Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HSPA9P2
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:29256143-29257060  UCSC
Coordinates (T2T) chr18:29445660-29446577  UCSC
Coordinates (hg19) chr18:26836108-26837025  UCSC
Strand -
Parental Sequence NM_004134.7
Parental seq. overlap 854 bp
Parental seq. overlap (%) 19.3%
Genomic Region Intergenic
Retrocopy Summary HSPA9P2, located on chr18:29256143-29257060, is a retrocopy of the parental gene HSPA9. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HSPA9
Full Name heat shock protein family A (Hsp70) member 9
Also known as CRP40|CSA|EVPLS|GRP-75|GRP75|HEL-S-124m|HSPA9B|MOT|MOT2|MTHSP75|PBP74|SAAN|SIDBA4
Coordinate chr5:138553756-138575401
Strand -
Gene summary This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HSPA9P2
Bonobo Pan paniscus HSPA9P2
Gorilla Gorilla gorilla HSPA9P2
Orangutan Pongo abelii HSPA9P1
Gibbon Nomascus leucogenys HSPA9P1
Green monkey Chlorocebus sabaeus HSPA9P3
Crab-eating macaque Macaca fascicularis HSPA9P3
Rhesus Macaca mulatta HSPA9P3
Baboon Papio anubis HSPA9P3
Golden snub-nosed monkey Rhinopithecus roxellana HSPA9P3
Marmoset Callithrix jacchus HSPA9P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HSPA9P2
AATTCAAGGACCAATTACCTGCTGATAAGTGCAAAAGCTAAAAGAAGAGATTTCCAAAATGAAGGGGCTTCTGGATAGAAAAGACAGCGAAACGGGAGAAAACATTGGACAAACAGCATCCTCTCTTCAGCAGGCATCACTGAAGCTCTTCGAAATGGCATACAAAAAGATGGCATCTGAGCAAGAAGGCTCTGGAAATTCTGGCACTGGGGAACAAAAGGAAGATCAAAAGGAGGAGAAACAGTAATAATAGCAGAAATTTTGAAGCCAAATTGGACAACATATGAAGCTTAGGAGCAAAGAGACTTCCTGAGCAGAAATGGGCAAACTTCAGTCTTTTTACTGTGTTTTTGCAGTGTTCTATATATAATTTCCTTAATTTGTAAATTTAGTGACCATTAGCTAGTGATCATTTTATGGAAAGTGATTCTAAAGGTATAAAGTTCACAATGTTCTATGTCCCTGGACTGTCATTTTTCAGCTGCATGTAAAAGGGGTAGGATGAATTAACTGGTCATTATAAAGATTTAACTATTGTATGCTGAAGTGGCCATATTTTCAAGGGGTGAAAACATTTCACACACAACAATGAAGGTAATCAGCCATAGACTTGGAATGAGACCACATATGGGGATGAGATCCTTCCCCAGTAACCTAGTACTGCTGTACTGGCCTATGTGTACATGGGGTCCTTCAACTGAGGCCTTGCAAGGCAAGCTGGCTGTGCCATGTTTGTAGATGGGGCAGAGGAAGCTAGAACAATGGAAAACTAAGCTATTTATGTGAGGTACAGCTATTAAAACAAGGCAGGAATGAGGCTAGGCCCTTAATTTCCCTAAGGCATACTTTTCTAGCTACCTTCTGCCCTGTGTCTGGCACCTACATCCTTGATATTTGTTCTCTTTTATCCATTCTGGG
>NM_004134.7
