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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name S100A10P1
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:50797253-50797641  UCSC
Coordinates (T2T) chr17:51664390-51664778  UCSC
Coordinates (hg19) chr17:48874614-48875002  UCSC
Strand -
Parental Sequence NM_002966.3
Parental seq. overlap 329 bp
Parental seq. overlap (%) 48.8%
Genomic Region Intergenic
Retrocopy Summary S100A10P1, located on chr17:50797253-50797641, is a retrocopy of the parental gene S100A10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name S100A10
Full Name S100 calcium binding protein A10
Also known as 42C|ANX2L|ANX2LG|CAL1L|CLP11|Ca[1]|GP11|P11|p10
Coordinate chr1:151982915-151993859
Strand -
Gene summary The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes S100A10P1
Bonobo Pan paniscus S100A10P1
Gorilla Gorilla gorilla S100A10P1
Orangutan Pongo abelii S100A10P2
Gibbon Nomascus leucogenys S100A10P2
Green monkey Chlorocebus sabaeus S100A10P1
Crab-eating macaque Macaca fascicularis S100A10P1
Rhesus Macaca mulatta S100A10P1
Baboon Papio anubis S100A10P2
Golden snub-nosed monkey Rhinopithecus roxellana S100A10P4
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>S100A10P1
AATGGAACACACCATGGAAACCGTGTTGTTTACGTTTCACAGATTTGCCGGGGATAAAGGCTACTTAATGAAGGAGGGCCTGAAAGTACTCATGGGAAAGGAGTTCCTTGGATTTTTGGAGAATCAAAAAGACCCTCTGGCTGCAGACATAACAATGAAGGACATGGACCAGTGCCAAGACAGCACACTGAACTTCCAGAACTTGTTTTCACTCACTGCGGGGCTCACCACTGTGGACAACAACTATTTTGTAGTACCTATGAAGCAGAAGGGAACGAAGCAGGCAGAACTAAGCAATTACTCAGCCCTGTGAGAGTTCTCCCAAAGAGTCGCTATAGGAACCTGCCCACAGCTTCCCCCTGTAGAAGGCTTTCATGAGCAGACCAGGG
>NM_002966.3
ACCCACCCGCCGCACGTACTAAGGAAGGCGCACAGCCCGCCGCGCTCGCCTCTCCGCCCCGCGTCCAGCTCGCCCAGCTCGCCCAGCGTCCGCCGCGCCTCGGCCAAGGCTTCAACGGACCACACCAAAATGCCATCTCAAATGGAACACGCCATGGAAACCATGATGTTTACATTTCACAAATTCGCTGGGGATAAAGGCTACTTAACAAAGGAGGACCTGAGAGTACTCATGGAAAAGGAGTTCCCTGGATTTTTGGAAAATCAAAAAGACCCTCTGGCTGTGGACAAAATAATGAAGGACCTGGACCAGTGTAGAGATGGCAAAGTGGGCTTCCAGAGCTTCTTTTCCCTAATTGCGGGCCTCACCATTGCATGCAATGACTATTTTGTAGTACACATGAAGCAGAAGGGAAAGAAGTAGGCAGAAATGAGCAGTTCGCTCCTCCCTGATAAGAGTTGTCCCAAAGGGTCGCTTAAGGAATCTGCCCCACAGCTTCCCCCATAGAAGGATTTCATGAGCAGATCAGGACACTTAGCAAATGTAAAAATAAAATCTAACTCTCATTTGACAAGCAGAGAAAGAAAAGTTAAATACCAGATAAGCTTTTGATTTTTGTATTGTTTGCATCCCCTTGCCCTCAATAAATAAAGTTCTTTTTTAGTTCCAAA

Publications

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