Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SRP14P3
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:49795297-49795978  UCSC
Coordinates (T2T) chr17:50658401-50659082  UCSC
Coordinates (hg19) chr17:47872659-47873340  UCSC
Strand +
Parental Sequence NM_003134.6
Parental seq. overlap 623 bp
Parental seq. overlap (%) 55%
Genomic Region Intragenic (KAT7)
Retrocopy Summary SRP14P3, located on chr17:49795297-49795978, is a retrocopy of the parental gene SRP14. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SRP14
Full Name signal recognition particle 14
Also known as ALURBP
Coordinate chr15:40035690-40039202
Strand -
Gene summary Enables RNA binding activity. Involved in protein targeting to ER. Located in nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SRP14P4
Bonobo Pan paniscus SRP14P4
Gorilla Gorilla gorilla SRP14P2
Orangutan Pongo abelii SRP14P4
Green monkey Chlorocebus sabaeus SRP14P3
Crab-eating macaque Macaca fascicularis SRP14P6
Rhesus Macaca mulatta SRP14P6
Baboon Papio anubis SRP14P4
Golden snub-nosed monkey Rhinopithecus roxellana SRP14P4
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SRP14P3
GACTGCTAGGGGCTTACACGGAGGGAATTGAGCCAGCATCACCACGATGGTGTTGTTGGAGAGTGAGCAGTTCCTGACGGAGCTGACCAGACTTTTCCAGAAGTGCTGGACATCGGGCAGCATCTATATCACCTTGAAGAAGTATGGTGGTGGAACCAAACCCGTTCCAAAGAAAGGTTCTGTGGAGGGCTTTGAGCCCTCAGACAAGTGTCTGTTAAGAGCTATCGATGGGAAAAAGAAGGTCAGCACTGTGGTGAGCTCCAACCAAGTGAATAAGTTTCAGATGGCTTATTCAAACCTACCGAGTGCTAACATGGATGGGCTGAAGAAAAGGGACAAAAAGAACAAAAGTAAGAAGACCAAAGCAGCAGCACAGTAAAGGGCACAAATTTCCTGCTTTCACCAATTAACCACTGAATTGTTATTTTTTCCTTTGGTTTTTACTTTTGGCCACATAGCTAGGTTTCTGGTTCCCCTACACTAGGTGTTTTCACATAAGATGTAGGGTCCTTTTGCAAAGAATAGTTGCAATGTTTATAGGGCAGTTGTGGTAAGAATCTAGTTTATTTTACATTTGGCTAATTGGTCTGTACTGCATGGTTATATACTCCTGGATTATAGATTAAAAGTCTCTGTAGTCATCTCTGTGAAGAGCAAGCTATGATTAAACATGTCTCTTTAT
>NM_003134.6
AGGCCGAACTTCCGGCTCTCACTGCTAGGGGCTTAAGCGGAGGGAGTCGAGCCAGCGTCGCCGCGATGGTGTTGTTGGAGAGCGAGCAGTTCCTGACGGAGCTGACCAGACTTTTCCAGAAGTGCCGGACGTCGGGCAGCGTCTATATCACCTTGAAGAAGTATGACGGTCGAACCAAACCCATTCCAAAGAAGGGTACTGTGGAGGGCTTTGAGCCCGCAGACAACAAGTGTCTGTTAAGAGCTACCGATGGGAAGAAGAAGATCAGCACTGTGGTGAGCTCCAAGGAAGTGAATAAGTTTCAGATGGCTTATTCAAACCTCCTTAGAGCTAACATGGATGGGCTGAAGAAGAGAGACAAAAAGAACAAAACTAAGAAGACCAAagcagcagcagcagcagcagcagcagcacctgccgcagcagcaacagcaccaacaacagcagcaacaacagcagcaacagcagcaCAGTAAAGGGCATACATTTCCTGCTTTCACCAATTAACCACTGAATTGCTATTTTTTCCTTTTGGCCAGATAGCTAGGTTTCTGGTTCCCCCACAGTAGGTGTTTTCACATAAGATTAGGGTCCTTTTGGAAAGAATAGTTGCAGTGTTTATAGGATAGTTGTGGTAAGAATCTAGTTTATTTTGCATTTGGCTAATTGGTCTGTGCTGCATGGTTATATACTCCTGGATTATAGATTAAAAGTCTCTGTAGACATCTCTGTGAAGAGCAAGCTATCATTAAACATGTCTGTTTATCAGCACTGTCTCTTTATTCCTTTCCCAACCCATTTTAATAGTTCTGGCAATAACTACTAAATCTAGAATGATGTGATTAATGAATAGGCTTTAGCTCTATAATATCTTCTAGGTTATTAGAATTGAAACCTGACAGTTTTATAAAAAGTCATGTTATCTCATGAGCTGCTTCCCACCTGGCTGTATAATTTTATCATCATGGTTCCCCAGTTTCGATGAGTTCTCACAGTCAAATGAGAGTTTGTTTAACCACCTTAGGAGAAACATACTACAAAGTCATCAAGAATAAAGGTTCCAAAGTAATTATGATTTTTGGTTTCTTTATGCCCTTTGGTTTGGATATTTTCATGTGC

Publications

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