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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RAB38P1
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:35409682-35409943  UCSC
Coordinates (T2T) chr17:36357656-36357917  UCSC
Coordinates (hg19) chr17:33736701-33736962  UCSC
Strand -
Parental Sequence NM_022337.3
Parental seq. overlap 219 bp
Parental seq. overlap (%) 15.3%
Genomic Region Intragenic (SLFN12)
Retrocopy Summary RAB38P1, located on chr17:35409682-35409943, is a retrocopy of the parental gene RAB38. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RAB38
Full Name RAB38, member RAS oncogene family
Also known as NY-MEL-1|rrGTPbp
Coordinate chr11:87809490-88175504
Strand -
Gene summary Enables several functions, including AP-1 adaptor complex binding activity; AP-3 adaptor complex binding activity; and BLOC-2 complex binding activity. Involved in several processes, including endosome to melanosome transport; melanosome assembly; and phagosome acidification. Located in several cellular components, including cytoplasmic vesicle; lysosome; and mitochondria-associated endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RAB38P1
Bonobo Pan paniscus RAB38P1
Gorilla Gorilla gorilla RAB38P1
Orangutan Pongo abelii RAB38P1
Crab-eating macaque Macaca fascicularis RAB38P1
Golden snub-nosed monkey Rhinopithecus roxellana RAB38P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RAB38P1
GGTGCATTGATTGTCTTCAGTATCACCAGCCCAGCCCCATTTGAAGCAGAGCCAAAGTGGAAAAATGATTTGGACTAAACGTTAACTCATGGCAGACCAGTTTCTGTGGTTCTGTTGGCCAAGAAATGTGACCATGGGAGGATGAATGCAGAAACAGCAGCCTCAAGATGGGCCAGATCTACATGGAACATAGTTTTGTAGGATAAATTGAAACATCAGCAAAAGAAAATGTGAACTTTGATGAAGCCTCCAGGTGCCTg
>NM_022337.3
GCGCAGAGCCCAGGCTGCGCTTCCCTGGTCAGGCACGGCACGTCTGGCCGGCCGCCAGGATGCAGGCCCCGCACAAGGAGCACCTGTACAAGTTGCTGGTGATTGGCGACCTGGGCGTGGGGAAGACCAGTATCATCAAGCGCTACGTGCACCAGAACTTCTCTTCGCACTACCGGGCCACAATCGGCGTGGACTTCGCGCTCAAGGTGCTCCACTGGGACCCGGAGACTGTGGTGCGCCTGCAGCTCTGGGATATCGCAGGTCAAGAAAGATTTGGAAACATGACGAGGGTCTATTACCGAGAAGCTATGGGTGCATTTATTGTCTTCGATGTCACCAGGCCAGCCACATTTGAAGCAGTGGCAAAGTGGAAAAATGATTTGGACTCCAAGTTAAGTCTCCCTAATGGCAAACCGGTTTCAGTGGTTTTGTTGGCCAACAAATGTGACCAGGGGAAGGATGTGCTCATGAACAATGGCCTCAAGATGGACCAGTTCTGCAAGGAGCACGGTTTCGTAGGATGGTTTGAAACATCAGCAAAGGAAAATATAAACATTGATGAAGCCTCCAGATGCCTGGTGAAACACATACTTGCAAATGAGTGTGACCTAATGGAGTCTATTGAGCCGGACGTCGTGAAGCCCCATCTCACATCAACCAAGGTTGCCAGCTGCTCTGGCTGTGCCAAATCCTAGTAGGCACCTTTGCTGGTGTCTGGTAGGAATGACCTCATTGTTCCACAAATTGTGCCTCTATTTTTACCATTTTGGGTAAACGTCAGGATAGAGATACCACATGTGGCAAGCCAAAGATCTATGCCTCTGTTTTTTCAGTGAGAGAGAAATAGCAAATGTTCTTTCTATGCTTTCCTCACCATCATCACAGTGTTTACAAACTTTTGAAAATATTTAGTCTGTTACAAACTTCTGTCATGTAGCTGACCAAAATCCTGCAGGGCCACAGTCGGCACTGTTATTTGCTTCTTTTAATCAGCAAAGGCCTCAAGTCTTAAAATAAAAGGGGAGAAGAACAAACTAGCTGTCAAGTCAAGGACTGGCTTTCACCTTGCCCTGGTGTCTTTTTCCAGATTTCAGTATATTCTCTGATGGCCTGACAGGCCTATTAAGTAGATGTGATATTTTCTCCCAAGATGACCTCCATTCTCGGCAGACCTAAGAGTTGCCTCTGAGTTAGCTCTTTGGAATCGTGAACACAGGTGTGCTATATTGTCCTTGTCCTAACTGTCACTTGCCATGGCCTGAATGTTGGCTTAACTGAATATTGTATGAAAAGACATGCCTCCATATGTGCCTTTCTGTTAGCTTTCTCTGACTCAAGCTGTGGGGCTCCTCtatacatgctatacatgtaatatatattatatatatTTTTGCAAGTGAACAATAAAACATTAAAAGATGCTGTTTCCCTA

Publications

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