Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SNRNP200P4
Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr17:64750403-64751598  UCSC
Coordinates (T2T) chr17:65620156-65621351  UCSC
Coordinates (hg19) chr17:62746521-62747716  UCSC
Strand +
Parental Sequence NM_014014.5
Parental seq. overlap 1119 bp
Parental seq. overlap (%) 15.5%
Genomic Region Intergenic
Retrocopy Summary SNRNP200P4, located on chr17:64750403-64751598, is a retrocopy of the parental gene SNRNP200. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SNRNP200
Full Name small nuclear ribonucleoprotein U5 subunit 200
Also known as ASCC3L1|BRR2|HELIC2|RP33|U5-200KD
Coordinate chr2:96274338-96305546
Strand -
Gene summary Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SNRNP200P1
Bonobo Pan paniscus SNRNP200P1
Gorilla Gorilla gorilla SNRNP200P1
Orangutan Pongo abelii SNRNP200P1
Gibbon Nomascus leucogenys SNRNP200P1
Green monkey Chlorocebus sabaeus SNRNP200P1
Crab-eating macaque Macaca fascicularis SNRNP200P1
Rhesus Macaca mulatta SNRNP200P1
Baboon Papio anubis SNRNP200P1
Golden snub-nosed monkey Rhinopithecus roxellana SNRNP200P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SNRNP200P4
cAAGGTGCGAGGGCTTATTGAGATCATCTCCAATGCAGCAGGGTACGAGAATATCCCCATCCAGCACCATGAAGAAAACTTCCTGAGGCAGTTGGCTCAGAAGGTCCCTGACAAGCTGAATAACCCTAAGTTCAATGATCCGCACATCAAGACCAACCTGCTCCTGCAGGCTCACCTGTCCCGCATGCAGCTGAGTGCTGAGTTGCAGTCAGATACGGAGGAAATCCTTAGTAAGGCAGTCCGGCTCGTCCAGGCCTGCGTGGATGTCCTCTCCAGCAATGGGTGGCTCAGCTCTGCTCTGGCAGCTATGGAATTGGCCCAGATGGTCACCCAAGCCATGTGGTCCAAGGACTCATACCTGAAGCAGCTGCCACACTTCATCTCTGAGCATATCAAACGTTGCACAGACAAGGGAGTGAAGAGTGTTTTCGACATCATGGAGATGGAGGATGAAGAACGGAACACAATTCTTCAGCTGACTGACAGCCAGATTACAGATGTGGCTCGCTTTTGTAACTGCTACCCTAATATCGAACTATCTTAGGAGGTGGTGGATAAGGACAGCATCCGCAGTGGCGGGCCAGCGGTGGTGCTGGTGCAGCTGGAGCGAGAGGAGGAAGTCACAGGCCCTGTCATTGCGCCTCTCTTCCCGCAGAAACGTGAAGAGGGCTGGTGGGTGGTGATTGGAGACACCAAGTCCAATAGCCTCATCTCCATCAAGAGGCTGATCCTGCAGCAGAAGGCCAAGGTGAAGTTGGACTTTGTGGCTCCAGCCACTGGTGCCCACAACTACACTCTATACTTCATGAGTGATGCTTACATGGGATGTGACCAGGAGTACAAATTCAGCATGGATGTGAAAGAAGCCGAGACGGACAGTGATTCAGATTGAGTCCTGAGGCATTTACTCTTGGGTAAAGGAGAGTTGAGCCTGAATTAGGAATGTGTATATTGTAGGGATCCTGGTGGTTATGGGGACCACGTCTGTGGGCCTGAGGTCTGGCCAGCCAGGGCTGGTGCTGTCCCTGCCCACATCCACTTCCTTTTCCCTTGTTCACACTCTGGATCCAGTGACAGCAGGTGTCACGGGTCAAGCATAAATCATATATAGCATGTTCAGGCATGTTACTGGTAGTTCCTTTTGAGTCTGACATTCTAATAAAATAATTTGTAGAAACCA
>NM_014014.5
AGTGCGTCTTTCCTGCGTCGTTCCGGCGCGGCGGGAGCAGAGATCTGCGGCCGTTTGCAGCTTGCGGTAGGGAGGCGTGGTGGTCTGAAGCCTCCGAGCAGCCGCGGCCATGGCGGATGTAACCGCCCGTAGTCTGCAATACGAGTACAAGGCGAACTCGAATCTTGTGCTCCAAGCTGACCGTTCTCTCATTGACCGGACCCGCCGGGATGAACCCACAGGAGAGGTGCTGTCCCTTGTTGGGAAGCTGGAGGGCACCCGTATGGGAGACAAGGCTCAACGGACCAAACCGCAGATGCAGGAGGAAAGAAGAGCCAAGCGAAGAAAGCGTGATGAGGACCGGCATGACATCAACAAGATGAAGGGTTATACTCTGCTGTCGGAGGGCATTGATGAGATGGTGGGCATCATCTACAAGCCCAAAACTAAAGAGACTCGGGAGACCTATGAGGTGCTACTCAGCTTCATCCAGGCTGCTCTTGGGGACCAGCCACGTGATATCCTTTGTGGGGCAGCTGATGAAGTTCTAGCTGTTCTAAAGAATGAAAAGCTGCGGGACAAGGAAAGGCGAAAGGAGATTGACCTGCTGCTGGGTCAAACAGATGATACCAGATACCATGTGCTAGTGAACCTGGGCAAAAAGATCACAGACTATGGTGGAGATAAGGAAATCCAAAATATGGATGACAACATTGATGAGACATACGGTGTGAATGTGCAGTTTGAGTCTGATGAGGAGGAAGGTGATGAAGACGTATACGGGGAGGTTCGAGAAGAGGCATCTGATGATGACATGGAAGGGGACGAGGCTGTCGTGCGCTGCACCCTCTCGGCTAATCTCGTAGCCTCAGGTGAACTGATGAGTTCCAAGAAGAAGGATTTGCACCCTCGGGATATTGATGCATTTTGGCTGCAGCGGCAGCTCAGTCGTTTCTATGATGATGCCATCGTGTCGCAGAAGAAGGCAGATGAAGTATTGGAGATTTTGAAGACGGCCAGTGATGATCGGGAATGTGAAAATCAGCTGGTTCTGCTGCTTGGTTTCAACACCTTTGATTTCATTAAAGTGTTGCGGCAGCACAGGATGATGATTTTATACTGTACCTTGCTGGCCAGTGCACAAAGTGAAGCTGAAAAGGAAAGGATTATGGGAAAGATGGAAGCTGACCCAGAGCTATCCAAGTTCCTCTACCAGCTTCATGAAACCGAGAAGGAGGATCTGATCCGAGAGGAAAGGTCCCGGAGAGAGCGAGTGCGTCAGTCTCGAATGGACACAGATCTGGAAACCATGGATCTCGACCAGGGTGGAGAGGCACTGGCTCCACGGCAGGTTCTGGACTTGGAGGACCTGGTTTTTACCCAAGGGAGCCACTTTATGGCCAATAAACGCTGTCAGCTTCCTGATGGATCCTTCCGTCGCCAGCGTAAGGGCTATGAAGAGGTGCATGTGCCTGCTCTGAAGCCCAAGCCCTTTGGCTCAGAAGAACAACTGCTTCCAGTGGAAAAGCTGCCAAAGTATGCCCAGGCTGGGTTTGAGGGCTTCAAAACACTGAATCGGATCCAGAGTAAGCTCTACCGTGCTGCCCTTGAGACGGATGAGAATCTGCTGCTGTGTGCTCCTACTGGTGCTGGGAAGACCAACGTGGCCCTGATGTGCATGCTCCGAGAGATTGGGAAACACATAAACATGGACGGCACCATCAATGTGGATGACTTCAAGATTATCTACATTGCCCCCATGCGCTCCTTGGTGCAGGAGATGGTGGGCAGCTTTGGAAAGCGCCTGGCCACTTATGGCATCACTGTTGCTGAACTGACTGGGGACCACCAGCTGTGCAAAGAAGAGATCAGTGCCACTCAGATCATCGTCTGCACCCCCGAGAAGTGGGACATCATCACCCGCAAGGGTGGTGAGCGCACCTACACCCAGCTGGTGCGGCTCATCATTCTGGATGAGATTCATCTTCTCCACGATGACAGAGGTCCTGTCTTAGAAGCTTTAGTGGCCAGGGCCATCCGAAACATTGAGATGACCCAAGAGGATGTCCGACTCATTGGTCTCAGTGCCACCCTACCCAACTATGAAGATGTAGCCACCTTTCTACGTGTTGACCCTGCCAAGGGTCTCTTTTACTTTGACAACAGCTTCCGTCCAGTGCCTCTGGAACAGACATATGTGGGTATCACAGAGAAAAAAGCTATCAAGCGTTTCCAGATCATGAATGAAATCGTCTATGAAAAAATCATGGAACATGCTGGAAAAAATCAGGTGCTGGTGTTTGTCCACTCCCGGAAGGAGACTGGAAAGACAGCCAGGGCCATCCGGGACATGTGCCTAGAAAAGGACACTCTGGGTCTGTTTCTGAGGGAGGGCTCAGCCTCCACAGAAGTCCTGCGAACAGAAGCTGAGCAGTGCAAGAACCTAGAGCTGAAGGATCTTCTGCCTTATGGCTTTGCTATTCATCACGCAGGCATGACCAGGGTTGACCGAACACTCGTGGAGGATCTTTTTGCTGATAAACATATTCAGGTTTTAGTTTCCACAGCAACTCTAGCTTGGGGTGTGAATCTCCCTGCACATACAGTCATCATCAAAGGCACCCAGGTGTACAGTCCAGAGAAGGGGCGTTGGACAGAACTGGGAGCACTGGACATTCTGCAGATGCTGGGACGTGCCGGAAGACCCCAGTATGACACCAAGGGTGAAGGCATACTCATCACATCTCATGGGGAGCTACAGTACTACCTGTCCCTCCTCAATCAACAACTTCCTATTGAAAGCCAGATGGTTTCAAAGCTTCCTGACATGCTCAATGCAGAAATCGTGCTAGGAAATGTCCAGAATGCCAAGGATGCGGTGAACTGGCTGGGCTATGCCTACCTCTATATCCGAATGCTGCGATCCCCAACCCTCTATGGCATCTCTCATGATGACCTCAAGGGAGATCCCCTGCTGGACCAGCGCCGACTAGATCTGGTTCATACAGCTGCCCTGATGCTGGACAAGAACAATCTGGTCAAGTACGACAAGAAGACGGGCAACTTCCAGGTGACAGAACTGGGCCGTATAGCCAGCCACTACTACATCACCAATGATACAGTGCAGACTTACAACCAGCTGCTGAAGCCCACCCTGAGTGAGATTGAGCTTTTCAGGGTCTTCTCATTGTCCTCTGAGTTCAAGAACATCACAGTGAGAGAGGAGGAGAAGCTGGAGCTGCAGAAGTTGCTGGAGAGGGTGCCTATCCCTGTAAAGGAGAGCATTGAGGAACCCAGTGCTAAGATCAACGTTCTTCTGCAAGCCTTCATCTCACAGCTGAAATTGGAGGGCTTTGCACTGATGGCTGACATGGTGTATGTCACACAGTCGGCTGGCCGGTTGATGCGAGCGATATTTGAAATTGTCCTGAACCGAGGTTGGGCACAGCTTACAGACAAGACCCTGAACCTCTGCAAGATGATCGACAAACGCATGTGGCAGTCCATGTGTCCTCTGCGCCAGTTCCGGAAACTCCCTGAGGAAGTAGTGAAGAAGATTGAGAAGAAGAATTTCCCCTTTGAGCGTCTGTACGACCTGAATCATAATGAGATTGGGGAGCTTATCCGCATGCCAAAGATGGGGAAGACCATCCACAAATATGTCCATCTGTTTCCCAAGTTGGAGTTGTCAGTGCACCTGCAGCCTATCACACGCTCCACCCTGAAGGTGGAGCTGACCATCACGCCAGACTTCCAGTGGGATGAAAAGGTGCATGGTTCATCCGAGGCTTTTTGGATTCTGGTGGAGGATGTGGACAGCGAGGTGATTCTGCACCATGAGTATTTTCTCCTCAAGGCCAAGTACGCCCAGGACGAGCACCTCATTACATTCTTCGTGCCTGTCTTTGAACCGCTGCCCCCTCAGTACTTCATCCGAGTGGTGTCTGACCGCTGGCTCTCTTGTGAGACCCAGCTGCCTGTCTCCTTCCGGCACCTGATCTTGCCGGAGAAGTACCCCCCTCCAACCGAACTTTTGGACCTGCAGCCCTTGCCCGTGTCTGCTCTGAGAAACAGTGCCTTTGAGAGTCTTTACCAAGATAAATTTCCTTTCTTCAATCCCATCCAGACCCAGGTGTTTAACACTGTATACAACAGTGACGACAACGTGTTTGTGGGGGCCCCCACGGGCAGCGGGAAGACTATTTGTGCAGAGTTTGCCATCCTGCGAATGCTGCTGCAGAGCTCGGAGGGGCGCTGTGTGTACATCACCCCCATGGAGGCCCTGGCAGAGCAGGTATACATGGACTGGTACGAGAAGTTCCAGGACAGGCTCAACAAGAAGGTGGTACTCCTGACAGGCGAGACCAGCACAGACCTGAAGCTGCTGGGCAAAGGGAACATTATCATCAGCACCCCTGAGAAGTGGGACATACTTTCCCGGCGATGGAAGCAGCGCAAGAACGTGCAGAACATCAACCTCTTCGTGGTGGATGAGGTCCACCTTATCGGGGGCGAGAATGGGCCTGTCTTAGAAGTGATCTGCTCCCGAATGCGCTACATCTCCTCCCAGATTGAGCGGCCCATTCGCATTGTGGCACTCAGCTCTTCGCTCTCCAATGCCAAGGATGTGGCCCACTGGCTGGGCTGCAGTGCCACCTCCACCTTCAACTTCCATCCCAATGTGCGTCCCGTCCCCTTGGAGCTGCACATCCAGGGCTTCAACATCAGCCATACACAAACCCGCCTGCTCTCCATGGCCAAGCCTGTGTACCATGCTATCACCAAGCACTCGCCCAAGAAGCCTGTCATTGTCTTTGTGCCGTCTCGCAAGCAGACCCGCCTCACTGCCATTGACATCCTCACCACCTGTGCAGCAGACATCCAACGGCAGAGGTTCTTGCACTGCACCGAGAAGGATCTGATTCCGTACCTGGAGAAGCTAAGTGACAGCACGCTCAAGGAAACGCTGCTAAATGGGGTGGGCTACCTGCATGAGGGGCTCAGCCCCATGGAGCGACGCCTGGTGGAGCAGCTCTTCAGCTCAGGGGCTATCCAGGTGGTGGTGGCTTCTCGGAGTCTCTGCTGGGGCATGAACGTGGCTGCCCACCTGGTAATCATCATGGATACCCAGTACTACAATGGCAAGATCCACGCCTATGTGGATTACCCCATCTATGACGTGCTTCAGATGGTGGGCCACGCCAACCGCCCTTTGCAGGACGATGAGGGGCGCTGTGTCATCATGTGTCAGGGCTCCAAGAAGGATTTCTTCAAGAAGTTCTTATATGAGCCATTGCCAGTAGAATCTCACCTGGACCACTGTATGCATGACCACTTCAATGCTGAGATCGTCACCAAGACCATTGAGAACAAGCAGGATGCTGTGGACTACCTCACCTGGACCTTTCTGTACCGCCGCATGACACAGAACCCCAATTACTACAACCTGCAGGGCATCTCCCATCGTCACTTGTCGGACCACTTGTCAGAGCTGGTGGAGCAGACCCTGAGTGACCTGGAGCAGTCCAAGTGCATCAGCATCGAGGACGAGATGGACGTGGCGCCTCTGAACCTAGGCATGATCGCCGCCTACTATTACATCAACTACACCACCATTGAGCTCTTCAGCATGTCCCTCAATGCCAAGACCAAGGTGCGAGGGCTTATCGAGATCATCTCCAATGCAGCAGAGTATGAGAACATTCCCATCCGGCACCATGAAGACAATCTCCTGAGGCAGTTGGCTCAGAAGGTCCCCCACAAGCTGAATAACCCTAAGTTCAATGATCCGCACGTCAAGACCAACCTGCTCCTGCAGGCTCACTTGTCTCGCATGCAGCTGAGTGCTGAGTTGCAGTCAGATACGGAGGAAATCCTTAGTAAGGCAATCCGGCTCATCCAGGCCTGCGTGGATGTCCTTTCCAGCAATGGGTGGCTCAGCCCTGCTCTGGCAGCTATGGAACTGGCCCAGATGGTCACCCAAGCCATGTGGTCCAAGGACTCATACCTGAAGCAGCTGCCACACTTCACCTCTGAGCATATCAAACGTTGCACAGACAAGGGAGTGGAGAGTGTTTTCGACATCATGGAGATGGAGGATGAAGAACGGAACGCGTTGCTTCAGCTGACTGACAGCCAGATTGCAGATGTGGCTCGCTTTTGTAACCGCTACCCTAATATCGAACTATCTTATGAGGTGGTAGATAAGGACAGCATCCGCAGTGGCGGGCCAGTTGTGGTGCTGGTGCAGCTGGAGCGAGAGGAGGAAGTCACAGGCCCTGTCATTGCGCCTCTCTTCCCGCAGAAACGTGAAGAGGGCTGGTGGGTGGTGATTGGAGATGCCAAGTCCAATAGCCTCATCTCCATCAAGAGGCTGACCTTGCAGCAGAAGGCCAAGGTGAAGTTGGACTTTGTGGCCCCAGCCACTGGTGCCCACAACTACACTCTGTACTTCATGAGTGACGCTTACATGGGATGTGACCAGGAGTACAAATTCAGCGTGGATGTGAAAGAAGCTGAGACAGACAGTGATTCAGATTGAGTCCTGAGGCATTTACTTTTGGGTAAAGGAGAGTTGAGCCTGAATTAGGAATGTGTACATTGTAGGAATCCTGGTTGTGGGGACCAGGTCTGTGGGCCTCAGGTCTGGCCAGCCAGGGCTGGTGCTGTCCCCGCCTACCTCCACTTCCTTTCCCTTGCTCACTCTGGATCCAGTGACAGCAGGTGTCATGGGTCAAGCATAAATCATATATAGCATTTTCAGGCATGTTCCTGGTAGTTCTTTTGAGTCTGACATTCTAATAAAATAATTTGTAGAAACCATTTGTCTTTGTAGTGATTCCAAATTAAAAGTTTTCTTTCTCCAACCTGAGGGCACGGCCAAAAAGATCTGGTTATTTTTTAGCCAGGAACGTGCTTGTTAATGAGTATGTCTGGAGGACAGACCTGCTCATTAGGTGTGCTGTCCCCTGTAGCCTCGTGAGTCAGCCCAGAGGAGGGTACATGCGACTGTGGCCTGGCCTCAGTGGTACCCACACATCAGCACTACCACAAGAACCAACACTGAGCCTCGGAAGCTAGATCACAGGTTAGGGGTTTCTCTAGATGGGGGTTCTGAAATTTGCAGTGTCTGCTCCTGGGAGGCAGCACCAGAAAGGGCACTGAAATGTACTAGCTGGATGTGACCCAGTCTTAATAAACAGGTTTTCTAATCCA

Publications

PMID - Link Title