AGAAGCGCTGCCGCCACCGCATCGCGCAGCTCTTTGCCGTCGGAGCGCTTGTTTGCTGCCTCGTACTCCTCCATTTATCCGCCATGATAAGTGCCAGCCGAGCTGCAGCAGCCCGTCTCGTGGGCGCCGCAGCCTCCCGGGGCCCTACGGCCGCCCGCCACCAGGATAGCTGGAATGGCCTTAGTCATGAGGCTTTTAGACTTGTTTCAAGGCGGGATTATGCATCAGAAGCAATCAAGGGAGCAGTTGTTGGTATTGATTTGGGTACTACCAACTCCTGCGTGGCAGTTATGGAAGGTAAACAAGCAAAGGTGCTGGAGAATGCCGAAGGTGCCAGAACCACCCCTTCAGTTGTGGCCTTTACAGCAGATGGTGAGCGACTTGTTGGAATGCCGGCCAAGCGACAGGCTGTCACCAACCCAAACAATACATTTTATGCTACCAAGCGTCTCATTGGCCGGCGATATGATGATCCTGAAGTACAGAAAGACATTAAAAATGTTCCCTTTAAAATTGTCCGTGCCTCCAATGGTGATGCCTGGGTTGAGGCTCATGGGAAATTGTATTCTCCGAGTCAGATTGGAGCATTTGTGTTGATGAAGATGAAAGAGACTGCAGAAAATTACTTGGGGCACACAGCAAAAAATGCTGTGATCACAGTCCCAGCTTATTTCAATGACTCGCAGAGACAGGCCACTAAAGATGCTGGCCAGATATCTGGACTGAATGTGCTTCGGGTGATTAATGAGCCCACAGCTGCTGCTCTTGCCTATGGTCTAGACAAATCAGAAGACAAAGTCATTGCTGTATATGATTTAGGTGGTGGAACTTTTGATATTTCTATCCTGGAAATTCAGAAAGGAGTATTTGAGGTGAAATCCACAAATGGGGATACCTTCTTAGGTGGGGAAGACTTTGACCAGGCCTTGCTACGGCACATTGTGAAGGAGTTCAAGAGAGAGACAGGGGTTGATTTGACTAAAGACAACATGGCACTTCAGAGGGTACGGGAAGCTGCTGAAAAGGCTAAATGTGAACTCTCCTCATCTGTGCAGACTGACATCAATTTGCCCTATCTTACAATGGATTCTTCTGGACCCAAGCATTTGAATATGAAGTTGACCCGTGCTCAATTTGAAGGGATTGTCACTGATCTAATCAGAAGGACTATCGCTCCATGCCAAAAAGCTATGCAAGATGCAGAAGTCAGCAAGAGTGACATAGGAGAAGTGATTCTTGTGGGTGGCATGACTAGGATGCCCAAGGTTCAGCAGACTGTACAGGATCTTTTTGGCAGAGCCCCAAGTAAAGCTGTCAATCCTGATGAGGCTGTGGCCATTGGAGCTGCCATTCAGGGAGGTGTGTTGGCCGGCGATGTCACGGATGTGCTGCTCCTTGATGTCACTCCCCTGTCTCTGGGTATTGAAACTCTAGGAGGTGTCTTTACCAAACTTATTAATAGGAATACCACTATTCCAACCAAGAAGAGCCAGGTATTCTCTACTGCCGCTGATGGTCAAACGCAAGTGGAAATTAAAGTGTGTCAGGGTGAAAGAGAGATGGCTGGAGACAACAAACTCCTTGGACAGTTTACTTTGATTGGAATTCCACCAGCCCCTCGTGGAGTTCCTCAGATTGAAGTTACATTTGACATTGATGCCAATGGGATAGTACATGTTTCTGCTAAAGATAAAGGCACAGGACGTGAGCAGCAGATTGTAATCCAGTCTTCTGGTGGATTAAGCAAAGATGATATTGAAAATATGGTTAAAAATGCAGAGAAATATGCTGAAGAAGACCGGCGAAAGAAGGAACGAGTTGAAGCAGTTAATATGGCTGAAGGAATCATTCACGACACAGAAACCAAGATGGAAGAATTCAAGGACCAATTACCTGCTGATGAGTGCAACAAGCTGAAAGAAGAGATTTCCAAAATGAGGGAGCTCCTGGCTAGAAAAGACAGCGAAACAGGAGAAAATATTAGACAGGCAGCATCCTCTCTTCAGCAGGCATCACTGAAGCTGTTCGAAATGGCATACAAAAAGATGGCATCTGAGCGAGAAGGCTCTGGAAGTTCTGGCACTGGGGAACAAAAGGAAGATCAAAAGGAGGAAAAACAGTAATAATAGCAGAAATTTTGAAGCCAGAAGGACAACATATGAAGCTTAGGAGTGAAGAGACTTCCTGAGCAGAAATGGGCGAACTTCAGTCTTTTTACTGTGTTTTTGCAGTATTCTATATATAATTTCCTTAATTTGTAAATTTAGTGACCATTAGCTAGTGATCATTTAATGGACAGTGATTCTAACAGTATAAAGTTCACAATATTCTATGTCCCTAGCCTGTCATTTTTCAGCTGCATGTAAAAGGAGGTAGGATGAATTGATCATTATAAAGATTTAACTATTTTATGCTGAAGTGACCATATTTTCAAGGGGTGAAACCATCTCGCACACAGCAATGAAGGTAGTCATCCATAGACTTGAAATGAGACCACATATGGGGATGAGATCCTTCTAGTTAGCCTAGTACTGCTGTACTGGCCTGTATGTACATGGGGTCCTTCAACTGAGGCCTTGCAAGTCAAGCTGGCTGTGCCATGTTTGTAGATGGGGCAGAGGAATCTAGAACAATGGGAAACTTAGCTATTTATATTAGGTACAGCTATTAAAACAAGGTAGGAATGAGGCTAGACCTTTAACTTCCCTAAGGCATACTTTTCTAGCTACCTTCTGCCCTGTGTCTGGCACCTACATCCTTGATGATTGTTCTCTTACCCATTCTGGAATTTTTTTTTTTTTAAATAAATACAGAAAGCATCTTGATCTCTTGTTTGTGAGGGGTGATGCCCTGAGATTTAGCTTCAAGAATATGCCATGGCTCATGCTTCCCATATTTCCCAAAGAGGGAAATACAGGATTTGCTAACACTGGTTAAAAATGCAAATTCAAGATTTGGAAGGGCTGTTATAATGAAATAATGAGCAGTATCAGCATGTGCAAATCTTGTTTGAAGGATTTTATTTTCTCCCCTTAGACCTTTGGTACATTTAGAATCTTGAAAGTTTCTAGATCTCTAACATGAAAGTTTCTAGATCTCTAACATGAAAGTTTTTAGATCTCTAACATGAAAACCAAGGTGGCTATTTTCAGGTTGCTTTCAGCTCCAAGTAGAAATAACCAGAATTGGCTTACATTAAAGAAACTGCATCTAGAAATAAGTCCTAAGATACtatttctatggctcaaaaataaaaggaacccagatttctttccctatttctgcttttctgtcctcagtgtactggcttgtccCAAATTCTCTGATGTAGTTCTAATAATTATCATGTGCTGACAACCTGAGCAGAAAGGCAACTACATCTTTATTCAATGTTAAGATTTCCCAAAAGTCTTCCAGCACATTTCCCTTATGTTTCATGGATGAATGTCATATGCCATGTTCAAAAGAGTCTGTTATCAAGATGGGCTTAGAATATCAGACACAATGGCTCCTTTTATAATGTTTTGTAATATGTAGAAATGAGATTACTGTATTTCCAAAAATCAGTATAAGAAATCAATTTAATTTGCAAGTATGAAGGAAGTGATTTAGACAACATTTTTGGAAGATTCAGTGCTTGTTAACACCCATGTAAAAGATTCTTGGGATTCGTGAAAAATTCTAGGCTCAGGTTTCCAACCACATGAACACTCAATGGGAACATTGTAGGATTATGAAGGATTGTTATATGGTGTGTTGGAAAATAACTTTTAGCATTTTTGGTTGGCCCTTGCCCACTGCCTCTACTGTCTCCTAAAGATAACTTTAAAAGCCCTCCAGGATTTCCAAAGTACTCCAGTTGAGAACTACTGGCTTAATGCTAGTCAAGATTCATCCTTGGGATCAGAGAGAGGAGCCAAATGCCCAAGCAAAATATATATTTGAGTTCTATTAGGAGGGAGAAGTTGCTTGGGTATGGGTGGACACAGTATTTCAGTCACCTATCAGTAAAGCTAATAGCATAAATAGCAAGAAGGTATATGGAGATTTCCTacagccaataggatatatatctagaataagatttactgtaagaaagaaactggctcacaattatggaaccgaggtcccacccacagtccactgctgggaaagctgttggggtaaaatttcagtgaccaggaacacagtggtgtcctagtccgaggttagaagaatatggatgtcttagctctggcagttctatataggcccttaactgattagatgatgtccactcacatcaaagcagagcaatctccaattcaatactaatctcttctggagagagacaaatgtttaacccgttaaatggcatcaatggctaaactgacacataaaattaactatcacaAAAGGCAAAAA

Publications

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