Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name NFE2L3P2
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:47423452-47426692  UCSC
Coordinates (T2T) chr17:48286106-48289347  UCSC
Coordinates (hg19) chr17:45500818-45504058  UCSC
Strand +
Parental Sequence NM_004289.7
Parental seq. overlap 2798 bp
Parental seq. overlap (%) 74.1%
Genomic Region Intragenic (EFCAB13)
Retrocopy Summary NFE2L3P2, located on chr17:47423452-47426692, is a retrocopy of the parental gene NFE2L3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NFE2L3
Full Name NFE2 like bZIP transcription factor 3
Also known as NRF3
Coordinate chr7:26152198-26187137
Strand +
Gene summary This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla NFE2L3P1
Orangutan Pongo abelii NFE2L3P1
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NFE2L3P2
GTTGGCCACCGCGCCTGGCTGCGGGCGGCCGGGCGAACGGGCTCGGCGCGCAGGTGGCTCCTCCTTCGCTTCTCCCGATCCCCGGCCGTGCCAGGCACGGTGCCGGCTGCCGAGGGAACGCCTTTGTGCCCGGTCCTGGGAACCCGCGACGGCCGCCGCGCGCCCCGGTCCATTGTTTCGCTTCTCTGGGTTCCAGGTAGGTGCGGGCGGCGCGCGGGGTCCGCACGACGTGTCACCCCGGCGGTTGGGGCGCCGGGACCCGCGGGCGCCGGCAGGGGCGTTCCCGGGCGCACGGCGGCGGTGCAGCACCTGAAGCGGTGGTGGTCGGCCAGCGGCGGCCTCCTGCACCTCACCCTCCTGCACCTTACCCTCCTGCTGAGCTTTGCTGGGCTCCGTGTAGACCTAGACCTTTACCTGCTACTGCCGCCGCCCACCCTGCTCCGGGACGAGCTGCTGTTCCTGGGCGGCCCGGCCAGCTCCGTCTACGCGCTCAGCCCCTTCTCGGCCTCGGGAGGGAGGGGGCGCGCGGGCCAGTTGCACCCCAAGGGCCGGGAGCTGGACTCTGCCGCGCCGCCCGAGGGCCCGCTGCTCCGGGAGGTGCGCGCTCGGGGTCCCCTTCATCCCTCTCACCCCGGTGGATGCGTGGCTGGTGCACAGCGTGGCTGCCAGGAGAGCGGACGAGGCCCACGGGCTGCTCGGCGCCGCCGCCGCCTAGTCCACCGGAGGAGCCGGCGCCAGCGTGGACGGCGGCAGCCAGGCTGTGCAGGGGGGCTGCGGGGACTCCCGAGCGGCTCGGAGTGGCCCCTTGGACGCCGGGGAAGAGGAGAAGGCACCCGCGGAACCGACGGCTCAGGTGCCGGACGCTGGCGGATGTGCGAGCGGGGAGAACGAGGTACTAAGAGAAAAGCACGAAGCTGTGGATCATAGTTCCCAGCGTGAGGAAAATGAAGAAAGGGTGTCAGCCCAGAAGGAGAACTCACTTCAGCAGAATAATGATGATGAAAACAAAATAGCAGAGGAACCTGATTGGGAGGCAGAAAAGACCACTGAATCTAGAAATGAGAGACATCTGAATGGGACAGATACTTATTTCTCTCTGGAAGACTTATTCCAGTTGCTTTCATCACAGCCTGAAAATTCACGGAGGGCTTCTCATTGGGAGATATTCCTCTTCCAGGCAGTATCAGTGATGGCATGAATTCTTCAGCACATTATCACGTAAACTTCAGCCAGGCTATAAGTCATGATGTGAATCTTCATGAGGCCATCTTGCTTTGTGCCAACAGTACATTTAGAAGAGATCCAATAGCAAGGACTTCACAGTCACAAGAACCGTTTCTAAAGTTAAATTCTCATACCACCAATCCTGAGCAAACCCTTCCTGGAACTAATTTGACAGGATTTCTTTCTCCGGTTGACAATCcCTCCGGTTGACAATCTTATGAGGAATCTAACAAGCCAAGACCTACTGTATGACCTTGATGTAAATATATTTGATGAGATAATGTCATTGGCCACAGAAGACGACTTTGATCCAATCGATGTTTCTCAGCTTTTTGATGAATCAGATTCTGATTCTGACCTGTCTTTAGATTCAAGTCACAATAGTACCTCTGTCATCAAGTCTAATTCCTCTCACTCTGTGTGTGATGAAGGTGCTATAGGTTATTGTACTGACCATGAATCTAGTTCCCATCATGACTTAGAAGGTGCTGTAGGCAGCTACTACCCAGAACCCAGTAAGCTTTGTCACTTGGATCAAAGTGATTCTGGTTTCCATGGGGATCTTACATTTCAACACATATTTCATAACCACACTTACCACTTGCAGCCAAGTGCACCAGAATCTACTTCTGAACCTTTTTCGTGGCCTGGGAAGTCACAGAAGATAAGGAGTAGGTACCTTGAAGACACAGATAGAAACTTGAACGTGATGAACGGCGTGCTAAAGCTTTGCATATCCCTTTTTTCTGTAGATGAAATTGTCGGCATGCCTGTTGATTCAATAGCATGTTAAGTAGGTACTATCTGACAGACCTACAAGTCTCACTTATCCGTGATATCAGACGAAGAGGGAAAAATAAAGTTGCTGCGCAGAACTATCGTAAACGCAAATTGGACATAATTTTGAATCTAGAAGATGATGTATGTAACTTGCAAGCAAAGAAGGAAACTCTTAAGAGAGAGCGAGCACAATGTATCAAAGCTATTAACATAATGAAACAAACTGCATGACCTTTATCATGATATTTTTAGTAGATTAAGAGATGACCAAGGTAGGCCAGTCAATCCAAACCACTATGCTCTTCAGTGTACCCATGATGGAAGTATCTTGATAGTACCCAAAGAACTGGTAGCCTCAGGCCAGAAAAAGGAAACCCAAAAGGGAAAGAGAAAGTGAGAAGAAACTGAAGATGGACTCTATTACGTGAAGTAGTAATGTTCAGAAACTGATTATTTGGATCACAAACCATTGAAACTGCTTCAAAAATTATATCTTTAAGTACTGCTACTTGAATAACTCAGTTAAGGCTCTGTTTTGAAGCTTACATGGACAAATGTTTAGGACTTCAAGATCACACTTGTGGGAAATCTGGGGGAGCCATAACTTTTCATGAAATGCATTGTATACAAAATTCATAGTTATGTCCAAAGAATAGGTTAACATGAAAACCCAATAAGACTTTCCATCTTGGCAGCCATCCTTTTTAAGAGTAAGTCGGTTACTTCAAAAAGAGCAAACACTGGGGATCAAATTGTTTTAAGAGGTATTTCAGTTTTAAATGCAAAATAGCCTTATTTTCATTTAGTTTGTTAGCACTATAGTGAGCTTTTCAAATACTATTTTAATCTTTATATTTAACTTATAAATTTTGCTTTCTATGGAAATAAATTTTGTATTTGTATTAAAAATAAACTTCCCTTTTATACAGAA
>NM_004289.7
