATTGAATTTAGATATGCACCTCTGATAAGCAAGGATTGTTTCCCGTAGGATTAGGATGTGCTGTGGATGTGTGTTTTGATACCAGTGTGCAGATGCAGAGTGTTGGACCGGGCAGCCAGAAAAATCATTTTTCTTCTCTGGGAAGGTGAACATTTGTAGCATTGATTTCCCGGATCTGGTAACATGGCAAAAGATGCCGGTCTAATTGAAGCCAATGGAGACCTCAAGGTCTTCATAGACCAGAACCTTAGTCCTGGAAAAGGCGTGGTGTCCCTCGTGGCCGTTCACCCCTCCACCGTCAACCCGCTCGGGGAGCAGCTCTTGGCAAAAACCTCTGGACAGTCCAATGTCAACATTGCCCAGCAAGTGGTAGTTGGTACACCTCAGAGACCGGCAGCGTCAAACGCCCTGGGGGTAGGAAGCCCACACACCCCAGCACTCACTTTGCCTCTCAGAACCAGCCTTCCGACTCCTCACCTTGGTCTGCCGGGAAGCGCAACAGAAAAGGAGAGGAGAATGGCAGGGGCCTGCGGCATTTCTCCATGAAGGTCTGCGAGAAGGTGCAGAGGAAAGGGACCACTTCCTACAACCAAGTGGCGGATGAGCTGGTCGCGAAGTTCAGTGCTGCCGACAACCACATCTTACCAAACGAGTCAGCTTGTGACCAGAAGAACATAAGACGGCGCGTCTGCGATGCCTTAAATGTGCTGAGGGCCGTGAGCATCATCTCCAAGGAGAAAAAGGAGATCAAGTGGATTGGTCTGCCCACCAACTCGGCTTAGGAATGTCAGAACTTAGAGGTGGAAAGACAGAGGAGACTTGAAAGAATAAAACAGAAACAGTCTCAACTTCAAAACTTATTCTACAGCAAATTGCCTTCAAGAACCTGGTGCAGAGAAACCGGCACGCGGAGCGGCAGGGCGCCGCTCg
>XM_017020720.2
CCGCGTCCCGGCGCCACTCGGCCCAGGGCAGGGACCCCGCCACGGCCGGGACCGCCCGGCCCGGCCCCAGCCCGCGCCTCTCCGCGCCGCCCCGCGCTCCGCACCGCGCCCTCTCCGCGTCCCCGCCCGCGCGGCCGGACCGGGCAGCCAGAAAAATCATTTTTCTTCTCTGGGAAGGTGAACATTTGTAGCATTGATTTCCCGGATCTGGTAACATGGCAAAAGATGCCGGTCTAATTGAAGCCAACGGAGAACTCAAGGTCTTCATAGACCAGAACCTTAGTCCCGGGAAAGGCGTGGTGTCCCTCGTGGCCGTTCACCCCTCCACCGTCAACCCGCTCGGGAAGCAGCTCTTGCCAAAAACCTTTGGACAGTCCAATGTCAACATTGCCCAGCAAGTGGAAGCGCAACAGGAAAGGAGAGAAGAATGGCAAGGGCCTACGGCATTTCTCCATGAAGGTCTGCGAGAAGGTGCAGAGGAAAGGGACCACTTCCTACAACGAAGTGGCAGACGAGCTGGTTGCGGAGTTCAGTGCTGCCGACAACCACATCTTACCAAACGAGTCAGCTTATGACCAGAAAAACATAAGACGGCGCGTCTACGATGCCTTAAACGTGCTAATGGCCATGAACATCATCTCCAAGGAGAAGAAGGAGATCAAGTGGATTGGTCTGCCCACCAACTCGGCTCAGGAATGTCAGAACTTAGAGGTGGAAAGACAGAGGAGACTTGAAAGAATAAAACAGAAACAGTCTCAACTTCAAGAACTTATTCTACAGCAAATTGCCTTCAAGAACCTGGTGCAGAGAAACCGGCATGCGGAGCAGCAGGCCAGCCGGCCACCGCCACCCAACTCAGTCATCCACCTGCCCTTCATCATCGTCAACACCAGCAAGAAGACGGTCATCGACTGCAGCATCTCCAATGACAAATTTGAGTATCTGTTTAATTTTGACAACACATTTGAAATCCACGATGACATAGAAGTGCTGAAGCGGATGGGCATGGCTTGCGGGCTGGAGTCGGGGAGCTGCTCTGCCGAAGACCTTAAAATGGCCAGAAGTCTGGTCCCCAAGGCTCTGGAGCCATACGTGACAGAAATGGCTCAGGGAACTGTTGGAGGCGTGTTCATCACGACGGCAGGTTCCACGTCTAACGGCACAAGGTTCTCTGCCAGTGACCTGACCAACGGTGCAGATGGGATGCTGGCCACAAGCTCCAATGGGTCTCAGTACAGCGGCTCCAGGGTGGAGACTCCGGTGTCCTacgtcggggaggacgacgaggaggacgatgacttcaacgagaatgacgaggacgactgacgTCCTCCCCACTTCAGATTCGGCTTCAGGAAAACGTTTAGCGAAAAGAAACTTTTTTTTTAATGTGGGTTTTCTGTTTCCTTTTGGCCTACTCCCAAGAAGATATTGGTAAGCTATTGAATTTAGATATGCACCTCTGATAAGCAAGGATTGTTTCCCGTAGGATTAGGACGTGCTGTGGATGTGTGTTTTGATACCAGTGTGCTGATGCAGAGCGTTTATTTACTTGTTAGGATTTTGTGTTTTCATTTGCTATTTTTCTTTAAGTGCAGAGTTCATTTTTGCCCCTGAAAAGTTTTTGCTGAGTTTGCTGAAGAAATTGTATTTCAACCACATCCATGAAAATAAAACACCTCCTGTTGTGGATGGTGAGCCCCTGATGCCGCTTATTTGCCGTGAGTTTGGACGGCACCCCTGCTGGCGGATAGCAAGACTCTGTGGAGTTTGTTCAGTGGTACGGTGTCCAAGCAAACAGCAGAATGCAACTTTCTAAACAGCCCCAAGCAAACAGCAGAATTCAACTTTTTAAACAATAAACACCATCAACCTTATTGACTTTATTGTCCCTTAAATTATATTGACTGTTGTGATTCCATCAAGTTTGTACACTCTTTTCTCTCCCTGTTTTGCAGCAACAAATTGCGAAGTGCTTTTGTTTGTTTGTTTTCGTTTGGTTAAAGCTTATTGCCATGCTGGTGCGGCTATGGAGACTGTCTGGAAGGCTTGGAATGGTTTATTGCTTATGGTAAAATTTGCCTGATTTCTTACAGGCAGCGTTTGGAAACCTTTTATTATATAGTTGTTTACATACTTATAAGTCTATCATTTAAAGACATGTACTGAAACAAATGTATTTGTTTCATAAGCATCTTCCTGTAATCTATTATAAAATTGAAATTAAATATAGAGAATGTTTTAACAATTTTTTAACTCAAAATTTGTCAATCATTTTTAATAGTTCTTTTTTTATAAAAAGAAAAAGGAATTTAAGGACAGGCAGTAGTCTCTTTTAAAATTTATTCACAAAACCCATTAACTGCACAGTTGCTATTAGCTGCCTGTTCTAAAACGATAGTCTTTTTATTGAAACACAAATAAACTTTTCTGTAATATTTTATGGTATATAAAGAGACTTTAATTGTTTGACTTGTTTAACTTGGCACTGTTAGTTTTTATTAATAAAACGCGCATGGGCATTTTAAACAA

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