Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GNL3P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:75521570-75522081  UCSC
Coordinates (T2T) chr1:75358513-75359024  UCSC
Coordinates (hg19) chr1:75987255-75987766  UCSC
Strand +
Parental Sequence NM_206825.2
Parental seq. overlap 410 bp
Parental seq. overlap (%) 20.1%
Genomic Region Intragenic (SLC44A5)
Retrocopy Summary GNL3P1, located on chr1:75521570-75522081, is a retrocopy of the parental gene GNL3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GNL3
Full Name G protein nucleolar 3
Also known as C77032|E2IG3|NNP47|NS
Coordinate chr3:52685920-52694497
Strand +
Gene summary The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GNL3P1
Bonobo Pan paniscus GNL3P1
Gorilla Gorilla gorilla GNL3P1
Orangutan Pongo abelii GNL3P1
Gibbon Nomascus leucogenys GNL3P1
Golden snub-nosed monkey Rhinopithecus roxellana GNL3P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GNL3P1
AATGGAGGCTCCCAGTGTCATCTGGTCCCAGGCTGATGCTTGACAGGTAAAACTGGAATTTGCTGCCCCAAACTATAGTAATTCTCCGGAATTTTTTGCTTTGCTTGTGCAGAGAAAAGGAATACACCAAAAAGGTAGAAGCTCAAATATAGGAGGTGCTGCCGTACTGCTGTGGTCTGAGTGAATAGGTGCCCCTTTAAGTTACAAATGTCACTTGCCTACATCCTGGACTCCTCCACATTCTAATGAGAGTATTGGGACAGACATCACATGAGGCTTAATCTGGAAGAACTAGAAAAAAAACAATGCACGCAGTGTACAAGTCATCAGGGGCCCTCGTTTAGCCAGCAGCATCCTTTTCTGGTCTTTGGGTTTCACAAAATAATAGAGGAAAAAGACATACTCTGAAGAAATCCCAAAACAGGAAGAGAAGGAGCAGGAGGAGAGGAAGCACAACACTCACAGTGCCCAGGAAAGTGGTGATGGTGAAGAAGTTGTTTAAAAGAGCTCAG
>NM_206825.2
AGTTCACACGTGGCGCCAGCGGAGGCAGGTTGATGTGTTTGTGCTTCCTTCTACAGCCAATATGAAAAGGCCTAGTAAGTGGGGTCGGGAGGCGGGCGTGGAGGGACCCACGTCTGGAAGTTGCTGCAGCCACCACGACGCTCTTCTACGGCTACGGCTTTGTCTCTGCTGAGTTAAAGAAAGCAAGTAAACGCATGACCTGCCATAAGCGGTATAAAATCCAAAAAAAGGTTCGAGAACATCATCGAAAATTAAGAAAGGAGGCTAAAAAGCGGGGTCACAAGAAGCCTAGGAAAGACCCAGGAGTTCCAAACAGTGCTCCCTTTAAGGAGGCTCTTCTTAGGGAAGCTGAGCTAAGGAAACAGAGGCTTGAAGAACTAAAACAGCAGCAGAAACTTGACAGGCAGAAGGAACTAGAAAAGAAAAGAAAACTTGAAACTAATCCTGATATTAAGCCATCAAATGTGGAACCTATGGAAAAGGAGTTTGGGCTTTGCAAAACTGAGAACAAAGCCAAGTCGGGCAAACAGAATTCAAAGAAGCTGTACTGCCAAGAACTTAAAAAGGTGATTGAAGCCTCCGATGTTGTCCTAGAGGTGTTGGATGCCAGAGATCCTCTTGGTTGCAGATGTCCTCAGGTAGAAGAGGCCATTGTCCAGAGTGGACAGAAAAAGCTGGTACTTATATTAAATAAATCAGATCTGGTACCAAAGGAGAATTTGGAGAGCTGGCTAAATTATTTGAAGAAAGAATTGCCAACAGTGGTGTTCAGAGCCTCAACAAAACCAAAGGATAAAGGGAAGATAACCAAGCGTGTGAAGGCAAAGAAGAATGCTGCTCCATTCAGAAGTGAAGTCTGCTTTGGGAAAGAGGGCCTTTGGAAACTTCTTGGAGGTTTTCAGGAAACTTGCAGCAAAGCCATTCGGGTTGGAGTAATTGGTTTCCCAAATGTGGGGAAAAGCAGCATTATCAATAGCTTAAAACAAGAACAGATGTGTAATGTTGGTGTATCCATGGGGCTTACAAGGAGCATGCAAGTTGTCCCCTTGGACAAACAGATCACAATCATAGATAGTCCGAGCTTCATCGTATCTCCACTTAATTCCTCCTCTGCGCTTGCTCTGCGAAGTCCAGCAAGTATTGAAGTAGTAAAACCGATGGAGGCTGCCAGTGCCATCCTTTCCCAGGCTGATGCTCGACAGGTAGTACTGAAATATACTGTCCCAGGCTACAGGAATTCTCTGGAATTTTTTACTGTGCTTGCTCAGAGAAGAGGTATGCACCAAAAAGGTGGAATCCCAAATGTTGAAGGTGCTGCCAAACTGCTGTGGTCTGAGTGGACAGGTGCCTCATTAGCTTACTATTGCCATCCCCCTACATCTTGGACTCCTCCTCCATATTTTAATGAGAGTATTGTGGTAGACATGAAAAGCGGCTTCAATCTGGAAGAACTGGAAAAGAACAATGCACAGAGCATAAGAGCCATCAAGGGCCCTCATTTGGCCAATAGCATCCTTTTCCAGTCTTCCGGTCTGACAAATGGAATAATAGAAGAAAAGGACATACATGAAGAATTGCCAAAACGGAAAGAAAGGAAGCAGGAGGAGAGGGAGGATGACAAAGACAGTGACCAGGAAACTGTTGATGAAGAAGTTGATGAAAACAGCTCAGGCATGTTTGCTGCAGAAGAGACAGGGGAGGCACTGTCTGAGGAGACTACAGCAGGTGAACAGTCTACAAGGTCTTTTATCTTGGATAAAATCATTGAAGAGGATGATGCTTATGACTTCAGTACAGATTATGTGTAACAGAACAATGGCTTTTTATGATTTTTTTTTTAACATTTTAAGCAGACTGCTAAACTGTTCTCTGTATAAGTTATGGTATGCATGAGCTGTGTAAATTTTGTGAATATGTATTATATTAAAACCAGGCAACTTGGAATCCCTAAATTCTGTAAAAAGACAATTCATCTCATTGTGAGTGGAAGTAGTTATCTGGAATAAAAAAAGAAGATACCTATTGAAAAA

Publications

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