Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name WBP11P1
Plot displaying the genomic locations of a retrocopy (in chr18) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr18:32511812-32513050  UCSC
Coordinates (T2T) chr18:32702115-32703353  UCSC
Coordinates (hg19) chr18:30091775-30093013  UCSC
Strand +
Parental Sequence NM_016312.3
Parental seq. overlap 1153 bp
Parental seq. overlap (%) 25.1%
Genomic Region Intergenic
Retrocopy Summary WBP11P1, located on chr18:32511812-32513050, is a retrocopy of the parental gene WBP11. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name WBP11
Full Name WW domain binding protein 11
Also known as BUG13|CFAP90|FAP90|NPWBP|PPP1R165|SIPP1|VCTERL|VCTRL|WBP-11
Coordinate chr12:14784582-14803478
Strand -
Gene summary This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes WBP11P3
Bonobo Pan paniscus WBP11P3
Gorilla Gorilla gorilla WBP11P3
Orangutan Pongo abelii WBP11P2
Gibbon Nomascus leucogenys WBP11P1
Green monkey Chlorocebus sabaeus WBP11P2
Crab-eating macaque Macaca fascicularis WBP11P3
Rhesus Macaca mulatta WBP11P3
Baboon Papio anubis WBP11P2
Golden snub-nosed monkey Rhinopithecus roxellana WBP11P3
Marmoset Callithrix jacchus WBP11P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>WBP11P1
tAAATGAACAAGTAAACCATACAAATTGTCAACATGGGAAGGAGATCTGCATCATCCACCAAGAGTGGAAAATTTATGAACCCCACAGACCAAGCCCGAAAGGAAGCCCGGAACAGAAGAACAAAAAACAGCTCATGATGGTTTGAGCTGAAGTTTTAAAGATGAAGGATCCCAAACAGATGATCCGAGACATGGAGAAATTGGATGAAATGGAGTTTAACCCAGTGCAACAGCCACAATTAAATGAGAAAGTACTGAAAGACAAGCGTAAAAATAGCTGTGTGAAACCTTTGAACATATTCTATGACTCTATGAAAAAGAGGATCCAGATATTTAGAAAGAATTGAGAAAGCTAGAAATAGAGTATGAACAGAAGAGGACTCAACCAATATTTGAATGCTGTCGAGAATGCCCAGCACGTGGAAGTGGAGAGTATTCCTTTACCAGATATGCCACATGCTTCTTCTAACATTTTGATCCAGGAAATTCCACTTCCTGGTGCCCAGCCACCCTCCATCCTTAAGAAACCCTCAGCCTGTGGACCTCCAACTCAGGCAGTTTCTATCCTTCTCTTCTTGGGACGTGGTGTTCCACATTTGCCTCCTGGCAGAAAACCTCTTGGCCCTCCCCCTGGTCCACCCCCTCCTCAAGTCGTGCAGATGTATGGCCGTAAAGTGGGTGTTGCCCTAGATCTTCCCCCTCCTAGGTGAGATGAAGGCATGGTACATAGTCCTGAAATTGCCCAGCGAGGTCATGATGATGATGTTTTTAGCACCAGTGAAGATGATGGCTATCCTGAGGACGTGGATCAAGATAAGCATGATGACAGTACTGATGACAGTGACACCGACGGATCAGATTGAGAAAGTGTGCGCCATGATGATGGTGGGAGAGACAACAATGAAAAAAAGAAGTCAGGTCTGAGTGTACGGTTTGCAGATATGCCTGGAAAATCAAGGAAGAAAAAAACCATGAAGGAACTGACTCCTCTTCAAGCCACGATGCTTCGTATGGCAGGTCAAGAAATCCCTGAGGAGGGACGGGAAGTAGAGGAATTTTCAGAGGACAATGATGAAGATGATTCTGATGACTCTAAAGCAGAAAAACAATCACAAAAACACAATCAAGAGGAACTGCATTCTGATGGCACATCCACTGCTTCTTCACAGCAGCAGGCTCCCCGGCAGTCTGTTCCTCCTTCTCAGGTACAAGCACCTCCCATGC
