Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DLSTP1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:75742022-75744782  UCSC
Coordinates (T2T) chr1:75578685-75581445  UCSC
Coordinates (hg19) chr1:76207707-76210467  UCSC
Strand -
Parental Sequence NM_001933.5
Parental seq. overlap 2657 bp
Parental seq. overlap (%) 94.2%
Genomic Region Intragenic (ACADM)
Retrocopy Summary DLSTP1, located on chr1:75742022-75744782, is a retrocopy of the parental gene DLST. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DLST
Full Name dihydrolipoamide S-succinyltransferase
Also known as DLTS|KGD2|PGL7
Coordinate chr14:74881916-74903743
Strand +
Gene summary This gene encodes a mitochondrial protein that belongs to the 2-oxoacid dehydrogenase family. This protein is one of the three components (the E2 component) of the 2-oxoglutarate dehydrogenase complex that catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DLSTP1
Bonobo Pan paniscus DLSTP1
Gorilla Gorilla gorilla DLSTP1
Orangutan Pongo abelii DLSTP1
Gibbon Nomascus leucogenys DLSTP1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DLSTP1
CCGCCGTGATGCTGTCCCGGTCCCACTGTGTCCCGGGCGTTCAGCCACTCGCTCTCTGCCTTCCAGAAGGGGAACTGCCCTCTAGGGAGACATTCCCTGCCTGGGGTCTCCTTATGCCAGGGACCAGGTTACCCTAACAGCAGGAAGGTTGTCATTAACAACAGTGTCTTCAGTGTTCGCTTCTTCAGAACTACAACTGTATGCAAGTATGACTTGGTTACAGTCAAAACCCCAGCGTTTGCAGAACCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGCTGTTGGAGACACAGTTGCAGAAGATGAAGTGGTTTGTGAGATTGAAACTGACAAGACATTGGTGCAGGTTCCATCACCAGCAAATGGCATGATTGAAGCTCTTTTCGTACCTGATGGGGGAAAAGTCGAAGGAGGCACTCCGCTTTTCACACTCAGGAAAACTGGTGCTGCTCCTGCTAAGGCCAAGCCGGCTGAAGCTCCTGCTGCTGCAGCCCCAAAAGCAGAACCTATAGCAGCGGCAGTTCCTCCCCATGCAGCACCCATACCCACTCGATGCCACCAGTGCCCTCGCCCTCACAACCTCCTTCTAGCAAACCTGTGTCTGCAGTAAAACCCACTGCTGTCCCACCACTAGCTGAGCCAGGAGCTGGCAAAGGTCTGCATTCAGAACATCAGGAGAAAATGAACAGGATGCGGCAGTGCATTGCTCAGCGTCTGAAGGAGGCCCAGAATACATGTGCCAATGCTGACAATTTTTAATGAGATTGATGTGAGTAACATCCAGAAGATGAGGGCTCGGCACAAAGAGGCTTTTTTGAAGAAACATAACCTCAAACTAGGCTTCATGTCGGCATCTGTGAAGGCCTCAGCCTTTGCCTTGCAGGAACAGCCTGTTGTAAACGCAGTGATTGATGATATAACCAAAGAGGTGGTATATAGGGATTATATTGACATCAGTGTTGCAGTGGCCACCCCACAGGGTCTGGTGGTTCCAGTCATCAGGAATGTGGAAGCTATGAATTATGCAGATATTGAACAGACCATCACTGAACTGGGAGAGAAGGCCCGAAAGAATGAATTTGCCATTGAAGATATGGATGGTGGTACCTTCACCATTAGCAATGGAGGTGTTTTTGGCTCACTCTTTGAACACCCATTATCAACCCCCCTGTCTGCCATCCTGGGGATGCATGGCATCTTTGACAAGCCAGTGGCTATAGGAGGCAAGGTAGAGGTGCAGCCCATGATGTACGTGGCACTGACCTATGATCACCGGCTGATTGATGGCAGAGAGGCTGTGACTTTCCTCCGCAAAATCAAGGCAGCGGTAGAGGATCCCAGAGTCCTCCTCTTTGATCTTTAGGAGGAACCCACACACCCTACAAATTGATCATGCAGGAACTGAAAACCAGTCTTCTCCCTGTCCCCTCATGGGTCCCAGGTTAGCCTGGTGACAGGCACATGCTGTTGGCCTCAAGCAAGGAAGCAGAGCACTATGTAACCAGCAGTCACAGCTTTTTTCTTGGTGTTCCTGCCTGGCTCTCTCCCTCTCTGCACCTGTCTCATACCCTCGAATATCTTAATTCCTTAGGCTTGAGAGAGAGAGCCTTAATGGATGCTCATTCATATTCCTGCCTTTCTTCCATCAGCTCTCTGCAAAGATGATTTTGCTTCTCCCTAGTGCTGGTATACTATAGAGAAACCCCCGAGGACCATGTGATTAAGTTCCTATCTTTTGAAAGTTTGTTCTGCAGAGACATCTAGGAGGATGCTGTGCCTCCCAAGCTCAGAGCAGCCTCTGTCCTGGCTGTGCACATTCTCGATTCCACTTGTATGGAGGGATTGAACACAGGCAAAGAGGTGCTGCTTTCCTTCTTCAATGGCACCTTCATTCTCCATTGTCATTGACTTCAAGATGCCTCTTCTACCTCTACCAGGAAGCACAGGCCAGGGGATCTGGGTGTGTGAATGGGAGGAGAGAGCAGAGGTTCCCTGAGGTCACGTGTTGTAATCATCATAGAAGGAGAGCCCAGGTCTGCCCTCACGCTCTCCATCATAGGCTCACACCAAGAAGACTCATCTTGGCACAATCTCACACAGCTGGGGCTGTAGCAACCCTTTCCTGGTTGCTGGGCCTCATTCTAGCACCTTGTTCTTACTTAGAGCAGATTCTAGCACATCATGGCAGTGGAACCAAGCGTAGTCCCGAAGAAGGGCCAGAGCCTGGTAGAGATTAGGGAAGGGAGGTCTCCTCTAGACTCAGATTGCCTTGAGCTTTTCAAGTAAGTTGCTGTAAGCCCGTGGGCTGAGGAGGCAGTTCTTGTTCCTTCCTGCGTTATAGTGGGGCCTTGTCTCTTCCTCTGCAGGACACAGATTTGGAGGACGTGGACTGGGGTAGGAAACCACCCTGAGGGTGTTAGTAGATAGTGGTGTAATGGATGAGGTCATTTCTAAGATGTGTTGCCGGTGGATCTGGGCACAATCATTGGAATTCCTTGGAGCTACTGGGATTCATGGCTTTGTATCCAACTGCATCCAGGCCTGAGGCTGCTGACATTTGACACTAGGGCCAGTAGAGAGTGCCTTTTTGTATCTTGAGCCAAGAAGTGAGGCCTGGGGGTGGGGAGGGGGGAAGGGGTGGGAGCCAATACTGAGTGCCTGCAGCATCTACTACTCTGTCTTCACTATTCAGAACTTGTAACTAAAGTATTTAAAGAAACTGATTTTAAATGCAAATTAAAGGGCAGATGTTCTCAAAA
>NM_001933.5
ATATCCGGTGTCCGCCCGCCCTCGGCTCCTCCGCCGTGATGCTGTCCCGATCCCGCTGTGTGTCTCGGGCGTTCAGCCGCTCGCTCTCCGCCTTCCAGAAGGGGAACTGCCCTCTAGGGAGACGTTCCCTGCCTGGGGTCTCCTTATGCCAGGGACCAGGTTACCCTAACAGCAGGAAGGTTGTCATTAACAACAGTGTCTTCAGTGTTCGCTTTTTCAGAACTACAGCTGTATGCAAGGATGACTTGGTTACAGTCAAAACCCCAGCGTTTGCAGAATCTGTCACAGAGGGAGATGTCAGGTGGGAGAAAGCTGTTGGAGACACAGTTGCAGAAGATGAAGTGGTTTGTGAGATTGAAACTGACAAGACATCTGTGCAGGTTCCATCACCAGCAAATGGCGTGATTGAAGCTCTTTTGGTACCTGATGGGGGAAAAGTCGAAGGAGGCACTCCACTTTTCACACTCAGGAAAACTGGTGCTGCTCCTGCTAAGGCCAAGCCGGCTGAAGCTCCTGCTGCTGCAGCCCCAAAAGCAGAACCTACAGCAGCGGCAGTTCCTCCCCCTGCAGCACCCATACCCACTCAGATGCCACCGGTGCCCTCGCCCTCACAGCCTCCTTCTGGCAAACCTGTGTCTGCAGTAAAACCCACTGTTGCCCCACCACTAGCTGAGCCAGGAGCTGGCAAAGGTCTGCGTTCAGAACATCGGGAGAAAATGAACAGGATGCGGCAGCGCATTGCTCAGCGTCTGAAGGAGGCCCAGAATACATGTGCAATGCTGACAACTTTTAATGAGATTGACATGAGTAACATCCAGGAGATGAGGGCTCGGCACAAAGAGGCTTTTTTGAAGAAACATAACCTCAAACTAGGCTTCATGTCGGCATTTGTGAAGGCCTCAGCCTTTGCCTTGCAGGAACAGCCTGTTGTAAATGCAGTGATTGACGACACAACCAAAGAGGTGGTGTATAGGGATTATATTGACATCAGTGTTGCAGTGGCCACCCCACGGGGTCTGGTGGTTCCAGTCATCAGGAATGTGGAAGCTATGAATTTTGCAGATATTGAACGGACCATCACTGAACTGGGAGAGAAGGCCCGAAAGAATGAACTTGCCATTGAAGATATGGATGGCGGTACCTTCACCATTAGCAATGGAGGCGTTTTTGGCTCGCTCTTTGGAACACCCATTATCAACCCCCCTCAGTCTGCCATCCTGGGGATGCATGGCATCTTTGACAGGCCAGTGGCTATAGGAGGCAAGGTAGAGGTGCGGCCCATGATGTACGTGGCACTGACCTATGATCACCGGCTGATTGATGGCAGAGAGGCTGTGACTTTCCTCCGCAAAATCAAGGCAGCGGTAGAGGATCCCAGAGTCCTCCTCCTGGATCTTTAGGAGGAACCCACACACCCTACAAGTTGATCATGCAGGAACTGAAAACCAGTCTTCTCCCTGTCCCCTCATGGGTCCCGGGTTAGCCTGGTGACAGGCAGACACATGCTGTTGGCCTCAAGCAAGGAAGCAGAGCACTGTGTAACCAGCAGTCACAGGTCTTTTCTTGGCGTTCCTGCCAGGCTCTCCCTCTCTGCACCTGTCTCATAGCCTCGAATATCTTAATTCCTTAGGCTTAAGAGAGAGAGCCTTAATGGATGCTCATTCATATTCCTGCCTTTCTTCCATCAGCTCTCTGCAAAGATGATTTTGCTTTTCCCTAGTGCTGGTATACTATAGAGAAACCCCTGGGGACCATGTGATTAAGTTCCTATCTTTTGAAAGTTTGTTCTGCAGAGACTTCTAGGAGGATGCTGTGCCTCCCAAGCTCAGAGCAGCCTCTGTCCTGGCTGTGCACATTCTCCCTTGATTCCACTTGTGTGGAGGGATTGAACACAGGCAAAGAGGTGCTGCTTTGCTTCTTCAATGGCACCTTCATTCTCCGTTGTCATTGACTTCAAGATGCCTCTTCTACCTCTTCCAGGAAGCACAGGCCAGGGGATCTGGGTGTGTGAGTGGGAGGAGAGGGCAGAGGTCCCCTGAGGTCATGCATTGTAATCATCATAGAAGGAGAGCCCAGGCCTGCCCTCACGCTCTCCATCATAGGCTGACACCAAGAAGACTCGTCTTGGCACAATCTCACACAGCTGGGGCTGTAGCAACCCTTTCCAACCCCTTTGCTGGTTGCTGGGCCTCATTCTAGCACCTTGTTCTTAGAGCAGATTCTAGCACATCATGGCAGTGGGACCAAGCGTGGTCCCGAGGAAGGGCCAGAGCCTGGTAGAGACTAGGGAAGGGAGGTCTCCTCTAGACTGACTCACATTGCCTTGAGCTTTTCAGTTAAGTTGCTGTAAGCACCTGGGCTGAGGAGGCAGTTTTTGTTCCTTCCTGCGTTATAGCGGGGCCTTGTCTCTTCCTCTGCAGGACACAGATCTGGAGGACGTGGACTGGGGTAGGAAACCACCCTGAGGGTGTTAGTACCTAGTGGTGAAACGGATGAGGTCATTTCTAAGGTGTGTTGCCCGTGGATCTGGGCACAATCATTGGAATTCCTTGGAGCCACTGGGATTCATGGCTTTGTATCCAACTGCATCCAGGCCTGAGGCTGCTGACGTTTGACACCAGGGCCAGTAGAGAGTGCCCTTTTGTATCTTAAGCCAAGAAGTGAGGCCTGGGGGTGGGGGAGGGGGGAAGGGGTGGGAGCCAATACTGAGTGCCTGCAGCATCTACTACTCTGTCTTCACTATTCAGAACTTGTAACTAAAGTATTTAAAGAAACTGATTTTAAATGCAAATTAAAGGGCAGATATTCTCAAA

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