Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MOCS1P1
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:48496656-48499423  UCSC
Coordinates (T2T) chr16:54294333-54297100  UCSC
Coordinates (hg19) chr16:48530567-48533334  UCSC
Strand +
Parental Sequence NM_001075098.4
Parental seq. overlap 2526 bp
Parental seq. overlap (%) 60.4%
Genomic Region Intergenic
Retrocopy Summary MOCS1P1, located on chr16:48496656-48499423, is a retrocopy of the parental gene MOCS1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MOCS1
Full Name molybdenum cofactor synthesis 1
Also known as MIG11|MOCOD|MOCS1A|MOCS1B
Coordinate chr6:39904170-39934462
Strand -
Gene summary Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16. [provided by RefSeq, Nov 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MOCS1P1
Bonobo Pan paniscus MOCS1P1
Gorilla Gorilla gorilla MOCS1P1
Orangutan Pongo abelii MOCS1P1
Gibbon Nomascus leucogenys MOCS1P1
Green monkey Chlorocebus sabaeus MOCS1P1
Crab-eating macaque Macaca fascicularis MOCS1P1
Rhesus Macaca mulatta MOCS1P1
Baboon Papio anubis MOCS1P1
Golden snub-nosed monkey Rhinopithecus roxellana MOCS1P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MOCS1P1
GATCAGGCTTCACGGTGGCGCGGCCGCTGTCCCGGATGCTGCGCCGGCTCCTAAGGTCCAACGCCACGGAGCTGCAGCTCACGGGTTCCGGTGATGCCGCCCCGCCCGGGCGAGTCCCCGCAAGCTGCCTCACAGGAGCTGTCCAGGTGGAGGCAGTTCTCGCGGGAGCACGAGGCCCCCTTCTCCGCCTTCCTCACAGACAGCTTCGGCGGGCAGCACAGCTACCTGCGGATCTCCCTCCCGGAGAAGTGCAACCTCAGATGTCAGTACTGCATGCCGGAGGAAGGGGTCCCGCTGACCCCCAAGGCCAACCTGCTGACCACAGAAGAGATGTTGACCACAAAAGAGATCCTGACCCTCGCCTGGCTTTTTGTGAAGGAAGGCGTCGAAAAGATCTGGCTCATGGGCGGAGAGCCGCTCATCCAGCCGGACGAGGTGGACATTGTGGCCCAGCTCCAGCGACTGGAAGGGCTGAGGACCATTGGTGTCACCACCAATGGCATCAACCTGGCCCGGCTGCTGCCCCAGCTTCAGAGGGCTGGTCTCAGCGCCATCAACATCAGCCTGGACACACTGGTGCCTGCCAAGTTTGAGTTCATTGTCCGCAGGAAAGGCTTCCACAAGGTCATGGAGGGCATCCACAAGGCCAATGAGCCAGGCTACAACCCTGTGAAGGTGAACTGTGTGGTGACGCGAGGCCTTAACGAGGATGAACTCCTGGACTTTGCGGCCTTGATCAAGGGCCTCCCCCTGGACGTGGCCTTCATAGAGTACATGCCCTTTGATGGCAACAAGTGGAACTTCAAGAAGATGGTCGCTATAAGGAGATGCTAGAAACTGTATGGCAGCTGTGGCCAGAGTTGGAGAAGCTGTCAGAGCAGGAATCCAGGACAGCCAAGGCCTTTAAAATCCCTGGCTTCCAAGGCCAGATCAGCTTCATCATGTCCATGTCTGAGCATTTCTGTGGGACCTGCAACCACCTGCAAATCACAGCTGACGGGAACCTCAAGGTCTGCCTCTTTGGAAACTCTGAGGTATCTCTACGGGATCACTGTGATCTGGGGCCTCCAAGCAGGAGCTGCTGAGAATCATTGGCGCTGCCGTGGGCAGGAAGAAGCAGCAGCATGCAGGCATGTTCAGTATTTCCCAGATGAAGAACTGGCCCATGATCCTCATCGGTGGGTGACCCCCATCAAGACATTTTTGATGTTCCACGATTCCCCACCAGCCAATCCAAGCATTTCCTCCTGGGACCCCCTCCATGTTCAAGGTCTGAGATCCAGAATGAATTTCTCCAGTCAGATGGCCACTTTATGGAAAGGATACAGGGTACCCCAGACCCCTCTTCTAGCCCAGCAGCAGCTAGGTTCTGGCTCCTTTCAGAGACACTACACTTCCCATGCAGACTCAGATGCCAACTCAAAGTGCCTTAGCCCAGGTTCCTGGGCTCCTGCTGCCCCCTCAGGACACCAGCTAAACTCAGAACAACTAACTCATGTGGATTTGGAAGGACGGGAAGCTATGGTAGATGTGGGCAGGAAGCCAGACACAGAGTGGTTGGCTGTGGCCTCAGCCATGGTCATCCTGGGGCCTGTAGCCTTCAAGCTTGTCCAGCAGAACCAGCTCAAGAAAGGAGATGCCCTGGTGGTGGCCCAGCTGGCTGGAGTCCGGGCAGCCAAGGTGACCAGCCAGCTGATCCCTCTGTGCCACCACGTGGCCCTGAGCCACGTCCAGGTGCAGCTGGAGCTGGACAGCACATGCCATGCTGTGGAGATCTGGGCATCTTGCCAGGCTCGGGGCCCCCACCAGGGTGGAAATGGAGGCCCTGACCTCTGCTGCAGTGGCCGCCCTCACCCTGTGTGACATGTGCAAGGCTATCAGCAGGGACATCGTGTTGGAGGAGATCAAGCTCATTAGCAAGACTGGAGTTCAGTGGGGGGACTTCCATTGGGTTTAGCTTCTGCCCTTCTCACCCATGGCCCAGCCAGGTCTGAAGATGGGGTGCAATTTAAGCTGAGGGAAAGACATCAAGTTCCTTTCATCACAGTCACTGTTTACCTTGAGCAGTAAACCTGAAGTCAGCCTGCTCTACTACTAGGCCTGCTGCTAGATGATCTTTAATGACCAATGGGGCTTCCTTTCTATAGGGAGGATACCAGGAGGCCCTTAAGCCTTCCAGGACACTAAGTTCATGGGAGCCAGACTGCAACAAGCAATGCTAGATAACTGAGAAATCATGTTCTTTCTGGACTATTTCAGACAAACAGTCTCAGACAGTCCAGCCCAGAAATGTTCCTTCTCATTTTGGGTTTTCTCTTCTCCTACTTTCCTGGGGAGAGATTAAGGGCTCATTAAGCGGAGGAACCCACTTTGAGGAGAGTAAAGCCCAAGCTTGCCTGAAGAATGCATCTCCCCAGCAGCTCTGCCTCCCTAAGTCTGTGAAGCCACAGCCCTGCCCTGTCCTGACTTTATCTCCCTTCTGCCCAAGTCTATGTCCCATCAAACTTGCAGCTTTTCAGCTTAACAGTTGCCTGGTCCTGCTGGCCCCCTTTTCTCAGGCCCCCCTCCTCTGAAACGGGATGTGAACACGTGGGCCACAGCCCTAAGGACTCCTGACAGACCACATAGCCCACAACTGGCCCTGCTCATGGCTGTTCCACCCACCCCTCTTTATTCTGGAGCATATCAGGGAAAGAAGAGTTGACGATAGATTGCCTTCACCCTCACAGTGCACAAATAAAGC
>NM_001075098.4
AGTGTGCTCCCGAAGCGGGCTGCGGTTCCGCTCGTATCAGGCTTCATGGCGGCGCGGCCACTGTCCCGGATGCTGCGGCGGCTTCTGAGGTCCAGCGCCCGGAGCTGCAGCTCAGGGGCTCCGGTGACCCAGCCCTGCCCCGGGGAGTCCGCGCGAGCTGCCTCGGAGGAGGTGTCCAGGCGGAGGCAGTTCCTGCGGGAGCATGCGGCCCCCTTCTCCGCCTTCCTCACAGACAGCTTCGGCCGGCAGCACAGCTACCTGCGGATCTCCCTCACAGAGAAGTGCAACCTCAGATGTCAGTACTGCATGCCCGAGGAGGGGGTCCCGCTGACCCCCAAAGCCAACCTGCTGACCACAGAGGAGATCCTGACCCTCGCCCGGCTCTTTGTGAAGGAAGGCATCGACAAGATCCGGCTCACAGGTGGAGAGCCGCTTATCCGGCCGGACGTGGTGGACATTGTGGCCCAGCTCCAGCGGCTGGAAGGGCTGAGAACCATAGGTGTTACCACCAATGGCATCAACCTGGCCCGGCTACTGCCCCAGCTTCAGAAGGCTGGTCTCAGTGCCATCAACATCAGCCTGGACACCCTGGTGCCTGCCAAGTTTGAGTTCATTGTCCGCAGGAAAGGCTTCCACAAGGTCATGGAGGGCATCCACAAGGCCATCGAGCTGGGCTACAACCCTGTGAAGGTGAACTGTGTGGTGATGCGAGGCCTTAACGAGGATGAACTCCTGGACTTTGCGGCCTTGACTGAGGGCCTCCCCCTGGATGTGCGCTTCATAGAGTATATGCCCTTTGATGGCAACAAGTGGAACTTCAAGAAGATGGTCAGCTATAAGGAGATGCTAGACACTGTCCGGCAGCAGTGGCCAGAGCTGGAGAAGGTGCCAGAGGAGGAATCCAGCACAGCCAAGGCCTTTAAAATCCCTGGCTTCCAAGGCCAGATCAGCTTCATCACATCCATGTCTGAGCATTTCTGTGGGACCTGCAACCGCCTGCGAATCACAGCTGATGGGAACCTCAAGGTCTGCCTCTTTGGAAACTCTGAGGTATCCCTGCGGGATCACCTGCGAGCTGGGGCCTCTGAGCAGGAGCTGCTGAGAATCATTGGGGCTGCTGTGGGCAGGAAGAAGCGGCAGCATGCAGGCATGTTCAGTATTTCCCAGATGAAGAACCGGCCCATGATCCTCATCGGTGGGTGACCCATCAAGTTATTTTTGATGTTCCCCAATTCCCCACCAGCCAATCCAAGCATTTTCTCCTGGGACCCGCTCCATGTTCAGGGTCTAAGACCCAGAATGAGTTTCTCCAGCCAGGTGGCCACTTTATGGAAAGGATGCAGGGTCCCCCAGACCCCTCCTCTAGCCCAGCAGCGGCTGGGGTCTGGCTCCTTTCAGAGACACTACACTTCCCGTGCAGACTCAGATGCCAACTCAAAGTGCCTTAGCCCAGGTTCCTGGGCTTCTGCTGCCCCCTCAGGACCCCAGCTAACCTCAGAACAACTAACTCATGTGGACTCGGAAGGACGGGCAGCTATGGTAGATGTGGGCAGGAAGCCAGACACAGAGCGGGTGGCTGTGGCTTCAGCCGTGGTCCTCCTGGGACCGGTAGCCTTCAAGCTTGTCCAGCAGAACCAGCTCAAGAAAGGAGATGCCCTAGTGGTGGCCCAGCTGGCTGGAGTCCAGGCAGCCAAGGTGACCAGCCAGCTGATCCCTCTGTGCCACCACGTGGCCCTGAGCCACATCCAGGTGCAGCTGGAGCTGGACAGCACACGCCATGCCGTGAAGATCCAGGCATCTTGCCGGGCTCGGGGCCCCACCGGGGTGGAGATGGAGGCCCTGACCTCTGCTGCAGTGGCCGCCCTCACCCTGTATGACATGTGCAAGGCTGTCAGCAGGGACATCGTGTTGGAGGAGATCAAGCTCATTAGCAAGACTGGTGGTCAGCGGGGGGACTTCCATCGGGCTTAGCACCTGCCCTTCTCACCCATGGCCCACCCAGGCCTGGAGCTGGGATGCAATGTAGGCTGAGGGAAAGACGTCAGGTTCCTTTAATCACAGTCACTGTTTGTTTACCTTGAGCAGTAAACCCGAAGTCAGCCTGCTCTACTACTAACAAACAGGCCTGCTGCTAGATGATCTCTAATGACCAATGGGGCTTCCTTTCTATAGGGAGGATACCAGCAGGCCCTTAAGCCTTCCAGGACACTAAGGTCGTGGGAGCGGGACTGCAACAAGCAATGCCAGATAACTGAGAAATCATGTTCTTTGTGGACTATTTCAGACAACCAGGTTCCGACAGTCCAGCCCAGAACTTTTCCTTCTCATTTTGGGTTTTCTCTTCTCCTGCTTTCCTGGGGAGAGATTAAGCGCTCATTAAGCAGAGGAGCCCACTTTGAGGAGAGCAAAGCACAAGCTTGCCTGAAGAATGGATCCCAACTTCTCCCCGGCAGCTCTGCCTCCCTAAGTCTGTGAAGCCGCAGCCCTGCCCTGTCCTGTCCTGTCCTGACTTCATCTCTCCTTCTGCCCAAGTCTGTGTCCCATCAGACTTGCAGCCTTTCAGCTTAACAGTTGCCCGGTCCTGCTGGCCCCTTTTCCTCTGGCCCCCCTCTTCTGAAACAGGATGTGCACACATGGGCCATAGCCCTAAGGACTCCTGCCAGACCACACAGCCCACACCTGGCCCTGTTCACGGCTGTTCCACCCACCCCTCTTTATTCTGGAGCATATCAGGGAAAGAAAAGTTGATGATAGATTGCCTTCACCCTCACAGCGCACAAATAAAGCTACGATGCCAACTTTGCAGATGCAAGAATGAAGACACTGTGTGGGTAGGGCACTGAGCTGCTGCAGTTTCACAGGGAAGGCTGCACCTATCAATCAATCAATCAATCCTATCCCAAGACACAGTTCCCTGAGGGAAGAAGAGGAGGGACCTGGAAAGGCCTAAGGGTGTACTCTCTGTATAGCCCCGCTATGGGAAAATAAAGTGGAGTAGGGGGCATAGAAATGCACCATCTAAGGGAAATCTTTTGTCAGGTGGTGGCCAGGGGTGTTCAAAGCTCATTGCTTGCATTACCAGCTATTAGAGAGATCAGAGAGGGCAATTAATTAGAGGCTCCTGGTTCTCACATCCCAAACACACACAGTTCTGGCCTGCTGGGCTCTCTAACTTGGATGTCTTTGAGTCCTCAGTGGTGCCCCCTGCCTGCCTCCCCTCTGCCCTATGCCAAggtgtgctggcaaatattaaacaaccagctctctggaaaagacaatttgtgatataaatactcccatgttgaataatttcaagctaccagtatgtcaaatggcttgcaaaatttctgaaaatgtaaacaattggttctcacagagctggtacaagctggctccagcacacTCTCAGCCCACCCCAGATCCCCTCATAGGAAGAAGGCACAAGTTTAAAGGCAGACTGGGTAGGGATGGTATGAATTTAATATTTTTTAGTATTACAATATATTCTTATAAAAAAGGTGCAAGTGAAAAAGGACACTGTAGATTATGTCCATTAGCCTCATTTGTCATCTGAGGCAGCTGGTGAGAACAGCCTTGGCGTGAAGGCATCCCTGGTAGAAGTCGGGGGAGATAGATAGTCACAGTTCCCCAGTTGGTGGAAATGGGATGGGAGTAGGGAGAGGCTGGAACAGACCCTTCCCCATTCACCTGGAGAATTTTCTCCTCCCACTGCCCTAAACACTTTATTTCCATCACAGGGGAGAAATGCTGCTGAGAAGGTTGTGTTTGTTAGGTTGATGACGAATTTTACATTGGCCACAAAATTAGCTAGAGAAACTTATCTAAAGGTGGCAGGAGCAGTGGGGAGGGCATGAAGAAAGCAAGACCAAGAAACAACCTATTAAGGACCAGCTCAGCCACCCCGACTGGGCACCAGCCCCTTCTTACTCAGTTGAGTATGAGTCCATGGTCCAAGGCACTGTTGGAGATCTGGCTACAGTGGCATCTAGCACCAGAGCCACTGGCCAGATGTAGAAAATAAATAGAAAAATATCTTTCTTTTAGAGTGAGAAGGCTGAGCTCTGGAACAACGTATTTGTGTCCTCTGTCAACAGTTGAACCAAATTCTGCTTTTCTGAAGATCAAATGTATCTTGAA

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