Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RPL7P46
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:11026726-11028542  UCSC
Coordinates (T2T) chr16:11063006-11064822  UCSC
Coordinates (hg19) chr16:11120583-11122399  UCSC
Strand +
Parental Sequence NM_198486.5
Parental seq. overlap 1453 bp
Parental seq. overlap (%) 38.1%
Genomic Region Intragenic (CLEC16A)
Retrocopy Summary RPL7P46, located on chr16:11026726-11028542, is a retrocopy of the parental gene RPL7L1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RPL7L1
Full Name ribosomal protein L7 like 1
Also known as dJ475N16.4
Coordinate chr6:42879616-42889900
Strand +
Gene summary Enables RNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within blastocyst formation. Predicted to be located in nucleolus. Predicted to be part of cytosolic large ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RPL7L1P25
Bonobo Pan paniscus RPL7L1P27
Gorilla Gorilla gorilla RPL7L1P21
Orangutan Pongo abelii RPL7L1P23
Gibbon Nomascus leucogenys RPL7L1P22
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RPL7P46
TGGGAAGCACTTTATTGTCCACAGCCAAGCTGCTTGTGATGAAACTGTAACTTACAAGAAAAGGGCTGGGTTTTAAAAATGACACAGGCTCTAAAAACCCTGGAAGCGGTGCAACTTTTGGCAGGAATGGGGGTTAGCAGGACCTCAATGGCTCACTATGGCTAAGTGAACGCTGACTGGGTCCTCCAGCGTGAGCTAGAACAGACGTCTCTATGGTCAAGTAAACAGCGCGCGTGCTGTCTTTCCCATGTGGTGGGGTTGCGCATGATCAGTAGCTGCACCACTAGAAAGATGGCGGAGGAAGAGCAAAGAAAAATCCCTTTGGTTCCAGAAAATCTCCTGAAAAAGAGGAAGGCTTATCAGGCACTCAAAGCCACCCAGGCAAAGCAGGAACTTTTGGCAAAGAAGGAGCAGAAGAAAGGAAAAGGGCTCAGGTTTAAGCTACTGGAATCATTCCTACATGATTACTGGCAGCAGAAACCTGACAAGGTGCATCTCAGACGACTAGAAGTGAAACCTCATGCCGTGGAATTGCCAGATAAACATTCCTTGGCCTTTGTTGTACGCATCGAAAGGATTGATGGCGTGAGTTTACTGGTGCAGAGAACCATTGCAAGACTTTGCCTAAAGAAAATTTTTAGTGGTGTCTTTGTAAAAGTCACCCCCCAGAATCTACAAATGCTGCGTATAGTGGAAACTTATGTGACCTGGGGATTTCCAAATCTGAAGTCTGTCCGAGAACTCATTTTGAAACGTGGACAAGCCAAGGTCAAGAGTAAGACCATCCCTCTGACAGACAACACAGTGATTGAGGAGCACCTGGGGAAGTTTGGCATCATTTGCTTGGAAGACCTCATTCATGAAATTGCATTCCCAGGGAAGCATTTCCAGGAGATCTCATGGTTCTTGCGCCCTTTCCACCTCTCAGTGGCCCATCATGCTACCAAAAATAGAGTGGGCTTCCTCAAGGAGATGGGCACACTTGGCTATCGGGGTGAACGCATCAATCAGCTCATCCGCCAGCTGAACTAGACCCAGGTGCCAAACTGCAGTATATTTTTGATCAATGAAGTGGAAGCATGTGTTTTGTTGTTTTGGGAATTTTTATCAAGTGTCTTCAGAGAAGATTATTTCCTGCTCTGTCTTCAAAAACTGGAAAGGAAGGGTCAAAGAAAAGACAGTAGCTaGACAGTAGCTTATGTTCATGTCAAGCACCTCTCATCAGAGTCTAGTTCCAAGGAAAAATTCCAGTGTTTTCTACATTGGGTGCTGCGTCGTCTGAAATCGGCACATTCCATGGAGGAAGGAGTCCTGCTTTGTTGCATCTATCCTAGGGTTTAATGTTGGTAAATGAGTCACTCTAGCATTTGTACAAGGCTCCCTAAGACTCCTGCAGCAGTCGACCAAGCCCAAGGACATAATTGAATCTGGAGAGTCCTGGAGCCTTGTTTTGAAAAAGACTTGAAATACACATAGGAAGAAAGGCATAAAAATAAAGGTTCACTTGTCTCTGCTGTG
>NM_198486.5
GTAGCTAGGAGCGGACGCCATAGGTGCATTGTGGGAAGCACTTTGCTGTCCACAGCCAGGCCGCTTGTGATGAAACTGTAACTTACAAGAAAAGGGCTGGGTTTTGAAAATAACACAGGCTCTAAAAACCCTAAGAAGCGGTGCAACTTTTGGCAGGAATCGGGGTTAGCGGGACCTCAAGGGCTCACTGCGGCTAAGTGAACGCTGACTGGTCCTCCAGCGTGAGCTAGAACAGACGTCTCTATGGTCAAGTAAACAGAGCGTGTGCTGTCTTCCCCATGTGGTGGGGTTGCGCATGATCAGTAGCTGCACCACTAGAAAGATGGCGGAGCAAGAGCAAAGAAAAATCCCTTTGGTTCCAGAAAATCTCCTGAAAAAGAGGAAGGCTTATCAAGCCCTCAAAGCCACCCAGGCAAAGCAGGCACTTTTGGCAAAGAAGGAGCAGAAGAAAGGAAAAGGGCTCAGGTTTAAGCGACTGGAATCATTCCTACATGATTCCTGGCGGCAGAAACGTGACAAGGTGCGTCTCAGACGACTAGAAGTGAAACCTCATGCCTTGGAATTGCCAGATAAACATTCCTTGGCCTTTGTTGTACGCATCGAAAGGATTGACGGCGTGAGTTTACTGGTGCAGAGAACCATTGCAAGACTTCGCCTAAAGAAAATTTTTAGTGGTGTCTTTGTAAAAGTCACCCCCCAGAATCTAAAAATGCTGCGTATAGTGGAACCTTATGTGACCTGGGGATTTCCAAATCTGAAGTCTGTCCGAGAACTCATTTTGAAACGTGGACAAGCCAAGGTCAAGAATAAGACCATCCCTCTGACAGACAATACAGTGATTGAGGAGCACCTGGGGAAGTTTGGCGTCATTTGCTTGGAAGACCTCATTCATGAAATTGCCTTCCCAGGGAAGCATTTCCAGGAGATCTCATGGTTCTTGTGCCCTTTCCACCTCTCAGTGGCCCGTCATGCTACCAAAAATAGAGTGGGCTTCCTCAAGGAGATGGGCACACCTGGCTATCGGGGTGAACGCATCAATCAGCTCATCCGTCAGCTGAACTAGACCCAGGTGCCAAACTGCGGTAAATTTTTTATCAGTGAAGTGGAAGCATGTGTTTTGTTTTGGAAATTTTTATCAAGTATCTTCAGAGAAGATTATTTCCTGCTTTATCTTCAGAAACTGGAAAGGGTCAAAGAAAAGACAGTAGCTggccggtcgtggtggctcatgcctgtaatcccaacacttagggaggctgaggtgggcagatcacctgaggttgggagttcgagaccagcctgaccaacatggagaaatgccatctctactaaaaatacaaaaattagccgggcatggtggcacgtgcctgtaatcccagctactcaggaggctgaggcaggagaatcgcttgaacctgggaggtggaagttgcagtgagctgagatcacgccattgcactccagcctgggcaacaagcgaaactctgtctcaaaaaaaaagaaaaGACAGTAGCATATGTTCATGTCAAGCACCTCTCATCACAGTCGAGTTCCAAGGAAAAATTCCAGTGTTTTCTGCATTGGGTGCTGTGTCATCTGAAATCGGCACATTCCATGGAGGAAGGAGTCCTGCTTTGTTGCATGTATCCTAGGGTTTAATGTTGGTAAATGAGTCACTCTAGCATTTGTAGAAGGCTCCCTGAGACTCCTGCAGCAGTCGACCAAGCCCAAGGACATAATTGAATCTGGAGAGTCCTGGGGCCTTGTTTTGAAAAAGACTTGAAATACACATAGGAAGAAAGGCATAAAAATAAATGTTCACTTGTCTCTGCTGTGAGTATGTGTTCCAACTTTTCAGTGATGGCTTTGAGAATTCTCAAACTTGACTGGCTCTAAGTGTATCTGGTGGCTTTTGTATCGTAACCTGAAACTGGCTTAGTACTTTTTCCTAAAAGCTCAGGATTTGAGAATGAggaccccttcgccaggaaaacatgtatacactcaaaattttgcttgcagttctagggtgtttagacccTTCTCAGATACCTGTGCATCTTATGGGttttgtttttctctttgagacagtctcaccctgttgcccaggctggagcgcagtggcatgatctcagctcattgcagcctccacctcctgggttcaagtgattctgcctcagccccttgatcagctgggattacatgcatgtaccaccacacccagctaattcttgtatttttagtagagatggagacagagtttcaccatgtaggccaggctagtctcaaactcctgacctcaagtgatccacaagcctgggcctcccaaagtgctgggattacaggcatgagcaactgcgcccagcTCTTGTGTACCTTATGTGAGGAAGTCCTGCTCAATCAGGATCGGTCACGCAGGCCCTGATCTTGCTACTCTGGTTCCATGTCCTATGGAAGACCAAAGTTTACCAAGATAGATTTTTCCCTTCATAGTGGCAGATAGTGTTAACCCCTGCACCATCTGTAACTCAGAAATCCCCACCATTTCTTCCCCTGGGCTTCAGAATAGAATTGCCTGGTTTCTCTGATGATCAGCATGGTTCCTTAAAACCCAAATCAGCAAGGAATGAACAATTTTGTTTGGCATGGATGAAATTAGCACTGTTTGGCTCGTTAGGCCCCAGGCAGGCAGGCACCTTAATTTTTTCCTTGCATATTCTAGTCTTCAGAAGCATTGCCTTTTGTCCTACTGGTAGTGACATAGACCAATAACAGGGCATCTGGGGATTTTAATCCTGAAAACAGTGAGTCTGATACTGCTTGTGTTTTTCATCAGTGTCCACCCCAAGTGGGTCTTCCTGCTATTCTCTTCACTTAGTTGCCCCTCACTTGCCATCTGAGCAATTGGCAAGGATGTGCCAGGCCTAGGTTAAACTTGGAAACATGCTTGACCATTCTATTCCCTGGTCCTTTAAGATCAGTTTGGCTGCAATTTTGGCTCCTTGGACCCTCAAGCATAGCTGGTAAATCAAGTTAGAGATGTAACTGCCTTAAAACATGCCAGCTTAggctgggcacggtggctcacacctgtaatctcaacacttcaggaggctgaggcaggcagatcacttgaggtcaggagttcgagaccagcctgaccaacatggagaaattctgtccctactgaaaatacaaaattagccggatgtggtggtgcatgcctgtaatcccagctacttgggaggctgaggcaagagaattgcttgaacccagggaggcagaggttgcagtgagccgagatcacaccattgcactccaccttgggcaacaaaagcaaaactctgtctcaaaaaaaaaaaaaaaaaaaGTGCCAGCGTATGAGGTAATTAGATTGGTTCTCTCCAGAGGTAACCTGCCAAGAAGAGATGCTATAGATGTTACTCCTATACTGTAAAACATTGTGAAATCAGATTACTTTAAAATGATGTATTACAAAGTTATGCAAAAAAGCAGTTGTGACTATGGAAGCCCAAGGCTTATATCCCAGCTCTGTCTTACACTAAATATGGGTACAGTgtttccactctgtccataaaatgggagctaatattctccaacctgtgtgcctgacatgatggttaaagggattaaacaaaacaatagtttgtaatttattctgtcagagcaaactgctggtaaataaaagggactaAGTTGACGAAAAATAAATTTTAAAAAACCTAATAAAACAAGTTTGTAATTTATAATTGTATACAAATAAAAGATGTTACAAAAATTGCGCACTTA

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