Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NIFKP10
Plot displaying the genomic locations of a retrocopy (in chr15) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr15:90284322-90285588  UCSC
Coordinates (T2T) chr15:88040319-88041589  UCSC
Coordinates (hg19) chr15:90827554-90828820  UCSC
Strand -
Parental Sequence NM_032390.5
Parental seq. overlap 583 bp
Parental seq. overlap (%) 29.2%
Genomic Region Intergenic
Retrocopy Summary NIFKP10, located on chr15:90284322-90285588, is a retrocopy of the parental gene NIFK. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NIFK
Full Name nucleolar protein interacting with the FHA domain of MKI67
Also known as MKI67IP|Nopp34
Coordinate chr2:121726945-121736875
Strand -
Gene summary This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NIFKP5
Bonobo Pan paniscus NIFKP6
Gorilla Gorilla gorilla NIFKP2
Orangutan Pongo abelii NIFKP8
Gibbon Nomascus leucogenys NIFKP1
Golden snub-nosed monkey Rhinopithecus roxellana NIFKP6
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NIFKP10
AGGCCAGGTTTTACATAAGAAGCAGCGAAAGGTTTTAGGCACTCCTGACACTCCTGAGAAGACTGTGGATAGCCAGGGCCCCACACCGGTTTGTACCTCAACATTTTTGGAGAGACGAAAATCTGAAGTGGCTGAAATGAACAATGATGATGAAGATAACAAAATAGTTTTCAAACAGCCCATATCCTGTGTAAAAGAAGAAATACAAGAGACTCAAACACCTACACATTCACAGAAAAAAAGATGAAGAAAAAGCAATTAGTGATTTTCAATGTATTATGTATAATATTTCTTCTGAAAAACATAATATTTTTATGAGGCTTTTGGCATGGCGGCCTTTTCCGGCCCGGCTGGGCCAATCCTGTCGCTGAACCCACAGAAAGATGTGGGTTTCAGAAGGAGGTGGCACAGGTTCTGCGCATAACCCAGCGAGAAAAACAAGAACAACTTACTCCTGGAGTGGTCTACGTGTGCCACCTACATAACCTACTGAACGAAACCCAGATTCTTTCATATTCCTCCCAGTGTGGCACTGTTACAAGCTTCAGACTATCCAGACAGAAAAGGACTGGAAATAGCAAAGGCTATGCATGTGTGGAGTATGAGTCTGAGGATGTTGCCAAGATAGTTGCTGAAACAATGAACAACTACCTGTTTGGCGAAAGACTCTGGGAGTGTCATTTTATGACACCTGAAAAAGTACAGAAAGAACTCTTTAAAGACTGGGATATTCCGTTTAAGCAGGCATCATATCCATCAGTGAAACGGTATAATCAGAATCGGCACTTACACAAAAGCTGTGGGTGGAGGGGCGATTTAAAAAGAAAGATTACTCAAGAAGAAATTAGCTTAAAAAGGAATTGATTATGATTTTCCTTCTTTGATTTTACAGAAAACAGAAAGTATTTCAAAAACGAATCATCAGACGTCTACAAAGGGCCAGGTTTg
>NM_032390.5
GTGGTTAGCGTCGGCGGCTTTTGGCATGGCGACTTTTTCTGGCCCGGCTGGGCCAATCCTGTCGCTTAATCCGCAGGAAGATGTCGAGTTTCAAAAGGAGGTGGCGCAGGTTCGCAAGCGCATAACCCAGCGAAAAAAACAAGAACAACTTACTCCTGGAGTAGTCTATGTGCGCCACCTACCTAACCTACTTGACGAAACCCAGATCTTTTCATATTTCTCCCAGTTTGGCACTGTGACACGGTTCAGGCTGTCCAGAAGTAAAAGGACTGGAAATAGCAAAGGCTATGCATTTGTGGAGTTTGAGTCTGAGGATGTTGCCAAAATAGTTGCTGAAACAATGAACAACTACCTGTTTGGTGAAAGACTCTTGGAGTGTCATTTTATGCCACCTGAAAAAGTACATAAAGAACTCTTTAAAGACTGGAATATTCCATTTAAGCAGCCATCATATCCATCAGTGAAACGGTATAATCGGAATCGGACACTAACACAAAAGCTACGGATGGAGGAGCGATTTAAAAAGAAAGAAAGATTACTCAGGAAGAAATTAGCTAAAAAAGGAATTGACTATGATTTTCCTTCTTTGATTTTACAGAAAACGGAAAGTATTTCAAAAACTAATCGTCAGACGTCTACAAAAGGCCAGGTTTTACGTAAGAAGAAGAAAAAAGTTTCAGGTACTCTTGACACTCCTGAGAAGACTGTGGATAGCCAGGGCCCCACACCAGTTTGTACACCAACATTTTTGGAGAGGCGAAAATCTCAAGTGGCTGAACTGAatgatgatgataaagatgatgaAATAGTTTTCAAACAGCCCATATCCTGTGTAAAAGAAGAAATACAAGAGACTCAAACACCTACACATTCACGGAAAAAAAGACGAAGAAGCAGCAATCAGTGATTTTCAATGTATTATATTTCTTTTGAAAAATATAATATTTTTATGAGAGTGGACTTTGTATTTCACTAGGTACAATGGAATACAACCTTTGACAAGATTTTCAGAGGAAAAATACACTGTTTGGTCAAGTTAAGGAAAGCAGTGTGTAATTTTGGATTGCCTGCCCTTGGCTGAAATACAGGGGTGCATACCATCTTGCAGTGGCTTGGCTGACATTGCCTCTTTGTCCTGGCCTCTAGTTTTCTTTTGATATTTCATAGCTCTCCTTAGTTTACTCTGCCTGGATAGAAAGTTGACCACTAACTGCAGGTTTAAGTACTAAACTGCAGCCTTTTCTGTCGCCAGCAATTAAAGACCACCAATCTTGTTTGTCCATCTACATGGTTTGTCGGGGACATTTAACTCATGGAGGTGCTTTAGATTTCAACATCAGATGGTTGAAGCTGGAAGTTTAATTATATGTAGAGTGAGAAGGCAGTTCCAGTTTTAGCACAGATTTGTTTATGTGTTCAGATTTTAATAGAGATTCAAAAATGACTCATTTTTACCAATAATGTTAAATTAGTTTTGGTTGTGCTAGCATGAATTAATAACCACCATTTTATACCAGTATCATCAGTGAAGAATTGTATTTCAAGATTCAAACAATAACCAGCAATTAAACTTTTTTCTACAATGTATTTGTTTGCGAGTAGGACTTGGGAGTCATTGGGAAAAAAAAATAATAAATTTTCCCCTTCATTAACGAATTCAGACTCATTAAAAACATTGCCATCAGA

Publications

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