Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KYNUP2
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Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:19082866-19085342  UCSC
Coordinates (T2T) chr17:19030860-19033331  UCSC
Coordinates (hg19) chr17:18986179-18988655  UCSC
Strand +
Parental Sequence NM_001199241.2
Parental seq. overlap 1196 bp
Parental seq. overlap (%) 7.8%
Genomic Region Intergenic
Retrocopy Summary KYNUP2, located on chr17:19082866-19085342, is a retrocopy of the parental gene KYNU. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KYNU
Full Name kynureninase
Also known as KYNUU|VCRL2
Coordinate chr2:142877664-143055833
Strand +
Gene summary Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KYNUP1
Gorilla Gorilla gorilla KYNUP1
Gibbon Nomascus leucogenys KYNUP1
Green monkey Chlorocebus sabaeus KYNUP1
Crab-eating macaque Macaca fascicularis KYNUP1
Rhesus Macaca mulatta KYNUP1
Baboon Papio anubis KYNUP1
Golden snub-nosed monkey Rhinopithecus roxellana KYNUP1
Marmoset Callithrix jacchus KYNUP2
Bonobo Pan paniscus Without Homology
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>KYNUP2
TTTTTATGTCCCCAAAATGCAGGATCTGCCTCCAGTTGATTTATCTTTAGTGAATAAGGATGAAAATGCTATCTATTTCCTGGAAAATCCTCTTGGCCTTCAACCAAAAATGGTTAAAACAGATCTTGAAGAAGAGCTAGTTGAGTGGGGCAAAATGGGAGCCTATGGTCACGAAGAAGGCAGCATCCTTGGGATACAGAGATGAGAGTATTGTAGGCCTACAGAAGGACTATAGGAGCCTACGAGAAAGAAATAGCCCTAGTGAATGCGCTGACTGTTAATCTACATCTTCTACTGTTACCATTACAGGTGTGAGCCACCGCGCCCAGCCTTAGTCCAGTTATTGTTTAAGCCTATACCAAATGGTATAAAATTCTTATAGAAGCCAAAGCTTTCTCTTTTAATCATTATACTGTTGAGTCACAGCTACGACTCCATGGAGTTAACATTGAGGAAAGGGGATTATAAAGCCAAGACGGGGGAGGAAACCTTAAGAATAAAGGATATTTAAAGGATATCCCTGAAGCAATTGAGAAGGGAGGAGGCTCAATTACAGCAATCCTGTTCAGTGGGCTGCATTTTTATACTAGGCAGCTCTTTAATATACCTGCTACCACGAAAGCTGGACAAGTGAAGGGATGTTTTGCTGGCTTGATCTAGCATGTACAGTTGGAAATGCTGAACTCACTTACGTGACAGAAGAGTTGACTTTGCCCACTGGTGTTCCCACAATAATTTGAATGCAGGAGCAGGAGGTCTGGCAGGTACTTTTTCCATGAAAAGCATGCCCGTATGATTAAAGCTGTGCTGCTGGGGTGGTTTGGCTGTGAACTCAGCACCAGATTTGAGATGGATAACCAACTGCAGTTAATCCCTGGGGTTAGTGGATTCCAAATTTCAAATCCTCCCATTTTGTTGGTCTGTTTCTTACAGTTTAGAGATCTTTAGGCAGGCAGCGATTAAAGCATTGTGGAGAAAATCTATTTTGCTGACTGGTTATCTGGAATACCTGATCTAGCACTGCTATGGCAAAAATAAAGCAGAATCTAAGAAGCCAATGGTGACCTGGAGGTGACCATTACTCCATCCCATATGGAGGATCAGGGCTGCCAGCTGACACTAACATTTTTCTGTTCCAAAGAAAGATGTTTTCCAAGAGGTAGAAAAAAGAGGAGTGGTTTATGACAAGTGGAATCCAAATGTCATTCAAGTGGCTCCAGTTCCTTTCTATCATTCTTTCCATGATGTTTATAAATTTATCAATCTGaTTTATCAGTCTGCTCACTTCTGTACTTCACTCTGCAGAAACAAAAATTAGCAGTGTTTTCTAGAACAATTTAAGCAAATTATACTGAAAGCTGATGTGTGTTTTTTTTTTTACCATTATTCAATTTTTAGTTATTGAAAGTATTTTACAATTGATTGCATGTAGCTGGCAGTAAGTAATATACTTTACAGAAAA
