Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NOP58P2
Plot displaying the genomic locations of a retrocopy (in chr16) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr16:60024357-60024905  UCSC
Coordinates (T2T) chr16:65816191-65816740  UCSC
Coordinates (hg19) chr16:60058261-60058809  UCSC
Strand -
Parental Sequence NM_015934.5
Parental seq. overlap 227 bp
Parental seq. overlap (%) 10.3%
Genomic Region Intergenic
Retrocopy Summary NOP58P2, located on chr16:60024357-60024905, is a retrocopy of the parental gene NOP58. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NOP58
Full Name NOP58 ribonucleoprotein
Also known as HSPC120|NOP5|NOP5/NOP58
Coordinate chr2:202265763-202303661
Strand +
Gene summary The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs. [provided by RefSeq, Nov 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NOP58P2
Bonobo Pan paniscus NOP58P2
Gorilla Gorilla gorilla NOP58P2
Orangutan Pongo abelii NOP58P1
Gibbon Nomascus leucogenys NOP58P1
Green monkey Chlorocebus sabaeus NOP58P1
Crab-eating macaque Macaca fascicularis NOP58P1
Rhesus Macaca mulatta NOP58P1
Baboon Papio anubis NOP58P1
Golden snub-nosed monkey Rhinopithecus roxellana NOP58P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NOP58P2
GAGAGATCACAAGAACTAACAGAAAGGAATTACGATTATATCACCTGGACGCATCATGCTTAAGATTCAACTGGGAGCGTACCAGGGATGCTCTCTAACCTAATCAAGGGAAGGTTCATTAAAACAAAGTGATTTATCATCTATAACGTCAAACCTATTTGTGTCTTGACATCAACTCTGTTAACTTATGTCATCATTTCTTAGAGTCTTTAATGTACAAATAAAATTTTCTTTGTATTAACACATTAAGGAAGAACCACTTTCTGAGGAAGAACCATGTACCAGCACAACAATTCCTAGTCCAGAGTGAAATGAAGACTTATGATTCTTCTGGTGACTCCACACCTCCAACCTGTTCTAAAAAATGCAAAATAGAACAGGTAGATAAAGAGGATGAAATTACTGAAAAGAATGCAAAAAAAAAAAGCCAAGATTAAAGTTAAAGCTg
>NM_015934.5
CTAGTTCCAGTACAGCGTGGAGGGTTTAGGCAGCGTGTTCTGATTCTTTGCGGGACGGCGAGCGCATTTGTGCTTTGCCCGCCGCGGCCTAGGAGGCCTTTTGAGGCCGCGTAGTCGGTGTTTTTGAACTGACTCTACAGCTTCTGGCAGGCCGTGCGGCGCCCTGACCCGGCCTCACCATGTTGGTGCTGTTTGAAACGTCTGTGGGTTACGCCATCTTTAAGGTTCTAAATGAGAAGAAACTTCAAGAGGTTGATAGTTTATGGAAAGAATTTGAAACTCCAGAGAAAGCAAACAAAATAGTAAAGCTAAAACATTTTGAGAAATTTCAGGATACAGCAGAAGCATTAGCAGCATTCACAGCTCTGATGGAGGGCAAAATCAATAAGCAGCTGAAAAAAGTTCTGAAGAAAATAGTAAAAGAAGCCCATGAACCGCTGGCAGTAGCTGATGCTAAACTAGGAGGGGTCATAAAGGAAAAGCTGAATCTCAGTTGTATCCATAGTCCTGTTGTTAATGAACTTATGAGAGGAATTCGTTCACAAATGGATGGATTAATCCCTGGGGTAGAACCACGTGAAATGGCAGCTATGTGTCTTGGATTGGCTCACAGCCTGTCTCGATATAGATTGAAGTTTAGCGCTGATAAAGTAGACACAATGATTGTTCAGGCAATTTCCTTGTTAGATGACTTGGATAAAGAACTAAACAACTACATTATGCGATGTAGAGAATGGTATGGCTGGCATTTCCCTGAATTAGGAAAAATTATTTCAGATAATTTAACATACTGCAAGTGTTTACAGAAAGTTGGCGATAGGAAGAACTATGCCTCTGCCAAGCTTTCTGAGTTGCTGCCAGAAGAAGTTGAAGCAGAAGTGAAAGCAGCTGCAGAGATATCAATGGGAACAGAGGTTTCAGAAGAAGATATTTGCAATATTCTGCATCTTTGCACCCAGGTGATTGAAATCTCTGAATATCGAACCCAGCTCTATGAATATCTACAAAATCGAATGATGGCCATTGCACCCAATGTTACAGTCATGGTTGGGGAATTAGTTGGAGCACGGCTTATTGCTCATGCAGGTTCTCTTTTAAATTTGGCCAAGCATGCAGCTTCTACCGTTCAGATTCTTGGAGCTGAAAAGGCACTTTTCAGAGCCCTCAAATCTAGACGGGATACCCCTAAGTATGGTCTCATTTATCATGCTTCACTCGTGGGCCAGACAAGTCCCAAACACAAAGGAAAGATTTCTCGAATGCTGGCAGCCAAAACCGTTTTGGCTATCCGTTATGATGCTTTTGGTGAGGATTCAAGTTCTGCAATGGGAGTTGAGAACAGAGCCAAATTAGAGGCCAGGTTGAGAACTTTGGAAGACAGAGGGATAAGAAAAATAAGTGGAACAGGAAAAGCATTAGCAAAAACAGAAAAATATGAACACAAAAGTGAAGTGAAGACTTACGATCCTTCTGGTGACTCCACACTTCCAACCTGTTCTAAAAAACGCAAAATAGAACAGGTAGATAAAGAGGATGAAATTACTGAAAAGAAAGCCAAAAAAGCCAAGATTAAAGTTAAAGTTgaagaagaggaagaagaaaaagtggcagaagaagaagaaacatctgtgaagaagaagaagaaaaggggtaaaaagaaACACATTAAGGAAGAACCACTTTCTGAGGAAGAACCATGTACCAGCACAGCAATTGCTAGTCCagagaaaaagaagaaaaagaaaaaaaagagagagaacgaggattaacagaaaggaaTTACGATTATATCACCCGGACACACATCATGCTTAAGATTCAACTGGGAGCATACCAGGGATGCTCTCTAACGTAATCAAGGGAAGGTTCAGTAAGACAAAGTGATTTATCATCTATAACTTCAAACCTATTTGTCTTGACATCAACTCTGTTAACCTTATGTCATCATTTCTTAGAGTCTTTGATATACAAATAAAATTTTCTTTGTATTTTAA

Publications

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