Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TVP23CP2
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:14200286-14202120  UCSC
Coordinates (T2T) chr16:14237554-14239388  UCSC
Coordinates (hg19) chr16:14294143-14295977  UCSC
Strand +
Parental Sequence NM_016078.6
Parental seq. overlap 1770 bp
Parental seq. overlap (%) 94%
Genomic Region Intragenic (MRTFB)
Retrocopy Summary TVP23CP2, located on chr16:14200286-14202120, is a retrocopy of the parental gene TVP23B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TVP23B
Full Name trans-golgi network vesicle protein 23 homolog B
Also known as CGI-148|FAM18B|FAM18B1|NPD008|YDR084C
Coordinate chr17:18781183-18806714
Strand +
Gene summary Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be integral component of membrane. Predicted to be integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TVP23BP7
Bonobo Pan paniscus CDRT4P7
Gorilla Gorilla gorilla TVP23BP3
Gibbon Nomascus leucogenys LOC101176802P5
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TVP23CP2
GAGTTCCGACCCGGACCCGTACGCTGCTGCGCTGACGTGGCTCCCGGAAGTAAGGCTGGCGTAGGGCCGCCATGTTGCAGCAGGATAGTAATGATGACACTAAAGATGTTTCACTGTTTGATGCGGAAGAGGAGACGACTAATAGACCAAGAAAAGTCAAAATCAGACATCCAGTAGCATCGTTTTTCCACTTATTCTTTCGAGTCAGTGCAATCATCGTCTGTCTTCTCTGTGAATTGCTCAGCAGCAGCTTTATTACCTGTATGGTAACAATTATCTTGTTGTCATGTGACTTTTGGGCAGTGAAGAATATCACAGGTAGACTAATGGTTGGCCTACGTTGGTGGAATCACGTTGATGAAGATGGAAAGAGCCACTGGGTGTTTGAATCTAGAAAGGAGTCCTCTCAAGAGAATGAAACTGTGTCAGAGGCTGAATCAGGAATCTTTTGGTTGGGACTTGTTGCCTGTCCAGTGCTGTGGGTGATACTTGCCTTCAGTGCACGCTTCTCCTTCAGAGTAAAAAGTGGTTGGCGGTGGTTATCGTGGGTGTGGTGCTACAAGGTGCCAACCTGTATGGTTACCTCAGGTGTAAGGTGGGCAGCAGAAAGAATTTAACCAGCATGGCTACTTTATATTTTGGAAAGCAGTTTTTAAGACAAAACACTGGAGATGATCAGACTTCCTGAAGAGAGAAAGCTTATGTGCTTTGTTACATTGGGGAACAACTGAAGAGATAAGTCTTGACTTTGAACCTTTTAGAGCTTAGTCCATGTTGCAACGAGGAGTGTTGGCTTTGTTTTTCCACTTAAAAACTTTATTTATAAAAAGGAAAAATAGTTTTCGTATTAAGTTTTTATTTCCAGCAGTTGGGGCGAGAAAGTATATGTTGGCACTAGAAACATTGTCAAGATTTATTCTGTGGTGTAGGTATGCACATTCCATAGGTATGCACACGGCCATGTAATATCAGTATATCCCAAGTTAACGAAAGTGTTCATTTACATAGGCAATGGAGACCTTTGCATTGTGATCCATAGAACATAGGAGGATGTTCTTAGTGTGTCTCAAAGCTCTATATGTTTACATATTATTTCTGTAGATTGTTTTCAGGAGAAAGTTTTGCTTCCATGGTAAGAGTGAGCACTTTGGCTTCTGTGTAAGTTAGAAATAATTGTTAGTTTTTAATATGTACTTCCTGGGGAAATTTCTTAGATGTTTGCAAGCAAGTGAAAACAGTTAGGGCCAGTGGTACTAACTACTTTATAAAATTTTATTTTTATTTGTAAGAAGTCATCTACTTAAGGCCCAGTTAATATAAGTGGAATCATCGTAGTTTAAGGAATACCCAGAGATTGCTGCTGTTCTATTTATTTTACAGAAAGGATAGCTAGATTGAAAGCTCTTCAGTGGACCTTGAGCTAATAGAGCTTTTACCACTAAAAGAGCATTATTCTCATGTCATAATGAGAATAATCATTTACATACTTGGCATAATAAATGCCTAAAAGACATTTTATTTTCTGAATCTATCGTTTTCTTGCTATAATGGGGATATTGTAAATTATGCATTTGTATTAATGGTATTTCTTAAAGCAATCTATGTAACTGTAAACTAAACCAATCTACAAACTATTGTAGGCATCTGTAAATTCTGTCGTAGGTATTATAAACCTTGTTGAAGTCTTAATCAGCAGATTATGTTGTGAATGTATTTGTACATTGTTAAAATAGTTTTTAAGATTATTTGTTTAATTGAATAAGTGTCTTATTAGAGTGATAGCTTTGAAGGTGCAAAACTTTATATTTGTATAAAATTCTACTGTTTACAAGGCA
>NM_016078.6
CTTACAGTGGTCCCTGCTGGCCCTTGGTGACGGGTCGCCTCAGTTCCGACCCGGACCCGTACGCTGCTGCGCTGACGTGGCTCCCGGAAGTAGGGCTGGCGTAGGGCCGCCATGTTGCAGCAGGATAGTAATGATGACACTGAAGATGTTTCACTGTTTGATGCGGAAGAGGAGACGACTAATAGACCAAGAAAAGCCAAAATCAGACATCCAGTAGCATCGTTTTTCCACTTATTCTTTCGAGTCAGTGCAATCATCGTCTATCTTCTCTGTGGGTTGCTCAGCAGCAGCTTTATTACCTGTATGGTGACAATTATCTTGTTGTTGTCGTGTGACTTTTGGGCAGTGAAGAATGTCACAGGTAGACTAATGGTTGGCCTACGTTGGTGGAATCACATTGATGAAGATGGAAAGAGCCATTGGGTGTTTGAATCTAGAAAGGAGTCCTCTCAAGAGAATAAAACTGTGTCAGAGGCTGAATCAAGAATCTTTTGGTTGGGACTTATTGCCTGTCCAGTACTGTGGGTGATATTTGCTTTTAGTGCACTCTTCTCCTTCAGAGTAAAGTGGTTGGCGGTGGTTATCATGGGTGTGGTGCTACAAGGTGCCAACCTGTATGGTTACATCAGGTGTAAGGTGCGCAGCAGAAAGCATTTAACCAGCATGGCTACTTCATATTTTGGAAAGCAGTTTTTAAGACAAAACACTGGAGATGATCAGACTTCCTGAATAGAGAAAGCTTATGTGCTTTGTTACATTGGGGAACAACTGAAGAGATTCTTGACTCAACCTTTTAGAGCTTAGTCCATGTTGCAACGAGGAGTGTTGGCTTTGTTTTTCCACTTAAAAACTTTATTTATAAAAAGGAAAAGTAGTTTTCATATTAAGTTTTTATTTCCTTTCCAGCAGTTGGGGCTAGAAAGTATGTGTTGGCACTAGAAACATTGTCAAGATTTGTTCTGTGGTGTAGGTATGCACATTCCATAGGTATGCACACGGCCATGTAATATCAGTATATCCCAAGTTAATGAAAGTGTTCATTTACATAGGTAATGGAGACCTTTGCATTTTGATCCATAGAACATAGGAGGATGTTCTTAGTCTGTCTCAAAGCTCTATATGTTTACATATTATTTCTGTAGATTGTTTTCAGGAGAAAGTTTTGCTTCTATGGTAAGAGTGAGCACTTTGGCTTATGTATAAGTTAGAAATAATTGTTAGTTTTTAATATGCACTTCGTGGGGAAATTTCTTAGACGTATGCAAGCAAGTGAAAACAATTAGGGCCAGTGGTATTAACTACTTTATAAAATTTTATTTTTGTTTGTAAGAAGTCATCTATTTAAGGCCCAGTTAATATAAGTGGAATCATCATAGTTTAAGGAATACCCAGAGATTGCTGCTGTTCTATTTATTTTACAGAAAGGATAGCTAGATTGAAAGCTCTTCAGTGGACCTTGAGCTAATAGATCTTTTACCACTAAAAGAGCATTATTCTCATGTCATAATGAGAATAATAATTTACATACTTGGCATAATAAATGCCTAAAAGACATTTTATTTTCTGAATCTATTTTTTTCTTGCTATAATGGGGATATTGTAAATTATGCATTTGTATTAATGGTATTTCTTAAAGCAATCTATGTAACTGTAAATTAAACCAATCTACAAACTATTGTAGGCATCTGTAAATTCTGTTGTAGGTATTATAAACTTTGTTGAAGTCTTAATCAGCAGATTATGTTGTGAATATATTTGTACATTGTTAAAATAGTTTTTAAGATTATTTGTTTAATTGAATAAGTGTCTTATTGGAGTGATAGCTTTGAAGGTGCAAAActttatatttgtataaaattctactatttacaaggca

Publications

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