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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name TXNP2
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:68514355-68514734  UCSC
Coordinates (T2T) chr1:68391751-68392130  UCSC
Coordinates (hg19) chr1:68980038-68980417  UCSC
Strand -
Parental Sequence NM_003329.4
Parental seq. overlap 308 bp
Parental seq. overlap (%) 41.8%
Genomic Region Intergenic
Retrocopy Summary TXNP2, located on chr1:68514355-68514734, is a retrocopy of the parental gene TXN. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TXN
Full Name thioredoxin
Also known as TRDX|TRX|TRX1|Trx80
Coordinate chr9:110243810-110256507
Strand -
Gene summary The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TXNP2
Bonobo Pan paniscus TXNP2
Gorilla Gorilla gorilla TXNP2
Orangutan Pongo abelii TXNP2
Green monkey Chlorocebus sabaeus TXNP11
Crab-eating macaque Macaca fascicularis TXNP2
Rhesus Macaca mulatta TXNP2
Baboon Papio anubis TXNP2
Golden snub-nosed monkey Rhinopithecus roxellana TXNP7
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TXNP2
TGGTGCTTTGGATTCATTTCTATCTATTCTTACAGTTGCTAGTCAGACCTCAACAGTCAAAATGGTGAAGCATATTGAGAACAAGTATGCTTTTCAGGAGGCCTTGGACAATCTAGGAGACAAACCTATAGTAGTTGATTTCTCAGCCACGTGTTGCAAGCTTTACAAAATAATCGAGCCTTTCATTCCCTCTCTGCAAAGCATTCCAAGATGGTGTTGCTTGGAGTAGACATGGAAGACTGTCAGGAAGTTGCTTCAGAGTGTGAAGTTAAATGCATGCCAATTTTTGAGTTTTTTTTAAAGGACAAAAGGTGTGTAAATTTTCTAATAAGAAAAAGCTTGAAGTCACTATTAATAAATTAACCTAGTTATGt
>NM_003329.4
GAAGCTCTGTTTGGTGCTTTGGATCCATTTCCATCGGTCCTTACAGCCGCTCGTCAGACTCCAGCAGCCAAGATGGTGAAGCAGATCGAGAGCAAGACTGCTTTTCAGGAAGCCTTGGACGCTGCAGGTGATAAACTTGTAGTAGTTGACTTCTCAGCCACGTGGTGTGGGCCTTGCAAAATGATCAAGCCTTTCTTTCATTCCCTCTCTGAAAAGTATTCCAACGTGATATTCCTTGAAGTAGATGTGGATGACTGTCAGGATGTTGCTTCAGAGTGTGAAGTCAAATGCATGCCAACATTCCAGTTTTTTAAGAAGGGACAAAAGGTGGGTGAATTTTCTGGAGCCAATAAGGAAAAGCTTGAAGCCACCATTAATGAATTAGTCTAATCATGTTTTCTGAAAATATAACCAGCCATTGGCTATTTAAAACTTGTAATTTTTTTAATTTACAAAAATATAAAATATGAAGACATAAACCCAGTTGCCATCTGCGTGACAATAAAACATTAATGCTAACACTTTTTAAAACCGTCTCATGTCTGAATAGCTTTCAAAATAAATGTGAAATGGTCATTTAATGTATTTTCCTATATTCTCAATCACTTTTTAGTAACCTTGTAGGCCACTGATTATTTTAAGATTTTAAAAATTATTATTGCTACCTTAATGTATTGCTACAAAAATCTCTTGTTGGGGGCAATGCAGGTAATAAAGTAGTATGTTGTTATTTGTTA

Publications

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