GGAGCTTGGCCACCGCGCCGGGCTGCGGGCGGCTGGGCGAACGGGCTCGGCGCTCAGGTGGCTCCTTCTTCGCTTCTCCCGATCCCCGGCGGTGCCAGGCACGGTGCCGGCTGCCGAGGGAACGCCTTTGTGCCCGGTGCTGGGAACCCGCGACGGCCGCCACGCGCCCCGGTCCATTGTTTCGCTTATCTGGGTTCCAGGCAGGTGCGGGCGGCGCGCGGGGTCCGCACGTGTCACCCCGGCGGCTGGGGCGCCGGGACCCGCGGGCGCCGGCAGGGGCGTTCCCGGGCGCGCGGCGGCGATGAAGCACCTGAAGCGGTGGTGGTCGGCCGGCGGCGGCCTCCTGCACCTCACCCTCCTGCTGAGCTTGGCGGGGCTCCGCGTAGACCTAGATCTTTACCTGCTGCTGCCGCCGCCCACCCTGCTGCAGGACGAGCTGCTGTTCCTGGGCGGCCCGGCCAGCTCCGCCTACGCGCTCAGCCCCTTCTCGGCCTCGGGAGGGTGGGGGCGCGCGGGCCACTTGCACCCCAAGGGCCGGGAGCTGGACCCTGCCGCGCCGCCCGAGGGCCAGCTGCTCCGGGAGGTGCGCGCGCTCGGGGTCCCCTTCGTCCCTCGCACCAGCGTGGATGCATGGCTGGTGCACAGCGTGGCTGCCGGGAGCGCGGACGAGGCCCACGGGCTGCTCGGCGCCGCCGCCGCCTCGTCCACCGGAGGAGCCGGCGCCAGCGTGGACGGCGGCAGCCAGGCTGTGCAGGGGGGCGGCGGGGACCCCCGAGCGGCTCGGAGTGGCCCCTTGGACGCCGGGGAAGAGGAGAAGGCACCCGCGGAACCGACGGCTCAGGTGCCGGACGCTGGCGGATGTGCGAGCGAGGAGAATGGGGTACTAAGAGAAAAGCACGAAGCTGTGGATCATAGTTCCCAGCATGAGGAAAATGAAGAAAGGGTGTCAGCCCAGAAGGAGAACTCACTTCAGCAGAATGATGATGATGAAAACAAAATAGCAGAGAAACCTGACTGGGAGGCAGAAAAGACCACTGAATCTAGAAATGAGAGACATCTGAATGGGACAGATACTTCTTTCTCTCTGGAAGACTTATTCCAGTTGCTTTCATCACAGCCTGAAAATTCACTGGAGGGCATCTCATTGGGAGATATTCCTCTTCCAGGCAGTATCAGTGATGGCATGAATTCTTCAGCACATTATCATGTAAACTTCAGCCAGGCTATAAGTCAGGATGTGAATCTTCATGAGGCCATCTTGCTTTGTCCCAACAATACATTTAGAAGAGATCCAACAGCAAGGACTTCACAGTCACAAGAACCATTTCTGCAGTTAAATTCTCATACCACCAATCCTGAGCAAACCCTTCCTGGAACTAATTTGACAGGATTTCTTTCACCGGTTGACAATCATATGAGGAATCTAACAAGCCAAGACCTACTGTATGACCTTGACATAAATATATTTGATGAGATAAACTTAATGTCATTGGCCACAGAAGACAACTTTGATCCAATCGATGTTTCTCAGCTTTTTGATGAACCAGATTCTGATTCTGGCCTTTCTTTAGATTCAAGTCACAATAATACCTCTGTCATCAAGTCTAATTCCTCTCACTCTGTGTGTGATGAAGGTGCTATAGGTTATTGCACTGACCATGAATCTAGTTCCCATCATGACTTAGAAGGTGCTGTAGGTGGCTACTACCCAGAACCCAGTAAGCTTTGTCACTTGGATCAAAGTGATTCTGATTTCCATGGAGATCTTACATTTCAACACGTATTTCATAACCACACTTACCACTTACAGCCAACTGCACCAGAATCTACTTCTGAACCTTTTCCGTGGCCTGGGAAGTCACAGAAGATAAGGAGTAGATACCTTGAAGACACAGATAGAAACTTGAGCCGTGATGAACAGCGTGCTAAAGCTTTGCATATCCCTTTTTCTGTAGATGAAATTGTCGGCATGCCTGTTGATTCTTTCAATAGCATGTTAAGTAGATATTATCTGACAGACCTACAAGTCTCACTTATCCGTGACATCAGACGAAGAGGGAAAAATAAAGTTGCTGCGCAGAACTGTCGTAAACGCAAATTGGACATAATTTTGAATTTAGAAGATGATGTATGTAACTTGCAAGCAAAGAAGGAAACTCTTAAGAGAGAGCAAGCACAATGTAACAAAGCTATTAACATAATGAAACAGAAACTGCATGACCTTTATCATGATATTTTTAGTAGATTAAGAGATGACCAAGGTAGGCCAGTCAATCCCAACCACTATGCTCTCCAGTGTACCCATGATGGAAGTATCTTGATAGTACCCAAAGAACTGGTGGCCTCAGGCCACAAAAAGGAAACCCAAAAGGGAAAGAGAAAGTGAGAAGAAACTGAAGATGGACTCTATTATGTGAAGTAGTAATGTTCAGAAACTGATTATTTGGATCAGAAACCATTGAAACTGCTTCAAGAATTGTATCTTTAAGTACTGCTACTTGAATAACTCAGTTAACGCTGTTTTGAAGCTTACATGGACAAATGTTTAGGACTTCAAGATCACACTTGTGGGCAATCTGGGGGAGCCACAACTTTTCATGAAGTGCATTGTATACAAAATTCATAGTTATGTCCAAAGAATAGGTTAACATGAAAACCCAGTAAGACTTTCCATCTTGGCAGCCATCCTTTTTAAGAGTAAGTTGGTTACTTCAAAAAGAGCAAACACTGGGGATCAAATTATTTTAAGAGGTATTTCAGTTTTAAATGCAAAATAGCCTTATTTTCATTTAGTTTGTTAGCACTATAGTGAGCTTTTCAAACACTATTTTAATCTTTATATTTAACTTATAAATTTTGCTTTCTATGGAAATAAATTTTGTATTTGTATTAAAAATTAACTTTTCCCTTTTATACAGAATCTGAACCAAATTTACCTTACTTTCCTTCCAAAATATCCACATTCAGGAATATAGGTGAATAACAAATAAGGCAGCATAGCAAACTGCTCAGACTCAAGCCAAATTGAGGTCAACATAGTATGCCAAATCCATAGTAAGGCAAATCCACCCCCCTACCCCAATACTTAACACACAGAATACTATGTGATATAGAATGCACTGAAGACCTACGGTCACTGGTAGTTTGAGCCACAGGCCTTCCTCATGTAACCAGAGACAGAATGGGCTACTTGCAAAAACGTAACTCCTTGTGTGTATATTAAATCCATAAAATCTCTGGCAGTAAAGCCAGCCTGAAGGGATGGCCTCACCATCTTAGAATACTGAGATCTCACCAGAACACTGTAAGCCATATAAACAGTAGGGAAAGAGTCAGCAACAGTGAAACCATCTGTTTAAAATGGGCAAAAGCGATTAAGGGAAAAAAAACAGGTGAATTTGAAAATAAACCAGGGTAAGGTAAATTCTAGAAATAATAGCATTTGAAATGAAAACCTCACTTAAGTTCACTAGAACAGTAAACAGGAGATTGCTGAATTTTTTGAAGACAGCAATGACCTCACCTAGATGACTCAAGTTTGGGGAACATCAAGATTTTGACGGGTACTATAATGCTTAATATGTCCAAATTTTCAAAATGAAGTTTCTCAGATATTATTTCTGCCATAGGAGCTACAGTGTAGAGTATCACATAAGTATCTTGGGCTAGAGAAATGCAGTTTATATATACCGTTGGATTTTTATAATAAAGTTTCCCAAGACCTGTTATTTTGCCAGAAA

Publications

PMID - Link Title