Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KATNBL1P3
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:2594431-2594923  UCSC
Coordinates (T2T) chr18:2750191-2750683  UCSC
Coordinates (hg19) chr18:2594430-2594922  UCSC
Strand -
Parental Sequence XM_017022575.2
Parental seq. overlap 427 bp
Parental seq. overlap (%) 17.2%
Genomic Region Intragenic (NDC80)
Retrocopy Summary KATNBL1P3, located on chr18:2594431-2594923, is a retrocopy of the parental gene KATNBL1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KATNBL1
Full Name katanin regulatory subunit B1 like 1
Also known as C15orf29
Coordinate chr15:34140674-34210096
Strand -
Gene summary Predicted to enable microtubule binding activity. Involved in positive regulation of cytoskeleton organization. Located in several cellular components, including cleavage furrow; mitotic spindle pole; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Green monkey Chlorocebus sabaeus KATNBL1P2
Crab-eating macaque Macaca fascicularis KATNBL1P3
Rhesus Macaca mulatta KATNBL1P3
Golden snub-nosed monkey Rhinopithecus roxellana KATNBL1P3
Marmoset Callithrix jacchus KATNBL1P2
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KATNBL1P3
TTAAGAGAATATGACATTTGAAACTCACAATGTGAAAAAAATGGAACTTTTGTAATATCGAGGATCCCTCCATTGACCTTCCTAGAAAAAGGATCTCTAATTTCACTAATACAACATGAAGAAGGTTAAGAAGTCTCCAAGACAGGTGGCTGCTTACATAAACAGAACAGTTGGACAAGGTGTGAAAAGCCCAGATTAAAGCACATAAGGCAGTCTATTTCAGAAAGTTAATCATCCCTTTCTAAATTCTTGTTACAGAAAAAACAGTTGCCTAGAAGTGGGGATTGTGCCACGGCAAATGAGAAAATGAACTGACTTGTGCAGGCTACCTGCCTGAAAAATTAAGCCATGACAGTTGAGTCACACATATTTGATTAATTCCAGTGATTCTGGTTCTTCCCAAACAGAAAACCCATCATCACAGTATAGTGGGTTTTTTTCTAAGGTTTCTCAGGACCATGAAACAATGGCCAAAATTTTGTTCAGCAGGAAA
>XM_017022575.2
CGCGTTTGAATGGCCCTGAGTGGGACTCGGCCCAGAAGCCGAGGGACTCTCTAGGCTGCCGGGCGCTGGTCGTCAGCGCCGAGGCTGGGCTGAGGCGCCGCGGTACCATGAGGCGCCGGTACTTAAGAGATTATGGCATCAGAAACCCACAATGTTAAAAAACGGAACTTTTGTAATAAGATTGAGGATCATTTCATTGATCTTCCTAGAAAAAAGATCTCTAATTTCACTAATAAGAACATGAAGGAGGTTAAGAAATCTCCAAAACAGTTGGCTGCTTACATAAATAGAACAGTTGGACAAACTGTGAAAAGCCCAGATAAACTTCGTAAAGTGATCTATCGCAGAAAGAAAGTTCATCATCCCTTTCCAAATCCTTGTTACAGAAAAAAACAGTCCCCTGGAAGTGGGGGCTGTGACATGGCAAATAAAGAAAATGAACTGGCTTGTGCAGGCCACCTGCCTGAAAAATTACACCATGATAGTCGAACATATTTGGTTAACTCCAGTGATTCTGGTTCTTCACAGACAGAAAGCCCATCATCAAAATATAGTGGGTTTTTTTCTGAGGTTTCTCAGGACCATGAAACAATGGCCCAAGTTTTGTTCAGCAGGAATATGAGATTGAATGTAGCTTTAACTTTCTGGAGAAAGAGAAGTATAAGTGAACTTGTAGCTTATTTGTTGAGAAATATTCAAATTTTAAAACAACAATTAAGTGGATTATGGGAACAGGAAAACCATCTTACTTTGGTTCCAGGATATACTGGTAATATAGCTAAGGATGTAGATGCTTATTTATTACAGTTACATTGAGAGATTTCATCTACTAAAGAGCATTTGGTTTTTCAAAACATCCCTGAACTGTATAATTTACAAAAAAAAAAAGTCTCGTCTGAGAACTGTGAACTGTGGAAGAAATCAAAACTATTTTTTCTTTTAAAAAGCCACGTAATGAAACCACTAATGAAATCCCAGCAATCTGCTTCACATTGAAGTGGAAAAATATCCAAAAGGAGCAGCTTCAATTTCATTGAGGTGAAAGTGCACTATGAAGATTGTTCACCTTTGCTGCATTTGGGAGTTATATGGTTATTTGGTAACATTAAGAACTACTGGATTTTAATGCAATCCTGCATAAAAATATAATTTATACTATGTGAAAAAATAAGACAGGACTTACCACTAGGAACCACCAAGACCAATCATCATTAACTTTTTTAAGATTGTGTTTTATTAAAAAAAAAAAACACTTAAATGTGTGCAGCTATTTTCTTATGTTGAAAAGACTGAAAGTTTAAAACATGAAAAAAATCAATATTAAACATTTTTTGTTCACACTGAGATACTGTGTATGTAAAATGCCTTAATTATTAATAAGCCAATGTGTTATGATACCAATATCTGTTTTAAAAAACTAAAACCAACCATGCTTCTGGCATGATAAAATCATGGAATTAAATCAGGGGTTTACATTCTTGTAGAGTGTTCTTGAAACACTCTCTGCACCATTTTTAAAACTTGAGAATAGTTTTAGTATCTCTGATATTTTTTGCCAGAATCATCATGTCATGTATGAATGTGTTATCCCTATCTAAGGAAAAAGGTGAATATGTTTTTGTATGAATGTTTAACTGGAAATGTCCATGGACTTGGCTAATTTATATTTACTTTTTATTGTACATAGATTTCTAATATTTTTCATTCCTGTATCATTTAAACTTCCTTCATTTGAGTAAATTCACTAAAtatttctattttttgcttttttaaattctgattttatatgaattctaattctttttcACTACATATGTTTTAAAGAGTTACATACAGTGATTTAGAATGGTTTACAGTTAATGCTGATCTTGTATTTTAAATTCCAACACTTTGTGTCACTACCTCCTCTAATGGTTAGTATGATATGCTAGCAGACTGTATGAGGTCTTTTTTTAAAATACCACTTTTAGTGTCAGTGAACCAAATTCTGGAATGTCTTAACAGCTCTAAATCTTACTTGTCTTGAAAATGATTGGGGTTTAATACCACTGCTGGTGGTTCACACATCATCCCATCCTTAATATGCCTGACAGGCATCTGAGCAAAGGTTTTTAGTAATTGAATTTCTCTGCAGTAGTCCTTCAAGCACTTGAATGTAAACCTTTAGCATTTATTCGTTTAATGACTACTGATACGAATCTCAAGCAGATTTCTTGCTCTTAAAAGTTATGTTTCACTGAGTTCTGGTTTTGTGTAGCTATATTTTATATAGCTAGATATTCCTCACAGTGAACATGAATTGTAATAATTGGTTATTTCCTTAAGTCTTTAGATTATAATAATTTCAGATTATTGCACGTCTGTGATTTGAGAGGTGAGTTATTTAAGAGGCCAGTTTTCAGGACATGGGAATTTGAATTGTAAACCTGTTATCTCTGTGAAACTTTTAACATGATAAAATATAACCTTTCTTTGTGCTTA

Publications

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