Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MRTO4P2
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:13139631-13140516  UCSC
Coordinates (T2T) chr18:13302367-13303252  UCSC
Coordinates (hg19) chr18:13139630-13140515  UCSC
Strand -
Parental Sequence NM_016183.4
Parental seq. overlap 791 bp
Parental seq. overlap (%) 38.5%
Genomic Region Intergenic
Retrocopy Summary MRTO4P2, located on chr18:13139631-13140516, is a retrocopy of the parental gene MRTO4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MRTO4
Full Name MRT4 homolog, ribosome maturation factor
Also known as C1orf33|MRT4|dJ657E11.4
Coordinate chr1:19251799-19260128
Strand +
Gene summary This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MRTO4P2
Bonobo Pan paniscus MRTO4P2
Orangutan Pongo abelii MRTO4P2
Gibbon Nomascus leucogenys MRTO4P1
Marmoset Callithrix jacchus MRTO4P3
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MRTO4P2
TCTTCCACCACACGTGGCTTCAGAACAATGCCCAAATCCAAGCATGACAAGGAAGTCCCTAACCAAAACTGCCAAGAAAGGCCTGGAATTGAAACAACACCTGATAGAAGAGCTTCGGAAACGTGTGGACACTGATAAGTACCTTTCCATCTCTCTGTGGCCAACACGTGGAACAGCAAGCTGAAGGACATCCGGAATGCCTGGAAGCACAGCCGGATGTTCTTTGGCAAAAACAAGGTGATGATGGTGGCCTTGGGTCGGAGCCCATTGGGTGAGTGCAAAGACAACCTGCACCAGGTCAGCAAAAGGTTGAGGGGTGAAGCGGATCTCCTGTTCACCAACCACTGGAAGGAGGAGGTGAATGAGTGGTTCACAGAATACACGGAAATGGACTTCAGCTGAGCTGTAACAAAGCAGCTTTCACCGTGAGCCTGGACCCAGGGCCCCTGGAGCAGTTCCCCACCCCATGAAGCCACAGCTGAGGCAGCCGGGCCTGCCCACCACCTTTGAGAGAGGTGTGGTGACCCTGCTGTCCGACAATGAGGTGTGCAAGGAGGGCCACCTGCTGGCCCCGGAGCAGGCTGGTGTTCTGATGCTTTCTGGGTATGAGATGGCTGAATTTAAGGTGACCATCAAATACATGTGGGATGTACAGTCAGGAAGGGTCCAGCAGATGGGAGACGACCTGCCAGAGAGCTCATCCAACTCAGCAGAAGAATCAAGACTCAGACGATGATGACTGAAAGGGACTCAGGACTGAAGGTCTCCTGGAACCTTCTGGATCTCACTGGACCACACAGGACTACTGCCACTCCTCTAGAGAGAGCAGCTTATTTGGCTTTTGACAGGGAGTGATGGGCACTGACTGTTCCTGTAAAGAATAAAG
>NM_016183.4
ACCGTCTTCCGCCGCACGTGGATTCAGCGCGATGCCCAAATCCAAGCGCGACAAGAAAGTCTCCTTAACCAAAACTGCCAAGAAAGGCTTGGAATTGAAACAAAACCTGATAGAAGAGCTTCGGAAATGTGTGGACACCTACAAGTACCTTTTCATCTTCTCTGTGGCCAACATGAGGAACAGCAAGCTGAAGGACATCCGGAACGCCTGGAAGCACAGCCGGATGTTCTTTGGCAAAAACAAGGTGATGATGGTGGCCTTGGGTCGGAGCCCATCTGATGAATACAAAGACAACCTGCACCAGGTCAGCAAAAGGTTGAGGGGTGAGGTGGGTCTCCTGTTCACCAACCGCACAAAGGAGGAGGTGAATGAGTGGTTCACGAAATACACAGAAATGGACTACGCCCGAGCTGGTAACAAAGCAGCTTTCACTGTGAGCCTGGATCCAGGGCCCCTGGAGCAGTTCCCCCACTCCATGGAGCCACAGCTCAGGCAGCTGGGCCTGCCCACCGCCCTCAAGAGAGGTGTGGTGACTCTGCTGTCTGACTACGAGGTGTGCAAGGAGGGCGATGTGCTGACCCCAGAGCAGGCTCGCGTCCTGAAGCTTTTTGGGTATGAGATGGCTGAATTCAAGGTGACCATCAAATACATGTGGGATTCACAGTCGGGAAGGTTCCAGCAGATGGGAGACGACTTGCCAGAGAGCGCATCTGAGTCCACAGAAGAGTCAGACTCAGAAGATGATGACTGAAAGGGACTCGGGACTGAAGGTCTCCTGGAAGCTTCTGGGTCTCACTGGACCATCAGGACTGCTGCCGCCCCTCTGGAGAGAGCAGCTTTTTATTTGTCTGTAGACAGGGAACATGATGGGCACTGACCTCCTGTAAAGAATAAAACTGTGggccgggcgcggtggctcacgcctggaatcccagcactttgggaagccgaggtgggcagatcataaggtcgggagattaagaccatcctggctaacacggtgaaaccccgtctctactaaaaatagaaaaaaaaactagttgggcatagtggcatgtgcctgtagtcccagctactcaggaggctgaggcaggagaatcacttgaacccgggaggtggaggttgccgtgagttgagattggaccactgctctccagcctgggcaacagagtaaaactctgtcccaaaaaaaaaaaaagaaTACAACCTTGCAGGATGTCTCTCCTGGAGACAGCAAGAGGGAGAGGAGGGAGAGGGCTCTTTCTTAGAAAAGAGGCCTTTGGtgagcccagaagtttgaaaccagcctgggcaattcagcaagatcccgtctctacaaaaaataaaaaaaaattagtcgtggtgccacttgcctgtggtccccactgcttgggaggctgaggtgggagaattgcttaagcctgagagttggaggctcagtgagccatgatcatgccactgcactccagcctgggtgGCCATTGAATTCTGCGTGGATTGCCTCAGTTTGCCTTGTCAGCCAACTTCCACTGGCTGCCTTGGCACTGCCATGACAGCACAGCTCCACACCAGAGCTGGGGTTTCTCTTCAGTCCTGGGTACCCCTTGGCAGAGGGATTTGCTGAGGAAAATTAGGTATCCTTCCTAGCCCTCCACACACTTCCAAACCAGGGCTGCGGATCTGATGGATGCCAGGAAGACAGCCTTGGGCTGAGAGTGACATCACTGCAAGAGTTGAGAGCCAGCGTCTAAAGTGTCCACGGCATCCTGGGAGGTTTTATCCTTGGTGACTCTAATGGTAGATTTTTGTCCACCttgttctatttgcttttgtttgtttttgatttttctgtttTAAAattttaaggagagatggggtttcaccatgttgcccaggctggtctcaaactcctgagctcaagcgatctacccaccttggcctcccaaagtgctgggattataggtgtgagccaccgcatccagccCACATTGTTCTATTTGTATTTCATGAAAGCAGTTCTGAATGAGAGTAAATCAGCTTCAGGGTGTA

Publications

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