Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PSAT1P3
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:79053926-79056122  UCSC
Coordinates (T2T) chr1:78892420-78894618  UCSC
Coordinates (hg19) chr1:79519611-79521807  UCSC
Strand -
Parental Sequence NM_021154.5
Parental seq. overlap 1950 bp
Parental seq. overlap (%) 87.9%
Genomic Region Intergenic
Retrocopy Summary PSAT1P3, located on chr1:79053926-79056122, is a retrocopy of the parental gene PSAT1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PSAT1
Full Name phosphoserine aminotransferase 1
Also known as EPIP|NLS2|PSA|PSAT|PSATD
Coordinate chr9:78297125-78330093
Strand +
Gene summary This gene encodes a member of the class-V pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is a phosphoserine aminotransferase and decreased expression may be associated with schizophrenia. Mutations in this gene are also associated with phosphoserine aminotransferase deficiency. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, and 8. [provided by RefSeq, Jul 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PSAT1P1
Bonobo Pan paniscus PSAT1P1
Gorilla Gorilla gorilla PSAT1P1
Orangutan Pongo abelii PSAT1P1
Gibbon Nomascus leucogenys PSAT1P2
Green monkey Chlorocebus sabaeus PSAT1P5
Rhesus Macaca mulatta PSAT1P1
Baboon Papio anubis PSAT1P1
Golden snub-nosed monkey Rhinopithecus roxellana PSAT1P3
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PSAT1P3
GCCAGGAACACTAGCCGTTCACGTGTTCGGTCCTCCTTAGCTGACTCGCCGCCCTCGCTGCCGCACCATGGACGCCCCGAGGCACGTGGTCAACTTCGGGCCTGGTCCCGCCAAGCTGCCTCACTCAGTGTTGTTAGAGATAAAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTAGTGTTCTTGAAATGAGTCACAGGCCATCAGATTTTGCCAAGATTATTAACGATACAGAGAATCTTGTGCGGGAATTGCTAGCCGTTCCAGACAGCTGTAAGGTGATTTTTGTGCAAGGAAGTGGGTCTGGCCAGTTCGGTGCTGTCCCCTTAAACCTGATTGGCTTGAAAGCAGGAAGATGTGCGGACTATGTGGTGACAGGGACTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCATTCACCCTAAACTTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCGGATGCCTCCTATGTGTATTATTGCGCAAATGAGGTGGTGCATGGTGTGGAGTTTGACTTTATACCCTATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATGTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGACGAATGTTGGCTTTGCTGGGGTCACTGTGGTGATTGTCTGTGATGACCTGCTGGGGTTTGCCCTCTGAGAGTGCCCCTTGGTCCTAGAATACGAGGTACAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGCATCTATGTCATGGGCTTGGTCCTGGAGTGGATTAAAAACAATGGAGGTGCCGCGGCCATGGAGAAGCTTAGCTCCATCAAATCTCAAATGATTTATGAGATTATTGATAATTCTCAAGGATTCTACGTATGTCCGGTGGAGCCCCAAAATAGAAGCAAGATGAATATTCCATTCTGCATTTGCAATGCCAAAGGAGATGATGCTTTAGAAAAAAGACTTTTTGATAAAGCTCTTGAACTTAATATGTTGCCCTTGAAAGGGTATAGGTCTGTGGGAGGCATCCGGGCCTCTCTGTATAATGCTGTCACTATTGAAGATGTTCAGAAGCTGGCCGCCTTCATGAAAAATTTTTTGGAGATGCATCAGCTATGAACACATCCTAACCAGGATATACTCTGTTCTTGAACAACATACAAAGTTTAAAGTAACTTGGGTATGGCTACAAAAGGTTAACAAACACAGTATTTTCCTCAAATGAACATGTTTATTGTAGATTCTTCTTTTTTGAAAGAACAACAGCAAAACATCTACAGCTCTGTAAAGCTGGTGGGAACTAATGTTCACCTTAATTCTGACTTGAACTGGAAGCATTTTAAGAAATCTTCTCATTGCTTTTCTAACAAATTCCCGCTTGTTTAGCCTTTGCTGCTACTTTTTCTAGTTAGATTTCCAACTTGCCTGTGGACTTCATACTGCAAGTTGCAATTAATTATTTCTAGAGTCATGGGAACACACAGCATAGAGGGTAGGTGGGGCCCTCTAGGTGCTGAATCTAAACATCTGTGGGGTCTCCTGTGTTCAGAGGCTGTTGATTCAAGGTCAACATTGACCACTGGAGGAGTGGTTTAAGAGTACCAGGCAAAGGGCAAACTGAAGATTGATCATTATACTGTTATTACAAGAGAAGTGTCATACTTTATATATGTTTATATTAGCAAGGTCTGTTTTTAATACCATATACTTTATATTTCTATACTTTTATATTTCTAATAATACGGTTATCATTGATACATGTAGACACTTTTAGAATTTATTAAATCCTTGACCTTGTGCATTATAGCATTCCATTAGCAACAGTTGCACCCCCTCCCCAGTCTTCCTCTTCCTCTTTTTAAGCTGTTTTATGAAAAACATCTCGAAGTTCTTGATTCATTTTTACCGTTCTTTCCATAGGTAGAAGAGAAAGTTGATTGGTTGGTTGTTTTTCAATTATGCCATTAAACTAAACATTTCTGTTAAATTACCTTATCCTTTGTTCTCCTGACTGTTTTCTTTGTAATGTTTGACGATGAGAGTGATACTTTGCTCAAAAGTCTTTCCCCTATTGTTTATCTATTGTCAGTATTTTATGTTGAATATGTGAAGAACATTAAAGTCCTAAAACATCTAAA
>NM_021154.5
GCAGACTCTCACCGCAGCGGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGGTCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTAGTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAGACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGTGTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAACTTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGCATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATGTTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGGGGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGCATCTACGTCATGGGCTTGGTTCTGGAGTGGATTAAAAACAATGGAGGTGCCGCGGCCATGGAGAAGCTTAGCTCCATCAAATCTCAAACAATTTATGAGATTATTGATAATTCTCAAGGATTCTACGTGTCTGTGGGAGGCATCCGGGCCTCTCTGTATAATGCTGTCACAATTGAAGACGTTCAGAAGCTGGCCGCCTTCATGAAAAAATTTTTGGAGATGCATCAGCTATGAACACATCCTAACCAGGATATACTCTGTTCTTGAACAACATACAAAGTTTAAAGTAACTTGGGGATGGCTACAAAAAGTTAACACAGTATTTTTCTCAAATGAACATGTTTATTGCAGATTCTTCTTTTTTGAAAGAACAACAGCAAAACATCCACAACTCTGTAAAGCTGGTGGGACCTAATGTCACCTTAATTCTGACTTGAACTGGAAGCATTTTAAGAAATCTTGTTGCTTTTCTAACAAATTCCCGCGTATTTTGCCTTTGCTGCTACTTTTTCTAGTTAGATTTCAAACTTGCCTGTGGACTTAATAATGCAAGTTGCGATTAATTATTTCTGGAGTCATGGGAACACACAGCACAGAGGGTAGGGGGGCCCTCTAGGTGCTGAATCTACACATCTGTGGGGTCTCCTGGGTTCAGCGGCTGTTGATTCAAGGTCAACATTGACCATTGGAGGAGTGGTTTAAGAGTGCCAGGCGAAGGGCAAACTGTAGATCGATCTTTATGCTGTTATTACAGGAGAAGTGACATACTTTATATATGTTTATATTAGCAAGGTCTGTTTTTAATACCAtatactttatatttctatacatttatatttctaataataCAGTTATCACTGATATATGTAGACACTTTTAGAATTTATTAAATCCTTGACCTTGTGCATTATAGCATTCCATTAGCAAGAGTTGTACCCCCTCCCCAGTCTTCGCCTTCCTCTTTTTAAGCTGTTTTATGAAAAAGACCTAGAAGTTCTTGATTCATTTTTACCATTCTTTCCATAGGTAGAAGAGAAAGTTGATTGGTTGGTTGTTTTTCAATTATGCCATTAAACTAAACATTTCTGTTAAATTACCCTATCCTTTGTTCTCTACTGTTTTCTTTGTAATGTATGACTACGAGAGTGATACTTTGCTGAAAAGTCTTTCCCCTATTGTTTATCTATTGTCAGTATTTTATGTTGAATATGTAAAGAACATTAAAGTCCTAAAACATCTAA

Publications

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