Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Retrocopy Name VAMP5P1
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Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:46717766-46718325  UCSC
Coordinates (T2T) chr17:47579248-47579807  UCSC
Coordinates (hg19) chr17:44795132-44795691  UCSC
Strand +
Parental Sequence NM_006634.3
Parental seq. overlap 473 bp
Parental seq. overlap (%) 71.7%
Genomic Region Intragenic (LRRC37A2)
Intragenic (NSF)
Retrocopy Summary VAMP5P1, located on chr17:46717766-46718325, is a retrocopy of the parental gene VAMP5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name VAMP5
Full Name vesicle associated membrane protein 5
Also known as -
Coordinate chr2:85584431-85593406
Strand +
Gene summary Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes VAMP5P1
Bonobo Pan paniscus VAMP5P1
Gorilla Gorilla gorilla VAMP5P1
Orangutan Pongo abelii VAMP5P1
Gibbon Nomascus leucogenys VAMP5P1
Green monkey Chlorocebus sabaeus VAMP5P1
Crab-eating macaque Macaca fascicularis VAMP5P1
Rhesus Macaca mulatta VAMP5P1
Baboon Papio anubis VAMP5P1
Golden snub-nosed monkey Rhinopithecus roxellana VAMP5P1
Marmoset Callithrix jacchus VAMP5P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

This retrocopy transcript is not present in the GTEx database for expression quantification.

This retrocopy transcript is not present in the ARCHS4 database for expression quantification

Related Sequence

>VAMP5P1
aAGCGAACAAGGTGACGGAAATCACGCTTAACAACTTTGACAAGGTCCTGGAGCATGATGGAAAGCTGACCGAACTGGAGCAGCGTTCAGACCAACTCCTGGATATGAGCTCAGCCTTCAGCAAGACAACAAAGACCCTGGCCCAGAAGAAGTGCTGGGAGAACATCCATTGCCAGATCTACTTGGGGCTAGTGGTGGGTGGTAGCCTGCTCATCATCCTGATTGAGCAGCTGGCCATCTTTCTCCCTCAGAGTGACACCAGTAATGCCCCACAGACCTAGGATGCAGGCACCACCTCAGGGCCTGGGGACTGACAGCTGGTCCTGAGGGAGAAGCCAAATGGCTGCACTGGCTGGTTCCGGTCTCCAGAGAACCTTGGTGTTTGCTCTCCCCTGACCCACCCCAGTGAGTGCCAAAGGGCAGCCCCAACACGTGCACCCCTGCATTTCTTGTCATGCCACAGACTGGCCCTCGAGGGCACCCTGCCATACTGGCCATGCCGGGCCAGCCCCACCTGAAGCTCAGT
>NM_006634.3
ACTGCGGCCGCTCCGCAGGCAGAGAAGCCGGGAGCGGGCGAGGCGGCGGCGGCAGCAGCGATGGCAGGAATAGAGTTGGAGCGGTGCCAGCAGCAGGCGAACGAGGTGACGGAAATTATGCGTAACAACTTCGGCAAGGTCCTGGAGCGTGGTGTGAAGCTGGCCGAACTGCAGCAGCGTTCAGACCAACTCCTGGATATGAGCTCAACCTTCAACAAGACTACACAGAACCTGGCCCAGAAGAAGTGCTGGGAGAACATCCGTTACCGGATCTGCGTGGGGCTGGTGGTGGTTGGTGTCCTGCTCATCATCCTGATTGTGCTGCTGGTCGTCTTTCTCCCTCAGAGCAGTGACAGCAGTAGTGCCCCACGGACCCAGGATGCAGGCATTGCCTCAGGGCCTGGGAACTGACCCAGCTGGTCCTGAAGGAGAAGCCAAATGGCTGCACTGGCCGATTCTGGTCTCCAGAGGACCTTGGTGTTTGCTCTCCCTTGACCCACCCCAGTGAGTGCCAAAGGGCAGCCCCAACATGTGCACCCCTGCATTTCCTGTCATGCCACAGACTGGCCCTTGAGGGCAGCCTGCTGTACTGGCCATGCTGGGCCAGCCCCACCTGGAGCTCAGTAAAAACTGCTGTTTGATTAAAAGCTGGTATCTGTG

Publications

PMID - Link Title
No publications available for this retrocopy