Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SRSF6P2
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr20). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:16616150-16618019  UCSC
Coordinates (T2T) chr17:16518394-16520263  UCSC
Coordinates (hg19) chr17:16519464-16521333  UCSC
Strand -
Parental Sequence NM_006275.6
Parental seq. overlap 1074 bp
Parental seq. overlap (%) 21.3%
Genomic Region Intergenic
Retrocopy Summary SRSF6P2, located on chr17:16616150-16618019, is a retrocopy of the parental gene SRSF6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SRSF6
Full Name serine and arginine rich splicing factor 6
Also known as B52|HEL-S-91|SFRS6|SRP55
Coordinate chr20:43457896-43464243
Strand +
Gene summary The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SRSF6P1
Bonobo Pan paniscus SRSF6P1
Gorilla Gorilla gorilla SRSF6P1
Orangutan Pongo abelii SRSF6P1
Gibbon Nomascus leucogenys SRSF6P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SRSF6P2
TAAGTATTTCAGCCAGATCTGCTGGCAGGGTTTTTTTGTTGTTTTATTTGTTTGCTTATTTTTAAATTAACTGTTTTGAGCTTTGAATGCTTAAGGCTTTAGAGGGAGAACCCAATTTTCAATTATGTTGGCTTTTTATAAAGCTTGAGTTATGTAAGATTTAAATAGAAGTTTGCTACCAAGATGATTGCCTTATTGAATAGGTCACTATTAAATTCCTTTAAATGTTGATATCTGCCATTTGTGGAAACAACGTAAATTCTACTTTAGTGTAAACAAGGCAAGCCTCAGACCAGCAATAAATTATTCAGTTTGGATAACATTATTTTGTGCTGTTAATCAAATTTGCCAAAGTCTTTATCTGCCCCTTTAACAAGTTGAGTAAAAATAAAAGGTATTTAGATTAACTCAGAACTCTCTTGTTGTCTGCACACTATTATGGAACACTTTCCTGCTTAGGCAGTTACTCTTCCATGTTTATACTTGGTCTCTTCTGCAAGAGGAATCTCTTGAAAACAGGGGCACACAGAAATTTGATATGTGGCCAAATTGGATGAAAAAGATGAGGTTTAAGGAAATGGTGGCATGAAGACCCTCTCCCTTCTTTGTAGAATTAAGATAACTATGATTTTATAGCTTTTGAGCTAACATAACTTTTGTAAAGATTAAGCTCATTTAGTTATTGTGTGGCTGGACTCGGCCGCCACTATGGTGTGAGGCGCGTGTTCGGGCTCTTGCCGTCCCCGCACCCGCACCGCGGCTACTGGCTTGCGGTCCGCCGTTCCACAACCAGCCCTTGGGCCCCCGCCCGCCACGGACATGCCGCGCGTCTACATAGGACGCCTAAGCTACAACGTCCAGGAGAAGGCCATCCAGCGCTTTTTCAGTGGCTATGGCCGCCTCCTCGAAGTAGACCTCAAAAATGGCTACGGCTTCGTGGAGTTCGAGGACTCCCGCGACACCGACGACGCCCTTTACGAGCTGAACAGCGAGGAGCTCTGCGGCGAGCGCGTGATCGTAGAGCACGCCCGGGGCCCGCGTCGCAATCGCGACAGCTACAGCTACGGAAGCCGCCGTGGTGGAGGTGGATACAGCAGTCGGAGACATCTGGCAGAGACAAATACGGACCACCTGTTCGTACAGAATACAGGCTTATTGTAGAAAATCTTTCTAGTCTGTGCAGTTGGAGAGATTTAAAGGATTTTATGCGACAAGCAGGTTAAGTAACCTGTGCGGATGCCCACAAGGAAGGAACAAATGAGGGTGTAATTGAGTTTCGCTCCTACTCTGACATGAAGCGTGCTTTGGACAAACTGGATGGCACAGAAATAAATGGCAGAAATATTAGGCTTATTGAAGATAAGCCACGCACAAGCCATAGGCGATCTTACTCTGGAAGCAGATCCAGGTCTCGATCTAGAAGATGGTCACGAAGTAGGAGTCGCAGGAGCAGCCGCAGTAGATCTGGAAGTGTCTCAAAAAGTCGCTCCCGTTCCAGGTCGCGGAGCAAAGGTCGATCACGTTCTCGATCAAAAGGCAGGAAATCTAGATCAAAGAGCAAATCTAAGCCCAAGTCTGATCGGGGCTCCCATTCACATTCTCGAAGCAGATCTAAGGATGAGTATGAGAAATATCGAAGCAGGTCTCGGTCCGGATCCCCCAAAGAAAATGGAAAGGGTCATACAAAGTCAAAATCCAGATCAAGGAGCCAGTCCCGTTCCAATTCGCCGCTACCTGGTCCACCCTGAAAGGCCCGCTCTGTGTCCCCTCCACCAAAAAGAGCTACTt
>NM_006275.6
ATTGTGTGGCTGGACTCGGCCGCCCCTGTGGTGTGAGGCGCGTGTTCGGGCTCTTGCCGTCCCCGCACCCGCACCGCGGTTACTGGCTTGCGGTCCGCCGTTCGACAACCAGCCCTTGGGTCCCCGCCCGCCACGGACATGCCGCGCGTCTACATAGGACGCCTGAGCTACAACGTCCGGGAGAAGGACATCCAGCGCTTTTTCAGTGGCTATGGCCGCCTCCTCGAAGTAGACCTCAAAAATGGGTACGGCTTCGTGGAGTTCGAGGACTCCCGCGACGCCGACGACGCCGTTTACGAGCTGAACGGCAAGGAGCTCTGCGGCGAGCGCGTGATCGTAGAGCACGCCCGGGGCCCGCGTCGCGATCGCGACGGCTACAGCTACGGAAGCCGCAGTGGTGGAGGTGGATACAGCAGTCGGAGAACATCTGGCAGAGACAAATACGGACCACCTGTTCGTACAGAATACAGGCTTATTGTAGAAAATCTTTCTAGTCGGTGCAGTTGGCAAGATTTAAAGGATTTTATGCGACAAGCAGGTGAAGTAACCTATGCGGATGCCCACAAGGAACGAACAAATGAGGGTGTAATTGAGTTTCGCTCCTACTCTGACATGAAGCGTGCTTTGGACAAACTGGATGGCACAGAAATAAATGGCAGAAATATTAGGCTTATTGAAGATAAGCCACGCACAAGCCATAGGCGATCTTACTCTGGAAGCAGATCCAGGTCTCGATCTAGAAGACGGTCACGAAGTAGGAGTCGCAGGAGCAGCCGCAGTAGATCTCGAAGTATCTCAAAAAGTCGCTCCCGTTCCAGGTCGCGGAGCAAAGGTCGATCACGTTCTCGATCAAAAGGCAGGAAATCTAGATCAAAGAGCAAATCTAAGCCCAAGTCTGATCGGGGCTCCCATTCACATTCTCGAAGCAGATCTAAGGATGAGTATGAGAAATCTCGAAGCAGGTCTCGGTCCCGATCCCCTAAAGAAAATGGAAAGGGTGATATAAAGTCAAAATCCAGATCAAGGAGCCAGTCCCGTTCCAATTCGCCGCTACCTGTTCCACCCTCAAAGGCCCGTTCTGTGTCCCCTCCACCAAAAAGAGCTACTtcaagatcccgttctagatctcgctcaaagtcaagatcaaggtccaggtcgagttccagAGATTAACTCAGAACTCCTTGTTTGCACATTATTATGGAACACTTTCCTACTTAGGCAGTTACTCTTCCATGTTTATACTTGGCCTCTTCTGCAAGAGGAATCTCTTGAAAACAGGGGCACACAGAAATTTGATTTGTGGCCAAATTGGATGAAAAAGATGAGGCTCTAAGGAAATGGTGGCATGAAGACCCTCTCCCTTCTTTGTAGAATTAAGATAACTTTGATTTTATAGCTTTTGAGCTAACGTAACTTTTGTAAAGATTAAGCTCATTTAGTGTTGtttttttttttttttttttttttttttttttttttttAGTATTTCAGCAGGATCTGCTGGCAGGGTTTTTTTGTTTTATTTGTTTGCTTATTTTTAAATTAACTGTTTTGAGCTTTGAATACTTAAGGCTTTAGAGGGAGAACCCAATTTTCAATTATGTTGGCTTTTTATAAAGCTTGAGTTATGTAAGATTTAAATAAAAGTTTGCTACCAAGATGATTGCCTTATTGAATAGGTCACTATTAAATTCCTTTAAATGTTGATATCTGCCATTTGTGGAAACAACGTAAATTCTACTTAAGTGTAAACAAGGCAAGCCTCAGACCAGCAATAAATTACTCAGTTTGGATAACATTATTTTGTGCAGTTAATCAAATTTGCCAAAGTCTTTATCTGCCCCTTTAACAAGTTGAGTAAAAATAAAAGGTATTTTTTAGTCAATGTGTTCCATGATTTTGCTTAAATTAATACTTTTAAGTAATGGAACTTTTTTCAAAGGCAAATTTAAACTATTTAAGAAATAGCTCCTAATACTTGGGATCTTGTTTAGAGAATCCACTTTCTGGAAGTTCTCAGCATAATTAGTGTTGAGAGTGGTTCAGTTGTCTTTAATGTTTGTCATGTGGAAATGGAAGTAGCCTCTTTTTGTTCTGAAATTGAGTTTATTCAAAGTGTAAAAGCACATACTGCATTTTCTGCTGAAAGATCATTATGTTTAACAGGCACTTAATCTCAGTAAAGTCAGTTGCCAGTTAAGTTCCACCCAGTAGTCAGTCCCCTTTGTAGTTAGTGGGATTATTTGATAATTGGTTAGATCATACTTGTAAATTTTAATGCTTTGTGTAATTGGTTTGAAAAACAGTGAAATGGGTAAACGCAAAACTTTTGTACTTTATTACGAGTAAAGTGTAATGAGTACTGTGGAAACCAAATTTGAATACTGCAAATTTGTAGGAGTTACTAGGTTAGCAATTAGTCCATACATCCATAAGCCTGATGAGTTGAAATTGCAGTTTGAGAAGTGAATTAACCTTACATCCCTTTGTTCAGATACCTTAAAAGTTACTTTATTTAAAAGCATTTATTAATCTTAGTCTGAAATCAAAATATAGATTAATTGGCTCAGCTTTAATACCTTTCTAGGAGGTGTCACAATGTAGGGTACCAAGGGTTGGATTGTGATGGGGCATGGTCGTACACTGCTCATTGTGCCACAGGTGTGACTGGAAAGCATGATATTCTAGGGTTGGTTTGTAGATTCAAATAATCCAGAAATATACCTAATAAGATTGAGTGAAAAATTTGAGTCAAATATCTAGGGCATTCACAGAGTAGCTGTGAGTTCTTGGTAATGTGAAAAAGGCCTTGTTTTTCAGAAATTCCTGGGTTTCCTGTTAAAAAATCTTAAAGCCCAACCTTAGGAATATAGTGCCCCAAAAGGCGGATGCTTCTTCCATTATCTTATTTTCTTTGATACTTTATTTAATTAGATGTTTATAAAGAAATGGGTTTATTTTTCCAGCATAAACCTCAGAATTTAAGGAAAGAAAATGATGTCTGTTGTTATAGTTCATTGTTTTGCCTACTCAGCAGAAGTGATGACTCTTAAAAATTGGCTTTGACCAAAGTTCTCTTGTTTTCAGGGAAAGAACATAAAAGCTTTTTGAACTACAGCCTTTTTAAAAGAGGGATGGGAGGATATTACAGTAAGAAATTAGGCTTTCTAAAAGTATGAAACATCCTTCAACTGGGCTCTCTTGTTAATAGGACATCATATGGTAATAGACTGGTTTGACTATATTGTTAGCTGCCACAGTAAGCAGGTCATTGTATAGGTAAATGCCTGCACCCATAATTTTCTAGTAATAGCCACGACCAATTTATTAACAGTCAGGGCCTATCCTTGCCTGTAGTTCTCAGTCACTGGATGCACAAAATCACTGTGTAACATTGGCTCACTTGGTGAGCATAGGGTTGACTGATAAAATGTTTAATTCCCTTGCTAGCTTGTGAGAAGAATGAGTTGATGACATGCTCCATACCAGTGGCTAGATGGAGTATTAAGGTGGAGCAGAAAAGAAGTGAGAACATCTTGATTCCCCTTTCTTTTACTTGATGGTGTTTATGAACATGCCGTAGTGCCTTTATGGCCAGTTTGAGTCCTGCCTACTTTGACTTTTACGTTCCCATTCCTGTGTTACCACCTTCCTCCCGATTTGTTCACCTATTTTGTGCTTTAAATCTCAATAAAATACTTACTGAGGGAAAGGCTTGTTTTGAGTTTATTGCATATGCCCACTTAGGACCAGATTCTTAACAAATGTTTTTTTGAATTGGAGTTTGCATTGGCAAGCCATTCCTGTCTTGAGTATGAGAACAGGATCTTGTGTTCACTTACCCAgaaacgtgagtttgggatttagtatatggtttatgttgggcaactcattaatcactgtgcttcagtgtcatccatgaaactagggataaaacatgcatgggatgtgaagattaaaagtcaagaatatgaacagtacaagagagtaccataacaaataCAATTTTATTTACAAATATACATGGTTGGACCATACCTTGGAATCTACTTGCTAATGCAGCTGCTGTTAACAGTTCTTGTATCTGCTCAAGAGATTTCTATGATCATATAAAAATGCCTTTTTAGGTTTTCAGTGTTCATGCCCTGAGTAGTAGTCTGCAGTTTGCTTTAATACATGGTAATACAGAGATCGGCTTTAAATGGCTGGCTGGTTACTGTTGAATGAATGTATGATAAATTTTTTTTCAGAACCAACAGTGTGAATAATCCTTTCAGTTGTCTATCAGCATGAATTTAAAAATTACTTTCAAGATTCAACATTACACAATAAAACTTAGAGTTCTTGCAA

Publications

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