Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name OSTCP9
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:35005260-35006011  UCSC
Coordinates (T2T) chr17:35953176-35953927  UCSC
Coordinates (hg19) chr17:33332279-33333030  UCSC
Strand +
Parental Sequence NM_021227.4
Parental seq. overlap 693 bp
Parental seq. overlap (%) 64.8%
Genomic Region Intergenic
Retrocopy Summary OSTCP9, located on chr17:35005260-35006011, is a retrocopy of the parental gene OSTC. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name OSTC
Full Name oligosaccharyltransferase complex non-catalytic subunit
Also known as DC2
Coordinate chr4:108650599-108667820
Strand +
Gene summary Predicted to contribute to dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Part of oligosaccharyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes OSTCP7
Bonobo Pan paniscus OSTCP8
Gorilla Gorilla gorilla OSTCP4
Orangutan Pongo abelii OSTCP6
Green monkey Chlorocebus sabaeus OSTCP7
Crab-eating macaque Macaca fascicularis OSTCP8
Rhesus Macaca mulatta OSTCP7
Baboon Papio anubis OSTCP8
Golden snub-nosed monkey Rhinopithecus roxellana OSTCP10
Marmoset Callithrix jacchus OSTCP4
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>OSTCP9
ATGGGGCTTGAGGCCAAGAACAGCCCTTGTTGCCACCAACATGGAGACTTTGTACCATATCCCATTCTTAGTGCTCGAGTGTTCCAACCTGAAGTTGAAGAAGCCACCCTGGCTGCACATGCCATCAGCCATGACTGTGTATGCTCTGGTGGTGGTGTCTTACTTCCTCATGACTGGAGGAATAATTATATGATATTGTTGAACCCCCAAGTATTGGCTGATGAACGTGGGCATCAGAGGCCAGTAGCTTTCTTGGCCTACAAAGTAAATGGACAGTATATTATGGAAGGATTTGCATCCAGCTTCCTGTTTACAATGGGAGGTTTAGGTTTCATAATGCTGGACCAGTCGAATGCACCAAATATCCCAAAACTCAATCGATTTTTTTTCTTCTATTCATTGGATTCGTCTGTGTCCTACTGAGTTTTTTCATGGCTGGAGTATTCATGTGAATGAAACTGCCGGGCTATCTGATGGGTTAGAGCGCCTTTAAGAAGAAATCAGTGGATACTGGATTTGCTCCTGTCAATGAAGTTCTAAAGGCTGTACCAATCCTCCAATATGAAATGTGGGAAAGAATGAAGAGCAGCAGTAAAAGAAATACCTAGCGAAAAAAACAGGAAGCATATTGAAGCTCGGACTAGAATTTCTTCTTGGTATCAGAGAGACAAGTTTATCACAGTATTTTTTTTTTTCCTGCTGACCTATTGATAATACCAACAATGTTGAGTGGCATTTTCTTCTTAGTTTTT
>NM_021227.4
CTGTTTCCGGGAGGCGCGTGGGGCTTGAGGCCGAGAACGGCCCTTGCTGCCACCAACATGGAGACTTTGTACCGTGTCCCGTTCTTAGTGCTCGAATGTCCCAACCTGAAGCTGAAGAAGCCGCCCTGGTTGCACATGCCGTCGGCCATGACTGTGTATGCTCTGGTGGTGGTGTCTTACTTCCTCATCACCGGAGGAATAATTTATGATGTTATTGTTGAACCTCCAAGTGTCGGTTCTATGACTGATGAACATGGGCATCAGAGGCCAGTAGCTTTCTTGGCCTACAGAGTAAATGGACAATATATTATGGAAGGACTTGCATCCAGCTTCCTATTTACAATGGGAGGTTTAGGTTTCATAATCCTGGACCGATCGAATGCACCAAATATCCCAAAACTCAATAGATTCCTTCTTCTGTTCATTGGATTCGTCTGTGTCCTATTGAGTTTTTTCATGGCTAGAGTATTCATGAGAATGAAACTGCCGGGCTATCTGATGGGTTAGAGTGCCTTTGAGAAGAAATCAGTGGATACTGGATTTGCTCCTGTCAATGAAGTTTTAAAGGCTGTACCAATCCTCTAATATGAAATGTGGAAAAGAATGAAGAGCAGCAGTAAAAGAAATATCTAGTGAAAAAACAGGAAGCGTATTGAAGCTTGGACTAGAATTTCTTCTTGGTATTAAAGAGACAAGTTTATCACAGAATTTTTTTTCCTGCTGGCCTATTGCTATACCAATGATGTTGAGTGGCATTTTCTTTTTAGTTTTTCATTAAAATATATTCCATATCTACAACTATAATATCAAATAAAGTGATTATTTTTTACAACCCTCTTAACATTTTTTGGAGATGACATTTCTGATTTTCAGAAATTAACATAAAATCCAGAAGCAAGATTCCGTAAGCTGAGAACTCTGGACAGTTGATCAGCTTTACCTATGGTGCTTTGCCTTTAACTAGAGTGTGTGATGGTAGATTATTTCAGATATGTATGTAAAACTGTTTCCTGAACAATAAGATGTATGAACGGAGCAGAAATAAATACTTTTTCTAATTAA

Publications

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