Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ARIH2P1
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Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:28651449-28653612  UCSC
Coordinates (T2T) chr18:28846469-28848632  UCSC
Coordinates (hg19) chr18:26231413-26233576  UCSC
Strand +
Parental Sequence NM_006321.4
Parental seq. overlap 2016 bp
Parental seq. overlap (%) 41%
Genomic Region Intergenic
Retrocopy Summary ARIH2P1, located on chr18:28651449-28653612, is a retrocopy of the parental gene ARIH2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ARIH2
Full Name ariadne RBR E3 ubiquitin protein ligase 2
Also known as ARI2|TRIAD1
Coordinate chr3:48918821-48986382
Strand +
Gene summary The protein encoded by this gene is an E3 ubiquitin-protein ligase that polyubiquitinates some proteins, tagging them for degradation. The encoded protein upregulates p53 in some cancer cells and may inhibit myelopoiesis. Several transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been determined yet. [provided by RefSeq, Nov 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ARIH2P1
Bonobo Pan paniscus ARIH2P1
Gorilla Gorilla gorilla ARIH2P1
Orangutan Pongo abelii ARIH2P1
Gibbon Nomascus leucogenys ARIH2P1
Green monkey Chlorocebus sabaeus ARIH2P1
Crab-eating macaque Macaca fascicularis ARIH2P2
Rhesus Macaca mulatta ARIH2P2
Baboon Papio anubis ARIH2P2
Golden snub-nosed monkey Rhinopithecus roxellana ARIH2P2
Marmoset Callithrix jacchus ARIH2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>ARIH2P1
TGGCTGGACCAGCGTCGGCCCGTCGCCTCCACCTCTGCTGCAGCTGGGCCCCAGTCAGATCCCTCTGGCCCGGCCTGACTTGGTCTGGCTAACCCGGGCTCAGCGGCCATGAAGCCACAGCTCCCGATGGAAATCATATTACATAGAATATTTGGGTGACATCTGCCTGAGAGATCTCCAAGAATTACAGAAAACAAAAATACTAATGCACTTGAGAAAGCGGTAGTTTTGTGGGGAGGCGGAAAAAGCAACTGCTTTTCTGCAACTTGGCTGGATGCTAAGATGTCCGTGGACATGAATAGCCAGGGGTCTGACAGCAATGAAAAGCACTATGACTCAAATTGTGAGGAAGAGGAACAAGAAGAGGATGAAGACCCTGGGGACATAGAGGACTATTACCTGGGAGTAGCCAGCAATGTGGAGCAGCAGGGGGCTGATGCCTTTGATCCTGAGGAGTACTAGTTCACTTACTTGACCTACAAGAAATCTGAGGGTGCCCTGAACGAGCACATGACCAGCTTAGCCTCTGTCCTAAAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCATTGGCAAGTTTCAGAGAGATTGGACAGATACAAGTCCAATTCTGCTCAACTGCTCGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCGCATCTCATCCCCCTCACCTCTGTGCAGTGTGTATGCAGTTTGCGCGAAAGAAAAACCTACTCTCCCTGGTCTGTCAGCACCAGTTTTGCCGTAGCTGCTTGGAGCAGCACTGCTCAGTTCTCGTTAAGGATGGTGTGGGTGTGGGAGTCGCTTGCATGGCTCAGGACTGTCCCACTCCATACACCAGAGGACTTTGTGTTTCCATTGCTTCCCAATGAAGAATTGAGAGAGAAATACAGGTGCTACCTCTTCAGGGACTATGTGAAGAGTCATTACTAGCTCCAGCTGTGCCCTGGTGCAGACTGCCTCATGGTTGTTCGGGTACAGGAGCCTAGAGCTCACCGAGTATAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCATCAAATATATCACGCACCCACAGACCGCATCACCATCCGAAAATGGCTCAAGAAGTGTGCAGACAACTCTGAAACAGCCGACTACAGTAGTGCTCACACTAAAGACTGTCCCGAATACAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGACTTCTGCTGGACATATCTAGGAGATTGGAAGGCACATGGCAGTGAATAATATGAGTGCAGTACTTACAAGGAGAATCCTGACATTGTGAACCAGCGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAAAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAACAAAAGCTTGCAGCTAGAGGCACAGACATACCAGCAGATTCATGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATTGACTGGCAGTACCTACAGAGTGCAGCCAAGCTCTTGGCCAGGTGTTGATACACCCTGCAGTACATCAACCCATATACATATTACATGGAGTCTGGACCCAGGAATGAGCTGTTTGAATACCAGCAGGCTGAGCAGGAGGCTGAAATTGAAAACCTCTCATGGAAAGTGGAACATGCAGACAGCTATGACAGAGGGGACTTGGAGAACCAGATGCATGTAGCCGAGCAGTGGAGGAGAACCCTGCTGAAGGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCGGGGGTGAGGAAGATAAGGCTGCAAGGTCTCCTGGCTGCCCTACTACATGCTGCAGGCTCTGCCTTTCATGACCCCTGGCGACAGCCAGGGCCCCACTCCTGAGAGACACTGGCAACACCTCTTAGTTAATTTCTGTTTTCTTCTCTTCTCACTTTTTGTTTCTGCCAGGGTAGAGGCCATGTTGAACTGGTCTCTTTTCAGGACTTTTACTTCCCCCTGGATGGTTGTTGAGTGGGAGGGAAAGTGTTTTTTGGATAGCTATTAATAATATTAGATCATTACAACTTATGTAACTTTCAAAGTTTGTACAATTATACAAAAAAAGGCAAACTATAGGATAACACAGAGCCCTTTTTGAAAATAAATTGGCATTGGAGTGT
>NM_006321.4
GGAGCTGTGGGGACGACTCTTCTGGAGGAAGCAGCGCGGGCTTGACCGGCGTCGGCCCGCCGCCTCCGCTGCCGCTTCGCCCCAATCCGGTCCCTCTGGCCCGGCCTGACCCGGTCTGGCTTGTTCGGGCTCAGCGGCCGCGAGGCCGCAGCTCCCGATGGAAATCATATTATGTAGAATACTTGGGTGACATCTGCCTGAGAGATCTCCAAGAATTACAGAAGACAAAAATACTAATGCATTTGAGAAAGCGGTAGTTTTGGGGGGAGGGGGAAAAAGCAACTGCTTTCCTGATCTGCAACTTGGCTGGATGCTAAGATGTCAGTGGACATGAATAGCCAGGGGTCTGACAGCAATGAAGAGGACTATGACCCAAATTGTgaggaagaggaagaagaagaagaagacgaCCCTGGGGACATAGAGGACTATTACGTGGGAGTAGCCAGCGATGTGGAGCAGCAGGGGGCTGATGCCTTTGATCCCGAGGAGTACCAGTTCACTTGCTTGACCTACAAGGAATCTGAGGGTGCCCTCAATGAGCACATGACCAGCTTAGCTTCTGTCCTAAAGGTATCTCATTCAGTTGCTAAACTTATATTAGTTAATTTCCACTGGCAAGTTTCAGAGATATTGGACAGATACAAGTCCAATTCTGCTCAACTGCTTGTTGAGGCTCGAGTTCAGCCTAATCCATCAAAACATGTTCCCACATCCCATCCCCCTCACCACTGTGCAGTGTGTATGCAGTTTGTGCGAAAGGAAAACCTACTCTCTCTGGCCTGTCAGCACCAGTTTTGCCGCAGCTGCTGGGAGCAGCACTGCTCAGTTCTCGTCAAGGACGGCGTGGGCGTGGGAGTCTCTTGCATGGCTCAGGACTGTCCACTCCGTACACCAGAGGACTTTGTGTTTCCATTGCTTCCCAATGAAGAATTGAGAGAGAAATACAGGCGCTACCTCTTCAGGGACTATGTGGAGAGTCATTACCAGCTCCAGCTGTGCCCTGGTGCAGACTGCCCCATGGTTATTCGGGTACAGGAGCCTAGAGCTCGCCGAGTACAGTGCAATCGGTGCAACGAGGTCTTCTGTTTCAAGTGTCGTCAGATGTATCACGCACCCACAGACTGTGCCACAATCCGGAAATGGCTCACGAAGTGTGCAGACGACTCTGAAACAGCCAACTACATTAGTGCTCACACTAAAGACTGTCCCAAGTGCAACATCTGCATTGAGAAGAATGGAGGCTGCAATCACATGCAATGCTCCAAATGTAAACACGacttctgctggatgtgtctaggagattggaagactcatggcagtgaatacTATGAGTGCAGTCGTTACAAGGAGAATCCTGACATCGTGAACCAGAGCCAACAAGCCCAGGCGAGGGAAGCCCTCAAGAAGTACTTATTCTACTTTGAGAGGTGGGAAAACCACAATAAAAGCTTGCAGCTAGAGGCACAGACATACCAGCGGATTCACGAGAAGATTCAGGAGAGGGTCATGAACAATCTGGGGACATGGATCGACTGGCAGTACCTACAGAATGCTGCCAAGCTCTTGGCCAAGTGTCGATACACCCTGCAATACACCTACCCATATGCATATTACATGGAGTCCGGACCCAGGAAGAAGCTGTTTGAATACCAGCAGGCTCAGCTGGAGGCTGAGATCGAAAACCTCTCATGGAAAGTGGAGCGTGCAGACAGCTATGACAGAGGGGACTTGGAGAACCAGATGCATATAGCGGAGCAGCGGAGGAGAACCCTGCTGAAAGATTTCCATGACACCTAAGTTGGGATGTGGATGTGCCGGGGTGAGGAAGATGTGGCTGCAAGGTCTCCCGGCTGCCATACTGCATGCTGCAGGCTCTGCCTTTCATGACCCCAGGCAACAGCCAGGGCCCCACTCCTGAGAGACACTGGCAACACCTCTTAGTTGATTTCTGTTTTCTTCTCTTTTCACTTTTTGTTTCTACCAGGGTAGAGGCCATGTTGAACTGGCCTCTTTTCAGGACTTTTATTTCCCCCTGGATGGTTGTTGGGAGGGAGGGAAAGTGTTTTCTGAATGGCTATTAATAGTATTAGATCATTACAACTTATGTAACTTTCAAAGGTTGTACAATTATACAAAAAAAAAAAAAAGGCAAACTATAGGATAACACAGAGCCCTTTTTGAAAATAAATTGGCATTGGAGTGTTTTACCCTCTAGCTGTTTTACTTAGAATGTAACATATGCTGCCTACCCACCTCAAAATGTCTGTACTGCAAGAGGGCCCTGGGCCTCTGCTTTCCATATTCACGTTTGGCCAGAGTTGTAGTCCCAAAGAAGAGCATGGGTGGCAGATGGTAGGGAATTGAACTGGCCTGTGCAATGGGCATGGAGCACAAGGGGTCACAGCATGCCTCCTGCCTTACCGTGGCAGTACGGAGACAGTCCAGAACATGGTCTTCTTGCCACGGGGTGTTGTTGTCTCTGGTGGTGCTGCATGTCTGTGGCTCACCTTTATTCTTGAAACTGAGGTTTACCTGGATCTGGCTACTGAGGCTAGAGCCCACAGCAGAATGGGGTTGGGCCTGTGGCCCCCCAAACTAGGGGGTGTGGGTTCATCACAGTGTTGCCTTTTGTCTCCTAAAGATAGGGATCTACTTTTGAAGGGAATTGTTCCTCCCAAATAAATTTGCTTTACCTTGGTCCTTTCTTTTGTGCCAGTATTCAAGTGGTATAGCTCTGAGCAGGGTCACATTTGGCCAAACCTGACACTGTCTTGCTGCATTCTCCTTTGGCAAACATCAGGGTCAGAATTCAGGATAGCCCTTCCTAGGGCACTGGACTTTCTGGCATGGGGGCTGTGTTTGCACAAGTTATTTTCATGTTACCTGGAGAGTGTCCAGAGGCTGCTCTGAGGCTGAGGTGTGTTCCCCCTTGCCTGGTTCCAGCTGTCAGAGGGATACCATCCTAGGGTCTGGGAATCCAAGGCCACGAGACTCCTTGGTTTGTGGTCCGAGATCCTGTACTAAGGAGGGTCTGGCCAGAGGAACAGACCAGCTTTTGCACAATGAAGCGCAAGGGAACAAGTGGTTTGCCTGGTGTCCTACCTGTCCTGAACCTGGTCCTGTGGGCCATTGAAAAGTTAGATCTGTGATCTCTGGGGTTTTTGTGGCTTTGTTCAATGCTTCCACTCTAGGGCAGGCAGAGCAGTCTATACTCTCCCAAGCCTGCTTGACCTCCAAGTAGAGCTGATACAGAGATCTGTGAATATTGTGATAGAAATTCTTTGGTATTCATACATTTCAGCTGCAAGTCAGCAATTTCCCAGGTACCATGTAAGCTATAAAACAGTCATTCTTAAAGACAGAGGATAGCTGTGACTCATGGGATCATGAGGTCCATGGCTGGTTGCAGGTTCCCTTTTTCCTTCCTCAGGTTTTGTCTCTTCCTGTGTTGTCCCCAGCAAGGGAGAGACTGTGGGGTGGATTGGGAGAACAGATTAGGAGTATAGCAAATGAACCCAGAATGGAACAGTGGGGAGCTAACTGTGAATGAGGAGAGTACCTGCTGCAGGACCTGGAGGTCAGGTGTGAATGCTGTATTGGCACAGGGAATAAATATCCTGGCGTCTGGAGCCTTCACCTCTCCGTCAAGTCCTTCCTGTGATACTGCCATGGCACAGGATCTGAGTTGCAGCTCTGCACCCTAAATCACACCCTGGGCATTGTCTGGGCTGCAGGGCTGCCAGGTTCTGTACTTGTGTCCAGCTGTGGCCCTGGATGCTGGAGCTGGAGGGTTTTCTGTGCTCAGACTGTAGCCTGTAGCTCTTGGCCTGTGTAGAGCCCCCTCCTGTGCCCTCAGTGGCTGTCGTTTGTTAACATCATCAGGAAGATGGGAAAGGTCAGGCAGAATTTTTCTGCCCTACAAAGGGTGGAAGAGAAAGGACACAGTATTTTCATGAATTTACCATATATCTTTGTTTTTCTTCAACGAAAAAGTTAATTGAGGCAATGTCATCTGCTCAAAGTTGAGTGGTTTATTCACAATAAACTGTAAGTTTCTGATTATAAAAATGTGTCTAGAGTCTTTCTTCATGGGGTCTAGGTAGTCTTCTGAGCCCACAGGGGTCTGGCCAGTGAACACCAGAGGAGTGCCTTCCTATCAGTCAGCCCCTTCTTCCAGAGGGCTGTGGAGGCCCCAGTGGCCAAACTCGGCTCTGTTTTCCCTTTCTGGCTGTTGGGGGAGAGGGCACCTGTAAGTGATCCCTGTGGAATGAAGTAGAAAATCCTGCCAGTTTTCCGCTCTCCTCTCCCTCAGTACAGGCTGAATCATTCCCCACCACAGATAGATCCCAGGGTTGTGGTAGAGTACTGATATAAATGTCCCAACCCCCCCATTCTGAGACCTCCGGACCCCTCCAAAGCAGACATGGGAATGTAGGGCTGTGGAATATGGCAGGGTGAACTCCAGCTTCACGGGAGCCCTAAGGGTTATGAAGAGACAACTTGGGGCAGAAACAAGTGTGGAGTCTAATCTCAAGGGTGAAGGACAGGAAATGAGGTTTGGATTGATTAAGGGGGTCCACATTTGTGGTGTCAGAAGTGGCAGTAGTGTCAGTGATAAGTAGCTCAGGGGTAGAGTGGAGGCTCCATAGCTGTGGGCAACATGCACAGGGCACCTGTGGCTAGAAGAGGCCTCATACATTGCCAGTCTGAACTCCGCAGCTCTTCCTCTGGACCTCAGgtgtgccaagccccacgcttggcacctgggcatacagtggtatgcaagtgattcacgtgctctagcttccaggagcttccaatccatggggaacatagaAGGAATTGATCACTAGTGAATGtttgttttttgttttgagacagtctcgctctatcgcccagactggagtac

Publications

PMID - Link Title
No publications available for this retrocopy