>NM_001199241.2
ACATTTTCAAGGAATTCTTGAGAGGTTCTTGGAGAGATTCTGGGAGCCAAACACTCCATTGGGATCCTAGCTGGAATATAAAGAATGGCTTATCAGTGGAGACCATCGACAGTTGAGAAAAGAAGAAGCCCAAAAAGTACAAGAATGAAAATCGAGAGTTTTTAGAGAACAACTTGTAATGGAGCCTTCATCTCTTGAGCTGCCGGCTGACACAGTGCAGCGCATTGCGGCTGAACTCAAATGCCACCCAACGGATGAGAGGGTGGCTCTCCACCTAGATGAGGAAGATAAGCTGAGGCACTTCAGGGAGTGCTTTTATATTCCCAAAATACAGGATCTGCCTCCAGTTGATTTATCATTAGTGAATAAAGATGAAAATGCCATCTATTTCTTGGGAAATTCTCTTGGCCTTCAACCAAAAATGGTTAAAACATATCTTGAAGAAGAACTAGATAAGTGGGCCAAAATAGCAGCCTATGGTCATGAAGTGGGGAAGCGTCCTTGGATTACAGGAGATGAGAGTATTGTAGGCCTTATGAAGGACATTGTAGGAGCCAATGAGAAAGAAATAGCCCTAATGAATGCTTTGACTGTAAATTTACATCTTCTAATGTTATCATTTTTTAAGCCTACGCCAAAACGATATAAAATTCTTCTAGAAGCCAAAGCCTTCCCTTCTGATCATTATGCTATTGAGTCACAACTACAACTTCACGGACTTAACATTGAAGAAAGTATGCGGATGATAAAGCCAAGAGAGGGGGAAGAAACCTTAAGAATAGAGGATATCCTTGAAGTAATTGAGAAGGAAGGAGACTCAATTGCAGTGATCCTGTTCAGTGGGGTGCATTTTTACACTGGACAGCACTTTAATATTCCTGCCATCACAAAAGCTGGACAAGCGAAGGGTTGTTATGTTGGCTTTGATCTAGCACATGCAGTTGGAAATGTTGAACTCTACTTACATGACTGGGGAGTTGATTTTGCCTGCTGGTGTTCCTACAAGTATTTAAATGCAGGAGCAGGAGGAATTGCTGGTGCCTTCATTCATGAAAAGCATGCCCATACGATTAAACCTGCATTAGTGGGATGGTTTGGCCATGAACTCAGCACCAGATTTAAGATGGATAACAAACTGCAGTTAATCCCTGGGGTCTGTGGATTCCGAATTTCAAATCCTCCCATTTTGTTGGTCTGTTCCTTGCATGCTAGTTTAGAGATCTTTAAGCAAGCGACAATGAAGGCATTGCGGAAAAAATCTGTTTTGCTAACTGGCTATCTGGAATACCTGATCAAGCATAACTATGGCAAAGATAAAGCAGCAACCAAGAAACCAGTTGTGAACATAATTACTCCGTCTCATGTAGAGGAGCGGGGGTGCCAGCTAACAATAACATTTTCTGTTCCAAACAAAGATGTTTTCCAAGAACTAGAAAAAAGAGGAGTGGTTTGTGACAAGCGGAATCCAAATGGCATTCGagtggctccagttcctctctataattctttccatgatgtttataaaTTTACCAATCTGCTCACTTCTATACTTGACTCTGCAGAAACAAAAAATTAGCAGTGTTTTCTAGAACAACTTAAGCAAATTATACTGAAAGCTGCTGTGGTTATTTCAGTATTATTCGATTTTTAATTATTGAAAGTATGTCACCATTGACCACATGTAACTAACAATAAATAATATACCTTACAGAAAATCTGATATAATTTTTCAGAGTCTGTGGCACTAAGGAGTCCACAGGGCTGCCTAGGTGCTTTGTGTTTGGGGGACCAAAACTGTGTTGGTTCAAGTATTATCTATACAGTCTCTATAAGCTGTCACATTTCATGGTCATTGAAATGTTTTATGTTGGTTTAATTTCTGATTTAACTGACAACTTCATAATGTATGTGCAATTATTGTGTCAAATTTAGAAATATTACTTTAGCTTCAATTTACCAAGGAGTTTCTTTGAAGCATTGTAGTCTGatatatatatatatatatatatatatatatatatatatatatatatatgtgtgtgtgtgtgtgtgtatatatatatatatatatcatatatatatGATAGTGGCTTTCAAATTTTTTTGGGTACAATCCACATTGCTCCTGCTGATCTGTAATATCAGAAACCAGTATTTATGTGAATATATGAGAAATAttattgattctaagatattttatcatattttaacatctttgaaagaggacccatctttcaattttcgatcaatagtttcttacagtcaccattggccaTCTTTCTCGTTACCATCTATGAAATTAGCATGCATCTCAAATAAACAGTTACCATCTTCTATTTGATAAAATAGTCTAAATAGCAAAAATAAAAGTTTTTACAATTATTTGCCtgtgctctaataggtactattctattttatctcataagaaatgttggaaactcattatattgatttccttacccactcatgggccctaattcacactttTTAAGAATGTTTCTTTCTTTAATGTTATCATAATCTCTTACTTTTTAAATGAGAACTTCCCCTAATATAAGAGCTTAGATATTATATTACTATGTTTCCATAGTAAATAAATAACCCCAAGATCTTTTTGGGGATTAGAGATATAAGAAATATGTGCTCCATCTCTTGACATCTTTATCTCAAATCTATGGACCTTTCTTACCCACTGTGAAAAACCTAAAGTTACACTTAGCCCTGTTGGACTTACCTAGTTTTCAATTGTTGATGCCACAATCATTATTTATAAGTTGACAAAATAGTGTAGATTTGTATACATAGTCAACAAAAAGAGTGACATAATTATTGCCTCCAATTAAACAAGTTTGAATGAAATAAACAAACTTAGATAAACACTTCGGATGGTAGACGTAAACAATAATATGTGGAACTCCAACATCAACACCTACCaataccagtaactactgatatttatcatgtacttaccatgtaccatgtattgtgctacattactcatgttatctcccttaatTGAGTGGCTACATACTGCTTTAGCAAATCTTCCTACTGTAACTAATCCTCATAGATGGAAGAGTTCTCAAAACCTTAAAACTCATGCATAAGTGGATTCatatacatatataaaaatatatataaatatatatactttatatatatttatatttatatatttatatatttatattttaatatatttatataaatatatataaagtataatatatataaagtataaatatatatatatttatactttaagttcttggatacacgtgcagaacatgcaggtttgttacataggtatacatgtgccgtggtggattgctgcacccatcaacccgtcatctacatcaggtatttctcctaatgctcaccctcctcttatccccaactacccaaaaggacctggtgtgtgatgttcccctccctgtgttcatatgttctcattgttcaactctcacttatgggtaagaacatgcagtgtttgattttctgttcctctgttagtttgctgagaatgatggtttccagcttcatccatgtccctgcaaaggacatgaactcattcttttttatggctgcatagtattccatggtatatatgtgccacattttctttatccagtctatcattgatggccatttgagttggttccaagtcttcgctattgtgaatagtgctgcaatgaacatatgtgtgcatgtgtctttatagtagaatgatttataatccttagggtatacccagtaatgggattgctgggttaaatggtatttctggttctagatcctcgaggaattgccacactgtcttccacaatggttgaactaatttatactcccaccaacagtgtaaaagcattcctatttctccacatcctctcagcatctgttgtttcttgactttttaatgattagcattctaactggcgtgagatggtatttcattgtggttttgatttgcatttctctaatgaccagtgatgatgagttttttttcatatatttgttggccgcataaatgtcttcttttgagaagtgtctgttcgtatccttcacccactttttgatggggttgtgtttttcttgtaaatttatttaagtcccttgtagattctggatattttccctttgtcagatggatagattgcaaaaattttctcccgttctgtaggttgcccgatcactctgatgatagtttcttttgctgtgtagaagctctttagtttaatcaggttccatttgtcagttttggcttttgttgcaattgcttttggtgttttagtcttaaattctttgcccatgcctatgtcctgaatggtattgcctagatattcttctagggttttttttttggctttaggtcttgcagttaagtctttaatctatcttgagttaatttttgtataagatataagaaaggggtccagtttcagttttctgcatatggctagccagttttcccaacactatttattaaatagggaatcttttccccattgcttgtttttgtcaggtttatcaaagatcagatggttgtaaatgtgtggtgttatttctgaggcctctgttttgttccattggtctatatgtctgtttttgttcagtaccatgctgttttgtttactatagccttgtagtatagtttgaagtcaggtagtgtgatgcctccagctttgttctttttgcttaggattgtcttggcaatacaggttcttttttggttccatatgaaatttaaagtagttttttctaattctgtgaagaaagacaatggtagcttgatggaaatagcattgaatctataaattactctcagcaatatggccattttcaggatattgattcttcctatctatgagcatggaatgtttttccatttgtttgtgtcctctctggtatccttgagcagtggtttgtagttctcattgaagtagtccttcacatcccttgtaagttgtattcctaggtattttattctctttgcagcaattgtgaatgggagttcactcatgatttggttctctgtttgtcctatatacatatgttggtatataggaatgcttttattttaaagatggaagatgatgtctctctatgtaactcaggcaggtctcaaactcctgggctcaaatgatcctcctaccttaacctcctgagtagctgagactttagtcacacaccaccatgcctgacCAGGAATTGTTTTTCAACTTCATAGTGGTAAACAAAACATATGTGTTTTCAGTTCTCATGGAACAAGCAGCTTAGTAGGAGAAACATATGTTGAACTTGTAAGCAGAGAAGTAAATCTATAATGACAAATCATAATTTCTGAAGGGTATTAATTAGATGTTTGAGTGAGGGGAAATATTGGAAGGTGCTCATAAGTTTATAAATGttctaaaatatttcatgctaatcacattaaaattatatcaaagtatataaacatatcatggaaaacataatcagcaccatgtactcaacacctaggttaaaaaatagcattaaaaattctctttccagctcacattctgctccctccccaaatccacagataaccatcgaattatattttgttttcttcattcccttactttctttaagttttacacccatgtatgtacccataaaaatctattagctaattttggttgtgcatgaatattgtatcaatgcaattatactgtatatattctgcttttgcacatatttttagattcatccatttgtggcatgtagctttccattcattttcactgctgctcagtattgtattACAAATTTTACATTTGTTTTAGGGAAGAGTCATAAACCATCTTTAAGTTCTCCTATGTTACAAGTAATTTTGTAAATGATGTGAGGTGGTGATTCTATTTCATTTTTTCCCATATAGATAATTTATATTATTAATAATTCCTTCTATTTCATAAGCCAGGTTTCtatatatctatataaatatagatatgtagatatatGAAAGCAatatatatatggatgtctttctgggctatctgtactttcacactggctaatttgcttgttttttcatcaatacttcacttccttaattactacaacatagcagggcctggcatctgctagattaaatctctcagcttctttttattaagattgccctgaattgtcctggttatcctgggccccctactttttttatatttttgaatacatctaaataaatttagaataaatctattgtgttccataaaacccctgttgggatttcaattgaactgcaattaaattttagatcagttttggaagaattgactcaatagtgagccttcctacccaagaccatggcatttattttcatttatttatgatttctttaatgcttctcaaaattttttattttctctattatggaaacgcacatttatagtttgacaaattcctaagtacttCTAATTTTATTGTCATTCCACATTATCttttttgttgttgttttaaaagacagggtctccctctgtcacccaggctggagtgtactgatgtgattatagctcactgcagtctcaacctcctgggctcaagtgatcctcccacgtcagcctgtggagtagctaggactacaggcatgtgccacaatgcctggctcatttttaagtgttaagttaaaaaaagttgtagaaacagtgttttgctacatttcccaggctggtctcaaactcctggccccaagcaatcttcctgcctcagcttcccatattcggattatacgcatgaggcattgcaccagcccCATGTGTTATCTTTTATAAAATTTAACATTTAACTGATAATTGATACTGTATATACATGAATTCAATTGGTATCTATTTTTAATATGGGAAATTTTATGCAAATGAGCACATTtttctcccttccttccttccttctttccttgttctctttctttctctctctttctctttctctctttctttctttctttctttctcacagggtgtcactctgttgcccaggcggagtgcagtggcacatgatcatagctcactgcaacctccaactcaaacacttgagtgatcctctgtcccccgtttcccaagcagctgggactacaggcacatgccacgatgccaagctaatttttaaaaataattttttttgtagattcagagtcttgctatgttgcccaggctaatctcaaactcctggcctcaagcagtcctccctcctcagcctcccattacaggcataagctgccactcctggACCTCttttttttttttttttttttttttttGAGGCagtctctctctgtcacccaggctggagtatagtggcacgatctcagctcactgcgggttcaagcaattttcatgcctcagcctcccaagtagctgggattacaggcatgggccactatgcccagctaatttttgtatttttcatagagacaggatttcaccatgttggctaggctggtatcaaactcctgacttcaggtgatccgcccactttgaccttccaaaatgctgggattacgtgtgagccaccaaacccagccCCTCATtttctttttgatttttatttattttcctctgtttttcttcttttggatttagggatgtgtgtgtggaggtgtattgagtccgttttttctttctatttgtgtggaaattatacacttattctttgttattttagcaattactctggctattttaacatgcaaatataatgaagtttagaattagccattttttataactctccttctgactagttgaagaaatgagaatgctttaacatcaaacagccaactctttacttatacactattgctattcattatAGCATTTTTAGTCTAGCTTCCTCCCTCctctttctctctctctctctctgtctctctctctctcACTAATGTTTGCTATTTCTCCCTACAATTCAGAATTTTATTTATGGAtgaagtacatatataatttattacaattcattttaatgaaaaacttttagtggtaaattgtattagtctttgggaaaaaacatttattgataccattttctcattacttaaaaatagtttcacttcatatagaattctatgtcgacagtaattttctttcaggaagtagaaaatattaagttacagtattttggcttccattactgctgttaagCATTCAgatcatcagagaaatgcaaatcagaaccacaatgagatgccatctcatgccagtcagaatggcaatcattaaaaagtcaggaaacaatagatgctggtgaggctgtggagaaataagaatgcttttacactgttagtgggaatgtaaattagttcaaccattgctcttaagggctctttgtctttaatgatccgcatttttattatgatgtgtctaggcagttattattgtgtttattctatttctttatttgctgtctatccaagatttgaggattaattttttaatttctagaaaattcagaagtattatttatttattcaattattacctctttctattatttcctttttaaaataaaagggtatatgttagaatttttcactctctcctttatgcctttaacttcatattttctatttctttgaatttctgggctgcattctTAAGAATTCTAAAACATATATTTTAGTTTCTAAAAGTTTCATTAGATTTCTGTTCAAAATTCCTTCCATTTGTGATCTTTCGAATGTGCTTCTGCTTTAGGCATTAGTAGTGGACATTCTGGTTCCCCATTGAGCTTCCCTGCATCAGCTGTTTTGCCTGGTGGCTGCCACCAACGCTTTTAGCTACCTCCCTCCTCAAACTTTGGGGTCAGGCCACACACTATAAAGGATTGGAAAAAAAAATGAAAATATGAAAAACTTACACTTTGTATCAGTCAGGAGAAGGATAATCTTCACACtacagtttatgcttcagaagccaccccttctctgtggattagaccatgactagaagtttcctgagaccatcccttgcccagctcttttggtgatccccttcacttcctctgttacaggtttccctgatgagcactccttcaataaaacatagtcatccaaatcccaatctcaagcacggtgtcacgggaacctgatctaagtcaGCATTTTCTTTATTCTTAATCACAACTAGTTGATAGTCCATATCTAATATATAATGAATGTACAgttgtttctgttggagttcacatatgatgccttgtttcctttgtagttttgtgattgatagcttcgaactgctcatttaccttgaccttttgaattctttgaaaactgagttaagtctgattttccagagtttttatgtttgcttctgtcagttgcagagaatcaatgagaagaacactttaaattcttgttttcggtttttttccaatcacataagtagGATTTACCTGAatatatatataatatataaacatatatttatataaaataaaaacatataaaatatgaaatatataatacagtataaaatctattttatgtaaaatctattttatgtaaacatgataattaaatatatatttaaataatataaatataataaatatTTGAAGCAATTGTATTTTTTAAAAatttcttctaaagaaaaccaggatacatgtgcagaacctgcaggtttgttacataggtatacgtgtgccatggtggtttgctgcacctattgacccgtcctctaagttccctcccctcacctcccaccccccagcaggccctggtgtgtgttgttcccctctctgtgtccatgtattctcgcctcccacttatgagtgagaacacgcgatgtttggttttctgttcctgtgttaatttgctgaggatgatagcttccagcttcatccacgtccctgcaaaggacatgatctcattcctcaatactatggctacgtagtattccatggtgtatatataccacattttcttcatccagtcATGCAAATTTATATGAATGTCAATTCTTTTATAGTGATCTTCTGGGGCTATTACAATATATAGGGCTGTTTTTTTAAAACTAATTATATTTATTTCATGTTGCTTTAACTTATTAAAAAACAGACTGAAGAAAGACTGGGTGTGAAGTCAGTAAATTAATTTCAAATTAAATAAACTTTTCTACAGCTATTTTATGCTCAATAACTTTCTACTTATTCTTGAGTTCAAAACTATATGGGTTCACATTTAAATTATATAGTGTATTTTCTCCATAAACTGAAGTTGTTAGAACATTGATTTTTTTAAGTAAATGGATTTTTGCACCACTTCAAGAAAGAAACCTTCAAACAGCCTGGAAATATCACATCAATAAAGCACAACCTGGGAATCAAAGTATTAGGGTACCTTGTTACTGAGATTATGGATGTGATGCTTCTGTGGGCCATTAGCATGTGCACTGTGTGTATGATATGCTCTATGTTCTCTTCCCACTAATAATTTTATTTTTAATTTCAGCAAGATTTAGTCTCAAATAACACAATAATAATGGAGGtcattgtgaagtagtggatgtaaatagatctgatgtggttttggtttattgcagtaattgttttgactaattctctagtttttcaacttttgattgtttaagatggttcttgagtccttttgacatgaccctatctatttttgataacttcatagcctttagtataaaaacaggtaggcttatattacatatttccaacttcaaacttgttatttatttatctaagactatacagttcttttcagagaaaaaccttctttataaaccagaatcttaacaggaagagtgctcattttaattgagctgatcatgtttctaggattttttagttaaaagaaaatacatattttaaaaatataaattatatttttatttcatagtggtattttcaattttgtctgggataataagatgttttatttaacttgtttgattttgtagttttatctttgtgggaaggacctggtaagaggtaattgaatcatgggggcaggactttcccatgatgttctcatgataatgaataagtttcatgagatctgttggtttcataatgtggagtttccctgcaaaggctcttgtcctgtctgtgccatttgagacatgcctttcaacttctgccctgattgtgaggcctcccccgccatgtggaattgggtcttacttttgtaaattgcccagtctcaggtatgtctttatcagcagcctgaaaactgactaatatagtaagttggcaccagtagagaggggcactgctgaaaaggtacccgaatatgtggaagcaactttaaactgggtaacaggcagaggttggaatggtttggagggctcataagaagacaggaaagtgtgggaaatttggaactccctagagacttgttgaatggctttaaccaaaatgctgataataatatgaacaatgaagtccaggctgaggtggtctcagacaaagataaggaacttcttgggaactggagcaaaggtgactcttgttatgttttagacataaagcaaagagactggaggcattttgcccctgccctagagatttgtgggacattaaacttgagacagattatttagggtatctggaggaagaaatttttatgcagcaaagcattcaagaggtgacttggttgctattaaaggcattcagttttaaaagggaaatacagcataaaagttcagaaaattttcagcctgacaatgcagtagaaaaggaaaaccaattttctgaggagaaatttaagctggctgcagacatttacataagtaacaagaagctgaatgttaatcactaagacaatgaggaaaatgtctccagggcatgtcagagacctttgtggcagcccctcccatcacagaccaggagctttagaaggaaaaatggcttcgtgggctggtcacagggtccctctgctgtgtgcagtctagggacttggtgccctgtgtcccagcagctccatccatgactaaaaggggccaaggtacagcttgggctgtggcttcagagggtggaagccccaagtcttggcagcttccatatggtgttgagcctgggttcacagaagtcaagaactgaggtttgggaacttacaccaagatttcagaggatgtatggaaatgcctggatgcccaggcagaagtttgctgcaggggcaaggccctcatggagaacctctgctagggcagtgaagaagggaaaagtatggtgggagcccccatacagagtccctactgaggcaccacctagtggagctttgagaagagggccactgtcctccagaactcaggatggtaaatccaccacgcacctggaaaagctgcagacaattccagcctgttaaagcagccaggagggggctataccctgcaaagccacaggggcggacctgctcaaggctgtgggagaccacctcttgcatcagtgtgacctggatgtgagacatggagtcaaaggagatcattttggagctttaagatttgactgccccactggatttcagactttcatggggcctgtagccccttcgttttggccaatgcctcccatttggagtggctgtatttacccaatgcctgtatccccattgtatctaggaagtaactaacttgcttttgattttacaggcccataggtggaagggcgatgtttctttctggaggctccagggagaactctgttttcttaccttttctggattctagaggcttcccacaatccttggcttaaggtccatctttaagctttgtctctgatgagactttggactgcggacttttgagttaatgctgaaatgagttaagactttgggtgactgttgcgaagacatgattggttttgaaatgtgagaacatttaagaggggccaggggcagaatgatatggtttgactttgtccgcagtcaaatctcatcttgaatttctatgtgtttggagaggtacccggtgggaggtaattgaatcatgagggcaggtcttttctgtgctgttctcatgatggtgagtaagtctcatgagatctgatggttttataaaggggagtttccctgcccaagttcttctcttgtctgccatcatgtgcgatgtgcctttcacctctgccatgattatgaggcctccctggccatgtggaactgtgagtccattaaacctctttcttttgtaaattgcccaatcttgggaatgtctttatcagcagtgggaaaacggattaatatactaatttatagctagtaggtaaaaagccagggacttgccattagcgttggaagtggggttgtgggggcagtcttgtggaactgagcccttaacctgtggggttgaatgatatctccaggtatatcatgtcagaattgaattcaattagaggatacctagcttgcgttcaatgcagaattgcttgctggtgaggagaaatccctatacacattttggtgaccagaggtaaagcattttatgttgattcttgagtgagagagtagaaataacactggttttttccCTATGTCCTTACAACCACCAATTGGATACATTGTTTCAGTattttgaaatttttcatttaatttttataaattttctttttaaattttagattctacaATATCTCCAATTCTTCAGTTTATTCCCTCTTACTATGTATAAGTATTTCCCCAAGTTTCACTTTATCTTTCTATTACTTTTTTTACATAATAGAGCTATAAAGGCAATTCACAATTCTCTCTTTTCTCATATATAATATAGAGCATATTATAAATACTCTACTTTggaaaattattctttataggaaattacagataatatttgatgaagaaaatcgaatataatcatttttcaatacttaggataacagattcaggcaaagataaaacattaaaggaaaagttagtgaaaactattaatatatagtggaggcatcacgttgttatgaacttcattgatcaatactgataccactaaaaatggaacaacatgtaattatgtgctcaatgtgatgaatatgaagtagactgcaccactctgcagtacagtcaggaaataagaaaccaagtccaatcaaaatagccctaaagctaccttccagtttataaaaagtatgaagaatagaggggcaattaaatgataccataaagagtcaaatacagggcatgcaacatagctgctgattggatttattcaacatgtcagtggcatgaatacaataggaggcaggtagggagaaggcactaccctgaattatgagactgaagagatataataaacaaatgcaatgtgtggacttggttgggatcttcattcaaagaccaactataaaaagacattgttgtgagaattgaggaaatttgaatgagaaatgtatttttatctaatttgttagctgtgataatagtattgtgggagtaagaagctattcatatttctatatatatataccaagtacataggagtgaaataatacaaaatctggaatttgccttaaaatTCCTCTGCAAAATTATAAAAAAGAACGATGACAAACTAAAAAGGtgtagtattcttctatggctgctataacaaatgaccaaaaaacatagtgactgaaaataacccacatttattatcttacagttccataggttagaagttcaacatgggtctcatgagatcaaaagcaaggccttggcagggtgacgtttctttctggaggttccagggggaactctgttttcttactttttttagattctagaggcttcccacaatccttggcttaaggtccatctttaaagacagcaacgtttcatctctctacctattctttcatccttacatctttctctaactattccttttcttctgtcttccacttttaagagcctttttgagtctattgaggccaactggacaatcaaggattatctccctatgttaaggtcaattgattagtgacctaattccatctacaatcacaattcctctttgccatataatgtaaaatattcatacctctaaggattaggacatggacatctttgagggtcattagtcatcttaccacaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaggaaagggaggagaggagaggagaggtaggagggaagaagaaaAAAATAGTATGAAAAAATCTTGATAAATTTGAAAACTGGGTGAATAATATGTGGAATTCTCTCTATTTTTGTTAATGTTGGAAAATTTAATAAAAACAATGAACAGTGA

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