Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name MAGOH2P
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:10716034-10716582  UCSC
Coordinates (T2T) chr17:10623585-10624133  UCSC
Coordinates (hg19) chr17:10619351-10619899  UCSC
Strand -
Parental Sequence NM_002370.4
Parental seq. overlap 509 bp
Parental seq. overlap (%) 77.5%
Genomic Region Intragenic (TMEM220)
Retrocopy Summary MAGOH2P, located on chr17:10716034-10716582, is a retrocopy of the parental gene MAGOH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MAGOH
Full Name mago homolog, exon junction complex subunit
Also known as MAGOH1|MAGOHA
Coordinate chr1:53226900-53238518
Strand -
Gene summary Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MAGOHP1
Bonobo Pan paniscus MAGOHP2
Gorilla Gorilla gorilla MAGOHP1
Orangutan Pongo abelii MAGOHP2
Gibbon Nomascus leucogenys MAGOHP2
Green monkey Chlorocebus sabaeus MAGOHP2
Crab-eating macaque Macaca fascicularis MAGOHP2
Rhesus Macaca mulatta MAGOHP2
Baboon Papio anubis MAGOHP2
Golden snub-nosed monkey Rhinopithecus roxellana MAGOHP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MAGOH2P
AGTGTTGGGTGCAGACCGCGGTGGTGCAGCTTTCTTTTAGAAGTTCAGTCTCAGTTGTCTTTTGCAAGCCATGAAGAGTGACTTTTATCTGCGCTACTACGTGGGGCACAAGGGCAAGTTCAGCCACGAGTTTCTGGAGTTTGAGTTCTGACCGGACGGGAAATTAAGATAAGCCAACACAGCAATTACAAGAATGATGTCATGATCAGAAAAGAGGCTTATGTACATAAAAGTATGATGGAGGAACTGAAGAGTATAATTGATGACAGTGAAATTACCAAAGAGGATGATGCGTTATGGCCTCCTCCCAACCGAGAGGGCCGGCAGGAGCTTGAAATCATTATTGGAGATGAACACATTTCTTTTACAACATCAAAAATTGGTTCCCTTATTGATGTCAGTCAATCCAAGGATCCAGAAGGCTTATGAGTATTTTATTATCCTGTCCAGGACCCTGAAGTGTTTGGTCTTCAGTCTTACTGGATTACACTTCAAGATTAAACCAATCTAAACTGAATATTGATGTGGACATGGGGGGGTGGGAGTAGT
>NM_002370.4
AGTGTCGGGCGCAGACGGCGGCAGTGCGGCTTGCTCTTGGAAGTTCAGGCTCGGTTGTCTTTTGGGAGCCATGGAGAGTGACTTTTATCTGCGTTACTACGTGGGGCACAAGGGCAAGTTCGGCCACGAGTTCCTGGAGTTTGAGTTTCGACCGGACGGGAAGTTAAGATATGCCAACAACAGCAATTACAAGAATGATGTCATGATCAGAAAAGAGGCTTATGTACATAAAAGCGTGATGGAGGAACTGAAGAGAATAATTGACGACAGTGAAATTACCAAAGAGGATGATGCATTGTGGCCTCCTCCTGACCGAGTGGGCCGGCAGGAGCTTGAAATCGTCATTGGAGATGAACACATTTCTTTTACAACATCAAAAATTGGTTCCCTTATTGATGTCAATCAATCCAAGGATCCAGAAGGCTTACGAGTATTTTATTATCTTGTCCAGGACCTGAAGTGTTTGGTCTTCAGTCTTATTGGATTACACTTCAAGATTAAACCAATCTAGACTGAATATTGGTGTGGACATGGGGGGTGGGTGGGAGTAGAAAATTTTGTGTATATCAGGGCAGTATTTTTTTATGAACTATAAATGATTGTCTTTAATAAATATGTGATAAAATCCAATTTTTATTATTTTATAAAGACCTGAA

Publications

PMID - Link Title