Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PTGES3L-AARSD1P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:77194817-77195469  UCSC
Coordinates (T2T) chr1:77032981-77033633  UCSC
Coordinates (hg19) chr1:77660502-77661154  UCSC
Strand +
Parental Sequence NM_025267.4
Parental seq. overlap 612 bp
Parental seq. overlap (%) 34%
Genomic Region Intragenic (PIGK)
Retrocopy Summary PTGES3L-AARSD1P1, located on chr1:77194817-77195469, is a retrocopy of the parental gene PTGES3L-AARSD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PTGES3L-AARSD1
Full Name PTGES3L-AARSD1 readthrough
Also known as -
Coordinate chr17:42950526-42980528
Strand -
Gene summary This locus represents naturally occurring readthrough transcription between the neighboring PTGES3L (prostaglandin E synthase 3 (cytosolic)-like) and AARSD1(alanyl-tRNA synthetase domain containing 1) genes on chromosome 17. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, May 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AARSD1P1
Bonobo Pan paniscus AARSD1P1
Gorilla Gorilla gorilla AARSD1P1
Orangutan Pongo abelii AARSD1P1
Gibbon Nomascus leucogenys AARSD1P1
Green monkey Chlorocebus sabaeus LOC103243378P1
Crab-eating macaque Macaca fascicularis AARSD1P1
Rhesus Macaca mulatta LOC712203P1
Baboon Papio anubis LOC101016032P1
Golden snub-nosed monkey Rhinopithecus roxellana LOC104679976P2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PTGES3L-AARSD1P1
ACTCAGTGACCAGGTCATCAAGATTCTGGGCACTGAGAAACGGAAAAAGAACAAAACCAACCTGATATTTCGGACAGGGAACCAGGTGGTCAAATGGATGGACAGAAGTCATGGAACTGAAAAAGCACTGACTACTCCTGCTTAAGTGTGGAGCAGAGGATCACGTGGAAGCAGTGAAAAAGCTCCAAACTCCACCAAGCTCCTGCAGAAGAATAACCTGAATCTGCTCAGAGACCTGGCTGTGCACACTGCCCATAGCAGGAACAACCCAGACTGGTGAGGTGTGGTCATATTACACAGGAAGGAGGGTGATTCAGAGTTCATGAATATCATTGCCAATGAGATTGGGTCAGAGGAGACCCTCCTGTTCTTAACCGTGGGCGATGAGAAAGGTGCTGGACTTTTCTTACTGGCAGGGCGACCTGCAGCTGTGGAGACCTTGGGGCCCAGGGTGGCTGAGGTCCTGGAAGGCAAAGGAGCAGGGAAGAAAGGCTGTTTTCAGGGCAAGACCACCAAGTTGAGCCAGCGGGCGGAGGCACAGGCACTTCTCCAGGACTACATCAGCACGCAGAGTGCTAAGGAGTGAGAGCTTAGGGTGCTCACTTCCTGTTTCCACAGGAATCTTTTGGTCAATAAAATAGTTTGACTCAGAA
>NM_025267.4
CCTTTTCCCTGGAGATTCCCTGCTCCAAGTCTTCTGGGCGCTCCAGGTTCTGTGAGGCCCCACGGGAGCCCCGGACCCCTGGTCTCTGTAACTGTGGGGTGAGGGAAGGCAGCACGCCCGGACCTTGTGGTACGACAGGCCCAGGTATGTGTTCATGGAGTTTTGTGTTGAGGACAGCACCGATGTCCACGTGCTTATTGAGGATCACCGCATTGTGTTCAGCTGCAAGAATGCCGATGGAGTGGAGTTGTACAATGAGATTGAGTTCTATGCCAAAGTGAACTCCAAGGACTCCCAGGATAAGCGCTCTTCCCGCTCTATTACTTGTTTTGTGAGAAAATGGAAGGAAAAGGTGGCCTGGCCGCGGCTTACCAAGGAGGATATCAAGCCAGTGTGGCTGTCTGTGGACTTTGATAACTGGAGAGACTGGGAAGGGGATGAAGAGATGGAGCTGGCTCATGTGGAACATTATGCAGAGCTTTTGAAGAAGGTCAGCACCAAGAGACCTCCACCTGCCATGGATGATTTGGATTTCACCACCACCGTGGTCTCCTGCTGTCCCGCGGAGCTGCAGACTGAAGGGAGCAACGGCAAGAAAGAAGTGCTGAGCGGTTTCCAAGTGGTGCTGGAAGACACAGTGCTTTTCCCTGAGGGCGGGGGACAGCCTGATGACCGTGGTACAATCAATGACATCTCTGTGCTGAGAGTGACTCGCCGTGGGGAACAGGCTGATCATTTCACCCAGACACCCCTGGATCCAGGAAGCCAGGTTCTGGTCCGGGTAGATTGGGAGCGGAGGTTTGACCACATGCAGCAGCATTCAGGGCAGCATCTCATCACGGCAGTTGCTGACCATCTATTTAAGCTGAAGACAACATCATGGGAGTTAGGGAGATTTCGGAGTGCGATTGAGCTGGACACCCCCTCTATGACTGCAGAGCAAGTAGCTGCCATTGAGCAGAGCGTCAATGAAAAAATCAGAGATCGGCTGCCTGTGAATGTCCGAGAACTGAGCCTGGATGATCCTGAGGTGGAGCAGGTGAGTGGCCGGGGTTTGCCTGATGATCATGCTGGGCCCATTCGGGTTGTTAACATCGAGGGCGTTGATTCCAACATGTGCTGTGGGACCCATGTGAGCAATCTCAGTGACCTTCAGGTCATTAAGATTCTGGGCACTGAGAAGGGGAAAAAGAACAGAACCAACCTGATATTTCTGTCTGGGAACCGGGTGCTGAAGTGGATGGAGAGAAGTCATGGAACTGAAAAAGCACTGACTGCTCTGCTTAAGTGTGGAGCAGAGGATCATGTGGAAGCAGTGAAAAAGCTCCAGAACTCCACCAAGATCCTGCAGAAGAATAACCTGAATCTGCTCAGAGACCTGGCTGTGCACATTGCCCATAGCCTCAGGAACAGTCCAGACTGGGGAGGTGTGGTCATATTACACAGGAAGGAGGGTGATTCAGAGTTCATGAATATCATTGCCAATGAGATTGGGTCAGAGGAGACCCTCCTGTTCTTAACTGTGGGCGATGAGAAAGGTGGTGGACTCTTCTTACTGGCAGGGCCACCTGCGTCTGTGGAGACCCTGGGGCCCAGGGTGGCTGAGGTCCTGGAAGGCAAAGGAGCAGGGAAGAAAGGCCGTTTTCAGGGCAAGGCCACCAAGATGAGCCGGCGGATGGAGGCGCAGGCGCTTCTCCAGGACTACATCAGCACGCAGAGTGCTAAGGAGTGAGGGCTTAGGGCACTCACCTCCTGTTTCCACAGGAATCTTTTGGTCAATAAAATAGATTGACTCAGAA

Publications

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