>NM_016312.3
GCGAGGTTTCAAGATGGCGGTAGCTGAGGGGTTGACCGAGAGACCCAGTTGAAGGCCTTTACGAAGTGAAAGAGGCCGGGAGTCGCCCCCTACCCGCTTCTCGTAGTCCTGGGAGCACAGCAGAAGTGTTTTTCTTTTTTTAATGAACAAGTAAACCATACAAATTGTCAACATGGGACGGAGATCTACATCATCCACCAAGAGTGGAAAATTTATGAACCCCACAGACCAAGCCCGAAAGGAAGCCCGGAAGAGAGAATTAAAGAAGAACAAAAAACAGCGCATGATGGTTCGAGCTGCAGTTTTAAAGATGAAGGATCCAAAACAGATAATCCGAGACATGGAGAAATTGGATGAAATGGAGTTTAACCCAGTGCAACAGCCACAATTAAATGAGAAAGTACTGAAAGACAAGCGTAAAAAGCTGCGTGAAACCTTTGAACGTATTCTACGACTCTATGAAAAAGAGAATCCAGATATTTACAAAGAATTGAGAAAGCTAGAAGTAGAATATGAACAGAAGAGGGCTCAACTTAGCCAATATTTTGATGCTGTCAAGAATGCTCAGCATGTGGAAGTGGAGAGTATTCCTTTGCCAGATATGCCACATGCTCCTTCCAACATTTTGATCCAGGACATTCCACTTCCTGGTGCCCAGCCACCCTCTATCCTAAAGAAAACCTCAGCCTATGGACCTCCAACTCGGGCAGTTTCTATCCTTCCTCTTCTTGGACATGGTGTTCCACGTTTGCCCCCTGGCAGAAAAcctcctggccctccccctggtccacctcctcctcAAGTCGTGCAGATGTATGGCCGTAAAGTGGGTTTTGCCCTAGATCTTCCCCCTCGTAGGCGAGATGAAGACATGTTATATAGTCCTGAACTTGCCCAGCGAGGTCATGATGATGATGTTTCTAGCACCAGTGAAGATGATGGCTATCCTGAGGACATGGATCAAGATAAGCATGATGACAGTACTGATGACAGTGACACCGACAAATCAGATGGAGAAAGTGACGGGGATGAATTTGTGCACCGTGATAATGGTGAGAGAGACAACAATGAAGAAAAGAAGTCAGGTCTGAGTGTACGGTTTGCAGATATGCCTGGAAAATCAAGGAAGAAAAAGAAGAACATGAAGGAACTGACTCCTCTTCAAGCCATGATGCTTCGTATGGCAGGTCAAGAAATCCCTGAGGAGGGACGGGAAGTAGAGGAATTTTCAgaggacgatgatgaagatgattctgatgaCTCTGAAGCAGAAAAGCAATCACAAAAGCAGCATAAAGAGGAATCCCATTCTGATGGCACATCCACTGCTTCTTCACAGCAGCAGGCTCCGCCGCAGTCTGTTCCTCCTTCTCAGATACAAGCACCTCCCATGCCAGGACCACCACCTCTTGGACCACCACCTGCTCCACCATTACGGCCTCCTGGGCCACCTACAGGCCTTCCTCCTGGTCCACCTCCAGGAGCTCCTCCATTCCTGAGACCACCTGGAATGCCAGGACTCCGAGGGCCCTTACCCCGACTTTTACCTCCAGGACCACCACCAGGCCGACCCCCTGGCCCTCCCCCAGGTCCACCTCCAGGTCTGCCTCCTGGTCCCCCTCCTCGTGGACCCCCACCAAGGCTACCTCCCCCTGCACCTCCAGGTATTCCTCCACCTCGTCCTGGCATGATGCGCCCACCTTTGGTGCCTCCCCTTGGACCTGCCCCCCCTGGGCTGTTCCCACCAGCTCCCTTGCCAAACCCTGGGGTTTTAAGTGCCCCACCCAACTTGATTCAGCGACCCAAGGCGGATGATACAAGTGCAGCCACCATTGAGAAGAAAGCCACAGCAACCATCAGTGCCAAGCCACAGATCACTAATCCCAAGGCAGAGATTACTCGATTTGTGCCCACTGCACTGAGAGTACGTCGGGAGAATAAAGGGGCTACTGCTGCTCCCCAAAGAAAGTCAGAGGATGATTCTGCTGTGCCTCTTGCCAAAGCAGCACCCAAATCTGGTCCTTCTGTTCCTGTCTCAGTACAAACTAAGGATGATGTCTATGAGGCTTTCATGAAAGAGATGGAAGGGCTACTGTGACAGCTTTTGATGCCAGAAAAGGCTTCTGTTCACAACAGTGGCCCATGGAGAAAGAGGCTCTTATTAAACTTAGATGAAAGAGCTGCTTCCATTGTCAGGGTATTTTCTAATTTCAGTTCAAGGAATATCCTAAAATTTAGCCTTGTTCAGAATTTACTGCACATAAAAAAGGGTATTTCATCCAGAATAGATCAGTTATTGAAGCAGTGCTGCTAACATCCATTCCCTTTCATACCACCATTTTCACCCTGTTTCTTCCCCTCCTCCAGTTCTTTGGAAATTTGTGATCGGGGGATCTTAGTTGCTTATTTGTTTTGACTCTTGTGTGCTGTGGGCACTGGAGTAGAGATTTCTGGAGAAAAAAAAACAGTTTATTTCATCTTGCCTTTTGTGTTTGAGTTATTTTTAATATTTTCCTGTAAATATTTTGTAATATTTTACTTGTAATGAAATGGATCACAATGTCATTTCCTAATACAAGGCAGGATATGTGGGAAGAATATGTACAATTATTTGATTAAAATTATTTCCCACTGACCTAAACTTTCAGTGATTTGTGGGAAAAATAAATAAATGTTCTACACCAAGATACTCTGTGTTACTGATAATATGTAAACATAATACCTATTTTATGGACAGAAAAAGTTAAATATTTAAAACTTGGGTCTTTAAGGAACTGCCTTTCTGGTACAGAATGAGAATCTTACTGAAAACATGGTAAAAACTACATTTTAAATTTTAAGGGATAAAAAGGAGTAATTATTTCCCTTTTTTAAGATTGTCATACTGGCTTTAGAGAAACTGAGAGGTGTTAAGAATAGTATGGTTTGGCTTTTATTATTTAAAAGATGTCTTACCTTCAGTGGTTACTTATTCCAGAGCTTCTTGAACTGATACGAGTTGAATGGCAAAAGTCATTTTAAACCATTTTTAAGCTATAAAAGAATCAGAAGAGGTTAGCTTTTTTTCCTTTCTGAATTGGTGGGTTTGGTGTGCTTTTATATTAAAATATGAATGAATAAGAGTGCTTAACATTAATTTGCATTTATACCATTTTCTTTACAAAGTGCTTTAATGTAAACTCATCTACCAATTTAGACTAACTCTTAGTAAGTTTAATGTTAATTTAATGACTAACTCATCTACCAATTAACCCTATAGATAACTTTTCTGGGtattttccccattttacattagagagtattgaaacttaaaaaggactcgtgatttatccaGTGATCCAAAGTGTGTATTTCATAAACACATACACACAGTGCGTGCATTGTTTAGGCATACGTTACTTTCCACAGTATCTCAAATGCCTTTTACATGAATCCCATACTATCAAAAATTGGTGATAACCTAAAATGTAGTGCAATAATACAATAAGGCATTTATTTTCTTAGAGTTGAGTTGATGGATTTTTAGATTTTTATTCAAGATCTTTTGTTTGTTTGGCTTTGCTTGGAAGATACTGATTTATTCTTTCATATTAAAGCAAATCCTGCCAAAGCACTAAATAGACCGTTTTGGGTTGGTTTTTTAGTGTAATATTAATACGGGTCCACAGGTGAATTGAGTCTGTTCAGATGTAAGGATTGAACCTTATGTTATCAATCCTTGACACCATCCTTGATAACTTACGGATATCAAGGATCAAACCATATGGTATCAATATTGTTAGTTATTCAGCATAAACAGAATTATTTCCCAATACTTGATCTGAAATATTTTTAATGGTCTTACTTGAAACTTATATTCTTTCTGGGAGTGATGTTTTTATCATTTTTCCATGgagacaggttctaactctgttgcccaggctgcagtgcagtgatgtgatcatagctcactgcagcctgaaactcctgggttcaagtgatctctggcctcagcctcccaagtagttggaacttcagatacgtgccaccacaaccagctaatttattttttagagatgaggtctcgctatgttgcccagtctggtctcctagcctcaagtgatcttcccatctcagccttcAGTTGGAGATTTCTGATTTATGTTAATATAAGAAAGCTGTTGATAGTTTATCATAAAGGCATTTCCTTATATTGCTAGTATAATTTTCTGAAAATTAGTGGTGTGACAATACATCAGCTGCATCCACAGGAAAGGGGAATTAATTAGCAGTTCTGATTCTGGGTACACTTGTTATGATCATAATTTACATAATATTTTCATGAAAATGGTCAGCTCACAGCTATGAAATGTAAATGATAGAAATCTTTAATCATGTATATGGATAGACTTGTTACTATTTCCTTATCAAAGTGTCACTTTAGGGACAGCAGTTGCCCCTTTAAATTAAGGATCACCACAATAATACTCTGCCATGTCATGGAATCAGCATGAAGCCCTGGATGCTATCCAAGATTCTGTTTCAGTTCTCATTTTGTATATTCTTGTTTGTGCTCTTGATTAAAATATCTCCTTATATATA

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