Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AP1S2P2
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:60099302-60102785  UCSC
Coordinates (T2T) chr17:60968257-60971740  UCSC
Coordinates (hg19) chr17:58176663-58180146  UCSC
Strand -
Parental Sequence NM_001369007.1
Parental seq. overlap 2067 bp
Parental seq. overlap (%) 43.8%
Genomic Region Intergenic
Retrocopy Summary AP1S2P2, located on chr17:60099302-60102785, is a retrocopy of the parental gene AP1S2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AP1S2
Full Name adaptor related protein complex 1 subunit sigma 2
Also known as DC22|MRX59|MRXS21|MRXS5|MRXSF|PGS|SIGMA1B
Coordinate chrX:15825806-15854813
Strand -
Gene summary Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AP1S2P4
Bonobo Pan paniscus AP1S2P4
Gorilla Gorilla gorilla AP1S2P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AP1S2P2
ACTCAAATCTGGAGAGTTTGTTAAAATCTGTCTTGAGGATTTTTAAAAAAGTAATATCCTCAGTCTCAGTCAAATTCTTTGGATTTTTTGCTTTTGTAGGTATAAGTAAACAGTTAAAAACCTTCATTGCTACTTAAAATACCAGATGAGTGACTACTTTTCCAGTTTTTTTGGGAAAGATTTTTCTCTAGTTTCTTTAGTTTATGTAATACAAATGTACTAATGAATTTAAACACTGGTGGAAGGGAAATATTCTAATTGAATTTTTGGTCAACTCAGTATTGACCAGATGACTTACACTGAAAATCTTTTCATAATATTAGTAGTAAATATAGTGTTTTAGGATTTTGTAAAATTTCTGGAGGATGTCTGTCATCATTTTGAACACTGTATGTAGTAAAGTTAGAAAAAAATGAATCTAAAGTCTTGGGCATTGTTTAGAAGTTAAATATTCAGCCTTAAACCAAAGAAGGAAAGCAAACAGAAACTTAAGTTTTAGTTATCTTTACTGTGAACTAAATGTTCTAGAAATCTGATTGTGTCTGTGTCAGTTTGTATACTGTGTGTAAGAATATATGCATTTCTTTTGTAGCCACGTCATGAATATTTTAATGTCCCTGTGTACTAAATGACTACTCATCGAGTATGCAGAATTTCACAGAGGAAATAGAATGCTGATATACATATGAAAGAAAATATCCTCAGCATGGTGATTTATTGTCTTGTATAATAATAGTAGAACATTTTAGAACTAGTACTTTTATGATTGTATTTTTTTCCTGTTCACATTCCAAACTTTTCTGTATTTTCATTCTATATGTGATCTTGATACAGCTCATTCCTCTCTGCAACTGATTTAATCTCATCTTGATAAAATATGACCTAGAAGTGTTTTGAGTAATATTAAATCTTAAACATATACATATTATTAATGAACCATCTGTGATTTATCTTATAAGAGGAAAACATGACAATCATTAAAATGTTTACCAAAGAAAATATAGCTGAAGTGCTAGGTCAAAATAAGCAGTGCCATAATATATAGTGTGGTTTGGTCTTCAAATATTGAGGTTAAAAAAAGAAACTATTTTGTGTGATTATCTTACAATCTGTATGAGCTAATGTGTTCTAATGTATCACATAAAAGTATATGTGAAAATATTACAAGAAACTAAAATTAATTTGTACCATTATATAATATTTAAGGTTAAAACATTCAGTATTAAGAAATTTTGTAGTGCCACATTTATTGAATCACATTTGTGCTATATAATAATATCAAACAATCCCTTTAAGAACTTATTAGAGAGCTATGTCTGAAGTCTGTTCTGCAGTATCTGTTGCTGAATAATAACTCTTTCAAAGCATTAATGCTGAGTTTATATAGTTCAAAAATTCTAATATTCATTCAGTTTTAATACCTAAATACTTATATTTTACTAGTGATGGCATTCTAATATATTAAGTCCTCATTTAAATACTTAATACTTTGTTAACTGTGGCATTATATTTCTGAATTTTAAAACCTTTAATATTGGTAACTATTGCATATTCTTTTAATAAAACATGCAGCATATTTTTTTATAAAAGGAAAAGAATTCATTGTTTATATATAGACAGCATAAAGCCTAAGTTAAGTAAGTTATTAAACAATAACTTCACAAGATGTTCAAATCGATTTACCACTGAAAGAAGATCTATGAAAATGTGTTTTGACCAAACTTAGTATTAGGCAGGTACACAGATAAGATTTTCCATTCTTAACATTCTCACTGTAATGCACTACATTTGAAGCACCTGGATGTGCTATCAGGTGGGAAATTTAGCATTATATATTGGAAGCATTGAGAAACATTGGTCTTTCATTTCTATTTTTCCCCTCCTTTCCTCCTCCTGCCCCATAATATATTATTCATCTGGTTTTAATGCTACATAAATATGCATTGTCTCATGTCTGTTTGCGTTGGATGCCTTGTGCTAAGCTGTAACAAAATGTTGCTTCTTTTGCTGTCTGTATACAGCTGCTTGCTTTAAATTAGTAGATTCTGAAATAGCTTTCCTTGCATGTCTAAAATAAAAGTATTGCATAGCCATGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAAAAATGGTATGTCCCACTATCGGACAAAGAGAAGAAAAAGATCACAAGAGAACTTGTTCAGACCGTTTTAGCACGGAAACCTAAAATGTGCAGCTTCCTTGAGTGGCGAGATCTGAAGATTGTTTACAAAAGATATGCTAGTCTGTATTTTTGCTGTGCTATTGAGGATCAGGACAATGAACTAATTACCCTGGAAATAATTCATCGTTATGTGGAATTACTTGACAAGTATTTCGGCAGTGTCTGTGAACTAGATATCATCTTTAATTTTGAGAAGGCTTATTTTATTTTGGATGAGTTTCTTTTGGGAGGGGAAGTTCAGGAAACATCCAAGAAAAATGTCCTTAAAGCAATTGAGCAGGCCGATCTACTGCAGGAGAAAACAGAGACTATGTATCACAGCAAGAGTTTCACTGGGTTTAAGAAAGCGTACTAGAATACCTGCTGGAGTACTGACACGCATCGAAATGTAGTAGGGTATATACATTCAGTTTGTAATGACAATTCTGTCAAGTTTGTTATTTATATTTTAGCATTACCTGAAAAGTCTAATTACATTAAATCCCAAGGGATAGTCCCAATTACTTCATTAAACTGGTATTTTCATAGGGAATTTTGCTTGGATAATGATCCATTATTGGGGCTTATAATTTATTTTTTACACAGAATATGGAAATAGCTTCAGAGGTTCATTGACAAAAAAGCATTCATTAAATACTGTGAATCACTAATGCCATTGATACAGAAGAATTTCCCTATGAAAATGAGAGCTTCTGTGAGAAAATGAAGTAGTTGGGAGTTTAATTTCTTACTAATATGATTTTAACTTGCTGCTTCATTCCACTATATTCTGAGTTGGGGGAAAAGGGCAGCTATCTCTTTAAAATATTTAGGAATTCTTTGAGGATTAAAATGTAACTGGCTTTTGTCCTCAGATACGTTTGTAATTAATGGTTGTGTAAGTTTAGGGATTTGTTAGATATTTTTCTTGGAACAGTTTACATGATTTTGTAGTTCAATATTTCAAAGTTTCAAATTGAATAAATATTAAAATGAGGATACTTTAAAGACACTCAAATAAGCAATTTTAAACTTGCTTTCTGGTGGGGATATATCCCCACAGCACCACGGCTTCTCTTCCTCAGCACGGCGACAGGGGCTTCCCCTTTg
>NM_001369007.1
ATGCCAGCCGGGTGTCCTCCCCACAGCACCACGGCTTCTCTTCCTCAGCACGGCGACAGGGGCTTCCCCTTcgccgccgccgccgccgccggccaagctccgccgcgcccgcggcccgcggccgccATGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAAAAATGGTATGTCCCACTATCAGACAAAGAGAAGAAAAAGATCACAAGAGAACTTGTTCAGACCGTTTTAGCACGGAAACCTAAAATGTGCAGCTTCCTTGAGTGGCGAGATCTGAAGATTGTTTACAAAAGATATGCTAGTCTGTATTTTTGCTGTGCTATTGAGGATCAGGACAATGAACTAATTACCCTGGAAATAATTCATCGTTATGTGGAATTACTTGACAAGTATTTCGGCAGTGTCTGTGAACTAGATATCATCTTTAATTTTGAGAAGGCTTATTTTATTTTGGATGAGTTTCTTTTGGGAGGGGAAGTTCAGGAAACATCCAAGAAAAATGTCCTTAAAGCAATTGAGCAGGCTGATCTACTGCAGGAGAAAACAGAGACTATGTATCACAGCAAGAGTTTCATTGGGTTTAAGAAAGCGTACTAGAATACGTGCTGGAGTACTGACATGCATCAAAATGTAGTAGGATATATAAATTCAGTTTGTAATGACAATTTTGTCAAGTTTGTTATTTATATTTTAGCATTACCTGAAAAGTCTAATTACATTAAATCCCAAGGGATAGTCCCAATTACTTCATTAAACTGGTATTTTCATAGGGAATTTTGCTTGGATAATGATCCATTATTGGGGCTTATAATTTATTTTTTACACAGAATATGGAAATAGCTTCAGAGGTTCATTGACAATAAAGCATTCATTAAATACTGTGAATCACTAATGCCATTGATACAGAAGAATTTCCCTATGAAAATGAGAGCTTCTGTGAGAAAATGAAGTAGTTGGGAGTTTAATTTCTTATTAATATGATTTTAACTTGCTGCTTCATTCCACTATATTCTGAGTTGGGGGAAAAGGGCAGCTATCTCTTTAAAATATTTAGGAATTCTTTGAGGATTAAAATGTAACTGGCTTTTGTCCTCAGATACGTTTGTAATTAATGGTTGTGTAAGTTTAGGGATTTGTTAGATATTTTTCTTGGAACAGTTTACATGATTTTGTAGTTCAACATTTCAAAGTTTCAACTTGAATAAATATTAAAATGAGGATACTTTAAAGACACTCAAATAAGCAATTTTAAACTTGCTTTCTGGTGGGGATATAatccctttgagagtctgaaggatgatgggctgtcaccccaggaaaatttgcacatcattttgtttctaatttcagggaactctcagagcccctagaagtccttctgtagacACTCAAATCTGGAGAGTTCGTTAAAATCTGTCTTGAGGATTTTTAAAAAAGTAATATCCTCAGTCTCAGTCAAATTCTTTGGATTTTTTGCTTTTGTAGGTATAAGTAAACGGTTAAAAACCTTCATTGCTACTTAAAATACCAGATGAGTGACTACTTTTCCAGTTTTTATTGGGAAAGATTTTTCTCTAGGTTCTTTAGTTTATGTAATACAAATGAACTAATGAATTTAAATACTGGTGGAAGGGGAATATTCTAATTGAATTTTTGGTCAACTCAGTATTGACCAGATGACTTACACTGAAAATCTTTTCATAATATTAGTAGTAAATATAGTGTTTTAGGATTTTGTAAAATTTCTGGAGGATGTCTGTCATCATTTTGAACACTGTATGTAGTAAAGTTAGAAAAAAATGAATCTAAAGTCTTGGGCATTGTTTAGAAGTTAAATATTCAGCCTTAAACCAAAGAATGAAAGCAAACAGAAACTTAAGTTTTAGTTATCTTTACTGTGAGCTAAATGTTCTAGAAATCTGATTGTGTCTGTGTCAGTTTGTATACTGTGTGTAAGAATATATGCATTTCTTTTGTAGCCACGTCATGAATATTTTAATGTCCCTGTGTACTAAATGACTACTCATCGAGTATGCAGAATTTCACAGAGGAAATAGAATGCTGATATACATATGAAAGAAAATATCCTCAGCATGGTGATTTATTGTCTTGTATAATAATAGTAGAACATTTTAGAACTAGTACTTTTATGATTGTATTTTTTTCCTGTTCACATTCCAAACTTTTCTGTTTTATTTTCATTCTATATGTGATCTTGATACAGCTCATTCCTTTCTGCAACTGATTTAATCTCATCTTGACAAAATATGACCTAGAAGTGTTTTGAGTAATATTAAATCTTAAACACATACATATTATTAATGAACCATCTGTGATTTATCTTATAAGAGGAAAACATGACAATCATTAAAATGTTTACCAAAGAAAATATAGCTGAAGTGCTAGGTCAAAATAAGCAGTGCCATAATATATAGTGTAGTTTGGTCTTCAAATATGGAGGTTAAAAAAAGAAACTATTTTGTGTGATTATCTTACAATCTGTATGAGCTAATGTGTTCTAATGTATCACATAAAAGTATATGTGAAAATATTACAAGAAACTAAAATTAATTTGTACCATTATATAATATTTAAGGTTAAAACATTCAGTATTAAGAAATTTTGTAGTGCCACATTTATTGAATCACATTTGTGCTATATAATAATATCAAACAATCCCTTTAAGAACTTATTAGAGAGCTATGTCTGAAGTCTGTTCTGCAATATCTGTTGCTGAATAATAACTCTTTCAAAGCATTAATGCTGAGTTTATATAGTTCAAAAATTCTAATATTCATTCAGTTTTAATACCTAAATACTTATATTTTACTAGTGATGGCATTCTAATATATTAAGTCCTCATTTAAATACTTGATACTTTGTTAACTGTGGCATTATATTTCTGAATTTTAAAACCTTTAATATTGGTAACTATTGCATATTCTTTTAATAAAACATGCAGCATATTTTTTTATAAAAGGAAAAGAATTCATTGTTTATATCTAGAGAGCATAAAGCCTAAGTTAAGTAAGTTATTAAACAATAACTTCACAAGATGTTCAAATCGATTTATCACTGAAAGAAGATCTATGAAAATGTGTTTTGACCAAACTTAGTATTAGGCAGGTACACAGATAAGATTTTCCATTCTTAACATTCTCACTGTAATGCACGACATTTGAAGCACCTGGATGTGCTATCAATCAGGTGGGAAATTTAGCATTATATATTGGAAGCATTGAGAAACATTGGTCTTTCATTTCTATTTTTTTTTCCCCTCCTTTCCTCCTCCTGCCCCACAATATATTATTCATCTGGTTTTAATGCTACATAAATATGCATTGTCTCATGCCTGTTTGTGTTGGATGCCTTGTGCTAAGCTGTAACAAAATGTTGCTTCTTTTGCTGTCTGTATACAGCTGCTTGCTTTAAATTAGTAGATTCTGAAATAGCTTTCCTTGCATGTCTAAAATAAAAGTATTGCATGTA

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